{"title":"Sudden death due to bilateral spontaneous pneumothorax caused by rupture of congenital lung cysts.","authors":"K Simonsen","doi":"10.1007/BF01263043","DOIUrl":"https://doi.org/10.1007/BF01263043","url":null,"abstract":"<p><p>A case of sudden death of a 35-year-old woman due to spontaneous bilateral pneumothorax from rupture of congenital lung cysts is reported. The woman had been attended by two doctors before the lethal outcome. The medicolegal aspects pertaining to medical negligence, the diagnostic difficulties and the rare occurrence of the condition are discussed, as is the autopsy procedure.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 5","pages":"379-83"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01263043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13504968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gc in bloodstains.","authors":"S Rand, B Tillmann, B Brinkmann","doi":"10.1007/BF01263153","DOIUrl":"https://doi.org/10.1007/BF01263153","url":null,"abstract":"<p><p>Gc-subtyping was carried out on blood stains that had been made on cotton and glass and stored under a variety of conditions ranging from -20 degrees to +56 degrees C. The limits of detection ranged from 2 weeks at 56 degrees C up to 92 weeks at +4 degrees C and greater than 116 weeks at -20 degrees C. Additional bands that have been reported in other studies could not be detected during this study, and this difference is thought to be due to storage of the samples in the liquid state.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 6","pages":"453-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01263153","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13524868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Minakata, O Suzuki, T Kumazawa, M Asano, N Harada
{"title":"Determination of diquat in biological materials by electron spin resonance spectroscopy.","authors":"K Minakata, O Suzuki, T Kumazawa, M Asano, N Harada","doi":"10.1007/BF01261425","DOIUrl":"https://doi.org/10.1007/BF01261425","url":null,"abstract":"<p><p>An electron spin resonance (ESR) method already in use for the quantitative analysis of paraquat was applied to the analysis of diquat in blood, serum, urine, tissue homogenates and several drinks without purification of the samples. The diquat radical produced with ascorbic acid at alkaline pH was much more stable than that produced with the commonly used sodium dithionite. Radical decay in solutions covered with n-hexane was less than 5% after 60 min over a wide range of ascorbic acid concentrations. In 0.2 N NaOH solution 85% of the radicals was present even after 24 h. The limit of detection was 0.3 micrograms/ml and the required amount of sample was 0.1 ml. When both diquat and paraquat were present in a sample the diquat was first extracted with 1-butanol prior to the ESR measurement, because both species were converted to the radicals.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 8","pages":"599-607"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01261425","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13330139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rapid and sensitive identification of human blood by an ELISA-ABC method using a biotinylated antibody against human HbA0.","authors":"K Tokiwa, H Niitsu, M Tajima, S Katsura","doi":"10.1007/BF01263037","DOIUrl":"https://doi.org/10.1007/BF01263037","url":null,"abstract":"<p><p>A direct enzyme-linked immunosorbent assay (ELISA) using an avidin-biotin complex (ABC) system for the identification of human blood is described. In this ELISA-ABC method, in which biotin-labeled goat IgG antibody against human HbA0 was used, it was possible clearly to distinguish human blood from the blood of other species, including that of Japanese monkeys. It took about 3 h to obtain the results. Human Hb concentrations ranging from 22 ng to 169 micrograms produced a positive reaction, and the minimum detection limit in terms of the highest possible dilution of human blood was 1:640,000.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 5","pages":"329-34"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01263037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13344781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sudden death of a young asthmatic patient--allergic granulomatous angiitis (Churg-Strauss syndrome)].","authors":"W Tributsch, W Rabl, E Ambach, F Fend","doi":"10.1007/BF01263044","DOIUrl":"https://doi.org/10.1007/BF01263044","url":null,"abstract":"<p><p>Churg-Strauss syndrome has three main criterions: 1) severe asthma with fever attacks, 2) extra- and intravascular granulomatous proliferations of epitheloid and giant cells, 3) inflammatory infiltrates rich in eosinophilic leukocytes. All these features were given in the case of a 19-year-old woman, who died suddenly. This paper deals with the morphological findings of the forensic autopsy.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 5","pages":"385-91"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01263044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13505685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Püschel, F Mohsenian, R Bornemann, F Bschor, V Schneider, R Penning, W Spann, J von Karger, B Madea, D Metter
{"title":"[HIV-1 prevalence in deaths caused by drug overdose in various large cities of West Germany and West Berlin between 1985 and 1988].","authors":"K Püschel, F Mohsenian, R Bornemann, F Bschor, V Schneider, R Penning, W Spann, J von Karger, B Madea, D Metter","doi":"10.1007/BF01263149","DOIUrl":"https://doi.org/10.1007/BF01263149","url":null,"abstract":"<p><p>The development of the HIV-1-prevalence among drug deaths (n = 753) in several German cities (West Berlin, Frankfurt, Munich, Hamburg, Bremen, Cologne and Stuttgart) from 1985 to 1988 was evaluated; in 1988 43% of 674 deceased drug addicts were examined. The regional prevalence rate was between 15 and 25%; only in Berlin 42% of the drug deaths were HIV-infected (cumulated data of all cities over the 4-year-period: 26%). There was no uniform or steady regional development of HIV-1-prevalence in the different cities. The ratio men/women among drug deaths was 3:1. The HIV-1-prevalence among males was 22%, among females 40%. HIV-infected individuals were 2-3 years older than seronegatives. Predictions concerning the trend of prevalence rates are not possible up to now. Continuous monitoring of the HIV-status of drug deaths seems to be a worthful method to evaluate the spread of this disease among the risk group of intravenous drug addicts.