Patologia polska最新文献

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The malignant form of calcifying odontogenic cyst. A case report. 钙化牙源性囊肿的恶性形式。一份病例报告。
Patologia polska Pub Date : 1993-01-01
M Dubiel-Bigaj, E Olszewski, J Stachura
{"title":"The malignant form of calcifying odontogenic cyst. A case report.","authors":"M Dubiel-Bigaj,&nbsp;E Olszewski,&nbsp;J Stachura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A rare case of the malignant form of Gorlin's cyst is reported in a 42-year-old woman. The neoplasm developed in the right maxilla, infiltrated the anterior wall and roof of the sinus and grew into the nasal cavity. Based upon literature data we characterized various clinical and histological forms of Gorlin's cyst (calcifying odontogenic cyst).</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 1","pages":"39-41"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19469732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proliferating cell nuclear antigen in archival surgical specimens of malignant lymphoma and metastatic carcinoma: immunohistochemical and flow cytometric analysis. 恶性淋巴瘤和转移癌手术标本中的增殖细胞核抗原:免疫组织化学和流式细胞术分析。
Patologia polska Pub Date : 1993-01-01
W Gorczyca, A Kram, T Tuziak, Z Darzynkiewicz, M R Melamed
{"title":"Proliferating cell nuclear antigen in archival surgical specimens of malignant lymphoma and metastatic carcinoma: immunohistochemical and flow cytometric analysis.","authors":"W Gorczyca,&nbsp;A Kram,&nbsp;T Tuziak,&nbsp;Z Darzynkiewicz,&nbsp;M R Melamed","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Immunohistochemical and flow cytometric multiparameter analysis of proliferating cell nuclear antigen (PCNA) was performed on fifteen formalin fixed, paraffin embedded lymph nodes with malignant lymphoma (eleven non-Hodgkin's lymphomas, four Hodgkin's lymphomas), and fifteen lymph nodes with metastatic carcinomas. A general concordance between PCNA measurement by both methods has been observed: the percentage of positively stained cells in tissue sections correlated well with the percentage of cells expressing this antigen in cell suspensions (r = 0.76). Both diploid and aneuploid tumors expressed PCNA, and a correlation between PCNA and the percent cells in S-phase was evident in both: in PCNA-positive tumors the mean percent of cells in S-phase was 16.5%, and in PCNA-negative tumors, 5.9%. The data indicate that PCNA can be detected in formalin-fixed tissues by either classic immunohistochemical analysis or by flow cytometry.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 3","pages":"121-8"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18898991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Proposed standardization of histo-oncologic diagnosis and terminology]. [组织肿瘤学诊断和术语标准化建议]。
Patologia polska Pub Date : 1993-01-01
L Woźniak, K W Zieliński, A Kulig
{"title":"[Proposed standardization of histo-oncologic diagnosis and terminology].","authors":"L Woźniak,&nbsp;K W Zieliński,&nbsp;A Kulig","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 4","pages":"177-81"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19298217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic and epigenetic mechanisms for the limited lifespan and ageing of normal, diploid cells. 正常二倍体细胞有限寿命和老化的遗传和表观遗传机制。
Patologia polska Pub Date : 1993-01-01
Z Srebro
{"title":"Genetic and epigenetic mechanisms for the limited lifespan and ageing of normal, diploid cells.","authors":"Z Srebro","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The genetic basis of the limited lifespan and apparently programmed number of divisions in normal, diploid cells is discussed. Two different mechanisms may underlie a programmed inhibition of cell divisions before they age and die: 1. A genetic mechanism involving the CpG sequence in promotor regions of genes. Inactive, but gradually activated basic function genes such as ribosomal and energy metabolism genes, when inactive have their CpG promotor sequences methylated. During each cell division a proportion of 5-methyl cytosines will be oxidatively deaminated leading to C to T transitions. After a certain number of divisions all methylated CpG islands will be mutated with consequent loss of viability and cell death. 2. An epigenetic mechanism involving the methylated promotor sequences of silent growth control genes. After a certain number of divisions with incomplete maintenance methylation, the growth control genes will be derepressed with consequent cessation of proliferation, decline of metabolic activity, ageing, and death.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 4","pages":"189-91"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19298219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The level of immunoglobulins in the small and large intestinal mucosa from children with ulcerative colitis. 溃疡性结肠炎患儿小肠和大肠黏膜免疫球蛋白水平的研究。
