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Major problems in internal medicine最新文献

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Liver disease. 肝脏疾病。
Major problems in internal medicine Pub Date : 1976-01-01
P D Zieve, J Levin
{"title":"Liver disease.","authors":"P D Zieve, J Levin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"10 ","pages":"89-92"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11977148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The syndromes of cardiac pain. 心脏疼痛的症状。
Major problems in internal medicine Pub Date : 1976-01-01
R Gorlin
{"title":"The syndromes of cardiac pain.","authors":"R Gorlin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"11 ","pages":"149-72"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12010116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physiology of myocardial blood flow and metabolism. 心肌血流和代谢生理学。
Major problems in internal medicine Pub Date : 1976-01-01
R Gorlin
{"title":"Physiology of myocardial blood flow and metabolism.","authors":"R Gorlin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this chapter the normal functioning of the coronary circulation has been described with major emphasis placed on the hydraulic and small vessel resistance factors in its regulation. The impact of various forms of disease to compromise effective delivery of blood flow either in general or segmentally has also been stressed. The vulnerability of the deep or subendocardial layers to ischemia has been emphasized. The distinction has been drawn between primary and secondary vasodilatation, the primary type representing effects on the arteriole, irrespective of effects on myocardial mechanical and metabolic activity, while the secondary type represents changes in response to changes in the metabolic rate. An interrelationship has been demonstrated among the several factors which regulate blood supply and affect myocardial mechanical activity.</p>","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"11 ","pages":"71-86"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12163077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathogenesis of atherosclerosis. 动脉粥样硬化的发病机制。
Major problems in internal medicine Pub Date : 1976-01-01
R Gorlin
{"title":"Pathogenesis of atherosclerosis.","authors":"R Gorlin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"11 ","pages":"29-39"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11402190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natural history of coronary heart disease. 冠心病的自然病史。
Major problems in internal medicine Pub Date : 1976-01-01
R Gorlin
{"title":"Natural history of coronary heart disease.","authors":"R Gorlin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We now possess enough data concerning prognosis so that we can highlight the areas of concentration for the practicing physician. A history of congestive failure, hypertension,or diabetes is of greatest importance. Smoking is in a similar category, but cholesterol elevation is not. Electrocardiographic findings can be used as an immediate discriminator, depending on whether they are normal or abnormal. Further refinements are possible, depending on whether there are ST-segment depressions or elevations, ventricular conduction defects, repetitive ventricular dysrhythmias, left ventricular hypertrophy, or Q waves of prior infarctions. The exercise electrocardiogram provides additional important information and, if markedly abnormal, can detect with reasonable degree of accuracy the presence and degree of ischemic heart disease. The coronary arteriogram, which influences many of the preceding clinical criteria, permits an accurate prediction of five-year mortality and in a preliminary fashion can be integrated with electrocardiographic and ventriculographic abnormalities to derive a significant measure of prognosis. Finally, cardiac function, if assessed according to specific criteria, becomes an extremely important variable in predicting natural history in coronary heart disease.</p>","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"11 ","pages":"195-215"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12159614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arrhythmias in coronary heart disease. 冠心病中的心律失常。
Major problems in internal medicine Pub Date : 1976-01-01
R Gorlin
{"title":"Arrhythmias in coronary heart disease.","authors":"R Gorlin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"11 ","pages":"216-31"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12163070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thrombocytopenia. 血小板减少症。
Major problems in internal medicine Pub Date : 1976-01-01
P D Zieve, J Levin
{"title":"Thrombocytopenia.","authors":"P D Zieve,&nbsp;J Levin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"10 ","pages":"24-39"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11977141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bleeding induced by anticoagulant drugs. 抗凝药物引起的出血。
Major problems in internal medicine Pub Date : 1976-01-01
P D Zieve, J Levin
{"title":"Bleeding induced by anticoagulant drugs.","authors":"P D Zieve,&nbsp;J Levin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"10 ","pages":"80-8"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11977147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronary anatomy. 冠状动脉解剖。
Major problems in internal medicine Pub Date : 1976-01-01
R Gorlin
{"title":"Coronary anatomy.","authors":"R Gorlin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The coronary arteries have a serpentine but interdependent relationship to one another. The left artery supplies the majority of the left ventricular myocardium irrespective of right or left arterial \"dominance.\" A coronary artery obstruction begins to assume significance when it approaches 75% of the cross-sectional area of the vessel. Increasing degrees of stenosis impose limitations to blood flow during stress and finally even under resting conditions. Analysis of the arteriogram requires not only knowledge of normal anatomy and its variations but also appreciation of difficulties in distinguishing a normal from an abnormal artery and in quantifying the functional severity of an obvious obstruction.</p>","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"11 ","pages":"40-58"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12163074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Principles in selection of therapy. 选择治疗的原则。
Major problems in internal medicine Pub Date : 1976-01-01
R Gorlin
{"title":"Principles in selection of therapy.","authors":"R Gorlin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The physician today is presented with a plethora of possibilities in the therapy of each of the aspects of ischemic heart disease (Fig. 15-5). There is the temptation to recommend complex and impossible dietary prescriptions coupled with several pharmaceutical agents for control of anginal pain, hypertension, arrhythmias, hypercholesterolemia, and clinical congestive heart failure. While each of the objectives may be in part valid, the burden on the patient of following such a constraining and difficult life may make it virtually impossible either to enjoy life or to follow the physician's recommendations explicitly. Often a compromise must be reached between theoretically optimal therapy and that which is reasonable and acceptable to the patient. Again, a review of each aspect of the program with the patient may aid in establishing that which is possible rather than that which is ideal.</p>","PeriodicalId":76120,"journal":{"name":"Major problems in internal medicine","volume":"11 ","pages":"293-310"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11234955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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