The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku最新文献

Tumor induction in mice administered neonatally with N-bis(2-hydroxypropyl)nitrosamine (BHPN). 新生儿用n -双(2-羟丙基)亚硝胺(BHPN)诱导小鼠肿瘤。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1993-12-01

K Fujii, T Hayakawa, M Kikuchi

引用次数: 0

Identification of the deterministic chaos in cardiovascular dynamics by the use of the non-linear mathematics. 用非线性数学方法辨识心血管动力学中的确定性混沌。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1993-12-01

T Yambe, S Nitta, T Sonobe, S Naganuma, S Kobayashi, Y Haga, M Tanaka, T Fukuju, M Miura, N Sato

{"title":"Identification of the deterministic chaos in cardiovascular dynamics by the use of the non-linear mathematics.","authors":"T Yambe, S Nitta, T Sonobe, S Naganuma, S Kobayashi, Y Haga, M Tanaka, T Fukuju, M Miura, N Sato","doi":"","DOIUrl":"","url":null,"abstract":"Chaotic behavior in cardiovascular dynamics was thought to be one of the important information to analyze the circulatory regulatory system. Several investigators studied the attractor in the signals of the electrocardiogram, and found the strange attractor, suggesting dynamics compatible with deterministic chaos, by the use of the non-linear mathematics. It is interesting problem to analyze the hemodynamic parameters by the use of non-linear mathematics for the determination of the physiologically optimal circulatory condition. In this study, Chaos analyzing system was developed to identify the deterministic chaos in cardiovascular regulatory system by the use of the non-linear mathematics including phase plane plots, embedding, and lyapunov exponents. Time series data of the hemodynamic parameters in the chronic animal experiments was analyzed by this system, and satisfactory attractor was obtained by the use of the phase plane plots and embedding techniques. Furthermore, calculation of the lyapunov exponents showed the existence of the deterministic chaos in arterial blood pressure in the chronic animal experiments using adult goats, suggesting this tool is useful for analyzing cardiovascular dynamic behavior.","PeriodicalId":76727,"journal":{"name":"The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku","volume":"39 1-4","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18939350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systemic circulation with high frequency blood flow--analysis from neurophysiological point of view. 高频血流的体循环——从神经生理学的角度分析。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1991-12-01

T Yambe, S Nitta, Y Katahira, T Sonobe, S Naganuma, Y Kakinuma, H Akiho, M Tanaka, T Fukuju, M Miura

{"title":"Systemic circulation with high frequency blood flow--analysis from neurophysiological point of view.","authors":"T Yambe, S Nitta, Y Katahira, T Sonobe, S Naganuma, Y Kakinuma, H Akiho, M Tanaka, T Fukuju, M Miura","doi":"","DOIUrl":"","url":null,"abstract":"The vibrating electromagnetically driven univalved artificial heart, which provided more than 10 1/min at 10 Hz/sec. vibration, was developed in our team. This vibrating electromagnetic pump (VEMP) produced the original flow pattern compared with the flow pattern of the natural heart, so that circulatory regulatory system during maintain the circulation with VEMP must be investigated before the clinical application. In order to assess the effect of high frequency blood flow produced by the VEMP from the neurophysiological point of view, power spectral analysis of the hemodynamics was performed. VEMP was implanted as the total left heart bypass in adult goats and right heart circulation was maintained by natural hearts. In arterial blood pressure during maintain circulation by the high frequency blood flow, Mayer waves (0.01-0.15 Hz) were significantly decreased, though respiratory waves (0.25-0.40 Hz) were not significantly changed. These results suggest that circulatory regulatory system was influenced by the high frequency blood flow produced by the VEMP.","PeriodicalId":76727,"journal":{"name":"The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku","volume":"38 2-4","pages":"69-73"},"PeriodicalIF":0.0,"publicationDate":"1991-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13003863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sympathetic nerve activity during maintaining circulation with only left ventricular assist device. 仅用左心室辅助装置维持血液循环时交感神经活动。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1991-12-01

S Nitta, T Yambe, Y Katahira, T Sonobe, S Naganuma, Y Kakinuma, M Tanaka, M Miura, N Sato, H Mohri

{"title":"Sympathetic nerve activity during maintaining circulation with only left ventricular assist device.","authors":"S Nitta, T Yambe, Y Katahira, T Sonobe, S Naganuma, Y Kakinuma, M Tanaka, M Miura, N Sato, H Mohri","doi":"","DOIUrl":"","url":null,"abstract":"Maintaining circulation with an left ventricular assist device (LVAD) alone during cardiac arrest until heart transplantation, was evaluated by the use of the sympathetic neurogram. To evaluate the influences of this method on autonomic nervous system, sympathetic neurogram was analyzed by power spectrum and coherence function. In acute animal experiments using mongrel dogs, LVAD were implanted. After the LVAD implantation, ventricular fibrillation was induced electrically. Renal sympathetic nerve activity (RSNA) was detected by the use of bipolar electrodes attached to the left renal sympathetic nerve. Values of squared coherence between the arterial pulse wave and RSNA were calculated. Under the condition of circulatory maintenance with LVAD, coherence at the cardiac rhythm frequency was decreased, and coherence at the LVAD pumping rhythm frequency was increased. These results suggest that the arterial pressure which was observed during maintaining the circulation with only LVAD contributed to sympathetic neurogram.","PeriodicalId":76727,"journal":{"name":"The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku","volume":"38 2-4","pages":"51-6"},"PeriodicalIF":0.0,"publicationDate":"1991-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13003859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Echo-guided transaortic left ventricular myotomy for idiopathic hypertrophic subaortic stenosis. 超声引导下经主动脉左心室肌切开术治疗特发性肥厚性主动脉下狭窄。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1991-12-01

