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Experimental barbiturate intoxication: treatment by partial cardiopulmonary bypass and hemodialysis. 实验性巴比妥酸盐中毒:部分体外循环及血液透析治疗。
Cardiovascular Research Center bulletin Pub Date : 1976-01-01
J H Kennedy, J Barnette, A Flasterstein, W Higgs
{"title":"Experimental barbiturate intoxication: treatment by partial cardiopulmonary bypass and hemodialysis.","authors":"J H Kennedy,&nbsp;J Barnette,&nbsp;A Flasterstein,&nbsp;W Higgs","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>1. The results of a series of experiments in which anesthetized mongrel dogs were instrumented and preparations for closed-chest partial cardiopulmonary bypass with membrane oxygenation and hemodialysis were made, following which \"fatal\" barbiturate intoxication was produced by the intravenous route has been presented. 2. Of nine animals, three (33 l/3%) could be removed from cardiopulmonary bypass although postoperative cardiovascular dynamics remained abnormal. 3. The clinical implications of this study in patients with cardiac depression in spite of hemodialysis for barbiturate intoxication seemed promising.</p>","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"14 3","pages":"61-8"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12435088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The importance of cuff width in measurement of blood pressure indirectly. 袖带宽度在间接测量血压中的重要性。
Cardiovascular Research Center bulletin Pub Date : 1976-01-01
L A Geddes, R Tivey
{"title":"The importance of cuff width in measurement of blood pressure indirectly.","authors":"L A Geddes,&nbsp;R Tivey","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Blood pressure was measured indirectly in young adults with arm circumferences ranging from 21 to 35 cm using three standard blood pressure cuffs (thigh, adult, and child). The auscultatory method was used with Phase 1 and Phase V to indicate systolic and diastolic pressures respectively. It was found that use of the narrow cuff provided values higher than those obtained with the adult cuff; use of the thigh cuff produced value lower than those obtained with the adult cuff. These data, and a careful review of the literature, reveal the fundamental nature of the effect of the ratio of cuff width to member circumference with respect to the accuracy of indirect blood pressure measurements. The order of error expected with narrow and wide cuffs is discussed.</p>","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"14 3","pages":"69-79"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12436008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of ketamine on ventricular dynamics of unanesthetized baboons. 氯胺酮对未麻醉狒狒心室动力学的影响。
Cardiovascular Research Center bulletin Pub Date : 1975-10-01
J E Chimoskey, L L Huntsman, E Gams, W J Flanagan
{"title":"Effect of ketamine on ventricular dynamics of unanesthetized baboons.","authors":"J E Chimoskey,&nbsp;L L Huntsman,&nbsp;E Gams,&nbsp;W J Flanagan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ketamine hydrochloride is commonly employed to sedate or anesthetize laboratory primates but its cardiac actions have not been previously described in these animals. Four baboons, Papio cynocephalus, were chronically instrumented with electromagnetic flow detectors on the ascending aorta and common carotid artery. Cardiac output, peak aortic flow velocity and peak aortic flow acceleration are all depressed by Ketamine, 5 mg/kg i.m. Peak aortic flow acceleration and peak carotid flow acceleration were equally depressed. Thus, peak carotid flow acceleration is a useful indirect index of the left ventricular response to Ketamine in the baboon.</p>","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"14 2","pages":"53-7"},"PeriodicalIF":0.0,"publicationDate":"1975-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12388618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The simultaneous comparison of the electrical impedance method for measuring stroke volume and cardiac output with four other methods. 电阻抗法测量脑搏量和心输出量与其他四种方法的同时比较。
Cardiovascular Research Center bulletin Pub Date : 1975-10-01
T D Pate, L E Baker, J P Rosborough
{"title":"The simultaneous comparison of the electrical impedance method for measuring stroke volume and cardiac output with four other methods.","authors":"T D Pate,&nbsp;L E Baker,&nbsp;J P Rosborough","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"14 2","pages":"39-52"},"PeriodicalIF":0.0,"publicationDate":"1975-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11963625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A historical perspective on physiological monitoring: Chauveau's projecting kymograph and the projecting physiograph. 生理监测的历史透视:肖沃的投影式心电图仪和投影式生理仪。
Cardiovascular Research Center bulletin Pub Date : 1975-07-01
H E Hoff, L A Geddes
{"title":"A historical perspective on physiological monitoring: Chauveau's projecting kymograph and the projecting physiograph.","authors":"H E Hoff,&nbsp;L A Geddes","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"14 1","pages":"3-35"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12279940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of the time course of left ventricular wall stress and velocity of fiber shortening in man by simultaneous left ventricular pressure and echocardiographic recording: preliminary report. 通过左心室压力和超声心动图同时记录测定人左室壁应力和纤维缩短速度的时间过程:初步报告。