Patologia polska Pub Date : 1993-01-01
K Grzybowska, W Kozłowski
{"title":"The level of immunoglobulins in the small and large intestinal mucosa from children with ulcerative colitis.","authors":"K Grzybowska,&nbsp;W Kozłowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 42 children 4 to 16 years old with ulcerative colitis by using peroxidase method and monoclonal antibodies we evaluated the presence of immunoglobulin A, M, G, E in the mucosa of the large and small intestines. It was found that the distribution of immunoglobulins in the acute phase was similar in the intestinal segments studied, which supports the opinion that the whole intestine has a common immune system playing a major role in the pathogenesis of the disease.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 4","pages":"217-20"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19298222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amyloid tumour (amyloidoma) of the mediastinum. 纵隔淀粉样瘤(淀粉样瘤)。
Patologia polska Pub Date : 1993-01-01
B Papla, M Harazda, M Lukasiewicz, J Młodkowski
{"title":"Amyloid tumour (amyloidoma) of the mediastinum.","authors":"B Papla,&nbsp;M Harazda,&nbsp;M Lukasiewicz,&nbsp;J Młodkowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A unique case of a surgically treated primary amyloid tumour of the mediastinum has been reported in a 40-year-old man. Immunohistochemical examinations revealed the presence of transthyretin and amyloid AA within the amyloid masses.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 4","pages":"227-31"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19298224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypothalamic and neurohypophysial vasopressin and oxytocin content as influenced by haemorrhage in melatonin-treated male rats. 褪黑激素治疗的雄性大鼠出血对下丘脑和神经垂体加压素和催产素含量的影响。
Patologia polska Pub Date : 1993-01-01
M Juszczak, A K+opotowska, B Stempniak, J W Guzek
{"title":"Hypothalamic and neurohypophysial vasopressin and oxytocin content as influenced by haemorrhage in melatonin-treated male rats.","authors":"M Juszczak,&nbsp;A K+opotowska,&nbsp;B Stempniak,&nbsp;J W Guzek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of haemorrhage (1 ml per 100 g b. w.) on the vasopressin and oxytocin storage in the hypothalamus and neurohypophysis of melatonin-treated male rats was determined. Melatonin treatment (100 micrograms/100 g b. w., once daily over 8 days) resulted in a known decrease of vasopressin as well as oxytocin content both in the hypothalamus and neurohypophysis. Haemorrhage decreased the neurohypophysial vasopressin and oxytocin storage in animals injected with vehicle solution or otherwise not treated. In melatonin-treated rats, however, bleeding did not affect the actual (i.e., decreased by melatonin) vasopressin and oxytocin content in the hypothalamo-neurohypophysial system. The results demonstrate that melatonin may be involved in mechanisms determining the rate of the response of vasopressinergic and oxytocinergic neurones to bleeding.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 2","pages":"55-9"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19352967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Some remarks on the growth-rate and angiogenesis of microvessels in ischemic stroke. Morphometric and immunocytochemical studies. 缺血性脑卒中微血管生长速率及血管生成的几点评述。形态计量学和免疫细胞化学研究。
Patologia polska Pub Date : 1993-01-01
J Krupiński, J Kałuza, P Kumar, S Kumar, J M Wang
