APMIS. Supplementum最新文献

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Growth hormone, skin and wound healing--experimental studies in the rat. 生长激素,皮肤和伤口愈合——老鼠的实验研究。
APMIS. Supplementum Pub Date : 1997-01-01
P H Jørgensen
{"title":"Growth hormone, skin and wound healing--experimental studies in the rat.","authors":"P H Jørgensen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"72 ","pages":"1-54"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20290147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avoidable cancers in the Nordic countries. Tobacco smoking. 北欧国家可避免的癌症。吸烟。
APMIS. Supplementum Pub Date : 1997-01-01
L Dreyer, J F Winther, E Pukkala, A Andersen
{"title":"Avoidable cancers in the Nordic countries. Tobacco smoking.","authors":"L Dreyer,&nbsp;J F Winther,&nbsp;E Pukkala,&nbsp;A Andersen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Active smoking is causally associated with cancers of the lung, larynx, oral cavity, pharynx, oesophagus, pancreas, renal parenchyma, renal pelvis and urinary bladder, and passive smoking appears to be causally associated with cancer of the lung. Information on smoking habits for the years 1965, 1975 and 1985 shows that more men than women in the Nordic countries were current smokers. The rates of women were stable over time and those of men were decreasing, approaching those of women. Lung cancer, in particular, is strongly associated with active smoking: by increasing the number of cigarettes smoked per day (lifelong) to 5, 10, 20 and 40 or more, the risk increases by five-, eight-, 16- and 30-fold, respectively, over that of people who have never smoked. Thus, with approximately 35% current smokers and 25% former smokers among Nordic men in 1985 and approximately 30% current smokers and 15% former smokers among Nordic women in that year, by the year 2000 10,000 cases of lung cancer (6,500 in men and 3,500 in women) will be caused by active smoking; this is equivalent to 82% of all cases of lung cancer in these populations. Another 6,000 cancers of other types (4,000 in men and 2,000 in women) are caused annually by active smoking, yielding a total of 16,000 new cases each year around the turn of the century. This implies that 14% (19% in men and 9% in women) of all incident cancers in the Nordic countries around the year 2000 will be caused by active tobacco smoking. In comparison, passive smoking is a minor cause of lung cancer, responsible for approximately 0.6% of all new cases (approximately 70 cases annually) in this area around the turn of the century.</p>","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"76 ","pages":"9-47"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20389270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avoidable cancers in the Nordic countries. Alcohol consumption. 北欧国家可避免的癌症。酒精消费。
APMIS. Supplementum Pub Date : 1997-01-01
L Dreyer, J F Winther, A Andersen, E Pukkala
{"title":"Avoidable cancers in the Nordic countries. Alcohol consumption.","authors":"L Dreyer,&nbsp;J F Winther,&nbsp;A Andersen,&nbsp;E Pukkala","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Alcohol intake is causally associated with cancers of the larynx, oral cavity, pharynx, oesophagus and liver. In all five Nordic countries, alcohol consumption increased substantially between 1965 (6.5 litres per adult per year) and 1975 (10 litres), but remained at about 10 litres between 1975 and 1985. The daily consumption of men during the period was substantially higher than that of women, and that of both men and women was higher in Denmark than in the other Nordic countries. In about 2000, an annual total of almost 1,300 cancer cases (1,000 in men and 300 in women) would be avoided if alcohol drinking were eliminated. This corresponds to about 29% of all alcohol-related cancers, i.e. in the oesophagus (37%), oral cavity and pharynx (33%), larynx (29%) and liver (15%). About 2% of all cancers in men and 1% in women in the Nordic countries around the year 2000 will be caused by the drinking habits of the respective populations.</p>","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"76 ","pages":"48-67"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20389271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avoidable cancers in the Nordic countries. Occupation. 北欧国家可避免的癌症。占领。
APMIS. Supplementum Pub Date : 1997-01-01
L Dreyer, A Andersen, E Pukkala
{"title":"Avoidable cancers in the Nordic countries. Occupation.","authors":"L Dreyer,&nbsp;A Andersen,&nbsp;E Pukkala","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A number of chemicals encountered predominantly in occupational settings have been causally linked with cancer in humans; furthermore, several industrial processes and occupations have been associated convincingly with increased rates of cancer, although the specific carcinogens remain to be identified. The tissues affected are mainly the epithelial lining of the respiratory organs (nasal cavity, paranasal sinuses, larynx and lung), and urinary tract (renal parenchyma, renal pelvis and urinary bladder), the mesothelial linings, the bone marrow and the liver. During the period 1970-84, almost 4 million people (3.7 million men and 0.2 million women) in the Nordic countries were potentially exposed to above-average levels of one or more verified industrial carcinogens. It is expected that these exposures will result in a total of about 1,900 new cases of cancer every year in the Nordic countries around the year 2000, with 1,890 among men and fewer than 25 among women. The proportions that could be avoided if industrial carcinogens were eliminated would be 70% of mesotheliomas, 20% of cancers of the nasal cavity and sinuses, 12% of lung cancers, 5% of laryngeal cancers, 2% of urinary bladder cancers, 1% of the leukaemias, and 1% of renal cancers. Overall, it is estimated that verified industrial carcinogens will account for approximately 3% of all cancers in men and less than 0.1% of all cancers in women in the Nordic countries around the year 2000. No attempt was made to estimate the potential effects of suspected carcinogens in the workplace.</p>","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"76 ","pages":"68-79"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20389272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avoidable cancers in the Nordic countries. External environment. 北欧国家可避免的癌症。外部环境。
