Changgeng yi xue za zhi最新文献_第8页

Characteristics of hospitalized heroin smokers and heroin injectors in Taiwan. 台湾住院吸食海洛因者与注射海洛因者之特征。

Changgeng yi xue za zhi Pub Date : 1999-06-01

C K Chen, L W Su, S K Lin

{"title":"Characteristics of hospitalized heroin smokers and heroin injectors in Taiwan.","authors":"C K Chen, L W Su, S K Lin","doi":"","DOIUrl":"","url":null,"abstract":"Background: Heroin usage in Taiwan has been under-investigated. Use of the same drug by different routes provides an opportunity for examination of drug behavior and complications related to the drug itself and to the different routes of administration.Methods: A sample of 245 hospitalized heroin users received semi-structured interviews, drug screen urine tests, serological screens for hepatitis B infection, and liver function tests. The sample was divided into a smokers group and an injectors group for comparison.Results: The heroin injectors had lower educational status, spent less money on day-to-day heroin usage, but had longer drug-using careers than the heroin smokers. There was a trend for injectors to have a higher rate of abnormal liver function than the smokers although there was no significant difference in the prevalence of hepatitis B infection.Conclusion: Major differences exist between heroin smokers and heroin injectors. Therefore harm reduction intervention for heroin users should take account of the different routes of administration. A comprehensive survey of risk factors relating to hepatic dysfunction in heroin addicts in Taiwan is indicated.","PeriodicalId":77066,"journal":{"name":"Changgeng yi xue za zhi","volume":"22 2","pages":"197-203"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21356043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brunner's gland hamartomas: report of three cases. 布鲁纳腺错构瘤:附3例报告。

Changgeng yi xue za zhi Pub Date : 1999-06-01

T M Chen, C S Changchien, C C Hsu, T H Hu

引用次数: 0

Maternal urine alpha-fetoprotein concentrations between 14 and 21 weeks of gestation. 妊娠14 ~ 21周产妇尿中甲胎蛋白浓度。

Changgeng yi xue za zhi Pub Date : 1999-06-01

T T Hsieh, J J Hsu, L M Lo, J D Liou, Y K Soong

{"title":"Maternal urine alpha-fetoprotein concentrations between 14 and 21 weeks of gestation.","authors":"T T Hsieh, J J Hsu, L M Lo, J D Liou, Y K Soong","doi":"","DOIUrl":"","url":null,"abstract":"Background: The aim of this study was to ascertain the normal range of the midtrimester maternal urine alpha-fetoprotein (AFP) concentrations in Taiwanese pregnancies.Methods: AFP was measured in the urine samples, obtained before genetic amniocentesis, from 268 women with normal singleton pregnancies between 14 and 21 weeks of gestation. Week-specific median values for urine AFP/creatinine (Cr) were calculated by weighted linear regression after log transformation and the data were converted to units in the multiple of the median (MoM). The gestational age in all cases was determined by ultrasound parameters.Results: The levels of urine AFP and AFP/Cr increased gradually with advancing gestational age. The AFP/Cr MoM values of singleton pregnancies after log transformation showed a normal distribution with a mean (standard deviation) of 0.0071 (0.3228). The median, 10th and 90th centiles of AFP/Cr were 0.98, 0.43 and 3.61 MoM, respectively. Of the pregnant Taiwanese women studied, 4.9% (13/268) and 16% (43/268) had urine AFP/Cr MoM levels less than 0.31 MoM and 0.5 MoM respectively.Conclusion: The establishment of a reference range which allows for gestational differences in AFP/Cr levels is essential for further antenatal testing.","PeriodicalId":77066,"journal":{"name":"Changgeng yi xue za zhi","volume":"22 2","pages":"234-9"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21355935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endobronchial metastatic disease. 支气管内转移性疾病。

Changgeng yi xue za zhi Pub Date : 1999-06-01

Y H Wang, S L Wong, Y F Lai, A S Lin, H W Chang

{"title":"Endobronchial metastatic disease.","authors":"Y H Wang, S L Wong, Y F Lai, A S Lin, H W Chang","doi":"","DOIUrl":"","url":null,"abstract":"Background: Endobronchial metastasis (EM) is rare. Patients with EM are in advanced stages of disease and have poor prognoses. However, some patients have had long-term survival after aggressive treatment.Methods: We retrospectively reviewed the records of 9678 patients who had undergone bronchoscopic procedures. Forty patients were diagnosed as having EM.Results: The most common site of primary tumors was the head and neck [10 nasopharyngeal carcinomas (NPC), 2 buccal cancers, 2 glossal cancers, 2 laryngeal cancers]. Clinical manifestations included cough (50%), hemoptysis (20%), dyspnea (15%), and absence of respiratory symptoms (15%). The most common findings in chest roentgenograms (CXR) were single masses (40%). The median length of survival for all patients was 12 months (range, 6 to 18 months). The median length of survival in patients whose ages were over 70 years was 1 months and in patients less than 70 years old it was 12 months (range, 7 to 19 months) (p = 0.002). In patients whose EM extent was to the main bronchus, the median length of survival was 1 month (range, 1 to 3 months) and that in those whose EM did not extend to main bronchus was 12 months (range, 11 to 21 months) (p = 0.0004). In patients whose primary tumors were due to head and neck cancer other than NPC, the survival time was 1 month (range, 1 to 11 months), and in others it was 12 months (range, 7 to 19 months) (p = 0.0008).Conclusion: Three factors contributed to a poor prognosis, including the patient's age being over 70 years, primary tumors due to head and neck cancer other than NPC, and extension of the endobronchial metastatic lesion to the main bronchus.","PeriodicalId":77066,"journal":{"name":"Changgeng yi xue za zhi","volume":"22 2","pages":"240-5"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21355936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic measurement of metabolic function in the rat liver: an application of reverse microdialysis. 大鼠肝脏代谢功能的动态测量:反向微透析的应用。

