Current topics in pathology. Ergebnisse der Pathologie最新文献_第9页

Fibrous tumors and tumor-like lesions of childhood: diagnosis, differential diagnosis, and prognosis. 儿童期纤维性肿瘤和肿瘤样病变:诊断、鉴别诊断和预后。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-77289-4_9

D Schmidt

引用次数: 24

Malignant fibrous histiocytoma: a "fibrohistiocytic" or primitive, fibroblastic sarcoma. 恶性纤维组织细胞瘤:一种“纤维组织细胞”或原始纤维母细胞肉瘤。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-77289-4_10

P Meister

引用次数: 11

Malignant peripheral nerve sheath tumours. 恶性周围神经鞘肿瘤。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-77289-4_17

C D Fletcher

引用次数: 59

Atubular glomeruli in chronic renal disease. 慢性肾脏疾病中的小管肾小球。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-79517-6_6

N Marcussen

{"title":"Atubular glomeruli in chronic renal disease.","authors":"N Marcussen","doi":"10.1007/978-3-642-79517-6_6","DOIUrl":"https://doi.org/10.1007/978-3-642-79517-6_6","url":null,"abstract":"The pathological changes in chronic renal failure are heterogeneous and may depend on the primary disease process. Renal function is better correlated with tubular and interstitial changes than with glomerular changes detectable in simple two-dimensional sections. Atubular glomeruli have been demonstrated in many tubulointerstitial disorders. They constitute a significant portion of the glomerular population in some chronic renal diseases. The atubular glomeruli are generally small, but they have open capillaries and minor ultrastructural changes. The number of capillaries is decreased. Glomeruli connected to normal proximal tubules have volumes at the normal level or above. They have not been shown to be eliminated. The presence of atubular glomeruli may explain the correlation between the volume of proximal tubules and the volume of interstitium, on the one hand, and altered renal function on the other. The presence of atubular glomeruli could explain the irreversibility of chronic renal diseases. It is likely that interstitial fibrosis and tubular atrophy in themselves contribute to the decrease in renal function of both glomerular and nonglomerular renal diseases. In glomerular diseases, the glomerular lesion and hyperfiltration may play the major part in the pathogenesis of the deterioration of renal function. The available evidence points toward glomerulo-tubular disconnection as an important and common cause of progression and irreversibility of chronic renal diseases. It provides a simple explanation for the common observation of severely reduced kidney function and mostly normal-looking glomeruli--at least in two dimensions.","PeriodicalId":75767,"journal":{"name":"Current topics in pathology. Ergebnisse der Pathologie","volume":"88 ","pages":"145-74"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-3-642-79517-6_6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18619617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Tubulitis in renal disease. 肾脏疾病中的小管炎。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-79517-6_5

B Iványi, S Olsen

引用次数: 8

Clinical management of soft tissue sarcomas. 软组织肉瘤的临床治疗。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-77289-4_2

J Treuner, M Morgan

引用次数: 11

Molecular biological aspects of soft tissue tumors. 软组织肿瘤的分子生物学研究。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-77289-4_4

T J Triche

引用次数: 8

Selected experimental models of renal tubular atrophy and of cystic tubular cell hyperplasia. 选择肾小管萎缩和囊小管细胞增生的实验模型。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01

H J Gröne

引用次数: 0

Characteristic chromosome abnormalities and karyotype profiles in soft tissue tumors. 软组织肿瘤的特征性染色体异常和核型分析。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-77289-4_5

C Turc-Carel, F Pedeutour, E Durieux

{"title":"Characteristic chromosome abnormalities and karyotype profiles in soft tissue tumors.","authors":"C Turc-Carel, F Pedeutour, E Durieux","doi":"10.1007/978-3-642-77289-4_5","DOIUrl":"https://doi.org/10.1007/978-3-642-77289-4_5","url":null,"abstract":"Characteristic chromosome abnormalities and karyotype profiles are emerging for the soft tissue tumors. The notable findings are summarized in the Table 1. Within the broad range of solid tumors, it is certainly the soft tissue tumors in which the most spectacular success has occurred with regard to neoplasia-associated chromosome abnormalities. Cytogenetic studies of soft tissue tumors have been encouraged by the early and growing supporting interest of pathologists and clinicians concerned with soft tissue tumors. However, when one considers the variety of types and subtypes of benign and malignant soft tissue tumors, the number that has been so far characterized by a specific chromosome change is still very small. But, as we attempt to demonstrate in this report, these data should be viewed as paradigms for the importance of cytogenetic investigations in solid tumors. Cytogenetic studies of solid tumors are of more than clinical interest. Cytogenetic studies allow molecular investigations of the chromosomal breakpoints. They allow the search to proceed for genes involved in the chromosomal changes, providing a better knowledge of the malignant transformation process. In addition, the fruits of the combined efforts in cytogenetic and molecular technologies, from which has come \"molecular cytogenetics,\" will let us recognize more conveniently, more quickly and, hopefully, less expensively the well-characterized diagnostic chromosome markers in tumor cells. Thus, we may be able to reach the goal of incorporating cytogenetics into standard diagnostic procedures for solid tumors, as has been achieved with hematological malignancies. Molecular cytogenetics including fluorescent in situ hybridization (FISH) technology promises to bring soft tissue tumor cytogenetics into regular diagnostic armamentaria and concurrently speed research into the basis of soft tissue tumors.","PeriodicalId":75767,"journal":{"name":"Current topics in pathology. Ergebnisse der Pathologie","volume":"89 ","pages":"73-94"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18883269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

DNA ploidy in soft tissue tumors: an evaluation of the prognostic implications in the different tumor types. 软组织肿瘤的DNA倍体:对不同肿瘤类型的预后影响的评估。

Current topics in pathology. Ergebnisse der Pathologie Pub Date : 1995-01-01 DOI: 10.1007/978-3-642-77289-4_6

W Mellin, A Niezabitowski, M Brockmann, J Ritter, P Wuisman, V Krieg

引用次数: 4