发布求助
文献互助 智能选刊 最新文献

Bulletin (National Clearinghouse for Poison Control Centers (U.S.))最新文献

筛选
英文 中文
The interleukin-10-1082 G/A polymorphism: allele frequency in different populations and functional significance. 白细胞介素-10-1082 G/A 多态性：不同人群中的等位基因频率及其功能意义。
IF 6.2
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 2002-03-01 DOI: 10.1007/s00018-002-8448-0
L E N Rees, N A P Wood, K M Gillespie, K N Lai, K Gaston, P W Mathieson
{"title":"The interleukin-10-1082 G/A polymorphism: allele frequency in different populations and functional significance.","authors":"L E N Rees, N A P Wood, K M Gillespie, K N Lai, K Gaston, P W Mathieson","doi":"10.1007/s00018-002-8448-0","DOIUrl":"10.1007/s00018-002-8448-0","url":null,"abstract":"<p><p>Genotypic variation in the human interleukin-10 (IL-10) promoter may account for marked inter-individual variation in IL-10 production and may influence susceptibility to autoimmune diseases. The G/A polymorphism at position -1082 has been linked to high/low IL-10 producer status. We directly tested the functional significance of this polymorphism using DNA-binding assays and reporter gene assays, examined allele frequencies in two geographically distinct populations and assessed intra- and inter-individual variation in IL-10 production in vitro according to genotype. Functional analyses showed that the -1082 region contains a putative ETS-like transcription factor-binding site, and nuclear factors from a monocyte cell line bind to this region. Transient transfection studies in an Epstein-Barr virus-transformed B cell line indicated that the -1082 A allele confers a two fold increase in transcriptional activity of the IL-10 promoter compared to the G allele. There was marked inter-individual variation in IL-10 production by peripheral blood mononuclear cells in vitro, with no consistent effect of genotype.</p>","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"1 1","pages":"560-9"},"PeriodicalIF":6.2,"publicationDate":"2002-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11337416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79657954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accidental poisoning of children by veterinary drugs. 儿童因兽药意外中毒。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1982-04-01
N W Glickman, L T Glickman, L S Rivkin
{"title":"Accidental poisoning of children by veterinary drugs.","authors":"N W Glickman,&nbsp;L T Glickman,&nbsp;L S Rivkin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"26 2","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"1982-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18147044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
1980 survey of poison control centers. 1980年毒物控制中心调查。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1982-01-01
J H Schaeffer, S J Lavengood
{"title":"1980 survey of poison control centers.","authors":"J H Schaeffer,&nbsp;S J Lavengood","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"26 1","pages":"2-10"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18105076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silica flour: silicosis. 二氧化硅粉:矽肺病。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1981-10-01
{"title":"Silica flour: silicosis.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"25 7","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"1981-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18303277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Poisoning mortality in the United States, 1978. 1978年美国的中毒死亡率。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1981-08-01
D A Brancato, M I Fow
{"title":"Poisoning mortality in the United States, 1978.","authors":"D A Brancato,&nbsp;M I Fow","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"25 6","pages":"11-5"},"PeriodicalIF":0.0,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18314111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gasoline exposure accidents. 汽油暴露事故。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1981-08-01
M I Fow
{"title":"Gasoline exposure accidents.","authors":"M I Fow","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"25 6","pages":"20"},"PeriodicalIF":0.0,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18314114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tabulations of 1979 poison control case reports. 1979年中毒控制病例报告表。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1981-08-01
M I Fow
{"title":"Tabulations of 1979 poison control case reports.","authors":"M I Fow","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"25 6","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18314110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amphetamine look-alikes. 安非他命的小伎俩。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1981-08-01
N Newburn
{"title":"Amphetamine look-alikes.","authors":"N Newburn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"25 6","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18314113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phenylpropanolamine weight control products. 苯丙醇胺重量控制产品。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1981-08-01
D A Brancato, B I Cohen, M I Fow
{"title":"Phenylpropanolamine weight control products.","authors":"D A Brancato,&nbsp;B I Cohen,&nbsp;M I Fow","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"25 6","pages":"16-8"},"PeriodicalIF":0.0,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18314112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes planned for clearinghouse program. 计划更改票据交换所程序。
Bulletin (National Clearinghouse for Poison Control Centers (U.S.)) Pub Date : 1981-06-01
{"title":"Changes planned for clearinghouse program.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75631,"journal":{"name":"Bulletin (National Clearinghouse for Poison Control Centers (U.S.))","volume":"25 5","pages":"2-4"},"PeriodicalIF":0.0,"publicationDate":"1981-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18357011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信