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The Journal of nuclear medicine and allied sciences最新文献

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A new method for the in vitro transfer of delayed hypersensitivity by dialysed transfer factor. 迟发性超敏反应的透析转移因子体外转移新方法。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
M Fazio, L Negri, F Calabrese, F Correggia, S Giacomasso, V Mastromatteo
{"title":"A new method for the in vitro transfer of delayed hypersensitivity by dialysed transfer factor.","authors":"M Fazio, L Negri, F Calabrese, F Correggia, S Giacomasso, V Mastromatteo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"271-4"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Value of the determination of urinary hydroxyproline (OH-P) in a group of patients with various neoplasms]. [尿羟脯氨酸(OH-P)测定在不同肿瘤患者中的价值]。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
A De Benedetto, G G Marchei, G Cardinale, M Michetti, P Marchei, M G Reale
{"title":"[Value of the determination of urinary hydroxyproline (OH-P) in a group of patients with various neoplasms].","authors":"A De Benedetto, G G Marchei, G Cardinale, M Michetti, P Marchei, M G Reale","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"275"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Increased levels of Ca 19-9, Ca 50 and Ca 125 in patients with benign diseases of the biliary tract and the pancreas]. [胆道和胰腺良性疾病患者Ca 19-9、Ca 50和Ca 125水平升高]。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
P Piantino, A Fusaro, A Randone, A Cerchier, E Daziano
{"title":"[Increased levels of Ca 19-9, Ca 50 and Ca 125 in patients with benign diseases of the biliary tract and the pancreas].","authors":"P Piantino,&nbsp;A Fusaro,&nbsp;A Randone,&nbsp;A Cerchier,&nbsp;E Daziano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of the present study was to examine the relationship between the \"tumor markers\" Ca 19-9, Ca 50 and Ca 195 and benign pancreatic and biliary tract diseases. We measured serum Ca 19-9, Ca 50 and Ca 195 values in 144 subjects with biliary tree diseases (47), chronic pancreatitis (87), and acute pancreatitis (10). Practically all patients with acute cholangitis (20) had marked elevations of serum values of examined markers. Also in acute pancreatitis Ca 19-9, Ca 50 and Ca 195 shows a large number of fase positives (40-50 and 60% respectively). Our results indicate that serum Ca 19-9, Ca 50 and Ca 195 are markedly elevated in patients with acute cholangitis and pancreatitis. Furthermore the markers returns promptly to normal after the resolution of the acute phase of diseases. In general hiperbilirubinemia (greater than 5 mgr) is related with an important number of false positives. Much caution is needed in interpretating markedly elevated levels of serum Ca 19-9, Ca 50 and Ca 195 in patients presenting with jaundice of unclear origin.</p>","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"97-102"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13248127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Determination of P-170 using C-219]. [C-219测定P-170]。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
D Venarucci, V Venarucci, P Catalini, A Anconetani, A Vallese
{"title":"[Determination of P-170 using C-219].","authors":"D Venarucci,&nbsp;V Venarucci,&nbsp;P Catalini,&nbsp;A Anconetani,&nbsp;A Vallese","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"195-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13140847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunolocalisation of testicular tumours using radiolabelled monoclonal antibody to placental alkaline phosphatase. 应用放射性标记胎盘碱性磷酸酶单克隆抗体免疫定位睾丸肿瘤。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
H P Kalofonos, C Kosmas, T R Pawlikowska, A Bamias, D Snook, B Dhokia, G B Sivolapenko, N S Courtenay-Luck, A A Epenetos
{"title":"Immunolocalisation of testicular tumours using radiolabelled monoclonal antibody to placental alkaline phosphatase.","authors":"H P Kalofonos,&nbsp;C Kosmas,&nbsp;T R Pawlikowska,&nbsp;A Bamias,&nbsp;D Snook,&nbsp;B Dhokia,&nbsp;G B Sivolapenko,&nbsp;N S Courtenay-Luck,&nbsp;A A Epenetos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tumour associated monoclonal antibody against placental alkaline phosphatase (H17E2) was radiolabelled with Indium-111 and Iodine-123 and administered intravenously in 33 patients with primary and/or metastatic testicular tumour, as well as in 8 patients who were in complete remission after surgical excision of the tumour. The presence of a tumour was confirmed and correlated well with conventional diagnostic techniques and, in addition, the antibody scan revealed the presence of active disease in 2 patients with negative conventional imaging and with elevated serum markers. In addition, in one patient the CT produced a false positive result where the antibody scan was negative. Finally, the absence of tumour was confirmed in all 8 cases of patients in complete remission. All patients studied with Indium-labelled antibody had observable concentrations of the radiolabel in the liver (estimated to be approximately 30% of the administered dose), as well as in the kidneys and spleen. The patients studied with the Iodine-123 labelled antibody had observable concentrations in the thyroid gland and the stomach. The best images were seen at 48 and 24 hrs after the Indium and Iodine radiolabelled antibody respectively. No human anti-mouse antibody was detected in any of our patients, even in those who received 2 and 3 administrations, with the highest amount of administered protein being 800 micrograms. No toxicity was encountered in any of our patients in 4 months of follow-up. This method may be of clinical value in patients with testicular neoplasma and represents a new addition to current imaging techniques. A positive scan indicates the definite presence of a tumor.