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Ukrainskii biokhimicheskii zhurnal (1978)最新文献

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[Effect of contrical on proteolytic enzymes of blood serum in acute emotional-pain stress]. [中药对急性情绪疼痛应激血清蛋白水解酶的影响]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
L M Tarasenko, S V Vakulenko
{"title":"[Effect of contrical on proteolytic enzymes of blood serum in acute emotional-pain stress].","authors":"L M Tarasenko,&nbsp;S V Vakulenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>General proteolytic and antitryptic blood serum activity in acute emotionally-painful stress was investigated as well as that on the background of the before injected contrical. It was determined that in case of a stress there increases the general proteolytic activity of blood serum and at the same time antiproteolytic activity decreases. The coefficient of the relation of antiproteolytic activity to proteolytic activity of blood serum in case of a stress may become of 50% of the control. The introduction of inhibitor of proteinase contrical before the beginning of stressor influence promotes the decrease of general proteolytic activity to the level of the control indexes.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"130-4"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20756166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Activity of elastase and its inhibitors in arterial tissues and blood serum under experimental arterio-atherosclerosis]. [实验性动脉粥样硬化下动脉组织和血清中弹性蛋白酶及其抑制剂的活性]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
V Ie Dosenko
{"title":"[Activity of elastase and its inhibitors in arterial tissues and blood serum under experimental arterio-atherosclerosis].","authors":"V Ie Dosenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The role of the elastolytic system serum and arterial tissues in pathogenesis of vascular pathology was investigated on rabbits in experimental arterio-atherosclerosis. Activation of proteolytic enzymes, in particular elastase, sharp alteration capacity of inhibitors in arterial wall both at Menckeberg arteriosclerosis and atherosclerosis, permits to assume, that in the basis these different pathologic processes can lie general mechanisms, which will be realized through disturbance of the elastolytic system balance in blood vessels.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"88-94"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Inhibiting effect of the aqueous extract of Arctostaphylos uva-ursi on myrosinase activity from Brassica napus seeds]. [熊熊葡萄球菌水提物对甘蓝型油菜种子黑芥子酶活性的抑制作用]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
M S Mykytyn, Dem'ianchuk
{"title":"[Inhibiting effect of the aqueous extract of Arctostaphylos uva-ursi on myrosinase activity from Brassica napus seeds].","authors":"M S Mykytyn,&nbsp;Dem'ianchuk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The search of inhibitors of the myrosinase enzyme and also enzymes able to transform the glucosinolates into non-toxic combinations has been carried out among the water extracts of the plants row. The inhibitor activity of the water extract of Arctostaphylos uva-ursi and its foresee acting outset-hydroquinone have been discovered. The direct dependence of the glucosinolates decompose degree from concentration of hydroquinone and quinone has been determined. The cultivation of Brassica napus cut seeds by quinone in correlation 1:100 (m:m) stopped the glucosinolates decomposition by endogenous myrosinase for 50%.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"122-6"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Relationship between the oxidation-reduction system of astrocytes with production of active forms of oxygen]. [星形胶质细胞氧化还原系统与活性氧产生的关系]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
G N Semenkova, Z B Kvacheva, S V Obydennikova, S N Cherenkevich, L P Titov
{"title":"[Relationship between the oxidation-reduction system of astrocytes with production of active forms of oxygen].","authors":"G N Semenkova,&nbsp;Z B Kvacheva,&nbsp;S V Obydennikova,&nbsp;S N Cherenkevich,&nbsp;L P Titov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cells of neuroglia--the astrocytes are of interest from the point of view of their participation in phagocytosis. Phagocyte ability to generate active oxygen forms (AOF) as used as the basic criterion of the estimation of their functional activity. For the purpose to clear up molecular and cellular mechanisms of phagocytosis a study of astrocyte redox-systems, participating in production of AOF, was undertaken. Registration of AOF in astrocytes was carried out using a method of luminol-dependent chemiluminescence. Primary culture of guinea pig astrocytes was used. Spontaneous chemiluminescence of low intensity was found for the astrocytes at the presence of luminol. The destruction of the cells was accompanied by a significant growth of the intensity of spontaneous chemiluminescence. Suspension of endocutosis inductors, particle of latex and phytohemagglutinin, added to astrocytes did not result in formation of AOF, characteristic for other cells, possessing phagocytosis. It was established, that addition of hydrogen peroxide destroys astrocytes at the presence of luminol and gives rise to the emission. Chemiluminescence was not observed in similar experiments with intact cells. A conclusion was made that inside astrocytes there are structures, which show peroxidase-like activity.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"126-30"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Changes in lipid metabolism during oxidative stress caused by cobalt chloride injection]. 【注射氯化钴引起氧化应激时脂质代谢的变化】。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
R V Shalamov, A L Zagaĭko
{"title":"[Changes in lipid metabolism during oxidative stress caused by cobalt chloride injection].","authors":"R V Shalamov,&nbsp;A L Zagaĭko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The cobalt chloride influence on rat liver and serum blood lipids and lipoproteins content and composition was investigated. The data obtained show that the cobalt chloride injection leads to the oxidative stress development and to activation of lipid transport and metabolism. It has been shown that there is system of lipids homeostasis in the organism and it is activated under conditions of oxidative stress. The system blood lipoproteins and liver lipoproteins was found to participate in metabolism adaptation on oxidative stress and in maintenance of biological membranes structure and functioning.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"68-79"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antiradical activity and membranotropic action of cardio- and vasotropic compounds of varying chemical nature]. [不同化学性质的促心脏和血管化合物的抗自由基活性和膜性作用]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