Changgeng yi xue za zhi Pub Date : 1999-06-01

M H Shyr, H M Chen, P P Lu, P P Tan

{"title":"Dynamic measurement of metabolic function in the rat liver: an application of reverse microdialysis.","authors":"M H Shyr, H M Chen, P P Lu, P P Tan","doi":"","DOIUrl":"","url":null,"abstract":"Background: Traditional markers of liver function and microsomal activity tests require regular samplings and tissue removal. The microdialysis technique is a promising tool for pharmacokinetic study without the need for actually removing samples of those tissues and fluids. We verified the possibility of using reverse microdialysis for dynamic monitoring of hepatic metabolic function.Methods: Adult male Sprague-Dawley rats were used and anesthetized using pentobarbital sodium. Reverse microdialysis was done by implanting a microdialysis probe into the middle lobe of the liver; the probe was then perfused with a lidocaine-containing solution. Concentrations of lidocaine and its major metabolite, monoethylglycinexylidide (MEGX), were measured in the dialysate. Metabolic ability was assessed by dividing the MEGX production by lidocaine administration. Hepatic ischemia-reperfusion and liver cirrhosis models were used to verify its application in dynamic measurement of liver metabolic function.Results: The implantable microdialysis probe had stable contact with the liver tissue. In normal rats, 4.73 +/- 0.41% of the lidocaine was transformed to MEGX in 20 min. Only 16% of this value was preserved in cirrhotic animals. Hepatic ischemia for 20 min transiently depressed the MEGX formation and did not cause further injury after reperfusion.Conclusion: We confirmed the ability of an implantable microdialysis probe to be in constant contact with the liver tissue and thus deliver a stable transmission of chemicals across a microdialysis membrane for a certain period of time. We also verified the feasibility of reverse microdialysis as a tool for the dynamic measurement of hepatic metabolic function.","PeriodicalId":77066,"journal":{"name":"Changgeng yi xue za zhi","volume":"22 2","pages":"246-52"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21355937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vulvovaginal reconstruction following radical tumor resection: report of 12 cases. 肿瘤根治后外阴阴道重建12例报告。

Changgeng yi xue za zhi Pub Date : 1999-06-01

Y L Lai, C J Chang

{"title":"Vulvovaginal reconstruction following radical tumor resection: report of 12 cases.","authors":"Y L Lai, C J Chang","doi":"","DOIUrl":"","url":null,"abstract":"Background: The absence of the vulva and vagina is a distressful problem, especially for the sexual life of a woman. The potential benefit associated with the use of various vaginal reconstructive methods was studied.Methods: Between April 1987, and June 1997, 12 patients undergoing gynecologic carcinoma surgery were treated with simultaneous vulvovaginal reconstruction using local labia majora flaps (1), gracilis myocutaneous flaps (3), and innervated pudendal-thigh flaps (8).Results: The mean follow-up period was 32 months. There were no major surgical complications, with the exception of one patient who had a ureteroileal fistula after bilateral gracilis myocutaneous flap reconstruction and radiotherapy. One patient received pelvic radiation after bilateral gracilis myocutaneous flap reconstruction, and the complication of perineal bleeding occurred 90 days after the vaginal reconstruction. Another patient had introital stenosis of the neovagina after reconstruction using bilateral labia majora flaps. Seven patients had regular and satisfactory sexual lives. These patients were all treated by innervated pudendal-thigh flap reconstruction.Conclusion: The innervated pudendal-thigh flap provides a sensitized flap for reconstruction of the vulva and vagina following vulvovaginal carcinoma surgery. For extended carcinoma with vulvovaginal involvement, the gracilis myocutaneous flap is would be better for reconstruction of a large defect.","PeriodicalId":77066,"journal":{"name":"Changgeng yi xue za zhi","volume":"22 2","pages":"253-8"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21355938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intussusception in a child infected with enterovirus: case report. 儿童肠病毒感染肠套叠1例报告。

