Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)最新文献

{"title":"[Effect of systematic vaccination on the epidemiology of urlian parotiditis in the population of Bucharest].","authors":"Niculae Ion-Nedelcu,&nbsp;Corina Iordăchescu,&nbsp;Rodica Mihailovici,&nbsp;Patricia Gherasim,&nbsp;Ruxanda Dumitrache-Marian,&nbsp;Cornelia Dragomirescu,&nbsp;Cristina Moculescu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>describe the mumps evolution during the time period that immediately followed the introduction of routine mumps vaccine into the Bucharest municipality's population.</p><p><strong>Methods: </strong>observational, descriptive, and retrospective study. The temporal frequencies were taken from official reports of clinically confirmed mumps cases with annually sequence during the 1951-2001 period and monthly sequence during the 2002-2009 period of time respectively. The temporal frequencies were graphically represented in semilogarithmic scale; the temporal trend of the frequencies was estimated through linear regression.</p><p><strong>Results: </strong>in the time period of 5 years subsequently to the introduction of mumps routine vaccination with two doses of measles-mumps-rubella triple vaccine, the following events intervened in the evolution of mumps in the population of Bucharest municipality: (a) starting with the year of 2006 the annual frequency of cases became constantly placed under the lower limit of 1000 cases of the prevaccine era's distribution, (b) starting with September 2005 the monthly frequency of mumps cases decreased under the lower limit of 100 cases of the prevaccine era's distribution, (c) the decline rhythm of the annual frequency account for 1156 units (r2 = 0.76; p = 0.03) and, (d) due to the herd protection effect induced by vaccine, decreasing affected all age groups.</p><p><strong>Conclusions: </strong>although late implemented (in European context) the routine vaccination determined a fairly consistent declining of the mumps morbidity and very probably of the serious complications and/or sequels associated to natural disease, being in this way an outstanding achievement of preventive medicine</p>","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"35-9"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Tuberculosis and BCG vaccination].","authors":"Irina Pele,&nbsp;Maria Dede,&nbsp;Daniela Piţigoi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"55-9"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Viable non-culturable bacteria].","authors":"Alexandra-Maria Năşcuţiu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Viable but non-culturable cells (VBNC) are defined as live bacteria, but which do not either grow or divide. Such bacteria cannot be cultivated on conventional media (they do not form colonies on solid media, they do not change broth appearance), but their existence can be proved using other methods. The switch to the VBNC stage has been described and documented for several bacterial species: Vibrio spp. (cholerae, vulnificus and other species), Escherichia coli (including EHEC), Campylobacter jejuni, Helicobacter pylori, Salmonella spp., Listeria monocytogenes, Yersinia enterocolytica, Shigella spp., Klebsiella spp., Enterobacter spp., Cronobacter spp., Staphylococcus aureus, Providencia spp., Morganella spp., Pseudomonas spp., Mycobacterium tuberculosis, Enterococcus spp. The capacity of both Gram-positive and Gram-negative bacteria to enter the VBNC stage started to concern microbiologists in the field of food industry (food and water safety) and pharmaceutical industry. Many studies have shown that processes meant to achieve bactericidal effects can favour bacterial switch to VBNC. Viable but non-culturable stage is reversible. Concerns are due to the capacity of VBNC, especially of potentially pathogen cells, to switch to the infectious stage once in the host organism.</p>","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"11-8"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Squamous cell carcinoma secondary to Buruli ulcer: a clinical case report in a young girl.","authors":"K Kassi,&nbsp;K Kouame,&nbsp;W Allen,&nbsp;L A Kouassi,&nbsp;W Ance,&nbsp;J M Kanga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Buruli Ulcer, a common tropical disease, is endemic in West Africa in particular in Cote d'Ivoire, where it represents the second mycobacterial disease after Tuberculosis. The late diagnosis and treatment as well as, the lack of surveillance, lead to large skin ulcerations, local or multifocal osteomylitis and some time it may lead to neoplasia which contribute to worse the prognosis of the patient. We presented a case report in a girl of 16 years old, who died from an aggressive squamous cell carcinoma of the upper limb secondary to Buruli Ulcer. This case report showed the importance of early detection and treatment, a specific surveillance for Buruli Ulcer infected patients, a need for them to be vigilant and to report any suspected skin lesions even after healing, and the need for a good prevention strategy in Buruli Ulcer endemic areas.