Progress in clinical immunology最新文献

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Mimicry by Virus of Host Molecules: Implications for Autoimmune Disease 病毒对宿主分子的模仿:对自身免疫性疾病的影响
Progress in clinical immunology Pub Date : 1986-12-31 DOI: 10.1016/B978-0-12-174685-8.50079-2
M. Oldstone, P. Schwimmbeck, T. Dyrberg, R. Fujinami
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引用次数: 22
Drug-induced systemic lupus erythematosus. 药物性系统性红斑狼疮。
Progress in clinical immunology Pub Date : 1980-01-01
A Weinstein
{"title":"Drug-induced systemic lupus erythematosus.","authors":"A Weinstein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite some confusion in the literature, drug-induced SLE is a well defined reversible clinical entity. The lupus syndromes induced by procainamide, hydralazine, and isoniazid have been well studied and the data obtained have been convincing. Other drugs may also induce a lupus syndrome, but adequate prospective studies have not been done. Furthermore, many other drugs previously incriminated appear to activate spontaneous SLE rather than induce the de novo lupus syndrome. The mechanism by which procainamide, hydralazine, and isoniazid exert their effect is not known, and animal studies have been unrewarding. However, hydralazine and procainamide are capable of complexing with nuclear antigens in vitro and possibly in vivo and may evoke antinuclear antibody responses in this way. A number of defined factors influence the development of the clinical syndrome, including the cumulative drug dosage, the acetylator phenotype of the individual, and the biochemical nature of the drug. Studies to date have not revealed how these drugs induce the clinical disease. While these agents may induce antinuclear antibodies in many individuals, genetic influences may be important in determining which patients will develop clinical symptoms. Further study of drug-induced systemic lupus erythematosus is necessary in order to resolve these problems regarding pathogenesis. The resolution of these problems may shed light on the pathogenesis of spontaneous SLE.</p>","PeriodicalId":76367,"journal":{"name":"Progress in clinical immunology","volume":"4 ","pages":"1-21"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18039564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune responses of human lymphocytes in vitro. 人淋巴细胞体外免疫应答的研究。
Progress in clinical immunology Pub Date : 1980-01-01
B F Haynes, P Katz, A S Fauci
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引用次数: 0
Autoantibodies to the insulin receptor: clinical significance and experimental applications. 胰岛素受体自身抗体:临床意义及实验应用。
Progress in clinical immunology Pub Date : 1980-01-01
L C Harrison, C R Kahn
{"title":"Autoantibodies to the insulin receptor: clinical significance and experimental applications.","authors":"L C Harrison,&nbsp;C R Kahn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76367,"journal":{"name":"Progress in clinical immunology","volume":"4 ","pages":"107-25"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18039565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lymphocytotoxic antibodies. Lymphocytotoxic抗体。
Progress in clinical immunology Pub Date : 1980-01-01
R J DeHoratius
{"title":"Lymphocytotoxic antibodies.","authors":"R J DeHoratius","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76367,"journal":{"name":"Progress in clinical immunology","volume":"4 ","pages":"151-54"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18039567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospects for the clinical control of IgE synthesis. IgE合成的临床控制展望。
Progress in clinical immunology Pub Date : 1980-01-01
D H Katz
{"title":"Prospects for the clinical control of IgE synthesis.","authors":"D H Katz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76367,"journal":{"name":"Progress in clinical immunology","volume":"4 ","pages":"127-50"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18039566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation and clinical significance of circulating immune complexes. 循环免疫复合物的评价及临床意义。
Progress in clinical immunology Pub Date : 1980-01-01
A N Theofilopoulos
{"title":"Evaluation and clinical significance of circulating immune complexes.","authors":"A N Theofilopoulos","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76367,"journal":{"name":"Progress in clinical immunology","volume":"4 ","pages":"63-106"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17311326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The oxidative killing mechanisms of the neutrophil. 中性粒细胞的氧化杀伤机制。
Progress in clinical immunology Pub Date : 1977-01-01
B D Cheson, J T Curnette, B M Babior
{"title":"The oxidative killing mechanisms of the neutrophil.","authors":"B D Cheson,&nbsp;J T Curnette,&nbsp;B M Babior","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76367,"journal":{"name":"Progress in clinical immunology","volume":"3 ","pages":"1-65"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11240192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suppressor cells in the regulation of the immune response. 抑制细胞在调节免疫反应。
Progress in clinical immunology Pub Date : 1977-01-01
T A Waldmann, S Broder
{"title":"Suppressor cells in the regulation of the immune response.","authors":"T A Waldmann,&nbsp;S Broder","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76367,"journal":{"name":"Progress in clinical immunology","volume":"3 ","pages":"155-99"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11289253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of immunodeficiency diseases by organ transplantation. 器官移植治疗免疫缺陷疾病。
Progress in clinical immunology Pub Date : 1977-01-01
R Parkman
{"title":"Treatment of immunodeficiency diseases by organ transplantation.","authors":"R Parkman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76367,"journal":{"name":"Progress in clinical immunology","volume":"3 ","pages":"85-102"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11240193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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