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Bulletin on the rheumatic diseases最新文献

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The use of low-dose prednisone in the management of rheumatoid arthritis. 小剂量强的松在类风湿关节炎治疗中的应用。
Bulletin on the rheumatic diseases Pub Date : 2001-01-01
S S Lim, D L Conn
{"title":"The use of low-dose prednisone in the management of rheumatoid arthritis.","authors":"S S Lim,&nbsp;D L Conn","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Low doses of prednisone are safe and effective in the management of RA. Yet, some clinicians continue to manage their RA patients with glucocorticoid doses that are too high or avoid them altogether. Glucocorticoids in low doses have proven to be very effective in suppressing the inflammation associated with RA. In addition, there is good evidence that low doses of prednisolone retard bony erosions of RA. Potential side effects of low doses of glucocorticoids can be anticipated and avoided with prudent preventative measures and appropriate management. Therefore, prednisone should be initiated as early as possible in the treatment of RA usually with another DMARD. Treatment of the inflammation in RA should not exceed 10 mg/day and often may need to be given in daily divided doses (5 mg BID). Supplemental daily calcium at 800-1,000 mg/day and vitamin D at 400-800 units/day should always be initiated with treatment. Tapering of prednisone should be done slowly using 1 mg decrements every couple weeks to a month. One should not deem it a failure to hold the patient on the lowest effective dose of prednisone.</p>","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"50 12","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22071772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensible approach to low back pain. 合理处理腰痛。
Bulletin on the rheumatic diseases Pub Date : 2001-01-01
S M Helfgott
{"title":"Sensible approach to low back pain.","authors":"S M Helfgott","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"50 3","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22071771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on reactive arthritis. 反应性关节炎的最新进展。
Bulletin on the rheumatic diseases Pub Date : 2001-01-01
L H Sigal
{"title":"Update on reactive arthritis.","authors":"L H Sigal","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"50 4","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22071770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Getting to the heart of the matter in systemic lupus and rheumatoid arthritis. 进入系统性狼疮和类风湿性关节炎的核心问题。
Bulletin on the rheumatic diseases Pub Date : 2001-01-01
S Manzi, M C Wasko
{"title":"Getting to the heart of the matter in systemic lupus and rheumatoid arthritis.","authors":"S Manzi,&nbsp;M C Wasko","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"50 5","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22071969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex and arthritis. 性和关节炎。
Bulletin on the rheumatic diseases Pub Date : 2000-07-01
R S Panush, G D Mihailescu, M T Gornisiewicz, S H Sutaria, D J Wallace
{"title":"Sex and arthritis.","authors":"R S Panush,&nbsp;G D Mihailescu,&nbsp;M T Gornisiewicz,&nbsp;S H Sutaria,&nbsp;D J Wallace","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"49 7","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2000-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21948853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adult-onset Still's disease. 成人发病的斯蒂尔氏病。
Bulletin on the rheumatic diseases Pub Date : 2000-01-01
J J Cush
{"title":"Adult-onset Still's disease.","authors":"J J Cush","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"49 6","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21926218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lyme disease and the Lyme disease vaccines. 莱姆病和莱姆病疫苗。
Bulletin on the rheumatic diseases Pub Date : 1999-04-01
L H Sigal
{"title":"Lyme disease and the Lyme disease vaccines.","authors":"L H Sigal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Both OspA vaccines, with or without adjuvant, are effective and safe. People must receive repeated doses of the vaccine, however, to receive effective protection. If the vaccines are to be part of a Lyme disease prevention strategy, doctors and patients must pay attention to booster shot timing. Maximum public health benefit can be achieved only if the Lyme disease vaccines are integrated into broad individual and community-based efforts to prevent Lyme disease and other tick-borne diseases. Only people at significant risk of contracting Lyme disease should consider vaccination, and vaccination should merely complement--not replace--personal precautions for avoiding tick bites.</p>","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"48 4","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21284216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lupus for the non-rheumatologist. 非风湿病专家的狼疮。
Bulletin on the rheumatic diseases Pub Date : 1999-01-01
D J Wallace
{"title":"Lupus for the non-rheumatologist.","authors":"D J Wallace","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"48 9","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21493480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on fibromyalgia syndrome. 纤维肌痛综合征的最新进展。
Bulletin on the rheumatic diseases Pub Date : 1999-01-01
D J Wallace, S Shapiro, R S Panush
{"title":"Update on fibromyalgia syndrome.","authors":"D J Wallace,&nbsp;S Shapiro,&nbsp;R S Panush","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"48 5","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21387832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor necrosis factor inhibitors for rheumatoid arthritis. 类风湿关节炎肿瘤坏死因子抑制剂。
Bulletin on the rheumatic diseases Pub Date : 1999-01-01
R E Jones, L W Moreland
{"title":"Tumor necrosis factor inhibitors for rheumatoid arthritis.","authors":"R E Jones,&nbsp;L W Moreland","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tumor necrosis factor antagonists such as infliximab and etanercept represent a new and powerful approach to managing RA. In studies published to date, TNF antagonists appear to be safe and effective agents for short-term therapeutic use in RA. Defining when in the course of RA to use TNF antagonists and determining the effectiveness of combinations of these biologic agents with DMARDs or other cytokine antagonists are areas of current and future studies. Other cytokine antagonists that may be promising subjects for further study are IL-1 antagonists. Like TNF, IL-1 is a member of the inflammatory cascade, but may play a different role in the development of inflammatory arthritis. In animal models, inhibition of TNF suppressed the inflammatory response while IL-1 antagonism prevented joint destruction (2). These results imply that combination therapy providing inhibition of both IL-1 and TNF might be an effective treatment in humans with RA, but clinical trials in humans have not yet been performed. Studies are underway in people with early RA to determine if the new TNF inhibitors are more effective or safer than currently available therapies, such as methotrexate. Other agents that inhibit TNF activity are also being tested at this time in people with RA.</p>","PeriodicalId":75657,"journal":{"name":"Bulletin on the rheumatic diseases","volume":"48 3","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21274674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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