Veterinary pathology. Supplement最新文献

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Mycotic infections of the alimentary tract of nonhuman primates: a review. 非人类灵长类动物消化道真菌感染的研究进展。
Veterinary pathology. Supplement Pub Date : 1982-09-01
G Migaki, R E Schmidt, J D Toft, A F Kaufmann
{"title":"Mycotic infections of the alimentary tract of nonhuman primates: a review.","authors":"G Migaki,&nbsp;R E Schmidt,&nbsp;J D Toft,&nbsp;A F Kaufmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lesions of candidiasis, mucormycosis (phycomycosis), entomophthoramycosis, geotrichosis, cryptococcosis, paracoccidioidomycosis and coccidioidomycosis have been reported in the alimentary tract of nonhuman primates. Candidiasis and mucormycosis were reported most often. Both Old and New World monkeys and great apes are susceptible; infection is rare in prosimians. Ulcers and necrosis of the mucosa of the alimentary tract are the principal gross lesions. A granulomatous inflammatory process occurs in which the fungi are visible histologically on hematoxylin and eosin (HE)-stained sections, but they are seen and characterized better when stained with periodic acid-Schiff (PAS) or Gomori methenamine silver (GMS) techniques. Cultural or immunofluorescence studies, or both, are necessary for specific identification of the fungi. Immunosuppression is suggested as a predisposing factor in certain mycotic diseases.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"7 ","pages":"93-103"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17867861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinicopathological studies of gastrointestinal disease in macaques. 猕猴胃肠疾病的临床病理研究。
Veterinary pathology. Supplement Pub Date : 1982-09-01
C A Holmberg, R Leininger, E Wheeldon, D Slater, R Henrickson, J Anderson
{"title":"Clinicopathological studies of gastrointestinal disease in macaques.","authors":"C A Holmberg,&nbsp;R Leininger,&nbsp;E Wheeldon,&nbsp;D Slater,&nbsp;R Henrickson,&nbsp;J Anderson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Evaluation of mortality during a two-year period at a primate colony indicated that 34% of nonexperimental deaths in macaques one year of age and older were due to gastrointestinal disease. Of deaths related to gastrointestinal disease, 12% had acute gastric dilatation, 18% had shigellosis, 12% had nontuberculous mycobacterial disease, and 58% were of undetermined cause. Histologic evaluation of the alimentary tract indicated that the large intestine was the most common site of anatomical change in monkeys that had diarrhea at the time of death. Monkeys that had a single terminal episode of diarrhea had less gastric inflammatory lesions than those that had multiple episodes of diarrhea in the last year of life.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"7 ","pages":"163-70"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18010362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enteric viruses of nonhuman primates. 非人类灵长类动物的肠道病毒。
Veterinary pathology. Supplement Pub Date : 1982-09-01
S S Kalter
{"title":"Enteric viruses of nonhuman primates.","authors":"S S Kalter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The phylogenetic relationship of nonhuman primates to man implies that many of these animals could serve as surrogates for studies of diseases of man. Many nonhuman primate species are susceptible not only to viruses of human origin but also to nonhuman primate viruses that are counterparts of viruses of man. All monkeys and great apes do not respond similarly to an antigenic stimulus. Some agents are highly pathogenic for one species and completely innocuous for another. For example, poliovirus causes disease and fatalities in great apes, but picornaviruses given orally cause few lesions in most nonhuman primates. Other enteroviruses (coxsackie-, echoviruses) have caused disease in nonhuman primates. It is difficult to separate viruses into distinct categories according to their anatomic affinities. Many viruses not considered to be enteric may be recovered from the intestinal tract. Adenoviruses, both human and nonhuman strains, which are not considered enteric viruses, nonetheless are recovered frequently from the intestinal tract. Adult animals show little evidence of disease, with the possible exception of diarrhea, after adenovirus infection. Newborns, however, may respond with a fatal pneumoenteritis. Adenovirus may be associated with diseases in organs other than the intestines. The reoviruses, which may be recovered from the intestinal tract, also are generally innocuous. Rotaviruses as pathogens in nonhuman primates are presently under study, and it is suspected that rotaviruses of man may produce experimental disease in nonhuman primates. Production of diabetes by several of the enteric viruses has been suggested but not demonstrated conclusively.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"19 Suppl 7 ","pages":"33-43"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17218342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insular amyloidosis in spontaneously diabetic nonhuman primates. 非人类灵长类动物自发性糖尿病的胰岛淀粉样变。
Veterinary pathology. Supplement Pub Date : 1982-09-01
J L Palotay, C F Howard
