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International advances in surgical oncology最新文献

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Adjuvant immunotherapy. 辅助免疫治疗。
International advances in surgical oncology Pub Date : 1978-01-01
J E Goodnight, D L Morton
{"title":"Adjuvant immunotherapy.","authors":"J E Goodnight,&nbsp;D L Morton","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Because systemic spread occurs early in the growth of many malignancies, control of occult micrometastases must be an integral part of cancer treatment. For this reason, surgery and radiation therapy alone may fail to achieve a cure despite eradication of the primary tumor. Chemotherapy is potent and systemic in its effects but kills tumor cells by first-order kinetics so the last cancer cell may not be eliminated. An agent is needed that can selectively attack and destroy small numbers of tumor cells on a systemic basis without a significant increase in toxicity. Experimental observations indicate that immunotherapy could fill this role. Immunotherapy has been tested as an adjuvant to surgery, radiation therapy, and chemotherapy, and is clearly beneficial for selected cancer patients. There are many unresolved questions regarding the underlying mechanisms as well as the practical application of adjuvant immunotherapy, but the initial investigations indicate that it could play a vital part in the treatment of cancer. There is evidence that stimulation of host resistance can result in control of systemic micrometastases.</p>","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"53-83"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies of lymphocyte adenosine deaminase activity in patients with renal and transitional cell carcinoma. 肾和移行细胞癌患者淋巴细胞腺苷脱氨酶活性的研究。
International advances in surgical oncology Pub Date : 1978-01-01
G Sufrin, G L Tritsch, A Mittelman, G P Murphy
{"title":"Studies of lymphocyte adenosine deaminase activity in patients with renal and transitional cell carcinoma.","authors":"G Sufrin,&nbsp;G L Tritsch,&nbsp;A Mittelman,&nbsp;G P Murphy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Adenosine deaminase (ADA) is a critical enzyme in purine metabolism and lymphocyte ADA activity is specifically related to immunocompetence in man. Since immunologic factors are relevant in patients with renal and transitional cell carcinoma, we studied lymphocyte ADA activity in these patients. In renal adenocarcinoma patients lymphocyte ADA activity was reduced. Such reductions were most marked in low-as compared to high-stage lesions. Nephrectomy resulted in a rise and disease progression in a decline in ADA activity. In contrast, bladder, carcinoma patients showed elevated lymphocyte ADA activity most marked in high-stage lesions. Disease progression was associated with a rise and tumor resection with a decline in lymphocyte ADA activity. Discordance in patterns of lymphocyte ADA activity when patients with renal and transitional cell carcinoma are compared suggests unique host-tumor interactions at the enzyme level. Studies of ADA may offer insight into molecular aspects of immune mechanisms.</p>","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"11-28"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CO2 laser in surgical oncology. CO2激光在外科肿瘤学中的应用。
International advances in surgical oncology Pub Date : 1978-01-01
B L Aronoff
{"title":"CO2 laser in surgical oncology.","authors":"B L Aronoff","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"243-63"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11341781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of malignant phenotypes in familial polyposis. 家族性息肉病的恶性表型特征。
International advances in surgical oncology Pub Date : 1978-01-01
S A Wells, A H Johnson, R O Gregory
{"title":"Characteristics of malignant phenotypes in familial polyposis.","authors":"S A Wells,&nbsp;A H Johnson,&nbsp;R O Gregory","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Numerous clinical syndromes associated with multiple polypoid lesions of the gastrointestinal tract have been described. These syndromes generally have two striking characteristics: 1) Most of them are familial with the disease being inherited as a mendelian autosomal dominant trait, and 2) most of the affected patients have moderate to marked propensity to develop gastrointestinal carcinoma, usually of the large bowel. Whereas previously many of these syndromes were thought to be well-defined entities, it now appears that there is overlap between certain of them such that they appear more similar than different. The clinical and pathologic characteristics of the various gastrointestinal polyposis syndromes and the methods of diagnosis and treatment are reviewed in this manuscript.</p>","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"29-52"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11756787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New trends in the treatment of malignant melanoma. 恶性黑色素瘤治疗的新趋势。
International advances in surgical oncology Pub Date : 1978-01-01
U Veronesi, E Bajetta, N Cascinelli, C Clemente, F Rilke
{"title":"New trends in the treatment of malignant melanoma.","authors":"U Veronesi,&nbsp;E Bajetta,&nbsp;N Cascinelli,&nbsp;C Clemente,&nbsp;F Rilke","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"113-56"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recidivism of early gastric cancer. 早期胃癌的再犯。
International advances in surgical oncology Pub Date : 1978-01-01
N Sakakibara, K Ogawa, T Hashimoto, K Nakayama
{"title":"Recidivism of early gastric cancer.","authors":"N Sakakibara,&nbsp;K Ogawa,&nbsp;T Hashimoto,&nbsp;K Nakayama","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"157-72"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The laser in skin cancer. 激光治疗皮肤癌。
International advances in surgical oncology Pub Date : 1978-01-01
L Goldman
{"title":"The laser in skin cancer.","authors":"L Goldman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"217-26"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11341779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring of colon cancer through measurement of carcinoembroyonic antigen levels, tests of cellular immune competence, and tumor specific immunity. 通过测量癌胚抗原水平、细胞免疫能力测试和肿瘤特异性免疫来监测结肠癌。
International advances in surgical oncology Pub Date : 1978-01-01
E D Holyoke, M H Goldrosen
{"title":"Monitoring of colon cancer through measurement of carcinoembroyonic antigen levels, tests of cellular immune competence, and tumor specific immunity.","authors":"E D Holyoke,&nbsp;M H Goldrosen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"85-111"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laser application in gynecologic oncology. 激光在妇科肿瘤中的应用。
International advances in surgical oncology Pub Date : 1978-01-01
H F Schellhas
{"title":"Laser application in gynecologic oncology.","authors":"H F Schellhas","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"237-41"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11756786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical management of malignant tumors of the aerodigestive tract with carbon dioxide laser microsurgery. 二氧化碳激光显微手术治疗气消化道恶性肿瘤。
International advances in surgical oncology Pub Date : 1978-01-01
G J Jako, C W Vaughan, M S Strong, T G Polanyi
{"title":"Surgical management of malignant tumors of the aerodigestive tract with carbon dioxide laser microsurgery.","authors":"G J Jako,&nbsp;C W Vaughan,&nbsp;M S Strong,&nbsp;T G Polanyi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75934,"journal":{"name":"International advances in surgical oncology","volume":"1 ","pages":"265-84"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11341782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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