{"title":"Ketamine as a Mental Health Treatment.","authors":"Liz Braun, Alison Colbert","doi":"10.1097/AJN.0000000000000250","DOIUrl":"10.1097/AJN.0000000000000250","url":null,"abstract":"<p><strong>Abstract: </strong>Ketamine has emerged as a promising intervention for treatment-resistant mental health disorders, such as depression, anxiety, and posttraumatic stress disorder. With rising global mental health burdens and the limitations of existing pharmacological treatments, ketamine's novel mechanism of action provides a potential alternative for individuals who have not responded to traditional therapies. Ketamine was initially approved by the U.S. Food and Drug Administration in 1970 for use as an anesthetic, and over the past two decades, has increasingly been investigated and used as an off-label treatment for mental health disorders. Additionally, the S-ketamine enantiomer of ketamine, esketamine (marketed as Spravato), received approval for treatment-resistant depression in 2019. Clinical applications of ketamine in the treatment of mental health disorders include intranasal administration (esketamine), IV infusions, ketamine-assisted psychotherapy, and at-home therapy, with varying levels of oversight. The current ketamine landscape has created a perfect storm in which the regulation of ketamine's use in mental health treatment remains fragmented, the evidence is constantly evolving, and a vulnerable population of individuals who are struggling with treatment-resistant mental health symptoms are desperate for relief. This article addresses these considerations by providing a foundation of clinical information that nurses should understand as they advise patients who are receiving, or curious about ketamine, as well as by discussing the regulatory, ethical, and nursing implications of using ketamine in the treatment of mental health disorders.</p>","PeriodicalId":7622,"journal":{"name":"American Journal of Nursing","volume":"126 3","pages":"24-30"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On the Cover.","authors":"","doi":"10.1097/AJN.0000000000000267","DOIUrl":"10.1097/AJN.0000000000000267","url":null,"abstract":"","PeriodicalId":7622,"journal":{"name":"American Journal of Nursing","volume":"126 3","pages":"15"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AI Won't Solve the Staffing Crisis-Safe Staffing Ratios Will.","authors":"Cathy Kennedy","doi":"10.1097/AJN.0000000000000256","DOIUrl":"10.1097/AJN.0000000000000256","url":null,"abstract":"<p><p>Protect nurses, so we can provide the hands-on care our patients deserve.</p>","PeriodicalId":7622,"journal":{"name":"American Journal of Nursing","volume":"126 3","pages":"9"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rural Primary Health Care Under Stress.","authors":"Karen Roush","doi":"10.1097/AJN.0000000000000266","DOIUrl":"10.1097/AJN.0000000000000266","url":null,"abstract":"<p><p>More than 90% of rural counties are health professional shortage areas.</p>","PeriodicalId":7622,"journal":{"name":"American Journal of Nursing","volume":"126 3","pages":"12-13"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Timple and colleagues respond.","authors":"","doi":"10.1097/AJN.0000000000000239a","DOIUrl":"10.1097/AJN.0000000000000239a","url":null,"abstract":"","PeriodicalId":7622,"journal":{"name":"American Journal of Nursing","volume":"126 3","pages":"6"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine Doyon, Sharon E Bigger, Kristin Snopkowski, Michal Temkin Martinez, William E Rosa, Adebusola Oluwatoba-Adeyemi, April Masarik
{"title":"Healing with Humility: Palliative Care for Refugee Communities.","authors":"Katherine Doyon, Sharon E Bigger, Kristin Snopkowski, Michal Temkin Martinez, William E Rosa, Adebusola Oluwatoba-Adeyemi, April Masarik","doi":"10.1097/AJN.0000000000000258","DOIUrl":"10.1097/AJN.0000000000000258","url":null,"abstract":"<p><strong>Abstract: </strong>Forced displacement has reached unprecedented levels, with over 120 million people uprooted globally and more than 100,000 refugees resettled in the United States in 2024. Refugees arrive with diverse cultural identities, prior professional roles, and experiences of trauma, yet often face systemic barriers, clinician bias, and unmet health needs. This article offers a practical framework grounded in holistic, person-centered values for delivering palliative nursing care to refugee communities. It outlines the complex resettlement journey and highlights how structural inequities, institutional racism, and communication barriers can undermine trust and care delivery. Cultural humility is defined and proposed as a guiding principle. Through real-world examples, communication strategies, and evidence-based insights, the authors demonstrate how care grounded in this principle can promote dignity, build trust, and improve outcomes. Special attention is given to interpreter use, social integration, and the importance of recognizing both cultural differences and individual strengths. When combined with the interdisciplinary, person-centered principles of palliative care-such as symptom management, effective communication, and cultural and spiritual respect-a strengths-based approach can enhance how care is delivered to displaced populations. By understanding the sociocultural and systemic factors that shape the refugee experience, nurses can better meet the complex needs of these patients and their families.