{"title":"The role of circulating CA15-3 levels in monitoring of patients with breast cancer.","authors":"D Franchini, P Bonelli, G Gavaruzzi, G Ugolotti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"177-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tumor markers and chemotherapy.","authors":"S Francioni, M Pastore, E Castellaro","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"251-9"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Fazio, L Negri, F Calabrese, F Correggia, S Giacomasso, V Mastromatteo
{"title":"A new method for the in vitro transfer of delayed hypersensitivity by dialysed transfer factor.","authors":"M Fazio, L Negri, F Calabrese, F Correggia, S Giacomasso, V Mastromatteo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"271-4"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A De Benedetto, G G Marchei, G Cardinale, M Michetti, P Marchei, M G Reale
{"title":"[Value of the determination of urinary hydroxyproline (OH-P) in a group of patients with various neoplasms].","authors":"A De Benedetto, G G Marchei, G Cardinale, M Michetti, P Marchei, M G Reale","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"275"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Piantino, A Fusaro, A Randone, A Cerchier, E Daziano
{"title":"[Increased levels of Ca 19-9, Ca 50 and Ca 125 in patients with benign diseases of the biliary tract and the pancreas].","authors":"P Piantino, A Fusaro, A Randone, A Cerchier, E Daziano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of the present study was to examine the relationship between the \"tumor markers\" Ca 19-9, Ca 50 and Ca 195 and benign pancreatic and biliary tract diseases. We measured serum Ca 19-9, Ca 50 and Ca 195 values in 144 subjects with biliary tree diseases (47), chronic pancreatitis (87), and acute pancreatitis (10). Practically all patients with acute cholangitis (20) had marked elevations of serum values of examined markers. Also in acute pancreatitis Ca 19-9, Ca 50 and Ca 195 shows a large number of fase positives (40-50 and 60% respectively). Our results indicate that serum Ca 19-9, Ca 50 and Ca 195 are markedly elevated in patients with acute cholangitis and pancreatitis. Furthermore the markers returns promptly to normal after the resolution of the acute phase of diseases. In general hiperbilirubinemia (greater than 5 mgr) is related with an important number of false positives. Much caution is needed in interpretating markedly elevated levels of serum Ca 19-9, Ca 50 and Ca 195 in patients presenting with jaundice of unclear origin.</p>","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"97-102"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13248127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G De Angelis, F De Marinis, D Bigioni, M R Migliorino, M G Alma, F Pigorini
{"title":"[Usefulness of carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), enolase (NSE) and thymidine-kinase (TK) in the monitoring and prognosis of primary carcinoma of the lung].","authors":"G De Angelis, F De Marinis, D Bigioni, M R Migliorino, M G Alma, F Pigorini","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"135-40"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13123823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Venarucci, V Venarucci, P Catalini, A Anconetani, A Vallese
{"title":"[Determination of P-170 using C-219].","authors":"D Venarucci, V Venarucci, P Catalini, A Anconetani, A Vallese","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"195-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13140847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Manna, L Trasatti, L Cifaldi, G G Marchei, M G Reale, P Marchei
{"title":"[Prostatic diseases: tumor markers (PAP and PSA) and age at risk].","authors":"A Manna, L Trasatti, L Cifaldi, G G Marchei, M G Reale, P Marchei","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"91"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G B Salabè, A Olivieri, H Salabè-Lotz, G Ravagnan, S Carta
{"title":"Monoclonal autoantibody to thyroglobulin as a possible vector in immunodiagnosis and immunotherapy of differentiated thyroid cancer.","authors":"G B Salabè, A Olivieri, H Salabè-Lotz, G Ravagnan, S Carta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Differentiated thyroid carcinoma synthetize and secrete thyroglobulin. During its biosynthesis this antigen becomes expressed in the microvilli-bearing surface of carcinoma cells. Attempts have been carried out to target, with specific antithyroglobulin antibodies, the membrane bound absorption thyroglobulin in cancer cells for in vivo diagnosis and therapy. In the serum of patients with autoimmune thyroid diseases a high concentration of antithyroglobulin antibodies is frequently found (1-3 mg/ml). Their purification by immunoabsorption and dissociation is hampered by a low recovery and partial denaturation. It has been recently reported that about 1% of sera from Hashimoto's thyroiditis bear in their electrophoretogram a \"myeloma-like protein\". In the present report we describe in the serum of a Hashimoto patient a myeloma-like IgG which is an antithyroglobulin autoantibody with restricted functional and structural properties. The serum concentration of this myeloma-like IgG was found to be 40 mg/ml with a capacity of 6.5 nM of human thyroglobulin/mg IgG. The light chain composition was determined to be mostly of the lambda type. The clonal analysis of this myeloma IgG carried out by isoelectrofocusing, immunoblotting and autoradiography resulted in the recognition of several distinct clones, two of which were prominent at pH 8.7 and 7.8. By this technique and in view of the high serum concentration of this myeloma-like IgG, single clones of antithyroglobulin autoantibody can be easily obtained in high yields and without denaturation from human serum. This reagent could offer an ideal immunovector to target membrane-bound thyroglobulin of cancer cells.</p>","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4","pages":"304-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13246257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Onetto, G B Secco, R Fardelli, G Camerini, L De Salvo, W Ventrella, R Lionetto
{"title":"CA 195 in colorectal cancer.","authors":"M Onetto, G B Secco, R Fardelli, G Camerini, L De Salvo, W Ventrella, R Lionetto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"123-6"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13246897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}