Journal of the Royal College of Surgeons of Edinburgh最新文献

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Focused rigidity casting: a prospective randomised study. 聚焦刚性铸造:一项前瞻性随机研究。
W N Martin, H Sandhu
{"title":"Focused rigidity casting: a prospective randomised study.","authors":"W N Martin, H Sandhu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 5","pages":"713-4; author reply 714"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22139758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment for pulmonary hydatidosis (a review of 422 cases). 肺包虫病的外科治疗(附422例报告)。
M Dakak, O Genç, S Gürkök, A Gözübüyük, K Balkanli
{"title":"Surgical treatment for pulmonary hydatidosis (a review of 422 cases).","authors":"M Dakak,&nbsp;O Genç,&nbsp;S Gürkök,&nbsp;A Gözübüyük,&nbsp;K Balkanli","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Hydatidosis in man is frequently encountered in sheep and cattle raising regions of the world. We reviewed 422 patients, treated surgically for pulmonary hydatid disease in our clinic between January 1980 and January 1998, assessing the clinical features and results of results of operative treatment management in our centre.</p><p><strong>Patients and methods: </strong>52 of the patients were female and 370 were male. The median age of the patients was 33 years (range, 11 to 66 years). The cysts were located in the right lung in 214 (50.7%) patients, the left lung in 156 (37%) and bilaterally in 17 (4%) cases. We found an intrathoracic extrapulmonary cyst in 35 (8.3%) patients. We performed enucleation and capitonnage in 202 cases, wedge resection in 40, cystotomy and capitonnage in 171, and lobectomy in 9 patients. The high-risk patients were treated with Albendazol (10 mg/kg/day), for a period of 3 months postoperatively.</p><p><strong>Results: </strong>Preoperative diagnosis was based primarily on chest roentgenograms and led to correct diagnosis in 347 cases (82.2%). An additional computerised tomography (CT) scan in 56 cases and magnetic resonavive imaging (MRI) were required in 15 cases. The diagnosis is established intraoperatively in 4 cases. Most (296) patients presented with a solitary lung cyst. The rest were found to have multiple cysts in one or more lobes. 87 of 422 also had cysts in the liver, 19 in the spleen, and 1 in the pancreas. The follow-up data was completed in 392 of 422 (92.8%) patients. The mean follow-up period was 4.3 years (2 to 19 years). We detected recurrence in 3 patients (0.71%).</p><p><strong>Conclusion: </strong>The effective treatment of hydatid cyst(s) in the lung is complete excision of the cyst(s) with maximum preservation of the lung parenchyma. Additional medical treatment with Albendazole should be carried out for high-risk group patients.</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 5","pages":"689-92"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22139752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast cancer in women aged 35 and under: prognosis and survival. 35岁及以下女性的乳腺癌:预后和生存。
S Jmor, H Al-Sayer, S D Heys, S Payne, I Miller, A Ah-See, A Hutcheon, O Eremin, S Jimor
{"title":"Breast cancer in women aged 35 and under: prognosis and survival.","authors":"S Jmor,&nbsp;H Al-Sayer,&nbsp;S D Heys,&nbsp;S Payne,&nbsp;I Miller,&nbsp;A Ah-See,&nbsp;A Hutcheon,&nbsp;O Eremin,&nbsp;S Jimor","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer comprises 22% of all cancers occurring in females but only 2% of cases occur in women aged 35 years and less. The presentation, behaviour and prognosis of breast cancer in such women, when compared with older women, are unclear and conflicting results have been reported. This study has audited clinical and pathological features in patients aged 35 years and under with breast cancer.</p><p><strong>Methods: </strong>One hundred and thirteen patients were identified. The details of clinical staging, local and distant disease recurrence and overall survival were obtained for all patients. Histological sections of tumours were examined for type, grade, size, presence of surrounding intraductal carcinoma, presence of vascular space invasion, lymph node involvement and oestrogen receptor (ER) status.</p><p><strong>Results: </strong>Histological examination of the tumours revealed that 94% were invasive ductal carcinoma. In 73% of the cases the tumours were grade 3, 49% of patients who underwent axillary surgery had lymph node involvement and 20% of tumours expressed ERs. The overall 5-year survival was 64%. Predictors of a poorer survival (univariate analysis) were: increasing tumour size, absence of ERs, presence of lymphovascular space invasion, axillary lymph node involvement and detectable metastases at the initial presentation. Multivariate analysis revealed that only lymphovascular space invasion was an independent predictor of a poor survival.</p><p><strong>Conclusion: </strong>Breast cancer in young (< or = 35 years) women is biologically aggressive, compared with older women. Factors predicting survival and overall survival rates, however, were comparable with those previously reported for older women with breast cancer.</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 5","pages":"693-9"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22139753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infective lumbar discitis following laparascopic sacrocolpopexy. 腹腔镜骶髋固定术后感染性腰椎间盘炎。
