{"title":"Toxoplasma-macrophage interactions.","authors":"M H Beaman, C S Subauste, S Y Wong, J S Remington","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"60 ","pages":"475-93"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19241003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Macrophage interactions with Candida.","authors":"R Calderone, J Sturtevant","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The monocyte/macrophage, in comparison to the neutrophil, would appear to have a limited role in protection against C. albicans. This statement is based on the observations of several investigators who report that these cells have very little killing capacity unless they are activated by cytokines such as IFN-gamma and GM-CSF. The mechanisms of killing by these cells appear to include both oxidative and nonoxidative mechanisms, the latter perhaps being more important. The mechanisms of killing may be different for monocytes and macrophages. Granulocyte-macrophage colony-stimulating factor and its effect on monocytes has been studied using Candida as a target organism. Two explanations for the enhancement of monocyte killing by this cytokine have been proposed: GM-CSF augments both superoxide anion and the level of mannose receptors on treated monocytes. Both of these changes could be significant in the increased killing capacity of these cells.</p>","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"60 ","pages":"505-15"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19241005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunity and cancer therapy: present status and future projections.","authors":"E. Mihich","doi":"10.1201/9781003067245-30","DOIUrl":"https://doi.org/10.1201/9781003067245-30","url":null,"abstract":"","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"61 1","pages":"293-310"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65953244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antimicrobial mechanisms: antimicrobial polypeptides of mononuclear phagocytes.","authors":"P S Hiemstra, R van Furth","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"60 ","pages":"197-202"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19240424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Macrophage-natural killer cell interactions in resistance to mycobacteria.","authors":"J Y Djeu, M B Michelini-Norris, D K Blanchard","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"60 ","pages":"225-31"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19240426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anti-idiotype antibodies: novel therapeutic approach to cancer therapy.","authors":"K A Foon, M Bhattacharya-Chatterjee","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"61 ","pages":"281-92"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19004964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The immunogenicity of foreign monoclonal antibodies in human disease applications: problems and current approaches.","authors":"R Fagnani","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"61 ","pages":"3-22"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19004966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tumor rejection antigens of the chemically induced BALB/c Meth A sarcoma.","authors":"A B DeLeo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"61 ","pages":"31-6"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19004967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antitumor effector cells: extravasation and control of metastasis.","authors":"T L Whiteside, R H Goldfarb","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To develop effective antimetastatic response, effector cells have to reach the tissue site of tumor metastasis. Different lymphocyte subsets vary in their ability to extravasate and reach sites of tissue injury or tumor growth. The ability of lymphoid cells to extravasate is a function of several different parameters, including cellular activation state and ability to release cytokines, proteolytic enzymes or to respond to chemotactic stimuli present in the tumor microenvironment. Adoptively transferred effector cells can only be therapeutically effective if they extravasate, reach the tumor or its microenvironment and interfere with tumor growth or metastasis. A large number of events that might be involved in accumulation of effector cells such as, e.g., A-NK cells in tumor metastases, are illustrated in the schema in Figure 3. The future challenge will be to gain an in-depth understanding of these events, including effector cell migration and extravasation, to assure optimal transfers of these cells to patients with metastatic disease.</p>","PeriodicalId":77171,"journal":{"name":"Immunology series","volume":"61 ","pages":"159-73"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19005908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}