Bibliotheca cardiologica最新文献

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Cyto-immunologic monitoring following heart transplantation. 心脏移植后的细胞免疫监测。
Bibliotheca cardiologica Pub Date : 1988-01-01
P L Wijngaard, A Heyn, A van der Meulen, H de Vries
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引用次数: 0
Aprotinin decreases the need for post-operative blood transfusions in patients having open heart surgery. 抑酶蛋白降低了心内直视手术患者术后输血的需要。
Bibliotheca cardiologica Pub Date : 1988-01-01
D Royston, B D Bidstrup, K M Taylor, R N Sapsford
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引用次数: 0
New trends in heart transplantation. 1st Vienna symposium. Vienna, September 18-19, 1987. Proceedings. 心脏移植的新趋势。第一届维也纳专题讨论会。维也纳,1987年9月18日至19日。程序。
Bibliotheca cardiologica Pub Date : 1988-01-01
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引用次数: 0
Monitoring of cardiac transplants with beta 2-microglobulin, cytoimmunological monitoring and endmyocardial biopsy: what's their value in detecting rejection? 2-微球蛋白监测、细胞免疫监测和心肌终末活检对心脏移植排斥反应的监测价值?
Bibliotheca cardiologica Pub Date : 1988-01-01
M Semik, W Konertz, E Westphal, U Heusermann, A Friedl, A Bernhard
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引用次数: 0
Cytokines in the regulation of allograft rejection. 细胞因子对同种异体移植排斥反应的调控。
Bibliotheca cardiologica Pub Date : 1988-01-01
C Huber, E Irschick
{"title":"Cytokines in the regulation of allograft rejection.","authors":"C Huber,&nbsp;E Irschick","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Stimulation of T lymphocytes with alloantigen leads to release of both IL-2 and IFN-gamma. IL-2 enhances clonal expansion of alloantigen-activated T cells. This permits it to overcome acquired allograft tolerance which, at the efferent limb of the cellular immune response, is caused by reduced clone size of donor-specific cytotoxic lymphocyte precursor cells. Cells exhibiting a low constitutive expression of class I MHC antigenes are refractory to lysis by cytotoxic T cells. This second type of tolerance located at the level of the allogeneic target cells can be easily broken by exogenous IFN-gamma, which increases the density of class I MHC antigens. There is suggestive evidence for enhanced endogenous production of lymphokines during rejection of cardiac allografts in mice and men. Rejection episodes are also associated with increased expression of class I and elevated frequency of class II MHC antigen-positive cells in the cardiac transplants. Whereas early immune recognition of histoincompatible grafts is primarily related to the presence of genetic barriers between donor and recipient, the further amplification of alloreactivity is driven by the release of antigen-unspecific lymphokines. Production of endogenous lymphokines can be modified by a variety of means: methylprednisone, ciclosporin and specific antibodies against lymphokines or their receptors represent effective inhibitors of this amplification mechanism which can finally lead to irreversible graft damage. It is well established in clinical experience that infectious complications subsequent to allografting may precipitate rejection or graft-vs.-host disease. Our finding of increased endogenous IFN-gamma levels during infections, in particular in those caused by cytomegalovirus, provides an explanation for this association.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":75589,"journal":{"name":"Bibliotheca cardiologica","volume":" 43","pages":"103-10"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14277876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experience with early quadruple immunosuppressive therapy in heart transplantation. 心脏移植早期四联免疫抑制治疗的体会。
Bibliotheca cardiologica Pub Date : 1988-01-01
M Goenen, J Col, P Baele, D Latinne, H Noel, G Alexandre, J C Schoevardts, R Ponlot, C Chalant
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引用次数: 0
Measurement and disposition of ciclosporin and its metabolites. 环孢素及其代谢产物的测定和处理。
Bibliotheca cardiologica Pub Date : 1988-01-01
K F Sewing, U Christians, J S Bleck, R Schottmann, S S Strohmeyer
{"title":"Measurement and disposition of ciclosporin and its metabolites.","authors":"K F Sewing,&nbsp;U Christians,&nbsp;J S Bleck,&nbsp;R Schottmann,&nbsp;S S Strohmeyer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75589,"journal":{"name":"Bibliotheca cardiologica","volume":" 43","pages":"63-72"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14199100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The diagnosis of acute cardiac rejection by endomyocardial biopsy. 急性心脏排斥反应的心肌内膜活检诊断。
Bibliotheca cardiologica Pub Date : 1988-01-01
M E Billingham
{"title":"The diagnosis of acute cardiac rejection by endomyocardial biopsy.","authors":"M E Billingham","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75589,"journal":{"name":"Bibliotheca cardiologica","volume":" 43","pages":"83-102"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14199101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunosuppression in cardiac transplantation. 心脏移植中的免疫抑制。
Bibliotheca cardiologica Pub Date : 1988-01-01
E A Rose, L J Addonizio
{"title":"Immunosuppression in cardiac transplantation.","authors":"E A Rose,&nbsp;L J Addonizio","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75589,"journal":{"name":"Bibliotheca cardiologica","volume":" 43","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14199082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent developments in ciclosporin measurements. 环孢素测量的最新进展。
Bibliotheca cardiologica Pub Date : 1988-01-01
A Johnston, J T Marsden, D W Holt
{"title":"Recent developments in ciclosporin measurements.","authors":"A Johnston,&nbsp;J T Marsden,&nbsp;D W Holt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75589,"journal":{"name":"Bibliotheca cardiologica","volume":" 43","pages":"60-2"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14358906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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