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The lipase-colipase system as studied with model interfaces. 用模型界面对脂肪酶-裂解酶体系进行了研究。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
C Chapus, M Charles, R Verger, M Sémériva, P Desnuelle
{"title":"The lipase-colipase system as studied with model interfaces.","authors":"C Chapus, M Charles, R Verger, M Sémériva, P Desnuelle","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"182-90"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12075583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The enterohepatic circulation of conjugated bile acids in healthy man: quantitative description and functions. 健康人结合胆汁酸的肠肝循环:定量描述和功能。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
A F Hofmann
{"title":"The enterohepatic circulation of conjugated bile acids in healthy man: quantitative description and functions.","authors":"A F Hofmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A multicompartmental model describing the enterohepatic circulation of conjugated bile acids in man under steady-state conditions is proposed. The model encompasses conjugation; deconjugation and reconjugation; dehydroxylation; sulfation, desulfation and resulfation; dehydrogenation; and stereoselective rehydrogenation. A dynamic description of the enterohepatic circulation and a brief description of bile acid functions in health and dysfunctions in disease are also discussed.</p>","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"69-86"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11541872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies on the effects of hormones on cholesterol synthesis in mammalian cells in culture. 激素对培养的哺乳动物细胞中胆固醇合成影响的研究。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
J Avigan
{"title":"Studies on the effects of hormones on cholesterol synthesis in mammalian cells in culture.","authors":"J Avigan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The studies described here suggest the potential physiological role of polypeptide and corticosteroid hormones in the regulation of cholesterol synthesis. Evidence was shown for substantial differences between various cell types in their responses to these agents and for certain degree of independence of the effects on biosynthesis of cholesterol from those on protein and DNA synthesis. Cholesterol synthesis and HMGCoA reductase are stimulated in a number of diploid cell lines following an incubation with insulin or with glucocorticoids for 4 hr or longer. Stimulation of sterol synthesis by insulin and by dexamethasone requires protein synthesis, but the two hormones do not compete for the same site. Addition of glucagon or of dibutyryl cyclic AMP, or elevation of intracellular cyclic AMP by PGE1 does not inhibit cholesterol synthesis in skin fibroblasts. A possibility of a relationship between the mechanisms of the hormonal effects and of feedback control of cholesterol synthesis is suggested.</p>","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11412895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rat cholesterol as a dynamic system. 大鼠胆固醇是一个动态系统。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
F Chevallier
{"title":"Rat cholesterol as a dynamic system.","authors":"F Chevallier","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"87-113"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11541873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The metabolic lesion in familial hypercholesterolaemia. 家族性高胆固醇血症的代谢损害。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
N B Myant
{"title":"The metabolic lesion in familial hypercholesterolaemia.","authors":"N B Myant","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"39-52"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11413641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of LCAT in cholesterol metabolism. LCAT在胆固醇代谢中的作用。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
J A Glomset, R B Verdery
{"title":"Role of LCAT in cholesterol metabolism.","authors":"J A Glomset,&nbsp;R B Verdery","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"137-42"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11615429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of lipoprotein lipase and capillary endothelium in the clearance of chylomicrons from blood: a model for lipid transport by lateral diffusion in cell membranes. 脂蛋白脂肪酶和毛细血管内皮在血液中乳糜微粒清除中的作用:脂质通过细胞膜侧扩散转运的模型。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
R O Scow, E J Blanchette-Mackie, L C Smith
{"title":"Role of lipoprotein lipase and capillary endothelium in the clearance of chylomicrons from blood: a model for lipid transport by lateral diffusion in cell membranes.","authors":"R O Scow,&nbsp;E J Blanchette-Mackie,&nbsp;L C Smith","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"143-64"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11543132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The activation of lipoprotein lipase by lipase co-protein (apo C-2). 脂肪酶共蛋白(载脂蛋白C-2)对脂蛋白脂肪酶的激活作用。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
C J Fielding, P E Fielding
{"title":"The activation of lipoprotein lipase by lipase co-protein (apo C-2).","authors":"C J Fielding,&nbsp;P E Fielding","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Kinetic analysis of activation of lipoprotein lipase by apo C-2 indicates that the lipase co-protein increase the rate of lipolysis by adsorption to enzyme at the lipid interface, with formation of a 1:1 molar complex, whose dissociation constant in the presence of triglyceride substrate is about 3 X 10(-13) moles cm-3. Activation by apo C-2, like that by the entire lipoprotein apoprotein moiety (Fielding and Fielding, 1976) is reversible by inorganic salts and the dependence of activation on medium ion-pair activity supports the concept that such inhibition is mediated through a single specific anion-binding site of the lipase co-protein.</p>","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"165-72"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11413640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Some aspects of the control of hepatic cholesterol biosynthesis. 控制肝脏胆固醇生物合成的一些方面。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
R G Gould
{"title":"Some aspects of the control of hepatic cholesterol biosynthesis.","authors":"R G Gould","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"13-38"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12075581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regulation of phospholipase A2 activity by different lipid-water interfaces. 不同脂水界面对磷脂酶A2活性的调控。
Exposes annuels de biochimie medicale Pub Date : 1977-01-01
G H De Haas, A J Slotboom, H M Verheij
{"title":"Regulation of phospholipase A2 activity by different lipid-water interfaces.","authors":"G H De Haas,&nbsp;A J Slotboom,&nbsp;H M Verheij","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75842,"journal":{"name":"Exposes annuels de biochimie medicale","volume":"33 ","pages":"191-211"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11242869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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