I V Nizhenkovskaia, Iu I Gubskiĭ, I S Checkman, A G Goriushko, N A Gorchakova, L G Sachenko
{"title":"[Antiradical activity and membranotropic action of cardio- and vasotropic compounds of varying chemical nature].","authors":"I V Nizhenkovskaia,&nbsp;Iu I Gubskiĭ,&nbsp;I S Checkman,&nbsp;A G Goriushko,&nbsp;N A Gorchakova,&nbsp;L G Sachenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Antiradical activity and ability to interaction with phosphatidylcholine bilayer of the physiological active compounds (PhAC), concerning the classes of phenylalkilamines (dobutamine, verapamil), dihydro pyridines (BAY-K-4688, nifedipine), analogues of crown ether (carbicyle, diol) was studied. By means of the method of microcalorimetry and spectrophotometry it was shown the complexing ability PhAC with the phospholipid bilayer of the model membrane. It was stated the simbasity in the changes of the thermal effect of the compounds with the negative inotropic activity during its reaction with phosphatidylcholine bilayer and antiradical activity. That show on the presence of antiradical component in the mechanism that compounds' action.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"51-8"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Content of components of the renin-angiotensin-aldosterone system of blood plasma of healthy children in the early neonatal period]. [新生儿早期健康儿童血浆肾素-血管紧张素-醛固酮系统组分的含量]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
A N Voloshin, I A Komarevtseva, B A Bezkaravaĭnyĭ, A V Seredenko, G V Vernik
{"title":"[Content of components of the renin-angiotensin-aldosterone system of blood plasma of healthy children in the early neonatal period].","authors":"A N Voloshin,&nbsp;I A Komarevtseva,&nbsp;B A Bezkaravaĭnyĭ,&nbsp;A V Seredenko,&nbsp;G V Vernik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The dynamics of the renin and angiotensin converting ferment activity and of the aldosterone concentration in the plasma of blood by healthy newborn full-term in the first week of the life after the birth was determined. The normative values of the studied indexes were obtained. The researches have shown the considerable functional tension of the renin-angiotensin-aldosterone system, that has a very important signification for optimal course of adaptation and anabolic processes by the children at the very beginning of the postnatal development.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"84-8"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Formation of inositol triphosphate in lymphocytes of rat spleen in the early stages after x-irradiation]. [x射线照射后早期大鼠脾脏淋巴细胞中肌醇三磷酸的形成]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
O P Matyshevs'ka
{"title":"[Formation of inositol triphosphate in lymphocytes of rat spleen in the early stages after x-irradiation].","authors":"O P Matyshevs'ka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Stimulation of 32P-phosphoinositides turnover and phosphatidylinositol-4,5-biphosphate hydrolysis is observed 6 h after animals X-ray irradiation in a dose 1 Gy. Both mitogenic lectins LPS and PHA (10 mg/ml), but not 0.5 microM A23187 induce inositol phosphates release from endogenous [3H]inositol--phospholipids in lymphocytes. The level of inositol triphosphate is increased within 1-6 h and decreased in 12 h after irradiation. 45Ca2+ influx through lymphocytes plasma membrane is not changed within 3 h, but increases greatly 12 h after exposure. Data obtained indicate that IP3 formation is an early signal for radiation-induced changes in calcium homeostasis.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"94-100"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Delayed evaluation of urea content in bioassays using a chemical stabilizer]. [使用化学稳定剂对生物测定中尿素含量的延迟评价]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
H M Iarmol'chuk
{"title":"[Delayed evaluation of urea content in bioassays using a chemical stabilizer].","authors":"H M Iarmol'chuk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have studied 126 chemical compounds. Moreover 9-triphenylphosphoniomethyl-phenanthrene chloride has been found to stabilize bioassays and preserve their urea content unchanged for a period of 90-990 days. Due to its use a delayed technique of a quantitative assessment of urea in biological objects has been elaborated characterized by universal novelty. It may be used with the aim of studying metabolic processes in the cosmonauts' body, atomic submarine crews, members of polar, alpine, desert, underwater, space and other expeditions which cannot be accompanied by a biochemical laboratory.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"143-7"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20756170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Disorders of the processes of protein biosynthesis and a decrease in the content of cytochromes P-450 and b5 in the microsomal fraction of rat kidney in the dynamics of development of acute pyelonephritis]. [急性肾盂肾炎发生动力学中大鼠肾脏微粒体部分蛋白质生物合成过程紊乱和细胞色素P-450和b5含量降低]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01
Kh Ia Karimov, R N Akhmedov, F Kh Inoiatova
{"title":"[Disorders of the processes of protein biosynthesis and a decrease in the content of cytochromes P-450 and b5 in the microsomal fraction of rat kidney in the dynamics of development of acute pyelonephritis].","authors":"Kh Ia Karimov,&nbsp;R N Akhmedov,&nbsp;F Kh Inoiatova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Noticeable decrease in microsomal protein level MOS terminal component--cytochrome P-450 and MOS median link--cytochrome b5 contents in microsomal fraction implicated in renal pathologic process was established in development of acute unilateral pyelonephritis. These findings reduction expression directly depended on severity and pathologic process development degree. One of the main causes led to reduction in cytochromes P-450 and b5 level and inhibition proteins biosynthesis may be influence of toxic products which are generated in substance exchange involved in prevalence of catabolic processes in injured kidney and intensification in endogenous intoxication syndrome on renal structures. Implication of many other factors effecting decrease in microsomal hemoproteins and protein levels in the damaged kidney in above pathology showed necessity to perform further investigations in the field given.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"139-42"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20756173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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