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IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans最新文献

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Dibenz[a,j]acridine. 二苄基[a，j]吖啶。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.32388/geuhq7
{"title":"Dibenz[a,j]acridine.","authors":"","doi":"10.32388/geuhq7","DOIUrl":"https://doi.org/10.32388/geuhq7","url":null,"abstract":"A yellowish aromatic hydrocarbon consisting of five fused rings formed by the incomplete burning of organic matter. Dibenz[a,j]acridine is primarily found in gasoline exhaust, petroleum refinery incinerator emissions, coal combustion emissions, cigarette smoke and coal tar pitch. T his substance is used only for research purposes. Dibenz[a,j]acridine is reasonably anticipated to be a human carcinogen. (NCI05) Qeios · Definition, February 7, 2020","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"32 1","pages":"283-8"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42270511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Norgestrel. 诺孕酮。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.32388/not5vx
{"title":"Norgestrel.","authors":"","doi":"10.32388/not5vx","DOIUrl":"https://doi.org/10.32388/not5vx","url":null,"abstract":"","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"21 1","pages":"479-90"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49518121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
7H-Dibenzo[c,g]carbazole 7 h-dibenzo (c、g)咔唑
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.32388/p6ckqi
{"title":"7H-Dibenzo[c,g]carbazole","authors":"","doi":"10.32388/p6ckqi","DOIUrl":"https://doi.org/10.32388/p6ckqi","url":null,"abstract":"","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69638968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Chlordecone. 署。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.1016/b0-12-369400-0/00212-x
H. Mehendale, Zhengwei Cai
{"title":"Chlordecone.","authors":"H. Mehendale, Zhengwei Cai","doi":"10.1016/b0-12-369400-0/00212-x","DOIUrl":"https://doi.org/10.1016/b0-12-369400-0/00212-x","url":null,"abstract":"","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"20 1","pages":"67-81"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46016429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Amitrole. 杀草强。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.32388/uv40yx
{"title":"Amitrole.","authors":"","doi":"10.32388/uv40yx","DOIUrl":"https://doi.org/10.32388/uv40yx","url":null,"abstract":"A colorless, odorless crystalline, aromatic amine with a bitter taste. Amitrole is a widely used herbicide for nonfood croplands to control annual and perennial grass type weeds, pondweeds and broad leaf. This substance has a very low acute toxicity in humans and is characterized by skin rash, diarrhea, nausea, vomiting and nose bleeds. Amitrole is reasonably anticipated to be a human carcinogen.","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"41 1","pages":"293-317"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47010181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Mestranol. 炔雌醇甲醚。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.32388/ip33yq
{"title":"Mestranol.","authors":"","doi":"10.32388/ip33yq","DOIUrl":"https://doi.org/10.32388/ip33yq","url":null,"abstract":"\u0000 This monograph on mestranol includes chemical and physical data (synonyms and trade names), structural and molecular formulae and molecular weight of the substance, chemical and physical properties of mestranol, and the production, use, occurrence, and analysis of mestranol. Production of mestranol, which is not known to occur naturally, is synthesis via the reaction of 3-methoxy-1,3,5-oestratrien-17-one with potassium acetylide. All known methods for analyzing mestranol for purity and chemical clarity are summarized tabularly. Biological data relevant to the evaluation of carcinogenic risk to humans of mestranol, which is used mainly in contraceptive preparations, are also presented in brief. Studies of various experimental species and routes of administration led to the conclusion that there is sufficient for the carcinogenicity of mestranol in experimental animals. Data on humans are not available, but it is reasonable to assume mestranol holds potential risk for humans. When mestranol was tested in mice and rats (studies on dogs and monkeys are still in progress) orally in combination with a progestin, it produced pituitary tumors and vaginal and cervical squamous cell carcinomas. Increased incidence of mammary tumors was also noted in both males and females of different species. When used alone, mestranol, by the oral route, increased incidences of pituitary tumors in both sexes, mammary tumors in castrated males, and mammary tumors in females of another mouse species. Mestranol is embryolethal for pre- and postimplantation embryos in some species.\u0000","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"21 1","pages":"257-78"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45276662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Attapulgite. 凹凸棒石。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.32388/df1p70
X. P. Brannmjk
{"title":"Attapulgite.","authors":"X. P. Brannmjk","doi":"10.32388/df1p70","DOIUrl":"https://doi.org/10.32388/df1p70","url":null,"abstract":"","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"42 1","pages":"159-73"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42461350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Benzo[b]fluoranthene. 苯并[b]荧蒽。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.32388/n3rsj9
{"title":"Benzo[b]fluoranthene.","authors":"","doi":"10.32388/n3rsj9","DOIUrl":"https://doi.org/10.32388/n3rsj9","url":null,"abstract":"A colorless, aromatic hydrocarbon consisting of five fused rings and formed by the incomplete burning of organic matter. Benzo(b)fluoranthene is primarily found in gasoline exhaust, tobacco and cigarette smoke, coal tar, soot, amino acids and fatty acid pyrolysis products. T his substance is used only for research purposes. Benzo(b)fluoranthene is reasonably anticipated to be a human carcinogen. (NCI05) Qeios · Definition, February 7, 2020","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"32 1","pages":"147-53"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47785980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dibenzo[a,i]pyrene. 二苯并[a，i]芘。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.32388/vbqo0v
{"title":"Dibenzo[a,i]pyrene.","authors":"","doi":"10.32388/vbqo0v","DOIUrl":"https://doi.org/10.32388/vbqo0v","url":null,"abstract":"hydrocarbon of six rings incomplete organic primarily in tar. reasonably to human carcinogen.","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"32 1","pages":"337-42"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48562341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Styrene oxide. 氧化苯乙烯。
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans Pub Date : 2020-02-07 DOI: 10.15227/orgsyn.008.0102
{"title":"Styrene oxide.","authors":"","doi":"10.15227/orgsyn.008.0102","DOIUrl":"https://doi.org/10.15227/orgsyn.008.0102","url":null,"abstract":"","PeriodicalId":75918,"journal":{"name":"IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans","volume":"19 1","pages":"275-83"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49504815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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