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 6","pages":"407-14"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01263149","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13524864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The extent of aspartic acid racemization in dentin: a possible method for a more accurate determination of age at death?","authors":"S Ritz, H W Schütz, B Schwarzer","doi":"10.1007/BF01263154","DOIUrl":"https://doi.org/10.1007/BF01263154","url":null,"abstract":"<p><p>In the current study the objective was to find to what extent a reliable determination of age at death is made possible by establishing the degree of aspartic acid racemization in the dentin of teeth. The results of the investigation of 46 teeth are in agreement with the values found by other authors. The method presented makes a reproducible and accurate estimation of age possible. We intend to elaborate and improve this promising method for determination of age at death. The relevant points are presented here.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 6","pages":"457-62"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01263154","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13524869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Genetically-induced variability of alcohol metabolism and its effect on drinking behavior and predisposition to alcoholism].","authors":"R Eckey, D P Agarwal, H W Goedde","doi":"10.1007/BF00207339","DOIUrl":"https://doi.org/10.1007/BF00207339","url":null,"abstract":"<p><p>Alcoholism is one of the most challenging current health problems in the Western countries with far-reaching medical, social, and economic consequences. There are a series of factors that interact in predisposing or protecting an individual against alcoholism and alcohol-related disorders. This article surveys the state of our knowledge concerning the biochemical and genetic variations in alcohol metabolism and their implications in alcohol sensitivity, alcohol drinking habits, and alcoholism in different racial/ethnic groups. The major pathway for the degradation of ethanol is its oxidation to hydrogen and acetaldehyde--to which many of the toxic effects of ethanol can be attributed. Variations in alcohol and acetaldehyde metabolism via genetically determined polymorphisms in alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) seem to play an important role in individual and racial differences in acute and chronic reactions to alcohol, alcohol drinking habits, as well as vulnerability to organ damage after chronic alcohol abuse. Alcohol sensitivity and associated discomfort symptoms accompanying alcohol ingestion may be determinental for the significantly low incidence of alcoholism among the Japanese, Chinese and other Orientals of Mongoloid origin. An abnormal ALDH isozyme has been found to be widely prevalent among individuals of the Mongoloid race and is mainly responsible for the acute sensitivity to alcohol commonly observed in this race. Persons sensitive to alcohol by virtue of their genetically controlled ALDH isozyme deficiency may be discouraged from drinking large amounts of alcohol in their daily life due to the initial adverse reaction experienced after drinking alcohol. Indeed, a significantly low incidence of the mitochondrial ALDH isozyme deficiency has been observed in alcoholics as compared to psychiatric patients, drug dependents and healthy controls in Japan. How far any variation in ADH and/or ALDH activity among individuals of Caucasian origin will have similar effects has yet to be studied.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 3","pages":"169-90"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00207339","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13555522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Thyroglobulin content of the blood in cases of hanging].","authors":"E Müller, C Erfurt, W G Franke","doi":"10.1007/BF01263041","DOIUrl":"https://doi.org/10.1007/BF01263041","url":null,"abstract":"<p><p>Thyroglobulin (Tg) was determined in serum of heart blood from the bodies of 24 people who had died by hanging. In contrast to cases of sudden death (Tg 22.7 +/- 13.5 ng/ml) the Tg values varied over a wide range (from 12 to more than 400 ng/ml). The highest concentrations were observed in cases of incomplete suspension, e.g. hanging in a sitting or semi-reclining posture. We conclude that the duration of the death agony has an influence on the Tg level in serum. Except of diseases of the thyroid gland (carcinoma, adenoma) a high level of Tg in serum may be a helpful adjunct in the diagnosis of mechanical forces to the neck region inflicted before death.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 5","pages":"361-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01263041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13504967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Postmortem behavior of the rheobase].","authors":"B Madea, C Henssge","doi":"10.1007/BF01263152","DOIUrl":"https://doi.org/10.1007/BF01263152","url":null,"abstract":"<p><p>Own investigations on the postmortem rise of muscular threshold were conducted on 20 bodies with exactly known time of death. Muscular contraction was objectified using a sensitive force transducer. The muscle was excitated using rectangular impulses of 1 second duration of a current intensity which produces a force of muscular contraction of 2.5 mN. These excitations were continued over the postmortem interval until a current intensity of 80 mN doesn't cause a contraction of 2.5 mN any more. Investigations were mainly performed at the thenar muscles. There is a linear relationship between ln of muscular threshold (current intensity) and the time since death (r = 0.965). For any case the linear regression line between ln of muscular threshold and time since death was calculated. With mean values for slope and intercept the time of death was calculated for each measured threshold. Extrapolation of the time since death with mean values also for the slope reveals a much more precise estimation of the time since death than an extrapolation with an individual slope as proposed by Joachim and Feldmann (1980). The method was proved on a random sample of 8 practical cases. The real time since death was always within the 95%-limits of confidence of the extrapolated time since death.</p>","PeriodicalId":76860,"journal":{"name":"Zeitschrift fur Rechtsmedizin. Journal of legal medicine","volume":"103 6","pages":"435-52"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01263152","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13524867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}