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Boletin de estudios medicos y biologicos最新文献

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Effects of quipazine in evoked potentials recorded in the cingulum of the cat. 喹帕嗪对猫扣带诱发电位记录的影响。
Boletin de estudios medicos y biologicos Pub Date : 1989-01-01
C M Contreras, M L Marván
{"title":"Effects of quipazine in evoked potentials recorded in the cingulum of the cat.","authors":"C M Contreras,&nbsp;M L Marván","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present study describes the changes in electroencephalogram (EEG), behavior, and visual evoked potentials (VEPs) recorded in some structures of the limbic system of freely moving cats which had been administered two different doses of quipazine through different routes (5 mg/kg i.p. and 10 mg/kg i.v.). After the low dose of quipazine, the EEG from the cingulum developed a 6 c/s spike and wave activity. The amplitude of the P150 component of VEPs in the cingulum recording increased, while the VEPs recorded in visual cortex were barely affected. Simultaneously the animals displayed exploratory movements towards objects undetected by observers. The changes found in the cingulum with the tested doses may be due to specific actions of the drug on the polysensorial pathways. The high dose produced a rage reaction accompanied by a generalized spiking, intermixed with high voltage-low frequency waves, and an increase in VEPs in all recorded structures. At high doses the drug may be producing a discordance between the sensorial pathways and those in charge of the emotional processes.</p>","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"37 1-2","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13673922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of thyroxine on the development of self-grooming behavior in rats. 甲状腺素对大鼠自我梳理行为发展的影响。
Boletin de estudios medicos y biologicos Pub Date : 1989-01-01
M Salas, S Pulido, C Torrero, C Escobar
{"title":"Effects of thyroxine on the development of self-grooming behavior in rats.","authors":"M Salas,&nbsp;S Pulido,&nbsp;C Torrero,&nbsp;C Escobar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of intraperitoneal thyroxine administration (1 microgram/body weight) on postnatal days 1-3 and the subsequent alterations upon the development of six self-grooming components were measured postnatally in male Wistar rats between days 1-60. Observations on self-grooming components showed that thyroxine-treated rats did not show consistent significant differences in the duration of grooming movements of short displacement directed to the forepaws and head throughout the study, as compared to controls. By contrast, after weaning, the duration of grooming movements of long displacement directed to the fur, genital area, and body scratching were significantly increased. The findings suggest that early thyroxine treatment may primarily interfere with the neural circuitry that modulate long displacement grooming movements, rather than with the substrates controlling short displacement grooming activities. Thus, the hormone might be acting upon neural modulatory systems of self-grooming having different vulnerability in relation to the level of maturity of the brain circuits underlying each grooming component.</p>","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"37 1-2","pages":"3-10"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13941305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modifications of acoustic habituation by interruption of visual input in quipazine treated cats. 通过中断视觉输入在喹帕嗪治疗猫的听觉习惯的改变。
Boletin de estudios medicos y biologicos Pub Date : 1989-01-01
M Cervantes, C Guzmán-Flores
{"title":"Modifications of acoustic habituation by interruption of visual input in quipazine treated cats.","authors":"M Cervantes,&nbsp;C Guzmán-Flores","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of interruption of the visual input on acoustic habituation was studied in cats before and following the administration of quipazine, 3 mg/kg iv. The characteristics of acoustic habituation were analyzed through the magnitude and temporal course of multiunit activity (MUA) responses elicited in the mesencephalic reticular formation (MRF) by repetitive acoustic stimuli (70 db, 50 Hz trains of 2 sec duration) in 6 freely moving cats with cortical electrodes over the parietal cortex and bipolar electrodes chronically implanted in MRF and basolateral amygdala (AMN). The cats were submitted to repetitive acoustic stimulation during one 30 min period before, and three 30 min periods after drug administration in the following conditions: a) with unmasked eyes; b) with masked eyes by means of dark contact lenses. Persistent attentive behavior, catatonic attitudes, hypersynchronous (6 Hz, 100-150 microV) EEG activity and significant increase of spontaneous MUA in FRM and AMN were induced by quipazine both in the cats tested with unmasked and with masked eyes. This increase of MUA was higher immediately following drug administration and progressively decreased, although MUA values remained significantly higher than controls 110 min after quipazine administration. Acoustic habituation, evidenced through the progressive decrease of MUA responses of MRF to acoustic stimuli, was observed before quipazine administration when the cats were tested with unmasked and with masked eyes; as well as in cats tested with unmasked eyes following drug administration. However, the MUA responses to acoustic stimuli did not decrease in cats with masked eyes during acoustic stimulation periods 0-30 min and 40-70 min after quipazine administration.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"37 1-2","pages":"28-35"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13941303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double cortical control acting upon activities of intralaminar thalamic cells. 双皮质控制作用于丘脑层内细胞的活动。
Boletin de estudios medicos y biologicos Pub Date : 1989-01-01
M Condés-Lara, M León-Olea, M Sánchez-Alvarez, I Omaña-Zapata
