Boletin de estudios medicos y biologicos最新文献_第2页

Increased oxygen radical and high-dietary-carbohydrate pancreatic damage. 氧自由基增加和高饮食碳水化合物胰腺损伤。

Boletin de estudios medicos y biologicos Pub Date : 1994-01-01

E L Novelli, J L Novelli Filho, N L Rodrigues, B O Ribas

引用次数: 0

Preliminary characterization of epithelial root sheath cells in vitro. 上皮根鞘细胞体外初步鉴定。

Boletin de estudios medicos y biologicos Pub Date : 1994-01-01

H Arzate

引用次数: 0

New electrophysiological approaches to the suprachiasmatic circadian pacemaker. 视交叉上昼夜节律起搏器的新电生理学方法。

Boletin de estudios medicos y biologicos Pub Date : 1994-01-01

L Zhang

引用次数: 0

Distribution of mast cells in the tracheal tissue components of the guinea pig and its bearing on the Schultz-Dale reaction. 豚鼠气管组织成分中肥大细胞的分布及其与舒尔茨-戴尔反应的关系。

Boletin de estudios medicos y biologicos Pub Date : 1994-01-01

G Sánchez-Mejorada, F Alonso-de-Florida

引用次数: 0

Alterations in the thalamic reticular nucleus of rats neonatally treated with thyroxine. 甲状腺素对新生大鼠丘脑网状核的影响。

Boletin de estudios medicos y biologicos Pub Date : 1993-01-01

M Salas, C Torrero, M Regalado, P Carrillo

引用次数: 0

Modulated intra-train spike responses in the cat superior cervical ganglion in vivo. 猫颈上神经节体内调节的训练内尖峰反应。

Boletin de estudios medicos y biologicos Pub Date : 1993-01-01

M A Morales, F Alonso-de-Florida

引用次数: 0

Monoamine metabolites in normal human cerebrospinal fluid and in degenerative diseases of the central nervous system. 正常人脑脊液和中枢神经系统退行性疾病中的单胺代谢物。

Boletin de estudios medicos y biologicos Pub Date : 1993-01-01

A González-Quevedo, J C García, R Fernández, L Fernández Cartaya

{"title":"Monoamine metabolites in normal human cerebrospinal fluid and in degenerative diseases of the central nervous system.","authors":"A González-Quevedo, J C García, R Fernández, L Fernández Cartaya","doi":"","DOIUrl":"","url":null,"abstract":"Measurement of monoamine metabolites in cerebrospinal fluid (CSF) has been one of the few methods available to study monoamine transmitter function in the human central nervous system (CNS). It has steadily proved to be of much use in clinical research of neurological and psychiatric diseases, in which altered functions of central monoamine neurotransmitters have been identified. In this work 3-methoxy-4-hydroxyphenylethylglycol (MHPG), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were quantified in normal CSF and in patients with untreated Parkinson's disease (PD) and olivopontocerebellar atrophy (OPCA). Normal CSF was obtained from 162 patients at the time of spinal anesthesia for surgery. Reference values for monoamine metabolites were established for normal adult lumbar CSF. Up to the age of 70 years no relation of monoamine metabolite concentration with age or sex were encountered. In individuals above 70 years of age higher levels of MHPG, HVA, and 5-HIAA were present in women, while in men only higher levels of MHPG could be detected. A strong correlation between 5-HIAA and HVA concentrations were observed in all groups. PD patients exhibited normal CSF metabolite levels, but an altered 5-HIAA/HVA ratio, favoring 5-HIAA. Dominant and recessive OPCA differed essentially in HVA concentration-diminished in the first group and elevated in the last. Comparing the results obtained in PD and dominant OPCA, we suggest that the decrease of CSF HVA in the latter group might not reflect nigrostriatal degeneration as we previously thought. Possibly another factor influencing dopamine function in the CNS is involved.","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"41 1-4","pages":"13-9"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18528116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of levonorgestrel action on the flank organ and the sebaceous gland lipogenesis of female hamsters. 左炔诺孕酮对雌性仓鼠侧腹器官和皮脂腺脂肪生成作用的评价。

