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Medical progress through technology最新文献

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Use of osteoinductive implants in the treatment of bone defects. 骨诱导植入物在骨缺损治疗中的应用。
Medical progress through technology Pub Date : 1994-01-01
M W Wolfe, S D Cook
{"title":"Use of osteoinductive implants in the treatment of bone defects.","authors":"M W Wolfe,&nbsp;S D Cook","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Osteogenic proteins (OPs) are a family of bone matrix polypeptides isolated from a variety of mammalian species, including mouse, rat, bovine, monkey, and man. OPs initiate chondroblastic differentiation in pluripotent mesenchymal progenitor cells, followed by the synthesis of new bone by endochondral ossification. OPs have the ability to induce healing of osteoperiosteal defects in several animal models, supporting a possible therapeutic role in the reconstruction of bone defects. OPs are responsible for the osteoinductive capacity of demineralized bone matrix (DBM) implants, which may also prove to be clinically useful. Preliminary studies using purified, naturally occurring human osteogenic proteins in the clinical management of non-unions have reported promising results. A prospective, randomized clinical trial is currently underway, comparing recombinant human osteogenic protein-1 (rhOP-1) to autograft in the treatment of tibial non-unions. The use of osteogenic protein implants to augment or replace autogenous and allogenous bone grafts will reduce morbidity, and circumvent the risk of disease transmission associated with transplantation.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 3-4","pages":"155-68"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18874497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of injectable filler materials for smoothing wrinkle lines and depressed scars. 可注射填充材料对平滑皱纹线和凹陷疤痕的有效性。
Medical progress through technology Pub Date : 1994-01-01
D P DeVore, E Hughes, J B Scott
{"title":"Effectiveness of injectable filler materials for smoothing wrinkle lines and depressed scars.","authors":"D P DeVore,&nbsp;E Hughes,&nbsp;J B Scott","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Both synthetic and biological materials have been used for smoothing wrinkle lines and depressed scars. Injectable fillers provide a convenient and easy alternative to surgical methods to treat dermal defects. Optimally, injectable fillers augmenting dermal tissue should exhibit properties similar to the dermal collagen network, providing a stable matrix for long-term correction but also being subject to the dynamic changes that occur to dermal tissue during the aging processes. At present, only biological materials are available on a commercial basis, although a number of synthetic injectables are being evaluated in clinical trials. The long-term effectiveness of most commercial materials has been limited prompting questions about the cost-benefits of such treatment. In this regard, the effectiveness of the injectable fillers, particularly of biological materials, will be discussed as will the difficulties involved in determining the expected result (effectiveness) for specific materials and in providing methods of measuring effectiveness.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 3-4","pages":"243-50"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18878697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interactions of enzymes and fungi with crosslinked polyurethanes prepared for biomedical applications. 酶和真菌与生物医学用交联聚氨酯的相互作用。
Medical progress through technology Pub Date : 1994-01-01
M Jayabalan, N Shunmugakumar
{"title":"Interactions of enzymes and fungi with crosslinked polyurethanes prepared for biomedical applications.","authors":"M Jayabalan,&nbsp;N Shunmugakumar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Shelf life and long-term environmental stability of polyurethanes intended for percutaneous applications and various biomedical applications are largely depend on their resistance to fungal attack and growth. Two classes of aliphatic crosslinked polyurethanes based on hexamethylene diisocyanate (HDI) and bicyclo-hexyl-methane diisocyanate (SM DI) were subjected to cell-free enzymatic degradation using hydrolytic and oxidative enzymes and to fungal attack and fungal growth using Aspergillus niger and Penicillium Sp. The present crosslinked polyurethanes are not susceptible to degradation by hydrolytic enzymes. The marginal loss of tensile strength in buffered solution of papain is attributed to plasticization by the absorbed components of the enzyme solution. The PEG based crosslinked polyurethanes are marginally susceptible to degradation by lactic dehydrogenase solution. The present polyurethanes are resistant to fungal attack. The fungal growth was not observed with PTMG and PPG based Polyurethanes, however, a marginal growth was observed with PEG based polyurethanes.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 3-4","pages":"261-70"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18876353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-invasive fetal electrocardiography. 无创胎儿心电图。
Medical progress through technology Pub Date : 1994-01-01
J R Mazzeo
{"title":"Non-invasive fetal electrocardiography.","authors":"J R Mazzeo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The recording of a fetal electrocardiogram from abdominal surface electrodes is severely obscured by additive noise. There are several sources of interference. A two-step method was used to filter the interferences. The mother's electrocardiogram is removed first. The second stage of the filter eliminates the remaining noise by means of coherent averaging techniques. These require the detection of fetal heartbeats. A detection algorithm is suggested that shows high efficiency in this environment, where signal-to-noise ratio is extremely low.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 1-2","pages":"75-9"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18964273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topographical characterization of normal visual evoked responses. 正常视觉诱发反应的地形特征。
Medical progress through technology Pub Date : 1994-01-01
V Medina, Y Grall, C Menguy, F Langevin, P Gaillard
{"title":"Topographical characterization of normal visual evoked responses.","authors":"V Medina,&nbsp;Y Grall,&nbsp;C Menguy,&nbsp;F Langevin,&nbsp;P Gaillard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study of visual evoked responses in a normal population was carried out using a high-precision programmable stimulator and an innovative brain mapping system which presents the overall activity on a three dimensional surface representing the human head. The interpolation method used gives a more precise computation of the potential value between electrodes. Two normal distributions of visual responses are presented which were identified while trying to topographically characterize visual evoked responses in order to construct a comparative data base. The proposed classification of two normal groups was verified by means of a statistical topographic analysis with the significance probability mapping technique.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 1-2","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18964340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An examination of two retrieved long-term human implant Björk-Shiley valves. 检查两个取出的长期人类植入物Björk-Shiley瓣膜。
