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Proceedings of the Australian Association of Neurologists最新文献

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Epilepsy and driving. 癫痫和驾驶。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
K S Millingen
{"title":"Epilepsy and driving.","authors":"K S Millingen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>205 actual and potential drivers suffering from epilepsy were examined over a period of nine years in Tasmania under a State scheme whereby all such persons are referred to one neurologist. In Tasmania 0.3% of all road traffic accidents were due to epilepsy. 16% of the total who had had an accident had failed to disclose their disability and another 10% who were non-accident cases had similarly concealed their epilepsy. Only about 28% of the expected number (per year) of new cases of epilepsy in drivers disclose their complaint. Alcohol was a significant association with epilepsy in just over 8%. Medication should continue for at least three consecutive fit-free years and preferable five years. Only two out of 170 drivers approved to drive had a subsequent accident due to epilepsy.</p>","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12208306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An animal model for the study of drugs in the central nervous system. 中枢神经系统药物研究的动物模型。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
G J Parry
{"title":"An animal model for the study of drugs in the central nervous system.","authors":"G J Parry","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An animal model which allowed repetitive sampling of CSF is described. It had a wide potential application and was used to study the passage of clonazepam into the central nervous system. A highly sensitive clonazepam assay is described which allow measurement of CSF and free serum concentrations as low as 0.5 ng/ml. Clonazepam passed rapidly into the central nervous system and its CSF concentration closely approximated to the concentration of unbound clonazepam in serum. Protein binding of clonzaepam in the sheep was 90-95%.</p>","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"83-8"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12208309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrophysiological and pathological studies in spinocerebellar degenerations. 脊髓小脑变性的电生理和病理研究。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
J G McLeod, J A Morgan
{"title":"Electrophysiological and pathological studies in spinocerebellar degenerations.","authors":"J G McLeod,&nbsp;J A Morgan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Electrophysiological and pathological studies have been performed on the peripheral nerves of patients with spinocerebellar degenerations. In Friedreich's ataxia there is impairment of sensory conduction and mild slowing of motor conduction which may be correlated with loss of large diameter fibres in the sural nerve. The abnormalities in Friedreich's ataxia are present early, in the first decade. In hereditary spastic paraparesis the nerve conduction studies and sural nerve biopsy are normal. In the other spinocerebellar degeneration and a mild loss of myelinated fibres in the sural nerve. However the abnormalities differ from those seen in Friedreich's ataxia.</p>","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"113-7"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12209964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serial nerve conduction studies in patients with maturity onset diabetes mellitus. 成熟型糖尿病患者神经传导的系列研究。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
G Danta
{"title":"Serial nerve conduction studies in patients with maturity onset diabetes mellitus.","authors":"G Danta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serial study of peripheral nerve conduction in 18 patients with recently diagnosed maturity onset diabetes mellitus during a period of treatment of hyperglycaemia for 21/2 years showed improvement in motor conduction progressive increase in mixed nerve conduction velocity, but at the same time progressive fall of amplitude of sensory nerve action potentials. It is argued that two independent metabolic processes may underlie peripheral nerve dysfunction in these patients, only one of which is benefically affected by control of hyperglycaemia.</p>","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"123-6"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12209966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computerized axial tomography for intracranial diagnosis. 计算机轴位断层扫描颅内诊断。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
L A Cala
{"title":"Computerized axial tomography for intracranial diagnosis.","authors":"L A Cala","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"24-9"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12209970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measurement of cerebrospinal fluid IgG in the diagnosis of multiple sclerosis. 脑脊液IgG检测对多发性硬化症的诊断价值。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
E W Willoughby