</p>","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"25-8"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29431489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Aflatoxins--health risk factors].","authors":"Nicoleta Manuela Miliţă,&nbsp;Gr Mihăescu,&nbsp;Carmen Chifiriuc","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Aflatoxins are secondary metabolites produced by a group of strains, mainly Aspergillus and Penicillium species. These mycotoxins are bifurano-coumarin derivatives group with four major products B1, B2, G1 and G2 according to blue or green fluorescence emitted in ultraviolet light and according to chromatographic separation. After metabolism of aflatoxin B1 and B2 in the mammalian body, result two metabolites M1 and M2 as hydroxylated derivatives of the parent compound. Aflatoxins have high carcinogenic potential, the most powerful carcinogens in different species of animals and humans. International Agency for Research on Cancer has classified aflatoxin B1 in Group I carcinogens. The target organ for aflatoxins is the liver. In chronic poisoning, aflatoxin is a risk to health, for a long term causing cancer (hepatocellular carcinoma), and in acute intoxications aflatoxin is lethal. This work purpose to discuss aflatoxins issue: the synthesis, absorption and elimination of aflatoxins, the toxicity mechanisms, and measures to limit the content of aflatoxins in food</p>","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"19-24"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Risk of hospital death in nosocomial infection with multi-drug resistant A. baumanii or P. aeruginosa].","authors":"Niculae Ion-Nedelcu,&nbsp;Katia Lambru,&nbsp;Radu Luminiţa,&nbsp;Cornelia Manta","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>assessment of the in hospital death among the patients with healthcare associated infection (HA1) provoked by multi drug resistant strains (MDR) ofP. aeruginosa or A. baumanii.</p><p><strong>Methods: </strong>enrolled in the study were patients with bloodstream, surgical site and urinary tract HAI infection, reported during 2006-2009 in the ICU for adults and general surgery wards of two large teaching clinics for emergencies in Bucharest municipality. Associations between fatal outcome and relevant demographic and clinical characteristics were analyzed both through cohort and also by case-control studies.</p><p><strong>Results: </strong>in the cohort analysis both the severity of the underlying disease and also the presence of HAl with MDR strains of P. aeruginosa or A. baumanii were statistical significant (p < 0.05) and independently associated with fatal outcome; the presence of HAI with MDR strains of P. aeruginosa or A. baumanii remained significant associated with fatal outcome even after controlling of the underlying disease's severity by case-control design (Match OR: 5.89; 95% IC: 1.39-40.77; p = 0.011).</p><p><strong>Conclusions: </strong>the study's results demonstrate that the precautions to prevent the in hospital transmission of the MDR germs are pertinent because the HAI induced by these bugs is obviously associated with unfavorable clinical outcome of the patient.</p>","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Considerations in an outbreak of viral acute gastroenteritis, Cisnădie 2009].","authors":"Anca Sîrbu,&nbsp;Adriana Pistol,&nbsp;F Popovici,&nbsp;Alina Zaharia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Frequent cause of morbidity and mortality in the whole world, viral gastroenteritis represent about 80% of infectious gastroenteritis. In non-industrialised countries it mostly affects small children,while in those industrialised it represents a significant cause of morbidity in all age groups. During 30.04--17.06.2009 we registered 315 cases of gastroenteritis in Cisnădie. All age groups were concerned, but 78.9% of cases were children less than 14 years old. We registered cases belonging to the same family. The clinical forms of the disease were mild or moderate. Identification of enteroviruses (Coxsackie A9 and non-typable EVNP) in 2 stool samples and in the water sample gathered from the residual water tank of the City Hospital in Cisnadie demonstrates the enterovirus circulation. 7 cases were confirmed with rotavirus. For the rotaviral etiology could also plead the information received from the District Hospital Sibiu concerning a series of cases diagnosed with rotaviral infection in children, during the months preceding the onset of this outbreak. Regarding the transmission of the agent we excluded a hydric outbreak, the most probable transmission being the direct one.</p>","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"41-4"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Tricophyton rubrum in a case of tinea unguium phenotypic mycological diagnostic algorithm and its limits].","authors":"Mariana Constantin,&nbsp;Mia Brăileanu,&nbsp;Olguţa-Nicoleta Drăcea,&nbsp;B Marinescu,&nbsp;C Coman,&nbsp;Irina Codiţă","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Trichophyton rubrum is the most common dermatophyte isolated from human dermatophytosis. We present the mycological diagnosis algorithm and results in an onychomycosis case--tinea unguium. Biological samples have been inoculated on both usual and special culture media and incubated at both 30 degrees C and 37 degrees C for a period of fourteen days. Based on the macroscopic and microscopic characters and on the physiological and biochemical tests results, we identified a Trichophyton rubrum granular type dermatophyte. We are discussing phenotypic mycological diagnosis limits and molecular diagnostic benefits for rapid setting up of fungal therapy in order to avoid chronic mycosis and their complications.