{"title":"Insular amyloidosis in spontaneously diabetic nonhuman primates.","authors":"J L Palotay,&nbsp;C F Howard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sections of pancreas from 21 nonhuman primates with diabetes mellitus were examined by light and electron microscopy. All monkeys showed amyloid accumulation in the islets of Langerhans. Amyloid was identified by its dichroism with three different stains: Congo red, changing from red to yellowish-green; standardized toluidine blue, changing from blue to red; and sulfated alcian blue, changing from blue-green to pink. Sulfated alcian blue was a rapid and effective means of detecting amyloid. The characteristic fibrillar structure of amyloid was seen with transmission electron microscopy. Deposition of islet amyloid was independent of the presence or absence of amyloid in other organs. Results indicate that nonhuman primates offer a model for studying the sequential development of insular amyloidotic diabetes mellitus.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"7 ","pages":"181-92"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17808388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A survey of pancreatic lesions in nonhuman primates. 非人类灵长类动物胰腺病变的调查。
Veterinary pathology. Supplement Pub Date : 1982-09-01
H M McClure, F W Chandler
{"title":"A survey of pancreatic lesions in nonhuman primates.","authors":"H M McClure,&nbsp;F W Chandler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Approximately 3,000 microslides of hematoxylin and eosin (HE)-stained sections of pancreas from 1,000 nonhuman primates were reviewed. Sections were from 557 females and 443 males; 658 were adults of unknown age and 342 were laboratory-born animals of known age. The latter included 94 animals less than one year old, 92 from one to five years old, and 156 from five to more than 20 years old. There were 326 squirrel monkeys, 319 rhesus monkeys, 100 great apes, 123 other macaques, 61 other Old World monkeys, 39 other New World monkeys, and 32 prosimians. Pancreatic lesions of varied severity found in 187 (18.7%) of these nonhuman primates included focal parenchymal or periductal accumulations of mononuclear inflammatory cells with varied degrees of periductal fibrosis in 77; hyalinized islets (amyloidosis) in 29; acute or chronic diffuse pancreatitis in 18; chronic focal pancreatitis with or without ductal hyperplasia in ten; neoplasms in 11; hemorrhage of the parenchyma or islets in eight; parasites in seven; lymphoid or ectopic splenic nodules of the parenchyma in six; acinar ectasia in six; focal parenchymal fat in six; ectopic pancreas in four; parenchymal cysts without fibrosis in three; acinar cell atrophy in one; and cystic fibrosis-like changes in one.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"7 ","pages":"193-209"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17868008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mucosal microhernias in the nonhuman primate colon: their role in the pathogenesis of colonic disease. 非人灵长类动物结肠粘膜微疝:它们在结肠疾病发病机制中的作用。
Veterinary pathology. Supplement Pub Date : 1982-09-01
G B Scott
{"title":"Mucosal microhernias in the nonhuman primate colon: their role in the pathogenesis of colonic disease.","authors":"G B Scott","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Microhernias of colonic mucosal glands through the muscularis mucosae are common in human and nonhuman primate colons, and are related to submucosal lymphoid nodules. In nonhuman primates they have been shown to play an important role in the spread of inflammatory diseases from the lamina propria to the submucosa by allowing the infective agents to pass through the muscularis mucosae. The lymphoid tissue of the alimentary tract is composed predominantly of B lymphocytes and produces humoral antibodies. This property of the lymphoid component of these microhernias may thus play a significant role in determining which infective colonic diseases penetrate into the submucosa and which remain largely confined to the lamina propria.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"19 Suppl 7 ","pages":"134-40"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17219350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An analysis of the association of gastroenteric lesions with chronic wasting syndrome of marmosets. 狨猴慢性消耗综合征与胃肠道病变的关系分析。
Veterinary pathology. Supplement Pub Date : 1982-09-01
L V Chalifoux, R T Bronson, A Escajadillo, S McKenna
{"title":"An analysis of the association of gastroenteric lesions with chronic wasting syndrome of marmosets.","authors":"L V Chalifoux,&nbsp;R T Bronson,&nbsp;A Escajadillo,&nbsp;S McKenna","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Retrospective pathology data from necropsies of 162 marmosets, Saguinus oedipus, were studied to determine the nature of chronic wasting syndrome, a poorly defined entity associated with a high mortality rate in many marmoset colonies. Paraffin sections of the gastroenteric organs of 116 of these marmosets were re-examined in detail; lesions were identified, quantitated, and analyzed with a method of multiple chi-square testing for possible associations between findings. Five distinct disease entities were identified: prosthenorchosis, amebiasis, paramyxovirus disease, sepsis, and chronic colitis. Lesions of several of these often occurred in the same monkey, and all but the first were associated with cachexia. Lesions of chronic colitis were crypt abscesses, mononuclear and polymorphonuclear infiltration of the lamina propria, epithelial cell atypia, karyorrhexis, and lymphoid hyperplasia. The cause of chronic colitis was not identified, nor was any explanation found for weight loss and increased susceptibility to disease.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"19 Suppl 7 ","pages":"141-62"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17219351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The pathoparasitology of the alimentary tract and pancreas of nonhuman primates: a review. 非人灵长类动物消化道和胰腺的病理寄生虫学研究进展。
