G.E.N Pub Date : 1995-01-01

L J Marsicano, M L Berrizbeitia, A Mondelo

{"title":"[Use of glucomannan dietary fiber in changes in intestinal habit].","authors":"L J Marsicano, M L Berrizbeitia, A Mondelo","doi":"","DOIUrl":"","url":null,"abstract":"It has been proven that fiber is effective in the treatment of multiple nosological entities, specially of the colonic pathology. In the present study, two dose of Glucomannan (3 gr/day and 4 gr/day) were evaluated within the modification of the intestinal habit and stool characteristics. 60 patients were included in a random, parallel, double blind, cross over trial study versus placebo. The modification of the intestinal habit was evaluated through variations of daily and weekly evacuations, appraising the stool's consistency and size, satiety after meals tiresomeness between meals, constipation, diarrhea and flatulence. An increase in the number of daily and weekly evacuations during the Glucomannan vs placebo treatment was appreciated and, between the two dose of Glucomannan, a difference was observed as to the large the dose, the large the number of daily and weekly evacuations. Evacuations during the phase of Glucomannan 3 gr/day increased 0.5 times per day, 3 more per week above baseline values. On the 4 gr/day treatment of Glucomannan evacuations increased 0.9 times per day, 6 more per week above baseline values. Patient during the placebo period presented no statistically significant different. No difference was appreciated as to post-meal satiety, nor tiresomeness between meals, possibly due to treatment periods being 5 weeks long. No larger number of cases with diarrhea or flatulence were appreciated with the use of Glucomannan. Glucomannan proved to be superior to placebo, and the 3 gr/day and 4 gr/day doses turned out to beneficial in the improvement of the assessed parameters--better results were obtained using 4 gr/day of Glucomannan than 3 gr/day.","PeriodicalId":75872,"journal":{"name":"G.E.N","volume":"49 1","pages":"7-14"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19546713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Endoscopic retrograde cholangiopancreatography in hepatic fascioliasis]. [内镜逆行胰胆管造影在肝筋膜吸虫病中的应用]。

G.E.N Pub Date : 1994-10-01

C Tombazzi, S Abdul Hadi, V Lecuna, R Contreras, D Marquez

引用次数: 0

[Long term study of the treatment with recombinant alfa 2b interferon in chronic active hepatitis due to B virus in children and adolescents]. [重组α - 2b干扰素治疗儿童和青少年乙型肝炎慢性活动性的长期研究]。

G.E.N Pub Date : 1994-10-01

C Castañeda Guillot, M D Escobar Capote, E García Bacallao, E Borbolla Bousquets

{"title":"[Long term study of the treatment with recombinant alfa 2b interferon in chronic active hepatitis due to B virus in children and adolescents].","authors":"C Castañeda Guillot, M D Escobar Capote, E García Bacallao, E Borbolla Bousquets","doi":"","DOIUrl":"","url":null,"abstract":"To assess the efficacy of recombinant alfa 2b-interferon treatment \"Heberon alfa R\" in children with chronic active hepatitis (CAH) B virus, we conducted a long-term study (three years) in 22 children infected with hepatitis B virus (17 males and 5 females), age range 3 to 15 years. Diagnostic criteria included the clinical picture, laboratory tests, virus markers (HBeAg, HBsAg), laparoscopy and liver biopsy. Children under 12 years received 3 million IU of interferon per day whereas those older than 12 years received 6 million IU of interferon per day by intramuscular injection, three times per week for four months. Alanine aminotransferase (ALT) levels had been elevated for six months in all patients and hepatitis B viral infection was replicative. A variance analysis was made to evaluate ALT response to interferon administration and the Mc Nemar test was used to analyze HBeAg/anti-HBe behavior. Seventeen (77%) out of 22 patients responded to treatment (clearance of HBeAg and ALT levels returned to normal. HBeAg seroconversion (anti-HBe) occurred in 36% of patients during the first year (p < 0.01) and it increased to 50% by the third year follow-up. ALAT levels also decreased and the difference was statistically significant (p < 0.01). This occurred during and after treatment with a steady and increasing tendency to return to normal levels within the first and third year. Side effects were scarce, transient and tolerable and they only appeared during the initial phase of treatment; symptoms were mainly influenza-like and they disappeared very soon. There were no late side effects such as medullar depression, renal toxicity and glycemia alterations.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":75872,"journal":{"name":"G.E.N","volume":"48 4","pages":"219-25"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Macroscopic and histopathological aspects of atypical gastric epithelium]. [非典型胃上皮的宏观和组织病理学方面]。

G.E.N Pub Date : 1994-10-01

D Castro, E Cano, S Peraza, W Oliver, V Sánchez, O Andrade, G López, R García, J Vivas

引用次数: 0

[Complications of laparoscopic cholecystectomy]. [腹腔镜胆囊切除术并发症]。

G.E.N Pub Date : 1994-10-01

C Tombazzi, B Lander, R Bacalao, D Marquez, V Lecuna

{"title":"[Complications of laparoscopic cholecystectomy].","authors":"C Tombazzi, B Lander, R Bacalao, D Marquez, V Lecuna","doi":"","DOIUrl":"","url":null,"abstract":"The laparoscopy cholecistectomy is a surgical procedure described in 1987, and it has had an important apogee and it's had substitute to open procedure. Between its advantages is notable, the postoperatory evolution without pain, paralytic ileus and the short time of hospitalization besides the patient can go away the same day in some cases. In Venezuela, the procedure has been received with enthusiasm by the surgeons with prefer this procedure however, there are complications derived in part for the lack of experience in the first cases, but occur non related of the experience. The quantization of the complications is not simple to realize for different reasons. We present twelve complications, two belong to patients intervened in the Hospital Universitario de Caracas and ten belong to patient transferred from other center. The complications were: pseudoaneurism of hepatic artery, hematoma of the wall, cutting of common bile duct, section the right bile duct, abscess of vesicular bed in two cases, retropneumoperitoneum, ascites by biliary fistula and four biloma. The treatment varied in every case and the utilization of radiologic technique with percutaneous drainage were useful in five cases. We conclude: first, this technique is not free of complications. Second, the percutaneous drainage (abscess, biloma), endoscopic procedure (biliary prosthesis) in fistulaes and arteriographics (arterial embolization), are useful in some cases, and could prevent the surgical reintervention.","PeriodicalId":75872,"journal":{"name":"G.E.N","volume":"48 4","pages":"245-9"},"PeriodicalIF":0.0,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18562861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Intestinal microflora in children with acute and persistent diarrhea]. [儿童急性持续性腹泻的肠道菌群分析]。

G.E.N Pub Date : 1994-10-01

Y García Cristia, T Fragoso Arbelo, M Valdés-Dapena Vivanca, E Sagaro González, N Gorrín Castellanos

引用次数: 0

[Hepatic tolerance of aceclofenac]. [乙酰氯芬酸肝耐受]。

G.E.N Pub Date : 1994-10-01

L J Marsicano, M E Ocampo

引用次数: 0

[Adenosquamous carcinoma of the colon]. [结肠腺鳞癌]。

G.E.N Pub Date : 1994-10-01

N C Betancourt