The American journal of medical technology最新文献

SOS. SOS。

The American journal of medical technology Pub Date : 2018-07-24 DOI: 10.2307/j.ctvt7x67d.6

N. Hirschberg

引用次数: 0

Detection of demyelination in multiple sclerosis by analysis of [Formula: see text] relaxation at 7 T. 通过分析 7 T 下的[公式：见正文]松弛，检测多发性硬化症中的脱髓鞘现象。

IF 4.2

The American journal of medical technology Pub Date : 2015-03-04 eCollection Date: 2015-01-01 DOI: 10.1016/j.nicl.2015.02.021

Xiaozhen Li, Peter van Gelderen, Pascal Sati, Jacco A de Zwart, Daniel S Reich, Jeff H Duyn

{"title":"Detection of demyelination in multiple sclerosis by analysis of [Formula: see text] relaxation at 7 T.","authors":"Xiaozhen Li, Peter van Gelderen, Pascal Sati, Jacco A de Zwart, Daniel S Reich, Jeff H Duyn","doi":"10.1016/j.nicl.2015.02.021","DOIUrl":"10.1016/j.nicl.2015.02.021","url":null,"abstract":"Multiple sclerosis (MS) is a relatively common cause of inflammatory demyelinating lesions of the central nervous system. In an attempt to detect and characterize ongoing demyelination in MS patient brains, we used a novel magnetic resonance imaging (MRI) technique, involving the fitting of a three-component model to the [Formula: see text] relaxation behavior at high-field (7 T). This model allowed estimation of the amount of myelin water (and thus indirectly myelin content), axonal water, and interstitial water. In this study, 25 relapsing-remitting MS patients underwent a 7 T MRI from which 12 gadolinium-enhancing lesions, 61 non-enhancing lesions, and their corresponding contralateral normal appearing white matter (NAWM) regions were analyzed. In both enhancing and non-enhancing lesions, the amplitude of myelin water was significantly decreased, and interstitial and axonal water were increased relative to the contralateral NAWM. Longer relaxation time [Formula: see text] of interstitial and axonal water, and lower frequency shift of axonal water, were also observed in both enhancing and non-enhancing lesions when compared to the contralateral NAWM. No significant difference was found between enhancing lesions and non-enhancing lesions. These findings suggest that the fitting of a three-component model to the [Formula: see text] decay curve in MS lesions may help to quantify myelin loss.","PeriodicalId":76595,"journal":{"name":"The American journal of medical technology","volume":"26 1","pages":"709-714"},"PeriodicalIF":4.2,"publicationDate":"2015-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.nicl.2015.02.021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75751361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

An explanation of the terminology and definitions recommended by the Committee for Clarification of the Nomenclature of Cells and Diseases of the Blood and Blood-Forming Organs. 解释澄清血液和造血器官细胞和疾病命名委员会建议的术语和定义。

The American journal of medical technology Pub Date : 2012-09-15 DOI: 10.1542/9781581107722-ch04

M. E. Hughes

引用次数: 0

Case Study: Cystic Fibrosis 案例研究:囊性纤维化

The American journal of medical technology Pub Date : 2004-01-27 DOI: 10.1002/047146158X.CH20

S. Bolsover, J. Hyams, E. Shephard, H. A. White, C. Wiedemann

引用次数: 0

On estimating biological variation in diagnostic tests: application to the oral glucose tolerance test. 诊断试验中生物变异的估计:在口服糖耐量试验中的应用