Boletin de estudios medicos y biologicos Pub Date : 1993-01-01

M Cabeza, L Díaz de León

{"title":"Evaluation of levonorgestrel action on the flank organ and the sebaceous gland lipogenesis of female hamsters.","authors":"M Cabeza, L Díaz de León","doi":"","DOIUrl":"","url":null,"abstract":"The role of testosterone and levonorgestrel action on the flank organ by measuring sebaceous gland lipogenesis of female hamsters by the metabolic incorporation of 14C-glucose were investigated. Also, a partial characterization of the radiolabeled lipid fraction was obtained. The effects of in vivo steroids administration were evaluated by 14C-U-glucose metabolic incorporation into lipids by the female hamster flank organs in culture conditions, in the presence or absence of LNG and/or T in the incubation medium. The radioactive lipids were identified by thin layer chromatography. Levonorgestrel alone or together with testosterone on female hamster flank organs decreased the organ weight and sebum content compared with T-treatment alone. In culture conditions, a rapid and significant increase of radiolabeled glucose was observed with T. By contrast when LNG was present in the incubation medium, no differences in 14C-U-glucose incorporation were observed when compared with their controls. When T+LNG were added, a similar result to the obtained when using LNG alone was determined. Testosterone increased glycerides and free fatty acids but decreased polar lipids; whereas LNG did not have any effect in the relative proportions of 14C-U-glucose incorporated into the different classes of lipids, when it was compared with their controls. The results indicated that LNG abolished the increasing effect of 14C glucose incorporation caused by T and changed the lipid composition induced on female hamsters flank organs.","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"41 1-4","pages":"20-7"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19068427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective effect of nickel chloride on superoxide damage: enhancement of CuZn superoxide dismutase affinity to the oxygen free radical. 氯化镍对超氧化物损伤的保护作用:增强CuZn超氧化物歧化酶对氧自由基的亲和力。

Boletin de estudios medicos y biologicos Pub Date : 1993-01-01

E L Novelli, N L Rodrigues, B O Ribas

引用次数: 0

Effects of nimodipine on multiunit activity of several brain structures following acute global cerebral ischemia-anoxia in cats. 尼莫地平对猫急性全脑缺血-缺氧后几种脑结构多单位活动的影响。

Boletin de estudios medicos y biologicos Pub Date : 1992-01-01

M Cervantes, I Chávez-Carrillo, A Antonio-Ocampo

{"title":"Effects of nimodipine on multiunit activity of several brain structures following acute global cerebral ischemia-anoxia in cats.","authors":"M Cervantes, I Chávez-Carrillo, A Antonio-Ocampo","doi":"","DOIUrl":"","url":null,"abstract":"The effects of nimodipine, a 1,4-dihydropyridine calcium channel blocker, on multiunit activity (MUA) of several brain structures were investigated in cats during 6 h immediately following acute global cerebral ischemia-anoxia induced by a 10 min cardiorespiratory arrest (CRA), as well as in cats exposed to sham procedures corresponding to CRA. Four groups of cats were studied: 1) CRA and continuous administration of nimodipine, 1 microgram/kg/min iv during 6 h; 2) CRA and continuous administration of vehicle; 3) sham and continuous administration of nimodipine as in group 1; 4) sham and vehicle as in group 2. MUA and electroencephalogram disappeared during ischemia-anoxia; their progressive recovery occurred throughout the hours following CRA, although 6 h after CRA MUA was still lower than its control prearrest values in all the recorded subcortical structures. Delta-like waves, isolated spikes, and bursts of fast EEG waves occurred during the recovery of EEG activity. Nimodipine inhibited the otherwise increasing MUA in mesencephalic reticular formation, hippocampus and putamen, but not in ventromedial hypothalamus, during the hours following acute global cerebral ischemia-anoxia. Absence of isolated spikes and bursts of fast EEG activity was noted in the EEG of CRA-, nimodipine-treated cats. Nimodipine significantly reduced MUA in hippocampus but not in other cerebral structures in cats of the sham treated group. The results suggest the involvement of 1,4 dihydropyridine sensitive calcium channels in the cellular mechanisms related to neuronal activity after cerebral ischemia-anoxia, and the possible relationship between the effects of nimodipine on MUA and better functional conditions of the central nervous system after acute global cerebral ischemia-anoxia.","PeriodicalId":75608,"journal":{"name":"Boletin de estudios medicos y biologicos","volume":"40 1-4","pages":"21-30"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12471252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0