Nihon Gan Chiryo Gakkai shi最新文献_第5页

[Study of bone metabolism for breast cancer by MD (microdensitometry) method]. [MD (microdensity ometry)法研究乳腺癌骨代谢]。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-10-20

S Suzuki, I Kimijima, M Nihei, H Mizunuma, K Kiman, Y Hatakeyama, T Nomizu, A Tsuchiya, R Abe

引用次数: 0

[Clinical studies on 29 cases of testicular tumors]. [29例睾丸肿瘤临床分析]。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-10-20

S Kawamura, K Takata, I Yoshida

引用次数: 0

Effects of etoposide (VP-16) on the survival and progression of cultured HeLa S3 cells through the cell cycle. 依托泊苷(VP-16)对体外培养的HeLa S3细胞在细胞周期内存活和进展的影响。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-10-20

S Obata, Y Yamaguchi, T Miyamoto

引用次数: 0

[Treatment and prognosis of primary malignant melanoma of the oral cavity--an analysis of 12 cases and 96 reported cases]. 【原发口腔恶性黑色素瘤的治疗及预后——附12例96例报告分析】。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-10-20

M Umeda, O Teranobu, K Nakanishi, K Shimada

引用次数: 0

[Effective continuous intraarterial chemotherapy for a patient with FIGO stage IIIb cervical adenocarcinoma invasing the bladder wall]. [1例FIGO IIIb期宫颈腺癌浸润膀胱壁的有效持续动脉内化疗]。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-10-20

Y Shimizu, H Teshima, I Fujimoto, K Hasumi, K Masubuchi

{"title":"[Effective continuous intraarterial chemotherapy for a patient with FIGO stage IIIb cervical adenocarcinoma invasing the bladder wall].","authors":"Y Shimizu, H Teshima, I Fujimoto, K Hasumi, K Masubuchi","doi":"","DOIUrl":"","url":null,"abstract":"A patient with FIGO stage IIIb adenocarcinoma of the uterine cervix (moderately differentiated, endocervical type) underwent an exploratory laparotomy because of a direct cancer invasion to the bladder wall, and then she was treated with consecutive intraarterial (IA) CDDP (10 mg/day) combined with continuous IA 5-FU (250 mg/day). Six weeks after, CR (complete response) was obtained by this IA chemotherapy (total dose; 5-FU: 10,500 mg, CDDP: 300 mg). Further 5-weeks-IA chemotherapy was added to keep the \"CR\" effect (final total dose; 5-FU: 19,250 mg, CDDP: 500 mg). The only toxic sign was a mild nausea. The patient's PS (performance status) was 0 (normal activity) and thereafter she could undergo a \"curative\" radical hysterectomy. The cancer invasion to the bladder wall observed at the first exploratory surgery completely disappeared histologically as well as macroscopically. In obtained material, small \"viable\" cancer focus was found in the cervical canal but the margin was free, and all nodes were negative. Postoperatively, the patient has receiving a continuous IA 5-FU (125 mg/day) for 13 months as a maintenance and she is free of disease (NED) with a normal activity (PS = 0). The present treatment modality is considered to be promising for advanced cervical adenocarcinoma having a poor prognosis due to its low sensitivity to radiotherapy.","PeriodicalId":76232,"journal":{"name":"Nihon Gan Chiryo Gakkai shi","volume":"25 10","pages":"2584-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13413571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Study on endoscopic features in responders to systemic chemotherapy in advanced gastric cancer]. 进展期胃癌全身化疗应答者的内镜特征研究

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-10-20

K Yasutake, M Tokisue, T Masuda, S Ono, Y Yoshimura, K Yasutake, Y Imamura, M Oya, K Matsushita

引用次数: 0

[28th meeting of the Japan Society for Cancer Therapy. Tokyo, 3-5 October 1990. Abstracts]. [日本癌症治疗学会第28次会议]。东京，1990年10月3日至5日。摘要]。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-09-01

引用次数: 0

[In vivo anti-tumour efficacy of tumour necrosis factor and interferon- alpha, -gamma on human renal cell carcinoma heterotransplanted in nude mice]. [肿瘤坏死因子和干扰素- α、- γ对人肾细胞癌裸鼠移植的体内抗肿瘤作用]。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-08-20

