Upsala journal of medical sciences. Supplement最新文献_第5页

Eicosanoids and the central nervous system. 类二十烷酸和中枢神经系统。

Upsala journal of medical sciences. Supplement Pub Date : 1990-01-01

C Galli, A Petroni

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Vulnerability of developing brain to undernutrition. 发育中的大脑容易营养不良。

Upsala journal of medical sciences. Supplement Pub Date : 1990-01-01

J L Smart

{"title":"Vulnerability of developing brain to undernutrition.","authors":"J L Smart","doi":"","DOIUrl":"","url":null,"abstract":"Four questions are addressed: - 1. What are the immediate effects of undernutrition on developing brain likely to be and what are they? 2. Can any general statement be made about vulnerability of developing brain to undernutrition? 3. To what extent are the immediate effects recoverable on refeeding? 4. Do any attenuating or compensatory mechanisms operate? 1. IMMEDIATE EFFECTS: It is worth stating what is almost axiomatic, because it is often forgotten, that undernutrition is likely to affect only those processes which are contemporaneous with it (plus some that follow it). This is borne out by the available evidence. There appears to be little or no destruction of existing structures by undernutrition. 2. GENERAL STATEMENT ON IMMEDIATE EFFECTS: The novel general statement is examined that undernutrition affects the growth rate of all processes contemporaneous with it to the same extent. This is found to have considerable generality. The possible, though perhaps illusory exception of myelination is discussed. Uniform growth restriction gives rise to distorted brain growth through interaction of the timing of different brain growth processes with the timing of undernutrition. 3. EXTENT OF RECOVERY: Recovery is considered in terms of true catch-up: diminution in absolute deficit. The extent of recovery on refeeding varies from none, through partial, to complete, depending on the process under consideration and the timing and severity of the undernutrition. 4. POSSIBLE COMPENSATORY MECHANISMS: Intrinsic to the animal include altered cell cycle characteristics, delayed development, that all of these operate to a greater or lesser extent, during or after undernutrition, thus reducing the magnitude of effects and facilitating recovery.","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"48 ","pages":"21-41"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13233100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Dietary lipids and the central nervous system. A symposium. Stockholm, November 2-3, 1988. Proceedings. 膳食脂质和中枢神经系统。一个研讨会。1988年11月2日至3日，斯德哥尔摩。程序。

Upsala journal of medical sciences. Supplement Pub Date : 1990-01-01

引用次数: 0

Brain lipid changes after organic solvent exposure. 有机溶剂暴露后脑脂质的变化。

Upsala journal of medical sciences. Supplement Pub Date : 1990-01-01

T Kyrklund, K G Haglid

{"title":"Brain lipid changes after organic solvent exposure.","authors":"T Kyrklund, K G Haglid","doi":"","DOIUrl":"","url":null,"abstract":"Animals (rats, gerbils and guinea pigs) were exposed to various common solvents. The brain lipids were extracted and analysed. In particular the fatty acid pattern of a major phospholipid, ethanolamine, phosphoglyceride was studied. A major finding was that some chlorinated solvents, trichloroethylene, perchloroethylene and 1,1,1-trichloroethane, had effects on the ethanolamine phosphoglyceride fatty acid pattern, while most other solvents, like toluene, xylene, white spirit and Freon 11 lacked this effect. Relatively small, but significant, changes were observed in the proportions of the polyunsaturated fatty acids of both the n-6 and n-3 series. The selective effect of the chlorinated solvents might indicate that they have a specific effect on the enzymatic regulation of membrane fatty acid composition. However, the lack of effects of other solvents might also be explained by low blood levels, due either to a low uptake (Freon 11, white spirit) or an extensive metabolism (toluene, xylene). Intrauterine exposure of guinea pigs to perchloroethylene (160 ppm) during the last half of gestation had minor effects on the ethanolamine phosphoglyceride fatty acid pattern. Thus it appears that animals during the period of rapid brain growth are equally sensitive to exposure as adult animals.","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"48 ","pages":"267-77"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13233103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Pathology of the central nervous system with special reference to the lipids. 中枢神经系统病理学，特别与脂质有关。

Upsala journal of medical sciences. Supplement Pub Date : 1990-01-01

P Sourander

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Reference list of biomedical and clinical publications. Uppsala 1990. 生物医学和临床出版物的参考书目。1990年乌普萨拉。

Upsala journal of medical sciences. Supplement Pub Date : 1990-01-01

引用次数: 0

Biochemistry of the neurolipids. 神经脂类生物化学。

Upsala journal of medical sciences. Supplement Pub Date : 1990-01-01

L Svennerholm

引用次数: 0