F W Aelen, T Arts, D G Sanders, G R Thelissen, F W Prinzen, R S Reneman
{"title":"Kinematic analysis of left ventricular deformation in myocardial infarction using magnetic resonance cardiac tagging.","authors":"F W Aelen, T Arts, D G Sanders, G R Thelissen, F W Prinzen, R S Reneman","doi":"10.1023/a:1006089820107","DOIUrl":"https://doi.org/10.1023/a:1006089820107","url":null,"abstract":"<p><p>The Magnetic Resonance (MR) tagging technique provides detailed information about 2D motion in the plane of observation. Interpretation of this information as a reflection of the 3D motion of the entire cardiac wall is a major problem. In finite element models of the mechanics of the infarcted heart, an infarcted region causes motional asymmetry, extending far beyond the infarct boundary. Here we present a method to quantify such asymmetry in amplitude and orientation. For this purpose images of a short-axis cross-section of the ejecting left ventricle were acquired from 9 healthy volunteers and 5 patients with myocardial infarction. MR-tags were applied in a 5 mm grid at end-diastole. The tags were tracked by video-image analysis. Tag motion was fitted to a kinematic model of cardiac motion. For the volunteers and the patients the center of the cavity displaced by about the same amount (p = 0.11) during the ejection phase: 3.8 +/- 1.4 and 3.0 +/- 0.9 mm (mean +/- sd), respectively. Cross-sectional rotation and the decrease in cross-sectional area of the cavity were both greater in the volunteers than in the patients: 6.4 +/- 1.5 vs. 3.0 +/- 0.8 degrees (p < 0.001), and 945 +/- 71 vs. 700 +/- 176 mm2 (p = 0.02), respectively. In the patients, asymmetry of wall motion, as expressed by a sine wave dependency of contraction around the circumference, was significantly enlarged (p = 0.02). The proposed method of kinematic analysis can be used to assess cardiac deformation in humans. We expect that by analyzing images of more cross-sections simultaneously, the 3D location and the degree of infarction can be assessed efficiently.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 3","pages":"241-51"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006089820107","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21336395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Previtali, G Cannizzaro, L Lanzarini, G Calsamiglia, A Poli, R Fetiveau
{"title":"Comparison of dobutamine stress echocardiography and exercise stress Thallium-201 SPECT for detection of myocardial ischemia after acute myocardial infarction treated with thrombolysis.","authors":"M Previtali, G Cannizzaro, L Lanzarini, G Calsamiglia, A Poli, R Fetiveau","doi":"10.1023/a:1006169601499","DOIUrl":"https://doi.org/10.1023/a:1006169601499","url":null,"abstract":"<p><p>In order to compare the ability of dobutamine stress echocardiography (DSE) and exercise Thallium-201 SPECT to detect myocardial ischemia in patients with myocardial infarction (MI) treated with thrombolysis, 43 prospectively selected patients with MI treated with thrombolysis underwent within 1 month from MI DSE, stress-redistribution-reinjection Thallium-201 SPECT and coronary angiography. The echocardiographic and scintigraphic images were analyzed for the presence of myocardial ischemia using a 11-segment left ventricular model. DSE and exercise Thallium-201 SPECT detected myocardial ischemia in the infarct zone in 72% and 72% (31/43) of patients and ischemia at a distance in 12% (5/43) and 19% (8/43) of patients with a concordance of 67% and 88%, respectively. A significant agreement between DSE and exercise Thallium SPECT was found in the evaluation of the extent of both myocardial necrosis and stress-induced myocardial ischemia. DSE and exercise Thallium SPECT showed similar sensitivity (79 vs 76%), specificity (60 vs 60%) and accuracy (77 vs 74%) for detection of a critical stenosis of the infarct-related artery; there was also no significant difference between the tests in sensitivity, specificity and accuracy for detection of the multivessel disease. In conclusion, initially after thrombolyzed MI, DSE and exercise Thallium-201 SPECT detect myocardial ischemia in the infarct zone in a high proportion of patients and show a similar accuracy for the diagnosis of a critical stenosis of the infarct-related coronary artery and of the multivessel disease.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 3","pages":"195-204"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006169601499","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21336429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M R Allen, P A Pellikka, H R Villarraga, K W Klarich, D A Foley, S L Mulvagh, J B Seward
