发布求助
文献互助 智能选刊 最新文献

Texas reports on biology and medicine最新文献

筛选
英文 中文
Interferon, an antiviral drug for use in man. 干扰素，一种用于人体的抗病毒药物。
Texas reports on biology and medicine Pub Date : 1981-01-01
M Myers, G Galasso
{"title":"Interferon, an antiviral drug for use in man.","authors":"M Myers, G Galasso","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"543-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17253610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2',5'-oligoadenylate synthetase in interferon-treated chick cells. 干扰素处理的鸡细胞中的2'，5'-寡聚腺苷酸合成酶。
Texas reports on biology and medicine Pub Date : 1981-01-01
L A Ball, D K West
{"title":"2',5'-oligoadenylate synthetase in interferon-treated chick cells.","authors":"L A Ball,&nbsp;D K West","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chick embryo cells respond to interferon by producing very high levels of 2-5A synthetase. From inhibitor studies, it appears that the response involves the controlled derepression of an interferon-inducible gene. Continuous interaction of the cells with interferon seems to be necessary to maintain maximal enzyme induction. Partial purification of the synthetase indicates that it is probably composed of a single polypeptide of 56,000 MW. Upon activation by binding to dsRNA, this polypeptide catalyzes a nucleotidyl transferase reaction in which 5'-AMP residues are transferred from ATP to the 2' position of appropriate acceptors. A number of naturally occurring small molecules (in addition to 2-5A itself) that can function as adenylate acceptors have been identified, but the physiological significance of these adenylylation reactions remain to be established.</p>","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"487-92"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17253720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modulation of interferons inhibitory effect on cell growth by the mitogenic stimulus. 有丝分裂刺激对干扰素抑制细胞生长作用的调节。
Texas reports on biology and medicine Pub Date : 1981-01-01
J Taylor-Papadimitriou, E Rozengurt
{"title":"Modulation of interferons inhibitory effect on cell growth by the mitogenic stimulus.","authors":"J Taylor-Papadimitriou,&nbsp;E Rozengurt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"509-16"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17253721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospects in interferon research. 干扰素研究展望。
Texas reports on biology and medicine Pub Date : 1981-01-01
M Krim
{"title":"Prospects in interferon research.","authors":"M Krim","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"681-92"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17254610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antigenic properties of interferons. 干扰素的抗原特性。
Texas reports on biology and medicine Pub Date : 1981-01-01
C A Ogburn, B J Dalton
{"title":"Antigenic properties of interferons.","authors":"C A Ogburn,&nbsp;B J Dalton","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"23-30"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17248758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Problems in standardization: an Interferon Standards Committee report. 标准化中的问题:干扰素标准委员会报告。
Texas reports on biology and medicine Pub Date : 1981-01-01
S E Grossberg, G J Galasso
{"title":"Problems in standardization: an Interferon Standards Committee report.","authors":"S E Grossberg,&nbsp;G J Galasso","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"294-7"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17248767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of interferon on cell-mediated immunity. 干扰素对细胞免疫的影响。
Texas reports on biology and medicine Pub Date : 1981-01-01
E De Maeyer, J De Maeyer-Guignard
{"title":"Effect of interferon on cell-mediated immunity.","authors":"E De Maeyer,&nbsp;J De Maeyer-Guignard","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"420-6"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17816237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trials of interferon in respiratory infections in man. 干扰素治疗人类呼吸道感染的试验。
Texas reports on biology and medicine Pub Date : 1981-01-01
S B Greenberg, M W Harmon, D A Tyrrell, G M Scott
{"title":"Trials of interferon in respiratory infections in man.","authors":"S B Greenberg,&nbsp;M W Harmon,&nbsp;D A Tyrrell,&nbsp;G M Scott","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is not yet clear from these recent volunteer studies (8) and from the results of Merigan et al. (14) what the optimal method and schedule for administering HuIFN should be. Taken together, the results with relatively low doses of interferon (1 to 4 X 10(6) units) plus antihistamine pretreatment, and with multiple doses of HuIFN alpha (total 14 X 10(6) units) indicate the need for better methods of delivery. However, it is of interest that protection was achieved by extremely small amounts of HuIFN alpha protein - Merigan (14) used only about 160 mcg. We anticipate that with better supplies of interferon from HuIFN genes cloned in bacteria, we may seek more efficient means of delivery and obtain better protection of volunteers against respiratory virus infections.</p>","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"549-54"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17816239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local application of interferon to malignant brain tumors. 干扰素在恶性脑肿瘤中的局部应用。
Texas reports on biology and medicine Pub Date : 1981-01-01
M Nagai, T Arai, S Kohno, M Kohase
{"title":"Local application of interferon to malignant brain tumors.","authors":"M Nagai,&nbsp;T Arai,&nbsp;S Kohno,&nbsp;M Kohase","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"693-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18099793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibitor(s) of virus replication (IVR) and localization of viruses in plants. 病毒复制抑制剂（IVR）和病毒在植物中的定位。
Texas reports on biology and medicine Pub Date : 1981-01-01
G Loebenstein, A Gera
{"title":"Inhibitor(s) of virus replication (IVR) and localization of viruses in plants.","authors":"G Loebenstein, A Gera","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A substance(s) inhibiting virus replication (IVR) is released into the medium from tobacco mosaic virus-infected protoplasts of a cultivar in which the infection in the intact plant is localized. IVR inhibited virus replication in protoplasts from both resistant (Samsun NN) and susceptible (Samsun) plants, when applied up to 18 h after inoculation. It was not produced in protoplasts from susceptible plants or from noninoculated protoplasts of the resistant cultivar. IVR was partially purified using ZnAc2 precipitation, and yielded two biologically active principles with molecular weights of about 26,000 and 56,000 daltons. Preliminary results indicate that IVR inhibits replication of TMV and several other non-related viruses when applied to inoculated leaf disks.</p>","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"213-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18359004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信