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Evolução do grau de incapacidade física e do escore olhos, mãos e pés em casos novos de hanseníase 新麻风病病例的身体残疾程度和眼、手、脚评分的演变
Hansenologia internationalis Pub Date : 2023-09-19 DOI: 10.47878/hi.2023.v48.37331
Camila Ferreira Bomtempo, Stephanie Mara Fernandes Ferrari, Maria Aparecida de Faria Grossi, Sandra Lyon
{"title":"Evolução do grau de incapacidade física e do escore olhos, mãos e pés em casos novos de hanseníase","authors":"Camila Ferreira Bomtempo, Stephanie Mara Fernandes Ferrari, Maria Aparecida de Faria Grossi, Sandra Lyon","doi":"10.47878/hi.2023.v48.37331","DOIUrl":"https://doi.org/10.47878/hi.2023.v48.37331","url":null,"abstract":"Este estudo tem por objetivo avaliar a evolução do grau de incapacidade física e do escore olhos, mãos e pés, do diagnóstico à alta medicamentosa, segundo as variáveis sociodemográficas e clínicas, em pacientes diagnosticados com hanseníase. Trata-se de estudo transversal, baseado na análise de 71 pacientes com diagnóstico de hanseníase, acompanhados no Hospital Eduardo de Menezes, centro de referência em Belo Horizonte, Minas Gerais, Brasil, entre janeiro de 2017 a dezembro de 2020. Foi observado predomínio do sexo feminino (53,5%), média de idade de 46 anos, sendo a maioria procedente de outros municípios do interior de Minas Gerais (54,9%). A forma clínica mais frequente foi a dimorfa (64,8%), classificação operacional multibacilar (84,5%). O grau de incapacidade física 0 foi o mais prevalente no diagnóstico (56,5%) e na alta (53,1%), e em relação ao escore olhos, mãos e pés, houve variação entre 0 e 10 no diagnóstico e entre 0 e 8 na alta. Pelo teste de McNemar foi observado que dentre os pacientes que apresentavam algum grau de incapacidade física no momento do diagnóstico, 30,8% apresentaram ausência de incapacidade na alta. Ao comparar a evolução do grau de incapacidade física de paucibacilares e multibacilares no momento do diagnóstico e da alta, houve manutenção em 59,3% e melhora em 17,2% dos pacientes. Os dados apresentados indicam que muitos pacientes foram tratados tardiamente já apresentando as formas graves e com sequelas, já que o estudo foi desenvolvido em um centro de referência, que atende casos mais complexos e com complicações já instaladas. Os dados sugerem que pacientes assistidos que realizam o tratamento com poliquimioterapia podem ter melhora das incapacidades já instaladas. O mesmo ocorreu com o escore olhos, mãos e pés, que ao final do tratamento instituído houve melhora se comparado com a admissão.","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"180 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135063198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Difficulties in the use of the Ridley and Jopling classification--a morphological analysis]. [使用Ridley和Jopling分类的困难——一种形态学分析]。
Hansenologia internationalis Pub Date : 1989-12-01
R N Fleury
{"title":"[Difficulties in the use of the Ridley and Jopling classification--a morphological analysis].","authors":"R N Fleury","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There are many difficulties in the use of the Ridley & Jopling classification in daily practice. The author identified the morphologic parameters whose variations permit to distinguish the polar types and borderline groups according to Ridley. If we avoid the inconstant histologic alterations we believe that this distinction depends basically on the following parameters: epithelioid cell, granuloma of epithelioid cells, numbers of lymphocytes and number of bacilli. A critical analysis is performed of each of these parameters and the author concludes that they are scarce, and that there are great difficulties for the identification and interpretation of their variations for classification purposes. These difficulties are even more important during the reactional episodes.</p>","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 2","pages":"101-6"},"PeriodicalIF":0.0,"publicationDate":"1989-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13706908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Prevention and treatment of physical disabilities in Hansen's disease in Brazil: study of specific professional risk for the disease]. [巴西汉森病身体残疾的预防和治疗:对该疾病的具体职业风险的研究]。
Hansenologia internationalis Pub Date : 1989-12-01
M Pedroso, A Gonçalves, C R Padovani, R Baccarelli, S de Oliveira
{"title":"[Prevention and treatment of physical disabilities in Hansen's disease in Brazil: study of specific professional risk for the disease].","authors":"M Pedroso,&nbsp;A Gonçalves,&nbsp;C R Padovani,&nbsp;R Baccarelli,&nbsp;S de Oliveira","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As a continuation of the research line related to the insertion of prevention and treatment of physical disability in programs of leprosy control, we present here results related to specific professional risk for the disease based on data obtained in a recent multicenter investigation at the national level in Brazil. In a survey of 416 professionals and 69 health units, 179 patients with different clinical forms of leprosy were surveyed. Using initial and current patient socioprofessional condition (whether economically active or dependent and the different modalities of the two situations) as an indicator of social mobility, the associations were tested using the chi 2 statistical parameter of Pearson. The results revealed statistical significance at the 5% level among the variables investigated both in the first and the second specific determination.</p>","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 2","pages":"112-9"},"PeriodicalIF":0.0,"publicationDate":"1989-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13705304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Efficacy of multidrug therapy in treatment of paucibacillary leprosy patients--preliminary results]. 【多药联合治疗少杆菌性麻风病的疗效——初步结果】。