Cardiovascular Research Center bulletin Pub Date : 1975-04-01
M A Quinones, W H Gaasch, J S Cole, J K Alexander
{"title":"Determination of the time course of left ventricular wall stress and velocity of fiber shortening in man by simultaneous left ventricular pressure and echocardiographic recording: preliminary report.","authors":"M A Quinones,&nbsp;W H Gaasch,&nbsp;J S Cole,&nbsp;J K Alexander","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This report presents a method for determining the time course of circumferential LV wall stress and fiber shortening velocity (endocardial as well as midwall) using simultaneous recordings of LV dimensions by echography and LV pressure (micromanometer). The values for max VCF, VCF at peak stress, mean VCF, and peak stress are in general agreement with those observed with previous methods; the separation between normal and abnormal LV function appears to be good. The method permits frequent observations to be performed in a single patient, which is of particular value during acute interventions. Data from a small number of interventions suggest that VCF in man is relatively insensitive to acute changes in preload, is inversely affected by changes in afterload and appears sensitive to inotropic stimulation. Although VCF seems to be a good index of LV performance, its sensitivity to afterload might, at times, limit its usefulness.</p>","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"13 4","pages":"63-77"},"PeriodicalIF":0.0,"publicationDate":"1975-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12318153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temperature-sensitive hypoxanthine-guanine phosphoribosyltransferase in mutant Chinese hamster cells. 突变体中国仓鼠细胞中温度敏感的次黄嘌呤-鸟嘌呤磷酸核糖基转移酶。
Cardiovascular Research Center bulletin Pub Date : 1975-01-01
R G Fenwick, C T Caskey
{"title":"Temperature-sensitive hypoxanthine-guanine phosphoribosyltransferase in mutant Chinese hamster cells.","authors":"R G Fenwick,&nbsp;C T Caskey","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By selecting variants of Chinese hamster cells that were resistant to 6TG at 39 degrees C, but which would continue to grow in HAT medium at 33 degrees C, we have isolated cell lines with thermosensitive phenotypes for HGPRT controlled properties. THE HGPRT produced by those clones is temperature sensitive. These results indicate that the selected clones carry missense mutations in the structural gene for the enzyme.</p>","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"13 3","pages":"43-51"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12326309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A mathematical model describing the effects of coronary artery stenosis on coronary blood flow in resting and stressed dogs. 描述静息和应激犬冠状动脉狭窄对冠状动脉血流影响的数学模型。
Cardiovascular Research Center bulletin Pub Date : 1975-01-01
D J Lawrie, R A Levinsky, R M Lewis, H K Thompson, J S Cole
{"title":"A mathematical model describing the effects of coronary artery stenosis on coronary blood flow in resting and stressed dogs.","authors":"D J Lawrie,&nbsp;R A Levinsky,&nbsp;R M Lewis,&nbsp;H K Thompson,&nbsp;J S Cole","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"13 3","pages":"52-60"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12326311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A historical perspective on physiological monitoring: Sherrington's mammalian laboratory and its antecedents. 生理监测的历史观点:谢林顿的哺乳动物实验室及其前身。
Cardiovascular Research Center bulletin Pub Date : 1974-10-01
H E Hoff, L A Geddes
{"title":"A historical perspective on physiological monitoring: Sherrington's mammalian laboratory and its antecedents.","authors":"H E Hoff,&nbsp;L A Geddes","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"13 2","pages":"19-39"},"PeriodicalIF":0.0,"publicationDate":"1974-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15718094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recording esophageal heart sounds with a catheter-tip contact microphone. 用导管尖端接触式麦克风记录食道心音。
Cardiovascular Research Center bulletin Pub Date : 1974-07-01
L A Geddes, J D Bourland, E Arriaga
{"title":"Recording esophageal heart sounds with a catheter-tip contact microphone.","authors":"L A Geddes,&nbsp;J D Bourland,&nbsp;E Arriaga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The use of a catheter-tip microphone is described for the detection of heart sounds in the esophagus. The intensity and quality of the sounds differ from those detected on the precordium. Individual valve and breath sounds can be attenuated by choice of the location of the microphone in the esophagus. The acoustic shielding provided by the thorax allows presentation of heart sounds with little difficulty from acoustic feedback.</p>","PeriodicalId":75677,"journal":{"name":"Cardiovascular Research Center bulletin","volume":"13 1","pages":"3-7"},"PeriodicalIF":0.0,"publicationDate":"1974-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15569051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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