{"title":"Harmonic imaging: echocardiographic enhanced contrast intensity and duration.","authors":"M R Allen, P A Pellikka, H R Villarraga, K W Klarich, D A Foley, S L Mulvagh, J B Seward","doi":"10.1023/a:1006140102056","DOIUrl":"https://doi.org/10.1023/a:1006140102056","url":null,"abstract":"<p><p>The intensity and duration of contrast effect within the left ventricular cavity after an intravenous bolus of Levovist Injection were observed with both harmonic and fundamental imaging in nine patients with known or suspected coronary artery disease. Contrast intensity was assessed by a qualitative grading system (0, none; 1, weak; 2, moderate; 3, good) and by videodensitometric analysis of pixel intensity. Duration of left ventricular contrast effect was determined by measuring time from the initial visual appearance of contrast agent to its disappearance. The mean increase in pixel intensity within the left ventricular cavity from precontrast to peak contrast was significantly greater for second harmonic than for fundamental imaging (25.5 vs 7.1; P < 0.012). The mean contrast intensity qualitative score with harmonic imaging was higher (2.6 +/- 0.73 vs 1.2 +/- 0.44; P < 0.01) and the duration of contrast effect was longer (242 +/- 131 s vs 53 +/- 33 s; P < 0.004). Second harmonic imaging significantly enhanced contrast intensity and prolonged visible duration of contrast effect after a peripheral venous injection of Levovist.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 3","pages":"215-20"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006140102056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21336391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Worsening of left ventricular diastolic function during long-term correction of anemia with erythropoietin in chronic hemodialysis patients--an assessment by radionuclide ventriculography at rest and exercise.","authors":"N Topuzović","doi":"10.1023/a:1006171626861","DOIUrl":"https://doi.org/10.1023/a:1006171626861","url":null,"abstract":"<p><p>We studied the effect of correction of anemia with erythropoietin on left ventricular systolic and diastolic function at rest and exercise in 17 chronic hemodialysis patients by means of maximum exercise testing and equilibrium gated radionuclide angiocardiography on three occasions: 1) initial--before erythropoietin administration, 2) intermediate--at the time when the target hemoglobin level reached 100 g/l, and 3) long-term--after 12 months of therapy. After correction of anemia, the patients showed a significant improvement in their response to exercise regarding maximal work load achieved, exercise duration and recovery time. Ejection fraction and peak ejection rate remained unchanged during therapy. At rest, peak filling rate was reduced from 2.62 +/- 1.0 (baseline) to 2.28 +/- 0.9 (intermediate) end-diastolic volume per second, p < 0.01, while no significant difference was observed during exercise. The time to peak filling rate was prolonged significantly during EPO therapy from 157 +/- 30 to 177 +/- 28 ms at rest, p < 0.05, and from 101 +/- 24 to 130 +/- 27 ms during exercise, p < 0.01. By the time of the late study, there were no significant differences between the late and intermediate study. In conclusion, amelioration of anemia with erythropoietin in hemodialysis patients produced improvement in exercise capacity, but diastolic function worsened with therapy and this effect was maintained during the long-term treatment, while systolic function at rest and exercise remained unchanged.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 3","pages":"233-9"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006171626861","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21336394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R P van Roosmalen, L H Baur, J Braun, D E Atsma, M G Hazekamp, E E van der Wall, H A Huysmans
{"title":"Dynamic obstruction, an unusual complication after aortic valve replacement with a stentless porcine valve.","authors":"R P van Roosmalen, L H Baur, J Braun, D E Atsma, M G Hazekamp, E E van der Wall, H A Huysmans","doi":"10.1023/a:1006189321277","DOIUrl":"https://doi.org/10.1023/a:1006189321277","url":null,"abstract":"<p><p>In the early nineties, the stentless porcine aortic bioprosthesis has been reintroduced successfully. Because of the limited experience, knowledge of clinical complications is limited. Therefore, we describe an unusual complication of dynamic obstruction after aortic valve replacement with a stentless porcine valve in a 70 year old man 18 months after implantation. We discuss the complications of stentless aortic prostheses known so far, describe operative techniques used and their characteristic two dimensional echocardiographic images.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 3","pages":"209-14"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006189321277","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21336392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of flow patterns using MRI.","authors":"M H Buonocore, H G Bogren","doi":"10.1023/a:1006205206534","DOIUrl":"https://doi.org/10.1023/a:1006205206534","url":null,"abstract":"<p><p>This paper describes new software programs for analysis and visualization of blood flow patterns derived from time-resolved 3D velocity data sets. Using the programs, data can be displayed in cross-sectional or 3D perspective view. Particle paths revealing the flow patterns are computed by forward and backward time integration of the velocity field. Vector arrowmaps are computed as short-duration paths starting from uniformly spaced points over the lumen volume. Background, divergence, and local boundary correction is done to improve the realism of the paths. The programs have been used to visualize flow patterns from non-gated and cardiac-gated 3D velocity enclosed data in over 35 subjects. Arrowmaps are preferred for revealing local regions of different blood flow characteristics within the vessel, while particle paths are preferred for revealing global organization of the flow. They are complementary display strategies. Advanced data handling and display features are essential for analyzing and visualizing large velocity encoded data sets.