{"title":"Patient-Centered Medicine","authors":"","doi":"10.32388/kfcob4","DOIUrl":"https://doi.org/10.32388/kfcob4","url":null,"abstract":"","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69633580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer chemotherapy.","authors":"G. Secchi","doi":"10.1201/b13234-61","DOIUrl":"https://doi.org/10.1201/b13234-61","url":null,"abstract":"(1) In June 2006 the French National Cancer Institute published the results of a survey of eating difficulties among 1843 patients receiving cancer chemotherapy; (2) More than one-third of patients said they had less appetite than before (\"far less\" in 13% of cases). About half of patients said they had noticed a change in their sensation of thirst; (3) Half of patients who had been receiving treatment for at least 6 months said they had lost weight; (4) Half of patients found food tasted different. 43% of patients found certain odours unbearable, especially perfumes and tobacco. One-third of patients said the smell of the treatment room made them nauseous. Many patients found mealtimes unpleasant, sometimes even a source of anxiety; (5) In practice, these eating difficulties should be taken into account when assessing the risk-benefit balance of cancer treatments. When a treatment needs to be pursued, patients should be helped to find ways of making food more palatable, the treatment room should be well ventilated, and perfumes should not be used.","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 1","pages":"159-60"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65977040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bactericidal/permeability-increasing protein antineutrophil cytoplasmic antibodies (ANCA) and associated diseases: clinical relevance of an emerging ANCA target antigen.","authors":"Lorenzo Emmi, Alexia Chatzipetrou","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 4","pages":"205-8"},"PeriodicalIF":0.0,"publicationDate":"2005-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25969743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Quarta, Addolorata Corrado, Nadia Melillo, Francesco Paolo Cantatore
{"title":"Juvenile idiopathic arthritis: an update on clinical and therapeutic approaches.","authors":"Laura Quarta, Addolorata Corrado, Nadia Melillo, Francesco Paolo Cantatore","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Juvenile idiopathic arthritis represents a heterogeneous group of autoimmune diseases. It arises before 16 years of age and lasts more than 6 months. We can distinguish many arthritis sub-types. A serious problem in juvenile idiopathic arthritis is skeletal growth retardation, osteopenia and greater risk of developing fractures. Juvenile idiopathic arthritis diagnosis is an exclusion diagnosis. Many conditions can simulate it. First-choice drugs in juvenile idiopathic arthritis treatment are nonsteroidal anti-inflammatory drugs, analgesic and antipyretic drugs. The second-choice drugs are \"slow-acting\" antirheumatic drugs, like methotrexate. The use of glucocorticoids is strongly influenced by their side effects, in particular the inhibition of statural growth and the premature appearance of osteoporosis. Recent findings on the central role of tumor necrosis factor-alpha, in particular damage pathogenesis in the course of juvenile idiopathic arthritis, have permitted the development of new therapeutic strategies (infliximab, etanercept), aimed at blocking this cytokine.</p>","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 4","pages":"211-7"},"PeriodicalIF":0.0,"publicationDate":"2005-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25969744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fabio Lugoboni, Gianluca Quaglio, Paolo Mezzelani, Alessandro Lechi
{"title":"[Depression in patients with cardiovascular disease].","authors":"Fabio Lugoboni, Gianluca Quaglio, Paolo Mezzelani, Alessandro Lechi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cardiovascular disease and depression, which is frequently encountered in developed countries, are unexpectedly linked and someway interdependent. Although it has been proven that major depression is a risk factor for cardiovascular disease, it is also true that cardiovascular disease may often cause depression. This article provides epidemiological data regarding this phenomenon and focuses on the mechanisms and causes that link these apparently unrelated pathologies. The diagnosis of depression and the difficulty in recognizing it as such are reviewed and several tests useful for this purpose are presented. Finally, the most common antidepressants particularly suitable for cardiac patients are examined along with any possible interactions between these drugs and those currently used for treatment of cardiovascular disease.</p>","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 4","pages":"224-32"},"PeriodicalIF":0.0,"publicationDate":"2005-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25970232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maddalena Giannella, Eleonora Pistella, Antonio Perciaccante, Mario Venditti