</p>","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"45-9"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The concept of bacterial species].","authors":"Ana-Maria Tănase,&nbsp;Tatiana Vassu,&nbsp;Ileana Stoica","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Prokaryotes are the most abundant living organisms and also most diverse from genetically and metabolically point of view, being responsible for the majority of biogeochemical processes playing the most important role in life cycle on the planet. Considering this, there is a general agreement among taxonomists, that there is a very small number of bacterial species recognized and described today, mostly because of controversial issues concerning bacterial species concept. One of the most accepted approaches, even today, is the polyphasic taxonomy because it is based on diverse information, obtained from classic taxonomy but also from molecular level. The development of new molecular techniques, especially sequencing rRNA genes conducted to an improved concept, that we intended to evaluate in this review, and even more, to reconstruction of group specific phylogenetic tree.</p>","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"5-10"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Useful biological markers in the diagnosis of autoimmune status].","authors":"Claudia Vlad,&nbsp;Mihnea Dumitrescu,&nbsp;Luciana Nica,&nbsp;Genoveva Niţa","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Unlabelled: </strong>Immune function is essential for human beings, the severe disorders of the immune system being incompatible with survival. The immune system is perfectly organized to fulfill its essential function: to distinguish self from nonself Perfect state of immune tolerance to self components is disturbed in some cases in which the immune system no longer tolerates the self and summarizes the production of autoantibodies or autoreactive lymphocytes occurrence. The purpose of this study was the determination of biological markers in groups of patients with certain conditions, in order to establish correlations between these parameters and certain pathological events, their quantitative changes in pathological condition, their predictive value for the development of autoimmune condition and the staging process of certain diseases.</p><p><strong>Materials and methods: </strong>The study was conducted on a total of 41 patients exhibiting various underlying conditions generating immunosuppression: immunosuppressed (cirrhosis, diabetes, intubated, septicemia, LED, hepatitis, dialysis), rheumatic and emergency patients (patients with and without underlying conditions). For each patient the following parameters were determined: CRP, CIC, IgG, IgM, IgA serum complement and fibrinogen. We watched the variation of each parameter on patient groups and variation of each parameter within each group.</p><p><strong>Results and discussion: </strong>We noticed a clear correlation of elevated CRP in the group of rheumatic patients (100%), followed by immunocompromised patients (88%). Fibrinogen values were increased in rheumatic, sepsis and intubated patients and CIC levels in patients presented in emergency without underlying conditions, patients with cirrhosis and hepatitis and dialysis. All rheumatic patients had low C3 values. In terms of IgM, slightly higher values were found in the groups of patients with rheumatic disease and emergency patients,those with underlying conditions, obesity, dialysis, cirrhosis and hepatitis. IgM value was low in patients with osteoporosis. In the group of emergency patients without underlying conditions, CRP level was increased where an injury occurred, for example in patients with politraumatism, but the highest value of fibrinogen and CIC was observed in intoxicated patients, results that correlate with the fact that once formed the CIC can not be cleared from the body. In intoxicated patients C3 value correlated with high IgG value that may explain the phenomenon of cytolysis that accompanies this disease. High C3 value in patients with stroke and bleeding explain the action of anafilatoxins issued during complement system activation, functioning as potent mediators of inflammatory reactions.</p><p><strong>Conclusions: </strong>Biological markers used to assess autoimmune condition can provide useful information on physio-pathological mechanisms of self-aggression installation during various chronic or ","PeriodicalId":77026,"journal":{"name":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","volume":"55 1","pages":"51-4"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29436045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}