APMIS. Supplementum Pub Date : 1997-01-01
L Dreyer, A Andersen, E Pukkala
{"title":"Avoidable cancers in the Nordic countries. External environment.","authors":"L Dreyer,&nbsp;A Andersen,&nbsp;E Pukkala","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Air pollutants arising from traffic clustering and industrial production include a number of chemical compounds that at high doses are carcinogenic in animal models and in some instances also in humans. Direct epidemiological evidence for a carcinogenic effect of air pollution in humans is, however, weak, and most of the available studies are limited by lack of adequate control of confounding factors and other methodological drawbacks. Limited evidence exists for a link between urban air pollution and lung cancer, with reported relative risks of 1.0-1.5. About one-third of the population of the Nordic countries, corresponding to 7.3 million people, lives in urban areas. If there is an excess risk associated with air pollution, the annual number of lung cancer cases around the year 2000 in the Nordic countries would range from 0 (no excess risk) to 1,800 (relative risk, 1.5). As the existence of a causal link between air pollution and cancer is not uncorroborated, measures for avoiding cancer from this source cannot be recommended.</p>","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"76 ","pages":"80-2"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20391145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avoidable cancers in the Nordic countries. Exogenous hormones. 北欧国家可避免的癌症。外源激素。
APMIS. Supplementum Pub Date : 1997-01-01
J F Winther, L Dreyer, L Tryggvadottir
{"title":"Avoidable cancers in the Nordic countries. Exogenous hormones.","authors":"J F Winther,&nbsp;L Dreyer,&nbsp;L Tryggvadottir","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The well-described influence of several aspects of reproductive life on the risk for cancer in the reproductive organs has raised concern regarding the safety of exogenous hormones, particularly since sex hormones have become one of the most widely used drugs among women in the western world. The major areas of application include oral contraception and hormone replacement therapy in women with menopausal symptoms. Since the introduction of oral contraceptives onto the Nordic market in the late 1960s, the number of users has grown steadily, to reach proportions of long-term users among women aged 15-45 years in 1985 ranging between 6% (Norway) and 19% (Sweden) and proportions of current users in 1994 ranging between 20% (Norway) and 28% (Sweden). Such data on the current and long-term use of oral contraceptives by the female populations, linked with relative estimates of adverse (cancers of the breast and uterine cervix) and beneficial effects (protection against cancers of the ovary and endometrium), indicate that 95 cases of breast cancer and 40 of cervical cancer will be caused by oral contraceptives annually around 2000 in the Nordic countries, which corresponds to 0.6% of all breast cancers and approximately 3% of all cervical cancers. The beneficial effects include an annual prevention around the year 2000 of approximately 350 cases of ovarian cancer and a similar number of endometrial cancer, for a total about 700 cancer cases annually. The prevalence of long-term users (> or = 5 years) of hormone replacement therapy among Nordic women aged 40-69 in 1995 was estimated to be 10-11%, which on the basis of an associated relative risk for breast cancer ranging from 1.2-1.5 suggests than an annual total of 260 cases of breast cancer could be avoided in the Nordic countries around the year 2000 if hormone replacement therapy were eliminated. This corresponds to 1.8% of all notified cases of breast cancer among women in these countries.</p>","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"76 ","pages":"132-40"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20391149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antigenic and genetic characterization of Legionella proteins: contributions to taxonomy, diagnosis and pathogenesis. 军团菌蛋白的抗原和遗传特征:对分类、诊断和发病机制的贡献。
APMIS. Supplementum Pub Date : 1997-01-01
J M Bangsborg
{"title":"Antigenic and genetic characterization of Legionella proteins: contributions to taxonomy, diagnosis and pathogenesis.","authors":"J M Bangsborg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"70 ","pages":"1-53"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20198352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erythromycin-resistant Staphylococcus aureus in Denmark. 丹麦的耐红霉素金黄色葡萄球菌。
APMIS. Supplementum Pub Date : 1996-01-01
H Westh
{"title":"Erythromycin-resistant Staphylococcus aureus in Denmark.","authors":"H Westh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"57 ","pages":"1-37"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19580320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IgG subclasses and chronic bacterial infection. Subclass antibodies and the clinical course of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. IgG亚类与慢性细菌感染。囊性纤维化慢性铜绿假单胞菌肺部感染的亚类抗体与临床病程。
APMIS. Supplementum Pub Date : 1996-01-01
T Pressler
{"title":"IgG subclasses and chronic bacterial infection. Subclass antibodies and the clinical course of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis.","authors":"T Pressler","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"66 ","pages":"1-41"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19933715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Humoral immune response to pneumococcal vaccination. Prevention of infections with Streptococcus pneumoniae by immunization. 肺炎球菌疫苗的体液免疫反应。通过免疫预防肺炎链球菌感染。
APMIS. Supplementum Pub Date : 1996-01-01
H B Konradsen
{"title":"Humoral immune response to pneumococcal vaccination. Prevention of infections with Streptococcus pneumoniae by immunization.","authors":"H B Konradsen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77006,"journal":{"name":"APMIS. Supplementum","volume":"60 ","pages":"1-28"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19736566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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