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 2","pages":"99-103"},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006205206534","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21317728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complex flow patterns in the great vessels: a review.","authors":"H G Bogren, M H Buonocore","doi":"10.1023/a:1006281923372","DOIUrl":"https://doi.org/10.1023/a:1006281923372","url":null,"abstract":"<p><p>The article reviews the applications of magnetic resonance velocity mapping based on phase shifts in the protons to quantify blood flow velocity and blood flow volume. The method can be used to study normal physiology of blood flow in the aorta and its major branches, including forward and backward flow, to measure the aortic valve function in aortic valvular disease, stenosis and regurgitation, as well as pulmonary artery flow velocities in pulmonic insufficiency and regurgitation. Superior vena cava flows, pulmonary vein flows, left-to-right shunts, atrial and ventricular pulmonary conduit flows can also be measured. Two- and three-directional velocity mapping is reviewed and can be used to study three- or four-D flows in the aorta and the major arteries in great detail.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 2","pages":"105-13"},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006281923372","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21317729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3D contrast-enhanced MR angiography using fluoroscopic triggering and an elliptical centric view order.","authors":"S J Riederer, S B Fain, D G Kruger, R F Busse","doi":"10.1023/a:1006122514980","DOIUrl":"https://doi.org/10.1023/a:1006122514980","url":null,"abstract":"<p><p>Although a variety of timing techniques and data acquisition strategies have been used for three-dimensional contrast-enhanced MR angiography, many are still limited by inadequate overall reliability, limited spatial resolution, or complexity. A technique is presented in this work in which contrast arrival is detected in the targetted vasculature in real time using MR fluoroscopy. Upon detection the operator triggers a 3D MR angiographic acquisition which uses an elliptical centric view order. It is shown that the view order intrinsically provides a high degree of venous suppression which in turn allows acquisition times of 30 seconds or longer, permitting high spatial resolution. The reliability of fluoroscopic triggering in bolus detection is shown to be over 90%. The technique provides high quality contrast-enhanced MR angiograms for many vascular regions.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 2","pages":"117-29"},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006122514980","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21317731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contrast enhanced body magnetic resonance angiography.","authors":"A E Stillman","doi":"10.1023/a:1006118430910","DOIUrl":"https://doi.org/10.1023/a:1006118430910","url":null,"abstract":"<p><p>The use of gadolinium contrast for body MRA is reviewed. Considerations for timing of the bolus of contrast are discussed. The utility of this technique is illustrated through clinical examples. Contrast enhanced MRA is rapidly replacing conventional angiography for many applications.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 2","pages":"131-7"},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006118430910","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21317732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breathhold cardiac MRI and MRA.","authors":"G G Hartnell","doi":"10.1023/a:1006138713163","DOIUrl":"https://doi.org/10.1023/a:1006138713163","url":null,"abstract":"<p><p>Recent developments in MRI software and hardware have increased the speed and versatility of cardiac MRI by allowing image acquisition in a single breathhold. Many studies have shown that conventional cardiac MRI is as accurate as echocardiography or cardiac catheterization for diagnosing numerous cardiac conditions. In many cases cardiac MRI is the most accurate diagnostic technique but has not been widely adopted for routine cardiac imaging. One reason why the use of cardiac MRI has been limited is the long examination times required for conventional cardiac MRI. The development of better hardware, such as faster gradient amplifiers and dedicated surface coils, has allowed the implementation of much faster EKG-gated imaging sequences. These can be used in a single breathhold period, with a significant improvement in image quality compared with conventional sequences. Breathhold sequences can provide all the information provided by conventional cardiac MRI in a shorter time and with equal or better accuracy. Breathhold imaging will allow much wider application of MRI to routine cardiac diagnosis.</p>","PeriodicalId":77179,"journal":{"name":"International journal of cardiac imaging","volume":"15 2","pages":"139-50"},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006138713163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21317733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}