Biomembranes最新文献_第3页

Notes on the heterogeneity, circulation, and modification of membranes, with emphasis on secretory cells, photoreceptors, and the toad bladder. 注意细胞膜的异质性、循环和修饰，重点是分泌细胞、光感受器和蟾蜍膀胱。

Biomembranes Pub Date : 1979-01-01 DOI: 10.1007/978-1-4615-6564-2_3

E Holtzman, G Gronowicz, A Mercurio

引用次数: 11

Lipoprotein of the outer membrane of Escherichia coli. 大肠杆菌外膜脂蛋白。

Biomembranes Pub Date : 1979-01-01 DOI: 10.1007/978-1-4615-6564-2_4

M Inouye

引用次数: 26

Membrane transport an interdisciplinary approach. 膜运输是一个跨学科的方法。

Biomembranes Pub Date : 1977-01-01

A Kotyk, K Janácek

引用次数: 0

Organization of glycoprotein and glycolipid in the plasma membrane of normal and transformed cells as revealed by galactose oxidase. 半乳糖氧化酶显示正常细胞和转化细胞质膜中糖蛋白和糖脂的组织。

Biomembranes Pub Date : 1976-01-01 DOI: 10.1007/978-1-4684-9087-9_4

C G Gahmberg, S Hakomori

引用次数: 19

Cell membrane associated antigens in chemical carcinogenesis. 化学癌变中的细胞膜相关抗原。

Biomembranes Pub Date : 1976-01-01 DOI: 10.1007/978-1-4684-9087-9_3

R W Baldwin, M R Price

引用次数: 2

Intracellular localization and immunogenic capacities of phenotypic products of mouse histocompatibility genes. 小鼠组织相容性基因表型产物的细胞内定位和免疫原性。

Biomembranes Pub Date : 1976-01-01 DOI: 10.1007/978-1-4684-9087-9_2

L A Manson

{"title":"Intracellular localization and immunogenic capacities of phenotypic products of mouse histocompatibility genes.","authors":"L A Manson","doi":"10.1007/978-1-4684-9087-9_2","DOIUrl":"https://doi.org/10.1007/978-1-4684-9087-9_2","url":null,"abstract":"The transplantation antigens are the phenotypic products of genes which control histocompatibility in vertebrate species. The products of major histocompatibility locus of the mouse, H-2, have been studied as a model. The H-2 transplantation antigens are expressed on cellular membranes in all tissues examined. These gene products have been isolated from cells associated with subcellular membranes. These membranes have been assayed both for their antigen content (antigenicity) and for their capacities to induce a primary humoral and a cell-mediated response (immunogenicity). In all tissues examined, the H-2 antigens (products of the K and D regions of H-2) were found expressed in high concentration on cell surface membrane. However, immunogenic activity was observed only with spleen and thymus preparations, consisting mainly of intracellular membranes (MLP). Immunogenic MLP was also isolated from lymphoblast and fibroblast cells, and again was derived mainly from endoplasmic reticulum. In other tissues, such as liver, kidney, and erythrocytes, H-2 antigens were found only on surface membrane and in an antigenic but nonimmunogenic form. A novel method for tagging surface membrane of mammalian cells is presented. It consists of binding, to whole cells in a covalent linkage, purified preparations of the beta-galactosidase of E. coli. The bound enzyme has proved to be an unambiguous marker for surface membrane. With this marker, the stability of surface membrane to shear forces during homogenization could be assessed. A number of considerations suggest that immunogenicity of transplantation antigens may be due to factor(s) present on the membranes in addition to the H-2 antigenic determinants. There are indications that these factors may be controlled by the I region of the H-2 complex. It is interesting to note that normal tissues which have Ia antigens on their surface membranes yield immunogenic MLP (spleen and thymus), whereas those without Ia surface antigens yield an antigenic MLP that has no immunogenic capacity (liver, kidney, and erythrocytes).","PeriodicalId":75600,"journal":{"name":"Biomembranes","volume":"8 ","pages":"47-88"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11977466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Surface alterations in cells infected by avian leukosis-sarcoma viruses. 禽白血病-肉瘤病毒感染细胞的表面改变。

