{"title":"Spectral analysis of circadian rhythm data: an application in Acetabularia.","authors":"L Von Lindern, D Mergenhagen, S Berger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75705,"journal":{"name":"Chronobiologia","volume":"20 3-4","pages":"163-7"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19123654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Hodková, I Hodek, G Cornélissen, L K Cutkomp, F Halberg
{"title":"Pyrrhocoris apterus (L.) chronome's response to lighting may reveal changes in rhythms that switch developmental pathways.","authors":"M Hodková, I Hodek, G Cornélissen, L K Cutkomp, F Halberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75705,"journal":{"name":"Chronobiologia","volume":"20 3-4","pages":"251-4"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19123660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A lady and chronobiology.","authors":"B J Kennedy","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75705,"journal":{"name":"Chronobiologia","volume":"20 3-4","pages":"139-44"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19123652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gain in power from chronobiologic designs and analyses.","authors":"V V Fedorov","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75705,"journal":{"name":"Chronobiologia","volume":"20 3-4","pages":"191-2"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19123657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Power of chronobiologic pilots: a statistician's opinion.","authors":"D A Berry","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75705,"journal":{"name":"Chronobiologia","volume":"20 3-4","pages":"213-8"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19123661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChronobiologiaPub Date : 1993-05-01DOI: 10.11239/JSMBE1963.31.SUPPLEMENT_50
R. Hermida
{"title":"Biomedical pattern discrimination of neonatal cardiovascular risk.","authors":"R. Hermida","doi":"10.11239/JSMBE1963.31.SUPPLEMENT_50","DOIUrl":"https://doi.org/10.11239/JSMBE1963.31.SUPPLEMENT_50","url":null,"abstract":"Genetic risk is a primary contributing factor to the predisposition of a newborn child to elevated blood pressure later in life. An index for this factor is needed to assess in the neonate the success or failure of preventive interventions instituted for the pregnant woman. This index could be based on characteristics describing the variability of blood pressure and heart rate during the first days after birth. In the search for such an index, the systolic and diastolic blood pressures and heart rates of 150 newborn babies were automatically monitored at about 30-minute intervals for 48h with a Nippon Colin device, starting early after birth. On the basis of questionnaires given to the parents, the neonates were assigned to a group of either a negative or positive family history of high blood pressure, according to the absence or presence of high blood pressure and/or related cardiovascular disease in two generations (those of the newborn's parents and grandparents). Circadian characteristics and descriptive statistics for the three circulatory variables were used for classification by a so-called \"monotest\", an all-subsets variable selection technique for biomedical discriminant analysis. For a particular combination of variables, the \"monotest\" performs as many steps of separate analyses as the total number of subjects, each subject's data being compared as a set with those of all others (\"leave-one-out\" approach). When the circadian amplitude of systolic blood pressure was used as classifier, the \"monotest\" yielded a 63% classification equivalent to prior criteria, the latter being based on a negative or a positive family history of high blood pressure. The \"monotest\" complements rhythmometric procedures and defines a set of individualized criteria for risk assessment. The combined use of automatic hardware for time-specified sampling with proper software for signal processing and discriminant analysis allows to recognize parameters of blood pressure circadian variability as a source of information for neonatal classification according to cardiovascular disease risk.","PeriodicalId":75705,"journal":{"name":"Chronobiologia","volume":"21 3-4 1","pages":"227-40"},"PeriodicalIF":0.0,"publicationDate":"1993-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64274413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The feedsideward of cephalo-adrenal immune interactions.","authors":"S Sánchez de la Peña","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The feedsideward phenomenon is the interaction of three or more rhythmic physiological entities by a diversified spectrum of rhythms that constitute a rhythmic network. These rhythmic units are: a) the modulator, b) the actor, c) the reactor and d) the integrative unity. Rhythmic interactions are characterized by an alternating sequence of algorithmically predictable effects of attenuation, no effect, and stimulation occurring in different frequencies. The basis of this phenomenon was determined from experimental evidence derived from cephalo-adrenal ex vivo studies. Internal phase-shift studies allow the demonstration ex vivo of a collateral hierarchy of rhythmic neuro-endocrine interactions as alpha, beta, gamma and delta rhythms. Linear least squares analyses describe and quantify circadian (alpha, beta and gamma) and infradian (delta) rhythms in the original series and the differences in responses [beta-alpha] and [gamma-delta]. These spontaneous and response rhythms reveal a collateral neuro-endocrine hierarchy and validate a pineal feedsideward phenomenon. Circadian-infradian murine rhythmic intermodulations are demonstrated in the epithelial corneal mitosis; brain neurosteroids and pineal melatonin content. A circadian rhythm in pineal melatonin content in female B6D2F1 mice and the chronomodulating action of melatonin + ACTH upon adrenal corticosterone production are confirmed. A chronopilot ex vivo study \"suggests\" that melatonin chronomodulates mouse aldosterone production. In a second chronopilot study, HrIL-2 chronomodulates rat corticosterone production ex vivo. Feedsidewards in vivo were seen in the chronomodulation of tumor-host balance occurring after melatonin, IL-2, cefodizime, and cyclosporine treatments that enhanced or delayed tumor growth and survival time of tumor-bearing mice.</p>","PeriodicalId":75705,"journal":{"name":"Chronobiologia","volume":"20 1-2","pages":"1-52"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19340928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationship between activity levels and circadian blood pressure variations.","authors":"I Kohno, H Ishii, T Nakamura, K Tamura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 17 healthy Japanese students (14 males and 3 females) an ambulatory activity level monitoring instrument (Actigraph) was attached to the wrist for 48-hour measurement of wrist movement (with 0.01G or higher acceleration). At the same time, an ambulatory blood pressure monitoring apparatus was attached to these subjects to monitor blood pressure (BP) and heart rate (HR) every 30 minutes. Sleeping hours were calculated from the activity levels. The sleeping hours obtained by the Actigraph correlated with those judged from the diary. The correlation was better for the go-to-sleep time than for the awakening time. Activity level, HR and BP showed a similar circadian variation. Activity level differed significantly between the active daytime (4500 counts/hour) and during sleep at night (720 counts/hour). The acrophase of activity level, obtained by the cosinor method, was 235 degrees which did not significantly differ from that of BP and HR. Hourly activity levels correlated with HR and BP at corresponding hours. These results suggest that BP is affected by activity levels even if this rhythm continues to recur in bedrest.</p>","PeriodicalId":75705,"journal":{"name":"Chronobiologia","volume":"20 1-2","pages":"53-61"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19340929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}