Hansenologia internationalis Pub Date : 1989-12-01
J C Avelleira, A B Marques, F R Viana, V L de Andrade
{"title":"[Efficacy of multidrug therapy in treatment of paucibacillary leprosy patients--preliminary results].","authors":"J C Avelleira,&nbsp;A B Marques,&nbsp;F R Viana,&nbsp;V L de Andrade","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The efficaciousness evaluation of the polychemotherapics regimens recommended by WHO to the hansenian paucibacillary patients, is carried out mainly by the suitable follow up of patients after therapeutic discharge. The criterion for inclusion of patients as paucibacillary ones is another point of importance. The authors based on the follow up of 66 patients that completed treatment and in the absence of relapses until the moment, advise that together with the clinical classification it should be considered factors like: the Mitsuda test, the number of lesions and the bacilloscopy result.</p>","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 2","pages":"107-11"},"PeriodicalIF":0.0,"publicationDate":"1989-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13705303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hansen's disease in the northern region of Brazil--1986]. [1986年巴西北部地区的汉森病]。
Hansenologia internationalis Pub Date : 1989-12-01
R da S Britto
{"title":"[Hansen's disease in the northern region of Brazil--1986].","authors":"R da S Britto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Some general facts about Hansen's Disease are presented: in the world, in the Americas, in 1986, with the purpose to focalize on the Northern Region of Brazil (Amazon Valley) where an attempt is made to specify, State, the clinical forms in the active registry, the respective coefficients of Prevalence, about the cases detected during the year, by clinical forms and the correspondent Coefficient of Incidence, the age range of less than 15 years, and above 15 years; and to analyze according to the township in the State of Amazonas in a series of 8 years, from 1979 to 1986, the registered cases under control and also without control, the new cases, by clinical form and Coefficient of Incidence, the positive cases among students in the capital and also in the country, and with more details, still by township and by Public Health Registry, in 1986, with the population, new cases, and Coefficient of Incidence, cases of the active registry, cases under control, Coefficient of Incidence, the relationship between patients/inhabitants, cases according to the decreasing intensity as far as the Prevalence and Health Department Regions: all this to give an idea, in detail, inclusive statistics, of the real position of Hansen's Disease in the Northern Region (Amazon Valley), with the highest figures of Prevalence and even of Incidence, in comparison with other Regions of the country, and to stress the grave situation of the endemic proportions of the disease, in Brazil in general and in that Regions, in particular.</p>","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 2","pages":"87-100"},"PeriodicalIF":0.0,"publicationDate":"1989-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13705307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histogenic differentiation of polar tuberculoid granuloma and the "benign" or "malignant" behaviour of hanseniasis. 极性结核样肉芽肿的组织学分化与羊粪病的“良”或“恶性”表现。
Hansenologia internationalis Pub Date : 1989-12-01
J Michalany, N S Michalany
{"title":"Histogenic differentiation of polar tuberculoid granuloma and the \"benign\" or \"malignant\" behaviour of hanseniasis.","authors":"J Michalany,&nbsp;N S Michalany","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Based on a new morphological concept and classification of granulomatous inflammation: the polar granulomas, on the histogenesis of the tuberculoid granuloma of the positive Mitsuda test and on the relationship between the degree of histogenetic differentiation and behaviour of tumors, the Authors concluded that the \"benign\" or \"malignant\" behaviour of hanseniasis depends on the degree of tuberculoid differentiation of the lesions. If the lesion is histologically well differentiated toward a polar tuberculoid granuloma (tuberculoid hanseniasis) it will have a \"benign\" behaviour. On the contrary, if this differentiation is absent (virchowian hanseniasis) or poor (interpolar borderline hanseniasis) the behaviour of the lesion will be \"malignant\".</p>","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 2","pages":"83-6"},"PeriodicalIF":0.0,"publicationDate":"1989-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13705306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Myocardial disease, heart failure and reactional tuberculoid leprosy]. [心肌疾病、心力衰竭和反应性结核样麻风病]。