{"title":"Measurement of cerebrospinal fluid IgG in the diagnosis of multiple sclerosis.","authors":"E W Willoughby","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>CSF IgG was measured in 190 patients by Single Radial Immunodiffusion, A high value for the ratio CSF IgG/total protein (normal values being up to 14%) was obtained in 13 of 22 patients (54%) with definite or probable multiple sclerosis and in 16 of 137 patients (12%) with other neurological disorders excluding acute infections, subarachnoid haemorrhage and neurosyphilis. In 56 patients IgG and albumin were measured in CSF and serum using Rocket Immunoelectrophoresis (Electroimmunodiffusion) and results assessed by dividing the radio IgG/albumin in the CSF by the same ratio in the serum to obtain an Index. Because of the small number of normal patients, it was not possible to define a normal range but separation of patients with multiple sclerosis from those with other neurological disorders was even less clear-cut than with first method. Minor technical difficulties with the Rocket technique and prolonged storage of some of the specimens may at least partly explain the discouraging results with this method. It was concluded that the measurement of CSF IgG was of limited value to a clinican attempting to make a diagnosis in an individual patient with neurological disease.</p>","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"127-33"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12015981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The continual administration of neostigmine and the neuromuscular junction. 持续使用新斯的明和神经肌肉连接处。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
J D Gillies, J Allen
{"title":"The continual administration of neostigmine and the neuromuscular junction.","authors":"J D Gillies,&nbsp;J Allen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of continual administration of neostigmine on the neuromuscular junction of the rat diaphragm was examined by determining the number of quanta of acetylcholine released by each nerve impulse, the effect of differing repetition rats on quantal release and the amplitude and frequency of miniature end-plate potentials. The number of quanta of acetylcholine released at a nerve impulse repetition rate of 1/sec was reduced to 51% of normal in treated animals. The reduction was greater at faster repetition rates. The amplitude of miniature end-plate potentials was reduced to 75% of normal. This reduction appears to be due to blocking of receptor sites rather than the reduction in the amount of acetylcholine in each quantum. The frequency of spontaneous miniature end-plate potentials was reduced in treated animals.</p>","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"149-53"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12209968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hereditary hypertrophic neuropathy in the Trembler mouse: electrophysiological studies. 震颤鼠的遗传性肥厚性神经病:电生理研究。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
P A Low, J G McLeod
{"title":"Hereditary hypertrophic neuropathy in the Trembler mouse: electrophysiological studies.","authors":"P A Low,&nbsp;J G McLeod","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"31-4"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12209971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computerized axial tomography findings in a group of patients with migrainous headaches. 一组偏头痛患者的计算机轴位断层扫描结果。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
L A Cala, F L Mastaglia
{"title":"Computerized axial tomography findings in a group of patients with migrainous headaches.","authors":"L A Cala,&nbsp;F L Mastaglia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Computerized axial tomography of the cranium has been carried out in 46 patients referred because recurring migrainous headaches. Increasing frequency or severity of headaches or a change in headache pattern were the usual reasons for referral. Abnormalities were found in 37 cases and fell into 4 categories. The most frequent (21 cases) consisted of a mild degree of oedema in the white matter of one or both cerebral hemispheres. This was usually bi-frontal (15 patients) but was more extensive in 2 patients. Varying degrees of cerebral atrophy, as determined by widening of the Sylvian, brain-stem and interhemispheric cisterns, and/or widening of the third and lateral ventricles as compared to a group of normal scans, was found in 8 cases. Areas of occipital infarction were found in 4 patients with permanent visual field defects. Unexpected small areas of infarction were found in the temporal lobe in 2 other cases. Cerebral tumours were found in 2 cases. The significance of these findings is discussed, as well as the possible role of migrainous vaso-spasm with consequent changes in cerebral blood flow in the pathogenesis of oedema and atrophy in migraine subjects.</p>","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"35-41"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12209972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three cases of post traumatic vascular headache treated by surgery. 手术治疗外伤性血管性头痛3例。
Proceedings of the Australian Association of Neurologists Pub Date : 1976-01-01
J T Holland
{"title":"Three cases of post traumatic vascular headache treated by surgery.","authors":"J T Holland","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Three cases are reported of vascular headache following trauma and which failed to respond adequately to standard therapy for migraine. In each case the effect of ligation of the arteries involved has been dramatic, with complete and lasting relief in two cases.</p>","PeriodicalId":76351,"journal":{"name":"Proceedings of the Australian Association of Neurologists","volume":"13 ","pages":"51-4"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12208304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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