S Nitta, T Yambe, K Nitta, Y Katahira, Y Saijo, T Sonobe, S Naganuma, Y Kakinuma, M Tanaka, M Miura

引用次数: 0

Long-time inflation of the PTCA balloon. PTCA气球的长期膨胀。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1991-12-01

T Yambe, S Nitta, S Chiba, Y Saijoh, S Naganuma, Y Kakinuma, M Tanaka, T Meguro, N Endoh, M Mitsuoka

引用次数: 0

Effect of respiratory phases and gravity on mucociliary transport in the normal lungs. 呼吸相和重力对正常肺粘膜纤毛运输的影响。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1991-12-01

T Isawa, T Teshima, Y Anazawa, M Miki, K Shiraishi, M Motomiya

{"title":"Effect of respiratory phases and gravity on mucociliary transport in the normal lungs.","authors":"T Isawa, T Teshima, Y Anazawa, M Miki, K Shiraishi, M Motomiya","doi":"","DOIUrl":"","url":null,"abstract":"Effect of gravity and respiratory phase on mucociliary transport was studied in 11 normal subjects. After inhaling 99mTc-human serum albumin aerosol, each subject was positioned in right lateral decubitus and then supine position before a scintillation camera. Data in list mode and simultaneous respiratory curve were stored in a computer for 15 min each. The respiratory curve was sequentially marked at the beginning of inspiration, expiration and pause of each respiratory cycle and list mode data was converted into frame mode, respectively. The frame mode data was then sequentially connected according to the respective respiratory phase. The data in count-per-second from each lungs versus time was fitted to a straight line by regression analysis and the slope of the line was compared with each other for respective respiratory phase. Slopes of net radioactivity changes in the right and left lungs were compared to evaluate gravity effect. Neither respiratory phases nor gravity had any significant effect on mucociliary transport. Theoretical calculations have also supported the present findings.","PeriodicalId":76727,"journal":{"name":"The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku","volume":"38 2-4","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"1991-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13003858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and clinical evaluation of the long time digital Holter ECG system using non-tracking technology. 采用无跟踪技术的长时间数字式动态心电图系统的研制与临床评价。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1991-12-01

S Nitta, T Yambe, Y Katahira, T Sonobe, S Naganuma, S Chiba, Y Kakinuma, M Tanaka, M Miura, N Sato

引用次数: 0

beta-Lactamase activity in sputum and indirect pathogenicity. 痰中β -内酰胺酶活性与间接致病性。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1991-12-01

A Watanabe, K Oizumi, M Motomiya

{"title":"beta-Lactamase activity in sputum and indirect pathogenicity.","authors":"A Watanabe, K Oizumi, M Motomiya","doi":"","DOIUrl":"","url":null,"abstract":"beta-Lactamase activity of sputum of 39 patients with respiratory infections and that of bacterial isolates from their sputum were determined by nitrocefin method. Forty-six microbial strains (16 different species) were recovered from 39 sputum samples. The beta-lactamase activity was negative only in nine of the 46 strains. beta-lactamase-positive strains were recovered from 35 of 39 sputum samples. Of these 35 sputum samples, the beta-lactamase activity was positive in 23 and negative in 12. beta-lactamase-negative strains were recovered from 4 of 39 sputum samples, and the beta-lactamase activity was negative in all of these four sputum samples. Both beta-lactamase producing and non-producing strains were recovered in 5 of 6 sputum samples from which two to three microbes were isolated. The ratio of beta-lactamase-positive sputum sample was higher in patients who had received antibiotics than in those who had received no antibiotics. This difference was statistically significant (P < 0.025). It is possible that non-causative beta-lactamase-positive organisms enhance the pathogenicity of causative organisms that are beta-lactamase-negative.","PeriodicalId":76727,"journal":{"name":"The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku","volume":"38 2-4","pages":"83-9"},"PeriodicalIF":0.0,"publicationDate":"1991-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13003865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrodynamic endurance test of the prosthetic valve used in the various types of the ventricular assist device. 用于各类心室辅助装置的人工瓣膜的水动力耐久性试验。

The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku Pub Date : 1991-12-01

S Nitta, T Yambe, Y Katahira, T Sonobe, Y Saijoh, S Naganuma, H Akiho, Y Kakinuma, M Tanaka, M Miura

{"title":"Hydrodynamic endurance test of the prosthetic valve used in the various types of the ventricular assist device.","authors":"S Nitta, T Yambe, Y Katahira, T Sonobe, Y Saijoh, S Naganuma, H Akiho, Y Kakinuma, M Tanaka, M Miura","doi":"","DOIUrl":"","url":null,"abstract":"To evaluate the various basic designs of the pump chambers used in the ventricular assist devices (VADs), hydrodynamic endurance test was performed from the viewpoint of the durability of the prosthetic valves used in the VAD. For the hydrodynamic analysis, we designed three basic types of pump (sac type, diaphragm type, and pusher plate type) using the same material and having the same capacity and shape. Prosthetic valves in these VADs were tested from the standpoint of the water hammer effect, which affects the valve durability, to determine which pump design would be most durable as a prosthetic valve in the VAD. The water-hammer phenomenon was evaluated using the maximum pressure gradient (MPG) across the prosthetic valve in the moc circulatory loop. Maximum pump output was recorded when we used the diaphragm type model, and minimum MPG in the commonly used driving condition of the VAD were recorded when we used the sac type model. The results suggest that the sac type VAD model is the most durable design for the prosthetic value.","PeriodicalId":76727,"journal":{"name":"The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku","volume":"38 2-4","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"1991-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13003860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0