T Onishi, T Machida, F Masuda, N Iizuka, K Nakauchi, N Furuta, H Shirakawa

{"title":"[In vivo anti-tumour efficacy of tumour necrosis factor and interferon- alpha, -gamma on human renal cell carcinoma heterotransplanted in nude mice].","authors":"T Onishi, T Machida, F Masuda, N Iizuka, K Nakauchi, N Furuta, H Shirakawa","doi":"","DOIUrl":"","url":null,"abstract":"Using human renal cell carcinoma heterotransplanted in nude mice (JRC 11: anaplastic and alveolar pattern, grade IV), the in vivo anti-tumour efficacy of tumour necrosis factor (rHu-TNF-alpha: PT-050) and IFN-alpha (nHu-IFN-alpha: HLBI), IFN-gamma (nHu-IFN-gamma: OH-6000) were investigated. The dose of TNF was 1,000, 3,000, 10,000 J.R.U. (i.p., every day), that of IFN-alpha was 1 x 10(4) and 1 x 10(5) I. U. (s.c., every day) and that of IFN-gamma was 1 x 10(4) and 1 x 10(5) I.U. (s.c., every day). Mono-therapy of TNF, IFN-alpha and IFN-gamma was not effective with regard to tumour regression rates, histological degeneration rates and survival time of the host mice. Combination therapy of TNF and IFN-alpha, IFN-gamma were also not effective with regard to tumour regression rates, but when considering histological change, sporadic disappearance of endothelium of intra-tumoural vasculature, flow of tumour cells clustered in intra-vascular cavity, and extra-vascular bleeding were observed. With special reference to survival of host mice, prominent prolongation of survival time in combination treatment, especially in TNF combination therapy groups with the dosage of 10,000 J.R.U. was observed. Therefore we concluded that there is no synergistic reaction in combination therapy of TNF and IFN against JRC 11 tumour. But combined activity of TNF and IFN on the vasculature of renal cell carcinoma (JRC 11) and the suppression of cachexia related condition were detected.","PeriodicalId":76232,"journal":{"name":"Nihon Gan Chiryo Gakkai shi","volume":"25 8","pages":"1571-8"},"PeriodicalIF":0.0,"publicationDate":"1990-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13276813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Experimental and clinical study on injection of neocarzinostatin into the duodenal sub-serosa as chemotherapy for the regional lymphatic system in pancreatoduodenal cancer]. [十二指肠浆膜下注射新羧抑素作为胰十二指肠癌局部淋巴系统化疗的实验与临床研究]。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-08-20

Y Hase

{"title":"[Experimental and clinical study on injection of neocarzinostatin into the duodenal sub-serosa as chemotherapy for the regional lymphatic system in pancreatoduodenal cancer].","authors":"Y Hase","doi":"","DOIUrl":"","url":null,"abstract":"Unlabelled: At the time of pancreatoduodenal cancer resection, Neocarzinostatin (NCS) was injected into the duodenal sub-serosa, as perioperative adjuvant chemotherapy for metastatic lymph nodes and cancer cells released into the lymphatic system. NCS content in the lymph nodes was measured after administration, and usefulness of the chemotherapy was investigated.Experiment: NCS (4,000 units) was administered into the duodenal sub-serosa of 18 adult mongrel dogs. NCS contents in the lymph nodes (those in the root of the mesentery and around the aorta) and pancreatic tissues were measured. NCS content in the pancreatic tissues decreased significantly 3 hours after administration, while that in the lymph nodes did not decreased even 3 hours later. Consequently, NCS is considered to be remain in the lymph nodes.Clinical findings: NCS (10,000 units) was administered into the duodenal sub-serosa in 18 resectable cases of pancreatoduodenal cancer. NCS content in the dissected lymph nodes was measured. The total number of dissected lymph nodes was 176, and the mean NCS content was 0.62 mu/g. The number of lymph nodes positive for metastasis was 14, and much content of NCS was observed in the specimens (mean NCS content: 1.25 mu/g). Examination according to site revealed the most content in the lymph nodes in pancreatic head closest to the site of administration, followed by the lymph nodes in the root of the mesentery and those in the hepatoduodenal ligament in the direction of lymphatic flow. Moreover, some distal lymph nodes also showed much content. NCS content in the lymph nodes showed time-related increase after administration, and significant correlation was observed within 2 hours.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":76232,"journal":{"name":"Nihon Gan Chiryo Gakkai shi","volume":"25 8","pages":"1550-7"},"PeriodicalIF":0.0,"publicationDate":"1990-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13300246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Combination of adoptive immunotherapy and chemotherapy against advanced cancer with peritoneal dissemination]. 【过继性免疫治疗与化疗联合治疗晚期肿瘤伴腹膜播散】。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-08-20

M Iwahashi, H Tanimura, H Yamaue, T Tsunoda, M Tani, M Tamai, K Taniguchi, Y Aoki

引用次数: 0