Birender Kapoor, Andy Toms, Paul Hooper, A M Fraser, C W F M Cox
{"title":"Infective lumbar discitis following laparascopic sacrocolpopexy.","authors":"Birender Kapoor,&nbsp;Andy Toms,&nbsp;Paul Hooper,&nbsp;A M Fraser,&nbsp;C W F M Cox","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Study design: </strong>A case report of infective lumbar discitis following laparoscopic sacrocolpopexy.</p><p><strong>Objectives: </strong>To improve awareness of the possibility of surgical procedures for genital prolapse causing discitis by presenting a case history.</p><p><strong>Background: </strong>Infective lumbar discitis following laparoscopic sacrocolpopexy is very rare.</p><p><strong>Methods: </strong>Case history of a 63 year old lady who developed infective L5-S1 discitis three weeks following a laparoscopic sacrocolpopexy.</p><p><strong>Conclusion: </strong>Discitis following a laparoscopic sacrocolpopexy procedure is a very rare but significant complication.</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 5","pages":"709-10"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22139756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimal access mitral valve replacement. 微创二尖瓣置换术。
D Richens, R S Jutley, M Baker, M Shajar
{"title":"Minimal access mitral valve replacement.","authors":"D Richens,&nbsp;R S Jutley,&nbsp;M Baker,&nbsp;M Shajar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Minimally invasive mitral valve surgery has recently been advocated as an alternative to the conventional median sternotomy approach. It has several documented advantages and requires a close relationship betweeen the surgeons, anaesthetist and perfusionist for a successful outcome. This article demonstrates our surgical technique for replacement of the mitral valve. The various aspects of the specialised equipment used are also described.</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 5","pages":"676-80"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22139832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic inguinal hernia repair: a NICE operation. 腹腔镜腹股沟疝修补术:NICE手术。
A M Pullyblank, L Carney, F Braddon, A R Dixon
{"title":"Laparoscopic inguinal hernia repair: a NICE operation.","authors":"A M Pullyblank,&nbsp;L Carney,&nbsp;F Braddon,&nbsp;A R Dixon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Published evidence comparing laparoscopic and open herniorraphy is controversial. NICE recommends that open techniques are used for first time repairs and that TEP be considered for bilateral/recurrent repairs undertaken in specialist units. We report a consecutive series of 224 patients undergoing 268 TEP repairs between 1996 and 2001. Operating time, complications, return to normal activity/full time employment and recurrence were examined. The median operating time was 30 minutes. There was one conversion. Ninety four percent of patients drove on the third post-operative day. The median time to normal activity was 4 days (1-10 days). The median time to return to professional employment in 82 patients was 3 days (range 2-9 days). Four patients (1.7%) had self-limiting minor groin pain. There were 3 recurrences (1.4%) and none since altering the surgical technique to use a larger anchored mesh. We have demonstrated TEP to be an easily learnt, safe, effective technique with low morbidity, and with sufficient experience, takes no longer than an open repair. It can be performed at little increased cost and restores selected patients to an early return to full-time employment. We believe that the choice between open and laparoscopic repair is a subjective decision for patient and surgeon</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 4","pages":"630-3"},"PeriodicalIF":0.0,"publicationDate":"2002-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22052385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parathyroid localisation--current practice. 甲状旁腺定位-目前的做法。
B Dijkstra, C Healy, L M Kelly, E W McDermott, A D K Hill, N O'Higgins
{"title":"Parathyroid localisation--current practice.","authors":"B Dijkstra,&nbsp;C Healy,&nbsp;L M Kelly,&nbsp;E W McDermott,&nbsp;A D K Hill,&nbsp;N O'Higgins","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In patients with primary hyperparathyroidism, neck exploration by an experienced parathyroid surgeon is curative in excess of 95% of cases. Considerable efforts have been devoted to improving parathyroid imaging. New radionucleotide agents and scanning procedures have markedly improved the success rate of localization studies with subsequent development of minimally invasive surgical techniques. In this article we review the different localization techniques and their current role in parathyroid surgery for primary hyperparathyroidism</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 4","pages":"599-607"},"PeriodicalIF":0.0,"publicationDate":"2002-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22054215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P53 pathways involving G2 checkpoint regulators and the role of their subcellular localisation. 涉及G2检查点调节因子的P53通路及其亚细胞定位的作用。