Medical progress through technology Pub Date : 1994-01-01
R B More
{"title":"An examination of two retrieved long-term human implant Björk-Shiley valves.","authors":"R B More","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two retrieved long-term human implant Björk-Shiley valve prostheses were examined for wear. The prostheses were retrieved at necropsy from a double implant patient that had died from causes unrelated to the valves twelve years post implantation. Both prostheses were the Björk-Shiley conical tilting disc type heart valves with Haynes 25 alloy orifice and a Pyrolite Carbon disc. A size 21 mm valve had been implanted in the aortic position and a size 27 mm valve had been implanted in the mitral position. Wear had occurred on the valves in regions of mutual contact between the disc and orifice struts during valve opening and closing. Wear mark depths and types were consistent with previous observations on Pyrolite Carbon Björk-Shiley and Lillehi-Kaster prostheses. No evidence of cavitation nor strut fatigue damage was observed on either valve prosthesis. Wear that occurred on the valves was insignificant and of no consequence to valve function.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 3-4","pages":"195-200"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18878693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the durability of pyrolytic carbon in vivo. 热解碳在体内的耐久性研究。
Medical progress through technology Pub Date : 1994-01-01
A D Haubold
{"title":"On the durability of pyrolytic carbon in vivo.","authors":"A D Haubold","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The durability of pyrolytic carbon heart valve components was examined from the point of view of number implanted, documentation of wear on explanted components, and from the aspect of fatigue. Failures of pyrolytic carbon components were found to be few in number. A model describing the time course of events and successful usage of pyrolytic carbon components in heart valves was developed. The model is based on the yearly shipments of pyrolytic carbon components or valves, starting with 1969. The model indicates that about 2 million components have been successfully implanted, resulting in accumulative experience of over 10 million patient years. The wear of pyrolytic carbon, based on analysis of explanted heart valves, was found to be minimal. Additional wear data obtained on explanted components confirms the earlier observation that wear in vivo in less than that observed in vitro. The recently discovered fatigue behavior of pyrolytic carbon was found to have no demonstrated practical impact on the durability of pyrolytic carbon components used in existing mechanical heart valves.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 3-4","pages":"201-8"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18878694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fiberoptic transmission of biological signals. 生物信号的光纤传输。
Medical progress through technology Pub Date : 1994-01-01
M M Werneck, E M Barrientos
{"title":"Fiberoptic transmission of biological signals.","authors":"M M Werneck,&nbsp;E M Barrientos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This work presents a multiplexed transmission system for biological signals, making use of the advantages of fiberoptics as a transmission medium. The signals are pulse frequency modulated (PFM) at one end of the fiber and demodulated using the pase locked loop (PLL) technique at the other end. During tests two electrocardiogram (ECG) signals were transmitted. The signals recovered at the receptor presented very low noise and crosstalk. Following results from the test applied to the system are discussed along with possible expansions of the system which will enable transmission of eight simultaneous signals with one single fiber.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 1-2","pages":"59-62"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18964271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved automatized recording of masticatory reflexes through analysis of effort trajectory during biofeedback. 通过对生物反馈过程中努力轨迹的分析，改进了咀嚼反射的自动化记录。
Medical progress through technology Pub Date : 1994-01-01
C García Moreira, F Angeles Medina, H González Gómez, A Nuño Licona, J García Ruiz, A Galicia Arias, M Rodríguez Espinoza
{"title":"Improved automatized recording of masticatory reflexes through analysis of effort trajectory during biofeedback.","authors":"C García Moreira,&nbsp;F Angeles Medina,&nbsp;H González Gómez,&nbsp;A Nuño Licona,&nbsp;J García Ruiz,&nbsp;A Galicia Arias,&nbsp;M Rodríguez Espinoza","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tap and sound evoked inhibitory motor reflexes within masseteric EMG were studied by means of a new technique that uses real time analysis of the trajectory followed during voluntary occlusal effort, controlled through visual biofeedback, in order to stimulate on exactly the same activity background. This technique uses a two computers system, doing parallel processing to support data acquisition, video indication, calculus of the pursued trajectory and evaluation of it. Stimuli were automatically delivered when the effort's trajectory fulfilled a set of conditions. Denomination of reflexigram (RFXG) is proposed to the cumulative, rectified and filtered EMG's series so recorded. Normal morphologies of RFXG were established on a 90 normal patients group. Clear clinical correlations were also found within two groups: 30 bruxists and 50 with temporomandibular joint dysfunction.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 1-2","pages":"63-73"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18964272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multiprocessor architecture for medical image compression in a PACS environment. 用于PACS环境下医学图像压缩的多处理器体系结构。
Medical progress through technology Pub Date : 1994-01-01
J Azpiroz Leehan, J F Lerallut, I Magaña
{"title":"A multiprocessor architecture for medical image compression in a PACS environment.","authors":"J Azpiroz Leehan,&nbsp;J F Lerallut,&nbsp;I Magaña","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We present a new multiprocessor architecture for medical image compression using digital signal processors. The system has been designed to be used in a NuBus-based workstation and to apply different image compression algorithms to medical images. The system has been tested with a full-frame cosine transform and bit allocation table on several imaging modalities ranging from ultrasound to magnetic resonance imaging. Results show that image quality is acceptable when the allocation tables are calculated for each specific image modality. Implementation of algorithms such as wavelet transforms and vector quantization which respond to the characteristics of each type of image is in progress.</p>","PeriodicalId":76136,"journal":{"name":"Medical progress through technology","volume":"20 1-2","pages":"101-10"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18964338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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