{"title":"Some remarks on the growth-rate and angiogenesis of microvessels in ischemic stroke. Morphometric and immunocytochemical studies.","authors":"J Krupiński,&nbsp;J Kałuza,&nbsp;P Kumar,&nbsp;S Kumar,&nbsp;J M Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Variability in microvessel changes of blood vessel density has prompted us to undertake quantitative morphometric studies of infarcted areas in human brain. In the initial study, brains were obtained at autopsy from 10 patients (ages 45-85). Samples were collected from infarcted hemisphere and controls from the contralateral hemisphere. Formalin fixed, paraffin embedded and thereafter routinely processed sections were stained after Pickworth and with HE. Altogether 6,520 microvessels, representing 10,801 microscopic fields were counted. The Wilcoxon Range test was used for statistical analysis. In 9 of 10 patients in infarcted brain hemispheres, there was a marked increase in microvessel density (p < 0.01), when compared with contralateral brain hemisphere. In addition, a positive correlation was also found between the time of survival and both total density and density of non-perfused blood vessels. To gain a deep insight into the enhanced activity of microvessels, immunocytochemical studies were performed, which have shown, that the vascular endothelial cells in infarcted brain were reactive to two monoclonal antibodies, one, E-9, directed against an activation/proliferation associated endothelial cell specific protein and the other recognizing adhesion molecule VCAM-1. Pan-endothelial Mab PECAM/CD31 was used in those studies for controls and confirmed the obtained results. Our findings strongly support the concept of angiogenesis in the infarcted area. If correlated with morphometric results, it may indicate an important role of microvessels in pathobiology of ischemic stroke.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 4","pages":"203-9"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18515973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor-like intravascular proliferations of the stroma in adenomyosis. 子宫腺肌病间质肿瘤样血管内增生。
Patologia polska Pub Date : 1993-01-01
W Sieiński
{"title":"Tumor-like intravascular proliferations of the stroma in adenomyosis.","authors":"W Sieiński","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two hundred cases of adenomyosis have been studied in order to clarify the origin and significance of intravascular endometrial tissue in adenomyosis. A tumor-like intravascular proliferation of the adenomyotic stroma (IVSP) has been found in 17.5% of the cases. An endolymphatic proliferation (35 cases) was occasionally accompanied by an intravenous proliferation (3 cases). IVSP originated from a perivascular stromal proliferation (PVSP) and occurred only in deep adenomyosis. IVSP was focal and showed no atypia. It was significantly most frequent in patients 50-53 years of age and more frequent in patients up to 53 years than in those over 53. The frequency of occurrence of PVSP and IVSP was related to the histologic features of adenomyosis and the endometrium and was highest in hyperplastic adenomyosis and in adenomyosis accompanied by hyperplasia of the endometrium. The study suggests that PVSP and IVSP develop in the areas of adenomyotic stroma stimulated by estrogen and nonresponsive to progesterone. The differential diagnosis of tumor-like and sarcomatous IVSP, and histogenesis of adenomyosis are discussed.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19469727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Porphobilinogen deaminase activity in malignant proliferative disorders of the lymphatic system and bone marrow. 淋巴系统和骨髓恶性增生性疾病中卟啉胆色素原脱氨酶的活性。
Patologia polska Pub Date : 1993-01-01
B Zawirska, L Usnarska-Zubkiewicz, E Gamian
{"title":"Porphobilinogen deaminase activity in malignant proliferative disorders of the lymphatic system and bone marrow.","authors":"B Zawirska,&nbsp;L Usnarska-Zubkiewicz,&nbsp;E Gamian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Porphobilinogen deaminase activity was studied in the erythrocytes of 73 women and 35 men with various malignant proliferative disorders of the lymphatic system and bone marrow, and, for comparison, in the erythrocytes of 34 women and 14 men with non malignant diseases of the haemopoietic system, and in those of 20 healthy women and 20 healthy men. The activity of the enzyme was determined by the Hsiao et al. method, using porphobilinogen as a substrate. Statistical analysis showed a significant decrease of porphobilinogen deaminase activity in the erythrocytes of men with Hodgkin's disease and women with plasmocytoma and with myeloblastic leukemia; an increased activity of the studied enzyme was found only in men with lymphocytic leukemia.</p>","PeriodicalId":76310,"journal":{"name":"Patologia polska","volume":"44 1","pages":"13-7"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19469728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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