{"title":"Double cortical control acting upon activities of intralaminar thalamic cells.","authors":"M Condés-Lara,&nbsp;M León-Olea,&nbsp;M Sánchez-Alvarez,&nbsp;I Omaña-Zapata","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report the effects exerted by the cortex upon the intralaminar thalamic nucleic, as revealed by reversible blockade of the cortex with spreading depression in awake rats. Extracellular recordings of spontaneous activity were made simultaneously at thalamic and cortical sites. The effect of peripheral receptive field stimulation was to decrease activity of intralaminar thalamic cells. Cortical recordings revealed the cortical regions affected by spreading depression. Two type of cells were identified depending on the changes in their sensorial responses during the cortical spreading depression propagation. The first exhibited a tonic facilitating cortical control when the cortical spreading depression was located at A 8.0 to A 10.0. The second type exhibited a disappearance of the sensorial responses when cortical spreading depression was located at A 4.0 to A 8.0 and also displayed the tonic facilitating control. This indicates that two different identified cortical regions influenced the thalamic activity.</p>","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"37 1-2","pages":"63-8"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13942471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antigen-induced antigen endocytosis in primitive reticular cells of connective tissue of innervated and denervated skeletal muscle from the allergized guinea pig. 过敏豚鼠神经支配和去神经支配骨骼肌结缔组织原始网状细胞抗原诱导的抗原内吞作用。
Boletin de estudios medicos y biologicos Pub Date : 1989-01-01
F Alonso-deFlorida, A Gutiérrez López, H Merchant-Larios
{"title":"Antigen-induced antigen endocytosis in primitive reticular cells of connective tissue of innervated and denervated skeletal muscle from the allergized guinea pig.","authors":"F Alonso-deFlorida,&nbsp;A Gutiérrez López,&nbsp;H Merchant-Larios","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Electron microscope studies demonstrated that soluble proteins (ferritin and horseradish peroxidase) administered in vitro to strips of guinea pig diaphragmatic muscle under physiological conditions were internalized by vesicles of primitive reticular cells (PRCs) found in the connective tissue. This endocytosis effect was enhanced when the muscle preparations were obtained from animals actively allergized to the protein. Denervation increased the occurrence of peroxidase-positive vesicles in the peroxidase-antiperoxidase system. These results suggest that the antigen-antibody interaction induces endocytosis directed to the specific antigen.</p>","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"37 1-2","pages":"36-41"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13941307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Localization of the microelectrode tip combining a rapid procedure method and marking with pontamine sky blue. 结合快速程序法和波胺天蓝标记的微电极尖端定位。
Boletin de estudios medicos y biologicos Pub Date : 1988-01-01
M Sánchez-Alvarez, M León-Olea, M Condés-Lara, M Briones, A Fernández-Guardiola
{"title":"Localization of the microelectrode tip combining a rapid procedure method and marking with pontamine sky blue.","authors":"M Sánchez-Alvarez,&nbsp;M León-Olea,&nbsp;M Condés-Lara,&nbsp;M Briones,&nbsp;A Fernández-Guardiola","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"36 1-4","pages":"55-9"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13611797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diazepam induced long term delay in the migration of external granular layer of the cerebellum: an experimental study in the mouse. 安定对小鼠小脑外颗粒层迁移的长期延缓作用的实验研究。
Boletin de estudios medicos y biologicos Pub Date : 1988-01-01
M C Márquez-Orozco, A Márquez-Orozco, A Escobar
{"title":"Diazepam induced long term delay in the migration of external granular layer of the cerebellum: an experimental study in the mouse.","authors":"M C Márquez-Orozco,&nbsp;A Márquez-Orozco,&nbsp;A Escobar","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"36 1-4","pages":"19-24"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14360930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibody targeting in vivo: binding of anti-DNP antibodies to implanted silk-DNP as a model of specific antibodies binding to localized antigens. 体内抗体靶向:抗dnp抗体与植入蚕丝的结合——dnp作为特异性抗体与局部抗原结合的模型。
Boletin de estudios medicos y biologicos Pub Date : 1988-01-01
V Yakoleff, C Larralde
{"title":"Antibody targeting in vivo: binding of anti-DNP antibodies to implanted silk-DNP as a model of specific antibodies binding to localized antigens.","authors":"V Yakoleff,&nbsp;C Larralde","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"36 1-4","pages":"43-53"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14360934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomical study of the wulst in the parakeet (Aratinga canalicularis). 长尾小鹦鹉(Aratinga canalicularis)毛的解剖学研究。
Boletin de estudios medicos y biologicos Pub Date : 1988-01-01
S Diaz-Cintra, L Cintra, A Ortega, B Pérez, F Ayala
{"title":"Anatomical study of the wulst in the parakeet (Aratinga canalicularis).","authors":"S Diaz-Cintra,&nbsp;L Cintra,&nbsp;A Ortega,&nbsp;B Pérez,&nbsp;F Ayala","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"36 1-4","pages":"25-34"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14360931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of nickel chloride on bone marrow of iron-deficient rats. 氯化镍对缺铁大鼠骨髓的影响。
Boletin de estudios medicos y biologicos Pub Date : 1988-01-01
E L Novelli, N L Rodrigues, B O Ribas
{"title":"Influence of nickel chloride on bone marrow of iron-deficient rats.","authors":"E L Novelli,&nbsp;N L Rodrigues,&nbsp;B O Ribas","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"36 1-4","pages":"35-42"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14360933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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