{"title":"Soft tissue infection caused by Mycobacterium chelonae following a liposculpture and lipofilling procedure.","authors":"Maddalena Giannella, Eleonora Pistella, Antonio Perciaccante, Mario Venditti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Skin and soft tissue infections that usually follow minor traumatic events or surgical procedures are caused by a wide spectrum of bacteria. We describe a soft tissue infection caused by a Mycobacterium chelonae in an immunocompetent patient who underwent liposculpture and lipofilling of the gluteal-trochanteric region, emphasizing the importance of clinical suspicion and effective treatment of infection.</p>","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 4","pages":"245-7"},"PeriodicalIF":0.0,"publicationDate":"2005-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25970234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Bronchiectasis worsening by p-ANCA (bactericidal/permeability-increasing protein) positive vasculitis. A case report and review of the literature].","authors":"Maurizio Benucci, Gabriele Nenci, Gianni Taccetti, Aurelio Rosso, Chiara Beltrame, Carlo Cappelletti, Mariangela Manfredi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 67-year-old woman was hospitalized with recurrent fever, arthralgia and erythema of the arms and legs. She had suffered from bronchiectasis for the previous 4 years, and Pseudomonas was persistently detected in her sputum. During the course of her illness, she developed distal sensitive and motor polyneuropathy. Serum test was positive for myeloperoxidase and bactericidal/permeability-increasing protein antineutrophil cytoplasmic antibodies. Nerve biopsy showed vasculitis infiltration of the vasa nervorum. She started immunoglobulin therapy, and after methylprednisolone and pulse cyclophosphamide therapy once monthly for 6 months she showed a good response and a reduction in symptoms.</p>","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 4","pages":"258-61"},"PeriodicalIF":0.0,"publicationDate":"2005-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25970239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Antiphospholipid syndrome and venous thromboembolism: the role of congenital thrombophilia].","authors":"Daniela Poli, Gian Franco Gensini","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The antiphospholipid syndrome is associated with complications of pregnancy or venous or arterial thrombosis in the presence of antiphospholipid antibodies. Venous thromboembolism is the most common clinical feature. Pathogenetic mechanisms underlying the syndrome are not completely understood and several hypotheses have been raised. Secondary prophylaxis after venous thromboembolism episodes requires oral anticoagulants (prothrombin time-international normalized ratio 2-3) for 6 to 12 months. More intensive anticoagulant regimens are indicated in case of recurrence. A longer or life-long course of treatment is indicated in patients with recurrent or life-threatening events or in the presence of high titers of antiphospholipid antibodies. Among risk factors for venous thromboembolism, inherited thrombophilia is recently described, such as defects of the physiological coagulation inhibitors, genetic mutations of factor V and factor II of the coagulation cascade and hyperhomocysteinemia. High levels of factor VIII, factor IX and lipoprotein(a) have recently been proposed as new risk factors for venous thromboembolism. The coexistence of inherited thrombophilia seems to enhance the thrombogenic risk, in particular in the venous vascular bed. The new insights into the diagnosis of inherited thrombophilia could allow a better evaluation of the thrombotic risk, leading to tailor the prophylactic strategy.</p>","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 4","pages":"218-23"},"PeriodicalIF":0.0,"publicationDate":"2005-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25970231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hospital care for frail, complex elders: more than a matter of appropriateness.","authors":"Mauro Di Bari, Giulio Masotti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 4","pages":"209-10"},"PeriodicalIF":0.0,"publicationDate":"2005-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25969745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Angela Becchi, Francesco Bellelli, Marco Clarizio, Nicola Carulli
{"title":"[Characteristics of patients admitted to a Division of Internal Medicine. Is hospital the best setting of care?].","authors":"Maria Angela Becchi, Francesco Bellelli, Marco Clarizio, Nicola Carulli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this study was to describe the characteristics of institutionalized patients, the patterns of admission, hospital stay and discharge and the extent of resource utilization before, during and after hospitalization, in an Acute Division of Internal Medicine of a university hospital. All adult patients admitted to the division were consecutively enrolled during a 3-month study period. Patients underwent a multidimensional assessment and data collection concerning admission and discharge patterns, resource utilization, and discharge diagnosis. Three hundred and eighteen patients, with an average age of 73.8 years, entered in the study; the rate of patients both affected by severe cognitive and functional impairment was high (29.9%); 3-4 comorbidity classes were estimated in 70.8% of patients; the most frequent diagnoses at discharge were gastrointestinal (major diagnostic category 6), liver and pancreas diseases (major diagnostic category 7); despite the high rate of comorbidity and severity of illness, the average diagnosis-related groups was low (1.15 +/- 0.59) and also the levels of nursing and personal care provided in the hospital were low (21 +/- 15 and 19 +/- 16, respectively). Median length of stay was 9 days and 3-4 comorbidity classes significantly prolonged hospitalization (p < 0.01). The main critical aspects concerning hospital admissions were the low rates of general practitioner requests of admission (26.7%), the high rates of unplanned readmissions (17.9%) and inappropriate recovery (12.6%). Concerning discharge, only 18.5% of patients had assisted discharges despite the high rates of patients with functional impairment; difficulties at discharge were estimated in 15.0% of patients. Our data suggest to improve the relation between hospital and primary health services in order to assure appropriateness of patient care and optimal use of a specialistic division.</p>","PeriodicalId":77002,"journal":{"name":"Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna","volume":"20 4","pages":"233-44"},"PeriodicalIF":0.0,"publicationDate":"2005-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25970233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}