Hospital & community psychiatry最新文献_第2页

Adjunctive trazodone in the treatment of negative symptoms of schizophrenia. 辅助曲唑酮治疗精神分裂症阴性症状。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1220

P Decina, S Mukherjee, V Bocola, F Saraceni, C Hadjichristos, P Scapicchio

{"title":"Adjunctive trazodone in the treatment of negative symptoms of schizophrenia.","authors":"P Decina, S Mukherjee, V Bocola, F Saraceni, C Hadjichristos, P Scapicchio","doi":"10.1176/ps.45.12.1220","DOIUrl":"https://doi.org/10.1176/ps.45.12.1220","url":null,"abstract":"Objective: The study examined whether adjunctive treatment with trazodone would reduce negative symptomatology in patients with chronic, residual schizophrenia.Methods: Patients selected for the study had an established clinical diagnosis of chronic schizophrenia with stable symptomatology, an absence of florid psychotic symptons, a stable regimen of neuroleptic medication, and an absence of depressive disorder. Active psychotic symptoms were assessed using the Brief Psychiatric Rating Scale (BPRS) score on the thinking disturbance factor. Negative symptoms were assessed using the BPRS withdrawal retardation factor as well as the affective flattening and alogia subscales from the Scale for Assessment of Negative Symptoms. Forty-nine patients were randomly assigned to either trazodone or placebo in a six-week double-blind trial.Results: Forty-seven patients, 23 men and 24 women with an average age of 60 years, completed the six-week trial. Twenty-six of the patients received trazodone. Adjunctive treatment with trazodone significantly reduced the severity ratings on two of three measures of negative symptoms and did not significantly increase the severity of positive symptoms; however, the magnitude of the therapeutic effect was modest. The scores for negative symptoms were reduced by approximately 10 to 15 percent, and only three of the 26 actively treated patients showed moderate clinical improvement.Conclusions: Trazodone, used in conjunction with neuroleptics, mildly reduces the severity of negative symptoms in residual schizophrenia and does not exacerbate florid psychosis. The potential benefits of adjunctive trazodone therapy may outweigh the risk of worsening psychosis.","PeriodicalId":75910,"journal":{"name":"Hospital & community psychiatry","volume":"45 12","pages":"1220-3"},"PeriodicalIF":0.0,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/ps.45.12.1220","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18867114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Changing roles of mental health clinicians in multidisciplinary teams. 心理健康临床医生在多学科团队中的角色变化。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1187

J M Schuster, E E Kern, V Kane, L Nettleman

引用次数: 9

Rehabilitation psychiatry in the inpatient treatment of a woman with paranoid schizophrenia. 康复精神病学在住院治疗偏执型精神分裂症的妇女。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1179

T E Smith, A M Woo-Ming, E Lang, L DeFelice, P J Wilner

引用次数: 1

Prevention of recurrent postpartum major depression. 预防产后复发性重度抑郁症。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1191

K L Wisner, S B Wheeler

{"title":"Prevention of recurrent postpartum major depression.","authors":"K L Wisner, S B Wheeler","doi":"10.1176/ps.45.12.1191","DOIUrl":"https://doi.org/10.1176/ps.45.12.1191","url":null,"abstract":"Objective: Postpartum depression affects between 10 and 15 percent of new mothers. These mothers are apprehensive about recurrence after later births. This study tested the efficacy of antidepressant medication administered during the postpartum period to prevent a recurrence of postpartum depression among women who had suffered a previous episode.Methods: An open clinical trial was conducted at a university-based outpatient clinic treating pregnant and postpartum women with mood disorders. Study participants were 23 pregnant women who had at least one previous postpartum episode that fit DSM-III-R criteria for nonbipolar major depression without psychotic features. Postpartum monitoring for recurrence of depressive symptoms was compared with postpartum monitoring plus postbirth treatment with either the medication that had been effective for the previous episode or nortriptyline. The first dose was given within 24 hours of birth. The authors assessed recurrence of postpartum major depression by psychiatric examination and use of the Inventory to Diagnose Depression, a reliable self-report instrument.Results: A significantly greater proportion of the women who elected monitoring alone (62.5 percent) suffered recurrence of major depression compared with the women who received monitoring plus medication (6.7 percent) (p = .0086).Conclusions: Prophylactic antidepressant treatment reduced the recurrence of postpartum major depression.","PeriodicalId":75910,"journal":{"name":"Hospital & community psychiatry","volume":"45 12","pages":"1191-6"},"PeriodicalIF":0.0,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/ps.45.12.1191","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18867130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 126

The early case for caring for the insane in general hospitals. 在综合医院照顾精神病患者的早期案例。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1224

J Walkup

引用次数: 4

An inpatient team's response to alleged sexual misconduct by an outpatient psychotherapist. 住院团队对门诊心理治疗师涉嫌性行为不端的回应。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1231

K P Pages, P E Maxim, H Wasch

引用次数: 2

How to treat inpatients. 如何治疗住院病人。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1239

B Blaska

引用次数: 0

Historical development of legal protection for the rights of mentally ill persons in France. 法国精神病患者权利法律保护的历史发展。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1211

Y Thoret, S Kantin

引用次数: 5

Definitive treatment of patients with serious mental disorders in an emergency service, Part II. 紧急服务中严重精神障碍患者的明确治疗，第二部分。

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1177

P Forster, J King

引用次数: 17

Hospital & community psychiatry Pub Date : 1994-12-01 DOI: 10.1176/ps.45.12.1233

J H Gilmore, D O Perkins, B A Lindsey

引用次数: 3