Biomembranes Pub Date : 1976-01-01 DOI: 10.1007/978-1-4684-9087-9_5

R Kurth

引用次数: 11

Distribution of transplantation antigens on cell surfaces. 移植抗原在细胞表面的分布。

Biomembranes Pub Date : 1976-01-01 DOI: 10.1007/978-1-4684-9087-9_1

W C Davis, H E Sandberg, P H DeFoor

{"title":"Distribution of transplantation antigens on cell surfaces.","authors":"W C Davis, H E Sandberg, P H DeFoor","doi":"10.1007/978-1-4684-9087-9_1","DOIUrl":"https://doi.org/10.1007/978-1-4684-9087-9_1","url":null,"abstract":"Significant advances have been made over the past few years in elucidating the genetics, the chemical composition, and, more recently, the in situ relation of the major histocompatibility antigens of the mouse and man. Attempts to map the arrangement of individual antigens on the surface of cells have revealed that some antigens specified by a given subregion of both the H-2 and HL-A systems are in close proximity on the cell membrane and that attachment of antibody to one site to a certain degree blocks or inhibits the binding of antibody to the adjacent site. Allelic antigens in the H-2 system tend to inhibit binding. H-2D and H-2K antigens show either inhibition or noninteraction, possibly reflecting a cis-trans effect. Unlike with the H-2, inhibition of binding occurs only between HL-A antigens specified by homologous chromosomes. Also, a number of instances have been noted where inhibition of binding is unidirectional, possibly reflecting a polymeric nature of antigen or stratification of moieties at cell surface. Inhibition of antibody attachment between several alloantigenic systems on thymocytes in mice and also a variation in the mobility of the histocompatibility antigens suggest that the moieties bearing histocompatibility antigens are comprised of several gene products. Further work is needed to establish the validity of this assumption and to fully define the composition of these units. Ample data have been obtained from both biological and biophysical experiments to support the suggestion that single or multiple complexes of glycoproteins can move in the plane of the membrane. Although the composition of these cell membrane components remains a question, direct visualization by fluorescence and electron microscopy indicates that these moieties are small and, under natural conditions, distributed uniformly over the cell surface. Direct and indirect labeling techniques have shown that the complexes have no fixed position in the cell membrane and can be displaced laterally in the plane of the membrane without affecting the distribution of other surface molecules, such as sIg and species-specific antigens. Additional evidence suggests that H-2D and H-2K antigen complexes, as well as their gene products specified by different parent chromosomes, may be displaced separately. These observations are especially interesting and must be reconciled and data obtained by proximity analysis which indicate an association of some allelic products and possibly certain combinations of D and K antigens. Whether the differences noted in reactivity of the various surface antigens following attachment of antibodies are attributable to difference in size or to differences in the manner of their intercalation in the cell membrane remains to be elucidated. The rapid advances in elucidation of the molecular structure of biological membranes suggest that experimental work should be done on the biophysics of the structure of the antigenic sites and the me","PeriodicalId":75600,"journal":{"name":"Biomembranes","volume":"8 ","pages":"1-46"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11977464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Bacterial Membranes and the Respiratory Chain 细菌膜和呼吸链

Biomembranes Pub Date : 1975-08-01 DOI: 10.1007/978-1-4684-7709-2

N. S. Gel’man, M. Lukoyanova, D. Ostrovskii

引用次数: 24

Factors influencing the retention of K in a Halobacterium. 影响盐杆菌中钾潴留的因素。

Biomembranes Pub Date : 1975-01-01 DOI: 10.1007/978-1-4684-7668-2_8

M Ginzburg, B Z Ginzburg

引用次数: 12