Z E Winters
{"title":"P53 pathways involving G2 checkpoint regulators and the role of their subcellular localisation.","authors":"Z E Winters","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>DNA damage activates checkpoint pathways to produce a G1 or G2 cell cycle arrest and DNA repair. G2 checkpoint integrity prevents inappropriate mitosis of unrepaired DNA. Cell cycle progression is determined by cyclin-dependent kinase (CDK) enzymes in association with specific cyclin proteins, with Cdc2/cyclin B regulating mitosis. The tumour suppressor p53 re-enforces G2 arrest through the CDK inhibitor, p21(WAF1/CIPI). Functional regulation of G2 checkpoint proteins occurs through levels of protein expression, phosphorylation and subcellular localisation</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 4","pages":"591-8"},"PeriodicalIF":0.0,"publicationDate":"2002-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22052379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single stage bipolar exclusion of oesophagus in failed primary repair for perforation. 食管穿孔一期修复失败的单期双极排除。
S G Iyer
{"title":"Single stage bipolar exclusion of oesophagus in failed primary repair for perforation.","authors":"S G Iyer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Perforation of the thoracic oesophagus is a serious clinical problem, associated with a high morbidity and mortality, especially if treated late. Primary repair with or without reinforcement is commonly recommended, if the patient presents within 24 hours. As the time to treatment increases, primary repair has a high rate of leakage and complications. A useful technique of temporary oesophageal exclusion and diversion with spontaneous recanalisation is presented. The technique obviates the need for thoracotomy and preserves the native oesophagus</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 4","pages":"623-5"},"PeriodicalIF":0.0,"publicationDate":"2002-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22052383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transient femoral nerve palsy following ilio-inguinal nerve blockade for day case inguinal hernia repair. 髂-腹股沟神经阻滞术后短暂性股神经麻痹行腹股沟疝修补术。
K R Ghani, R McMillan, S Paterson-Brown
{"title":"Transient femoral nerve palsy following ilio-inguinal nerve blockade for day case inguinal hernia repair.","authors":"K R Ghani,&nbsp;R McMillan,&nbsp;S Paterson-Brown","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Transient femoral nerve palsy (TFNP) has been reported in patients undergoing inguinal hernia repair involving the use of ilio-inguinal nerve block. Ilio-inguinal nerve blocks can be administered under vision by the surgeon or by the anaesthetist using a standard blind technique. There has been no study that has specifically examined the incidence of this complication and whether its development is related to the type of method used to administer the block.</p><p><strong>Patients and methods: </strong>Data on patients undergoing surgery in the Royal Infirmary Edinburgh Day Case Unit are collected prospectively. All patients who undergo inguinal hernia repair are given ilio-inguinal field blocks, either pre-operatively by anaesthetists (blind technique) or peri-operatively under direct vision by surgeons. Several cases of TFNP were initially identified during the process of surgical audit and this led to a retrospective analysis over a period of one year.</p><p><strong>Results: </strong>During a 12-month period, 194 patients underwent 200 open inguinal hernia repairs (188 unilateral and 6 bilateral), under general anaesthesia. Ten patients (5%) developed TFNP resulting in overnight admission. Surgeons administered 101 blocks under direct vision of which 4 (4%) resulted in TFNP, whereas 6 out of 99 (6%) blind blocks resulted in TFNP (p=0.49, df=1, Chi2 test).</p><p><strong>Discussion and conclusion: </strong>TFNP is a recognised complication following ilioinguinal nerve blockade for inguinal hernia surgery. Our series shows that ilio-inguinal block given under direct vision does not appear to reduce the chance of this complication occurring. This may result from the fact that this complication could be due to local infiltration into the operative field rather than direct infiltration around the femoral nerve. As inguinal hernia repair undertaken as a day case procedure increases, the awareness of this complication is important to avoid morbidity</p>","PeriodicalId":76058,"journal":{"name":"Journal of the Royal College of Surgeons of Edinburgh","volume":"47 4","pages":"626-9"},"PeriodicalIF":0.0,"publicationDate":"2002-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22052384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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