Changgeng yi xue za zhi Pub Date : 1999-06-01

S L Lin, S R Shih, Y B Hung, C Y Lin, C S Lu

{"title":"Intussusception in a child infected with enterovirus: case report.","authors":"S L Lin, S R Shih, Y B Hung, C Y Lin, C S Lu","doi":"","DOIUrl":"","url":null,"abstract":"Most intussusceptions in childhood are idiopathic. The association of viral infection has been suspected for decades. We report a case of ileocolonic intussusception in a child during a course of enterovirus infection. A 20-month-old girl with vomiting and irritable crying of 4 days' duration was found to have intussusception by sonography. She had suffered from herpangina one week earlier. Due to her peritoneal signs, she underwent surgical manual reduction. A cluster of enlarged lymph nodes in the intussuscipiens was noted preoperatively by high resolution ultrasound. Two swollen lymph nodes were removed for pathologic evaluation and examined for a viral genome by polymerase chain reaction (PCR) amplification. Panenterovirus base pairs were confirmed on the electrophoresis print. During postoperative sonographic follow-up, significant shrinkage of previous mesenteric lymphoid hyperplasia was observed. In this article, we present the first case of childhood intussusception in associated with enterovirus infection, in which the panenterovirus genome was identified in the patient's mesenteric lymph nodes. This was also the first evaluation of the role of mesenteric lymph nodes in intussusception by high resolution sonography.","PeriodicalId":77066,"journal":{"name":"Changgeng yi xue za zhi","volume":"22 2","pages":"319-23"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21356424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vaginoscopy using hysteroscope for diagnosis of vaginal bleeding during childhood: case report. 阴道镜应用宫腔镜诊断儿童期阴道出血1例。

Changgeng yi xue za zhi Pub Date : 1999-06-01

L T Shui, C L Lee, C F Yen, C J Wang, Y K Soong

引用次数: 0

Cerebral sparganosis: case report. 脑性斯巴达病1例。

Changgeng yi xue za zhi Pub Date : 1999-06-01

T Y Tan, C C Lui, H J Chen, C W Liou

{"title":"Cerebral sparganosis: case report.","authors":"T Y Tan, C C Lui, H J Chen, C W Liou","doi":"","DOIUrl":"","url":null,"abstract":"A 19-year-old man visited our hospital following an attack of general tonic-clonic convulsion. Multiple lesions were noted over bilateral frontal areas on brain computed tomography and magnetic resonance images. The diagnosis was confirmed by positive antibody for sparganum using enzyme-linked immunosorbent assay (ELISA). Praziquantel, 2400 mg/d for one month, was prescribed before the antibody test results came out and the treatment failed. Total removal of the lesion and the enclosed parasite cured the patient. Although the features of cerebral sparganosis on brain computed tomography and magnetic resonance images have been previously described, the findings were not specific and the present case exhibited some different patterns including bilateral multiple calcifications and ventricular compression. The significance of the bilateral involvement is not known but the ventricular compression suggests that the disease was in an active stage. Imaging studies appear to only provide some clues for the diagnosis of sparganosis. Bilateral involvement may be seen as in the present case. The final diagnosis depends on pathologic or immunologic examination results. Surgical intervention either using stereotactic techniques or total removal of the lesion is the treatment of choice while antiparasitic agents are ineffective.","PeriodicalId":77066,"journal":{"name":"Changgeng yi xue za zhi","volume":"22 2","pages":"287-92"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21357048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of department sub-division on hospital performance. 科室细分对医院绩效的影响。

Changgeng yi xue za zhi Pub Date : 1999-06-01

L Y Huang, C L Li

{"title":"The impact of department sub-division on hospital performance.","authors":"L Y Huang, C L Li","doi":"","DOIUrl":"","url":null,"abstract":"Background: Chang Gung Memorial Hospital is the first hospital in Taiwan to adopt the 'sub-division management'. The hospital sub-divided extensively growing departments into two or more similar sub-divisions. This study compared the relative performance before and after the implementation of \"sub-division management\".Methods: The cardiac department of Chang Gung Memorial Hospital was subdivided into Cardiac I and Cardiac II in July 1992. This study collected the managerial information of cardiac inpatients from 1991 through 1993 in Chang Gung Memorial Hospital. By exploring the effects of the \"sub-division management\" and other confounding factors, we tried to find out the possible impact they brought to hospital performance.Results: Considering a time trend effect, the results of regression indicate that 'sub-division' mechanism had little effect on departmental performance. However, the performance is different between Cardiac I and Cardiac II in the aspect of total expenditure per admission, average length of stay, and average number of discharge per physician. These differences might be affected by the characteristics of physicians' sub-specialties rather than the implementation of sub-division management.Conclusion: The significant decrease in mortality rate of patients in the cardiology department after the implementation might suggest that the quality of care in the cardiology department increased after the introduction of sub-divisions. The long-term effects of practice behavior induced by competition within and between sub-divisions require further organizational and behavioral studies.","PeriodicalId":77066,"journal":{"name":"Changgeng yi xue za zhi","volume":"22 2","pages":"171-80"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21356040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0