</p>","PeriodicalId":7622,"journal":{"name":"American Journal of Nursing","volume":"126 3","pages":"31-35"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shameka L Cody, Christina J Ezemenaka, Cheryl B Hines, Stella M Rogers, Sharlene D Newman
{"title":"Naloxone Training Among Sorority-Affiliated College Students: An Observational Study.","authors":"Shameka L Cody, Christina J Ezemenaka, Cheryl B Hines, Stella M Rogers, Sharlene D Newman","doi":"10.1097/AJN.0000000000000257","DOIUrl":"10.1097/AJN.0000000000000257","url":null,"abstract":"<p><strong>Background: </strong>As a population, college students are known to be at risk for adverse substance use-related events, such as opioid overdose, as they seek relief from academic and social stressors. Sorority affiliation in this population is reputed to be another risk factor for increased substance use and misuse. Many college students are not aware that illicitly made fentanyl is often mixed with other commonly used substances, such as marijuana and cocaine (among others), potentially leading to unintentional overdose and even death. The timely administration of naloxone, an opioid antagonist, can save lives.</p><p><strong>Purpose: </strong>This observational pre-post study examined college-age, sorority-affiliated students' knowledge of opioids, opioid toxicity, and opioid overdose response both before and after an educational lecture and hands-on naloxone training. Participants' perceptions about the intervention's effectiveness were also explored.</p><p><strong>Methods: </strong>Eighty-four participants completed a knowledge-assessment questionnaire prior to receiving a brief lecture about opioids. The investigators then gave a hands-on training, demonstrating proper overdose response procedures and intranasal naloxone administration using a low-fidelity simulation manikin. Participants were then given the optional opportunity to practice and submit a return demonstration, which was scored using a behavioral rubric. A posttest questionnaire identical to the first was administered following this training. Lastly, an intervention effectiveness survey was administered to assess participants' understanding of and comfort level in responding to opioid overdose events. Participant characteristics and perceptions of the training's effectiveness were summarized using descriptive statistics. Paired t tests were used to compare pre- and posttest means.</p><p><strong>Results: </strong>Mean posttest total scores as well as posttest scores for individual components, including opioid knowledge, opioid toxicity, and opioid overdose response, were all significantly higher than mean pretest scores, indicating improvement following the hands-on training. The mean score on the behavioral rubric was 100 out of 100, indicating that of those participants who volunteered to practice and demonstrate responding to a simulated opioid overdose scenario, all responded correctly.</p><p><strong>Conclusions: </strong>This novel intervention, which combined didactic with hands-on learning methods, led to demonstrated improvements in knowledge of opioids, opioid toxicity, and opioid overdose response among sorority-affiliated college students. Routinely providing opioid education and practical hands-on naloxone training in college settings is recommended, and future studies should investigate students' long-term knowledge retention and real-world application of skills learned.</p>","PeriodicalId":7622,"journal":{"name":"American Journal of Nursing","volume":"126 3","pages":"20-23"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thousands of Research Grants Terminated Over the Past Year.","authors":"Karen Roush","doi":"10.1097/AJN.0000000000000266a","DOIUrl":"10.1097/AJN.0000000000000266a","url":null,"abstract":"<p><p>Science groups are compiling lists and offering guidance for appeals.</p>","PeriodicalId":7622,"journal":{"name":"American Journal of Nursing","volume":"126 3","pages":"13-14"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}