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4","pages":"294-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13246351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor antigens CA 125 and CA 15-3 as markers of endometrial adenocarcinoma. 肿瘤抗原ca125和ca15 -3作为子宫内膜腺癌的标志物。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
L Babilonti, A Riccardi, S Tateo, F Pavesi, M Lotzniker, F Polatti
{"title":"Tumor antigens CA 125 and CA 15-3 as markers of endometrial adenocarcinoma.","authors":"L Babilonti,&nbsp;A Riccardi,&nbsp;S Tateo,&nbsp;F Pavesi,&nbsp;M Lotzniker,&nbsp;F Polatti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"79-83"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of circulating CA15-3 levels in monitoring of patients with breast cancer. 循环CA15-3水平在乳腺癌患者监测中的作用。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
D Franchini, P Bonelli, G Gavaruzzi, G Ugolotti
{"title":"The role of circulating CA15-3 levels in monitoring of patients with breast cancer.","authors":"D Franchini,&nbsp;P Bonelli,&nbsp;G Gavaruzzi,&nbsp;G Ugolotti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"177-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Prostatic diseases: tumor markers (PAP and PSA) and age at risk]. [前列腺疾病:肿瘤标志物(PAP和PSA)和危险年龄]。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
A Manna, L Trasatti, L Cifaldi, G G Marchei, M G Reale, P Marchei
{"title":"[Prostatic diseases: tumor markers (PAP and PSA) and age at risk].","authors":"A Manna,&nbsp;L Trasatti,&nbsp;L Cifaldi,&nbsp;G G Marchei,&nbsp;M G Reale,&nbsp;P Marchei","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"91"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The proliferation marker concept with TPS as a model. A preliminary report. 以TPS为模型的增殖标志物概念。初步报告。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
B Björklund, V Björklund
{"title":"The proliferation marker concept with TPS as a model. A preliminary report.","authors":"B Björklund,&nbsp;V Björklund","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4 Suppl","pages":"203"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoclonal autoantibody to thyroglobulin as a possible vector in immunodiagnosis and immunotherapy of differentiated thyroid cancer. 甲状腺球蛋白单克隆自身抗体作为分化型甲状腺癌免疫诊断和免疫治疗的可能载体。
The Journal of nuclear medicine and allied sciences Pub Date : 1990-10-01
G B Salabè, A Olivieri, H Salabè-Lotz, G Ravagnan, S Carta
{"title":"Monoclonal autoantibody to thyroglobulin as a possible vector in immunodiagnosis and immunotherapy of differentiated thyroid cancer.","authors":"G B Salabè,&nbsp;A Olivieri,&nbsp;H Salabè-Lotz,&nbsp;G Ravagnan,&nbsp;S Carta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Differentiated thyroid carcinoma synthetize and secrete thyroglobulin. During its biosynthesis this antigen becomes expressed in the microvilli-bearing surface of carcinoma cells. Attempts have been carried out to target, with specific antithyroglobulin antibodies, the membrane bound absorption thyroglobulin in cancer cells for in vivo diagnosis and therapy. In the serum of patients with autoimmune thyroid diseases a high concentration of antithyroglobulin antibodies is frequently found (1-3 mg/ml). Their purification by immunoabsorption and dissociation is hampered by a low recovery and partial denaturation. It has been recently reported that about 1% of sera from Hashimoto's thyroiditis bear in their electrophoretogram a \"myeloma-like protein\". In the present report we describe in the serum of a Hashimoto patient a myeloma-like IgG which is an antithyroglobulin autoantibody with restricted functional and structural properties. The serum concentration of this myeloma-like IgG was found to be 40 mg/ml with a capacity of 6.5 nM of human thyroglobulin/mg IgG. The light chain composition was determined to be mostly of the lambda type. The clonal analysis of this myeloma IgG carried out by isoelectrofocusing, immunoblotting and autoradiography resulted in the recognition of several distinct clones, two of which were prominent at pH 8.7 and 7.8. By this technique and in view of the high serum concentration of this myeloma-like IgG, single clones of antithyroglobulin autoantibody can be easily obtained in high yields and without denaturation from human serum. This reagent could offer an ideal immunovector to target membrane-bound thyroglobulin of cancer cells.</p>","PeriodicalId":76654,"journal":{"name":"The Journal of nuclear medicine and allied sciences","volume":"34 4","pages":"304-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13246257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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