Veterinary pathology. Supplement Pub Date : 1982-09-01
J D Toft
{"title":"The pathoparasitology of the alimentary tract and pancreas of nonhuman primates: a review.","authors":"J D Toft","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A review of the literature concerning the gross and histologic lesions associated with protozoal and metazoal parasitism in the alimentary tract and pancreas of nonhuman primates is presented. In addition, the natural history, morphology, life cycle, methods for diagnosis, and potential for zoonotic disease are reviewed briefly for each parasite discussed. The parasite species reviewed in detail are those most common or most likely to produce lesions in the alimentary tract and pancreas of the nonhuman primate host. All parasites, both pathogenic and nonpathogenic, in each major group (protozoa: flagellates, sarcodines, sporozoans, neosporans, and ciliates; and metazoa: trematodes, cestodes, nematodes, acanthocephalans, and pentastomids) that have been reported in the nonhuman primate alimentary tract and pancreas are presented in tables.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"7 ","pages":"44-92"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17867860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early colonic lesions in experimental Shigella infection in rhesus monkeys: revisited. 恒河猴实验性志贺氏菌感染的早期结肠病变:再访。
Veterinary pathology. Supplement Pub Date : 1982-09-01
A Takeuchi
{"title":"Early colonic lesions in experimental Shigella infection in rhesus monkeys: revisited.","authors":"A Takeuchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rhesus monkeys (Macaca mulatta), given 3 X 10(8) to 5 X 10(10) Shigella flexneri 2a orally, developed signs of acute shigellosis within 24 hours. A diffuse acute colitis was well established at 48 hours. The inflammatory reaction was confined to the mucosa. The submucosa showed only edema. The shigellae were found predominantly in the columnar cells of the surface epithelium, less frequently in those of the crypt, and least frequently in the lamina propria. Shigella bacilli invaded the columnar cells from the intestinal lumen. The bacilli multiplied within epithelial cells and spread laterally to adjacent epithelial cells and penetrated the lamina propria. The bacterial invasion affected epithelial cells unevenly and resulted in the disappearance of goblet cells and pyknotic shrinkage of the surface epithelial cells. Epithelial cells had abnormal and accelerated exfoliation which resulted in multifocal epithelial defects. There was a distinct correlation between the quantity of bacilli present in tissues and the intensity of the inflammatory response. The small intestines were spared.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"7 ","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17808387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An analysis of the association of gastroenteric lesions with chronic wasting syndrome of marmosets. 狨猴慢性消耗综合征与胃肠道病变的关系分析。
Veterinary pathology. Supplement Pub Date : 1982-09-01
L V Chalifoux, R T Bronson, A Escajadillo, S McKenna
{"title":"An analysis of the association of gastroenteric lesions with chronic wasting syndrome of marmosets.","authors":"L V Chalifoux,&nbsp;R T Bronson,&nbsp;A Escajadillo,&nbsp;S McKenna","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Retrospective pathology data from necropsies of 162 marmosets, Saguinus oedipus, were studied to determine the nature of chronic wasting syndrome, a poorly defined entity associated with a high mortality rate in many marmoset colonies. Paraffin sections of the gastroenteric organs of 116 of these marmosets were re-examined in detail; lesions were identified, quantitated, and analyzed with a method of multiple chi-square testing for possible associations between findings. Five distinct disease entities were identified: prosthenorchosis, amebiasis, paramyxovirus disease, sepsis, and chronic colitis. Lesions of several of these often occurred in the same monkey, and all but the first were associated with cachexia. Lesions of chronic colitis were crypt abscesses, mononuclear and polymorphonuclear infiltration of the lamina propria, epithelial cell atypia, karyorrhexis, and lymphoid hyperplasia. The cause of chronic colitis was not identified, nor was any explanation found for weight loss and increased susceptibility to disease.</p>","PeriodicalId":76797,"journal":{"name":"Veterinary pathology. Supplement","volume":"7 ","pages":"141-62"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17868007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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