Hansenologia internationalis Pub Date : 1989-12-01
D V Opromolla, R N Fleury
{"title":"[Myocardial disease, heart failure and reactional tuberculoid leprosy].","authors":"D V Opromolla,&nbsp;R N Fleury","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 60-year-old woman was admitted with congestive heart failure, essential hypertension and abdominal distension. Her son reported that she appeared with red spots in the body and that she was under dapsone therapy. Seven months ago there was sudden increase of the skin lesions. In the 11th day after admission she underwent a stroke that progressed to decerebration and she expired on the fourth day. Autopsy confirmed CHF due to chronic myocarditis related to Chagas' disease. Aneurysm of the apical region of the left ventricular chamber was also observed leading to thrombosis and systemic embolism with brain and spleen hemorrhagic infarct. In the encephalous there was edema, uncus herniation and hemorrhagic infarct of the brain stem. The skin lesions were due to reactional tuberculoid hanseniasis (RHT) with focal lesions in axillary lymphnodes, nasopharyngeal mucosa and in the posterior tibial nerve. The pathogenesis of RHT is discussed as well as its differentiation with the BT group of Ridley and Jopling and its probably relationship with the secondary tuberculoid hanseniasis reported by Ridley. The focal lesions are also discussed with END to the involvement of a peripheral nerve trunk what is said to be uncommon in this form of Hansen's disease.</p>","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 2","pages":"120-8"},"PeriodicalIF":0.0,"publicationDate":"1989-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13705305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An induction of the late hypersensitivity reaction to DNCB in patients with different clinical forms of hanseniasis in Brazil. 巴西不同临床形式的麻风病患者对DNCB晚期超敏反应的诱导。
Hansenologia internationalis Pub Date : 1989-06-01
R D Azulay
{"title":"An induction of the late hypersensitivity reaction to DNCB in patients with different clinical forms of hanseniasis in Brazil.","authors":"R D Azulay","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One hundred and twenty Brazilian patients with several forms of hanseniasis were tested with DNCB. The results were the following: 1) the sensitization of patients with hanseniasis to DNCB was lower than that seen in the general population; 2) the sensitization of the borderline and virchowian forms of hanseniasis were lower than that seen in the indeterminate and tuberculoid forms.</p>","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 1","pages":"3-5"},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13638161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New approach to curb the transmission of leprosy. 遏制麻风病传播的新方法。
Hansenologia internationalis Pub Date : 1989-06-01
M C Prabhakar, A V Rao, D R Krishna, T V Ramanakar, P G Rao, K N Reddy
{"title":"New approach to curb the transmission of leprosy.","authors":"M C Prabhakar,&nbsp;A V Rao,&nbsp;D R Krishna,&nbsp;T V Ramanakar,&nbsp;P G Rao,&nbsp;K N Reddy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of local treatment of nose of lepromatous type of patients with different formulations of rifampicin nasal drops/sprays was investigated in a large number of patients. The preparations were either sprayed or instilled into the nostrils after flushing the nostrils with normal saline at 37 degrees C. It was observed that 10 mg/ml of rifampicin was effective in reducing the BI and MI to zero in nose in seven days in majority of the patients. No untoward effect was seen in any of the patients. It is suggested that nasal sprays/drops may be able to prevent the transmission of hanseniasis, as nose is recognised to be an important portal of exit of M. leprae. Further when rifampicin drops/sprays are used as soon as the diagnosis is made, the nasal deformity may be prevented. It is believed that local treatment along with systemic therapy would go a long way in controlling the transmission of hanseniasis.</p>","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 1","pages":"6-13"},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13638164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
About bioresistance, comparative chemoresistance and sulfono resistance of M. leprae. 麻风分枝杆菌的生物耐药、比较化学耐药和磺胺类耐药。
Hansenologia internationalis Pub Date : 1989-06-01
H A Floch
{"title":"About bioresistance, comparative chemoresistance and sulfono resistance of M. leprae.","authors":"H A Floch","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75893,"journal":{"name":"Hansenologia internationalis","volume":"14 1","pages":"46-9"},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13638163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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