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AIDS clinical review最新文献

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Risk of human immunodeficiency virus infection in health care workers. 卫生保健工作者感染人类免疫缺陷病毒的风险。
AIDS clinical review Pub Date : 2000-01-01
R Fahrner
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引用次数: 0
Salvage therapy for patients failing their current antiretroviral regimen. 目前抗逆转录病毒治疗失败的患者的救助疗法。
AIDS clinical review Pub Date : 2000-01-01
M A Albrecht
{"title":"Salvage therapy for patients failing their current antiretroviral regimen.","authors":"M A Albrecht","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"139-91"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21831531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel strategies toward the development of an effective vaccine to prevent human immunodeficiency virus infection or acquired immunodeficiency virus. 开发预防人类免疫缺陷病毒感染或获得性免疫缺陷病毒的有效疫苗的新策略。
AIDS clinical review Pub Date : 2000-01-01
B Ensoli, A Cafaro
{"title":"Novel strategies toward the development of an effective vaccine to prevent human immunodeficiency virus infection or acquired immunodeficiency virus.","authors":"B Ensoli, A Cafaro","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"23-61"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21831525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric human immunodeficiency virus type 1 infection: updates on prevention and management. 儿童人类免疫缺陷病毒1型感染:预防和管理的最新进展。
AIDS clinical review Pub Date : 2000-01-01
A J Melvin, L M Frenkel
{"title":"Pediatric human immunodeficiency virus type 1 infection: updates on prevention and management.","authors":"A J Melvin,&nbsp;L M Frenkel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A greater understanding of perinatal HIV-1 transmission has resulted in a marked decrease in the incidence of pediatric HIV-1 infection in several affluent nations. Advances in treatment have led to a decrease in HIV-1-related morbidity and mortality in some HIV-1-infected children. Studies are ongoing to determine methods to sustain the salutary effects of treatment. A goal of child advocates is to translate these advances to communities with few resources. Efforts are underway to make infant chemoprophylaxis widely available and to define strategies to reduce exposure to maternal virus. Likewise, there is the need to increase the access of children to treatment.</p>","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"63-83"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21831533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human immunodeficiency virus and hepatitis B and C coinfection: pathogenic interactions, natural history, and therapy. 人类免疫缺陷病毒与乙型和丙型肝炎合并感染:致病性相互作用、自然史和治疗。
AIDS clinical review Pub Date : 2000-01-01
A Y Kim, R T Chung, B Polsky
{"title":"Human immunodeficiency virus and hepatitis B and C coinfection: pathogenic interactions, natural history, and therapy.","authors":"A Y Kim,&nbsp;R T Chung,&nbsp;B Polsky","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"263-306"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21832656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rationale for immune-based therapies for human immunodeficiency virus type 1 infection. 人类免疫缺陷病毒1型感染的免疫疗法的基本原理。
AIDS clinical review Pub Date : 2000-01-01
M M Lederman, H Valdez
{"title":"Rationale for immune-based therapies for human immunodeficiency virus type 1 infection.","authors":"M M Lederman,&nbsp;H Valdez","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"229-61"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21832660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can immune responses to human immunodeficiency virus be preserved, enhanced, or restored? 对人类免疫缺陷病毒的免疫反应是否可以保存、增强或恢复?
AIDS clinical review Pub Date : 2000-01-01
B D Walker
{"title":"Can immune responses to human immunodeficiency virus be preserved, enhanced, or restored?","authors":"B D Walker","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"101-14"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21831526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug interactions of antiretroviral agents. 抗逆转录病毒药物的相互作用。
AIDS clinical review Pub Date : 2000-01-01
B W Kosel, F Aweeka
{"title":"Drug interactions of antiretroviral agents.","authors":"B W Kosel,&nbsp;F Aweeka","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"193-227"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21831530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human immunodeficiency virus prevention: applying the lessons learned. 预防人体免疫缺陷病毒:应用所吸取的经验教训。
AIDS clinical review Pub Date : 2000-01-01
T J Coates, A A Ehrhardt, D D Celentano
{"title":"Human immunodeficiency virus prevention: applying the lessons learned.","authors":"T J Coates,&nbsp;A A Ehrhardt,&nbsp;D D Celentano","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"1-22"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21831524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconstitution of immunity against opportunistic infections in the era of potent antiretroviral therapy. 在强效抗逆转录病毒治疗时代对机会性感染的免疫重建。
AIDS clinical review Pub Date : 2000-01-01
J A Aberg
{"title":"Reconstitution of immunity against opportunistic infections in the era of potent antiretroviral therapy.","authors":"J A Aberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Critical questions remain unanswered regarding the safety and efficacy of withdrawing primary and secondary prophylaxis in the context of HAART-associated immune reconstitution. What are the mediators of first phase cellular increases? Will continued HIV suppression result in continued immune restoration? And what are the immunological consequences of viral rebound despite HAART in patients whose CD4 counts remain elevated? Can immunity, once lost, be restored by reintroduction of antigens such as by tetanus or pneumococcal vaccination? Can immunoassays predict who will relapse or reactivate an OI? Is it possible to eradicate infections such as MAC, cryptococcosis, and histoplasmosis? Certainly, one can never eradicate CMV infection but can immunoassays predict who will have disease-reactivate? Unfortunately, various studies have reported contradicting results regarding the immunological response in vitro to specific antigens. Until these immunoassays become standardized and validated, it is unclear if immunoassays will be predictive of who would be at risk of development of disease or relapse. Therefore, until such time, clinicians may want to initiate and maintain primary prophylaxis in HIV-infected individuals as recommended by the USPHS/IDSA guidelines based on the nadir CD4+ T-cell count at least until studies have clearly demonstrated whether the increased CD4+ T-cell response attributed to HAART does in fact confer protection against these pathogens. Although for some OIs it does appear safe to withdraw primary prophylaxis and probably secondary prophylaxis, the decision to stop prophylaxis or maintenance therapy should be a joint decision by the patient and clinician based on the risks and benefits of stopping the therapy and the availability of close clinical monitoring for evidence of disease.</p>","PeriodicalId":76985,"journal":{"name":"AIDS clinical review","volume":" ","pages":"115-38"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21832653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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