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Texas reports on biology and medicine最新文献

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Approaches to the stabilization of interferons. 稳定干扰素的方法。
Texas reports on biology and medicine Pub Date : 1981-01-01
J J Sedmak, S E Grossberg
{"title":"Approaches to the stabilization of interferons.","authors":"J J Sedmak,&nbsp;S E Grossberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Considerable effort has been expended in the past few years toward establishing an armamentarium of different techniques to stabilize naturally produced alpha-and beta-interferons, particularly the beta type in view of its greater lability. Of the techniques reported, it seems that addition of various proteins, rare earth salts, and use of acid pH conditions may be the most useful since they are relatively nontoxic and protect against both thermal and mechanical stress inactivation. Little has so far been reported on the stability of recombinant DNA-derived interferons. It is unlikely that they will be any more stable when they are purified than the natural human interferons. To generate stable preparations of these bacteria-produced interferons for clinical use it is important to establish different nontoxic techniques and approaches to prevent inactivation of these interferons during preparation, processing, concentration, purification and storage.</p>","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"274-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17869767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Purification and properties of murine interferon. 小鼠干扰素的纯化及性质研究。
Texas reports on biology and medicine Pub Date : 1981-01-01
Y Kawade
{"title":"Purification and properties of murine interferon.","authors":"Y Kawade","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"219-24"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17248759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transmission of IFN-induced activities by cell to cell communication. ifn诱导的细胞间传递。
Texas reports on biology and medicine Pub Date : 1981-01-01
J E Blalock, S Baron, H M Johnson, G J Stanton
{"title":"Transmission of IFN-induced activities by cell to cell communication.","authors":"J E Blalock,&nbsp;S Baron,&nbsp;H M Johnson,&nbsp;G J Stanton","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In conclusion, many of the activities of IFN are transmissible between cells and may involve more than one transfer mechanism. These mechanisms probably involve secondary messenger molecules which are shared with hormones and act at the transcriptional level. The transfer system seems to be a major amplification process for IFN action. It will be interesting in the future to determine the spectra of IFN activities which are transferable as well as the processes involved.</p>","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"344-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17250113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interferon-mediated changes in lipid metabolism. 干扰素介导的脂质代谢变化。
Texas reports on biology and medicine Pub Date : 1981-01-01
K A Chandrabose, P Cuatrecasas, R Pottathil
{"title":"Interferon-mediated changes in lipid metabolism.","authors":"K A Chandrabose,&nbsp;P Cuatrecasas,&nbsp;R Pottathil","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"499-508"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17253606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synergistic antiviral effects of interferon plus antibody against acute hemorrhagic conjunctivitis viruses, herpes virus and adenovirus. 干扰素加抗体对急性出血性结膜炎病毒、疱疹病毒和腺病毒的协同抗病毒作用。
Texas reports on biology and medicine Pub Date : 1981-01-01
M P Langford, G J Stanton
{"title":"Synergistic antiviral effects of interferon plus antibody against acute hemorrhagic conjunctivitis viruses, herpes virus and adenovirus.","authors":"M P Langford,&nbsp;G J Stanton","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"538-42"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17253609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antitumor effects of interferon and poly ICLC, and their possible utility as anti-neoplastic agents in man. 干扰素和聚ICLC的抗肿瘤作用及其作为抗肿瘤药物的应用前景。
Texas reports on biology and medicine Pub Date : 1981-01-01
H B Levy, A S Levine
{"title":"Antitumor effects of interferon and poly ICLC, and their possible utility as anti-neoplastic agents in man.","authors":"H B Levy,&nbsp;A S Levine","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"653-62"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17253624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cell-regulatory functions of interferon induced enzymes: antimitogenic effect of (2'-5')oligo-A, growth-related variations in (2'-5')oligo-A synthetase, and isolation of its mRNA. 干扰素诱导酶的细胞调控功能:(2’-5’)寡聚a的抗生丝作用，(2’-5’)寡聚a合成酶的生长相关变异，及其mRNA的分离。
Texas reports on biology and medicine Pub Date : 1981-01-01
M Revel, A Kimchi, M Friedman, D Wolf, G Merlin, A Panet, S Rapoport, Y Lapidot
{"title":"Cell-regulatory functions of interferon induced enzymes: antimitogenic effect of (2'-5')oligo-A, growth-related variations in (2'-5')oligo-A synthetase, and isolation of its mRNA.","authors":"M Revel,&nbsp;A Kimchi,&nbsp;M Friedman,&nbsp;D Wolf,&nbsp;G Merlin,&nbsp;A Panet,&nbsp;S Rapoport,&nbsp;Y Lapidot","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"452-62"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17253716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular mechanisms of action of interferon. 干扰素作用的分子机制。
Texas reports on biology and medicine Pub Date : 1981-01-01
C Baglioni, T W Nilsen, P A Maroney, F de Ferra
{"title":"Molecular mechanisms of action of interferon.","authors":"C Baglioni,&nbsp;T W Nilsen,&nbsp;P A Maroney,&nbsp;F de Ferra","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"471-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17253717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-interferon cellular products capable of virus inhibition. 能抑制病毒的非干扰素细胞产物。
Texas reports on biology and medicine Pub Date : 1981-01-01
S Kumar, S Baron
{"title":"Non-interferon cellular products capable of virus inhibition.","authors":"S Kumar,&nbsp;S Baron","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"395-401"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18359010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Induction of interferon by bacteria, protozoa, and viruses: defensive role. 细菌、原生动物和病毒诱导干扰素:防御作用。
Texas reports on biology and medicine Pub Date : 1981-01-01
S Baron, V Howie, M Langford, E M Macdonald, G J Stanton, J Reitmeyer, D A Weigent
{"title":"Induction of interferon by bacteria, protozoa, and viruses: defensive role.","authors":"S Baron,&nbsp;V Howie,&nbsp;M Langford,&nbsp;E M Macdonald,&nbsp;G J Stanton,&nbsp;J Reitmeyer,&nbsp;D A Weigent","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Interferon is established as one of the natural defenses against virus infection. The evidence that interferon may serve a defensive role against certain protozoa is less complete and consists mainly of induction of interferon during protozoal infection, as well as interferon protection of mice against malarial infection. The evidence that interferon may function as a defense against certain bacterial infections is extended with data indicating that a wide variety of bacteria can induce interferon in the mouse and in cultured human peripheral lymphoid cells. This induction of interferon by bacteria and the ability of interferon under many conditions to activate neutrophils and macrophages raises the possibility that interferon may serve a defensive role against some bacteria.</p>","PeriodicalId":76584,"journal":{"name":"Texas reports on biology and medicine","volume":"41 ","pages":"150-7"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17248747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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