Bibliotheca anatomica最新文献_第7页

Evolution of the stroma in human chorionic villi throughout pregnancy. 妊娠期间人绒毛膜绒毛基质的演变。

Bibliotheca anatomica Pub Date : 1982-01-01

M Castellucci, P Kaufmann

引用次数: 0

Placentone structure of the human placenta. 人类胎盘的胎盘素结构。

Bibliotheca anatomica Pub Date : 1982-01-01

R A Schuhmann

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Specificity of neural connections in the retinotectal system. 视网膜顶系统中神经连接的特异性。

Bibliotheca anatomica Pub Date : 1982-01-01

G Rager

{"title":"Specificity of neural connections in the retinotectal system.","authors":"G Rager","doi":"","DOIUrl":"","url":null,"abstract":"The existence of a retinotopic map raises the question of how such a map is formed during development. Since little is known about molecular mechanisms which may be involved in the formation of retinotopy, the structural aspects of this developmental process were studied to a greater detail in the chick. In the retina the following patterns of growth can be observed: (1) Ganglion cell formation starts in the centre and spreads towards the periphery. Thus, each cell is labelled by both its position and its time of origin. (2) Axons tend to grow towards the optic fissure by the shortest possible route, and more peripheral axons whose perikarya are born later than that of central ones tend to lie next to the inner limiting membrane. A regular change in the pattern of fibres, which we call transformation, occurs at the optic fissure. The incremental rings are transformed into crescents lying ventrally in the optic stalk at early stages of development. In the middle of the optic nerve retinotopy is re-established. Another transformation occurs shortly behind the chiasm. Except for these transformations, fibres run parallel to each other even across the chiasm. Thus, fibres arriving at the optic tectum are well organized. It is concluded that a multiplicity of factors contribute to the formation of the retinotectal map at any site of the visual pathway. The analysis of these factors may indicate how topographically organized projections develop.","PeriodicalId":75588,"journal":{"name":"Bibliotheca anatomica","volume":" 23","pages":"95-102"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18152553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response of central monoamine neurons following an early neurotoxic lesion. 早期神经毒性损伤后中枢单胺神经元的反应。

Bibliotheca anatomica Pub Date : 1982-01-01

G Jonsson, H Hallman

{"title":"Response of central monoamine neurons following an early neurotoxic lesion.","authors":"G Jonsson, H Hallman","doi":"","DOIUrl":"","url":null,"abstract":"Systemic treatment with the selective monoamine neurotoxins 6-hydroxydopamine (6-OH-DA), N-(2-chloroethyl)N-ethyl-2-bromobenzylamine (DSP4) or 5,7-dihydroxytryptamine (5,7-HT) in the neonatal stage produces marked and permanent alterations of the postnatal development of central noradrenaline (NA) and 5-hydroxytryptamine (5-HT) neurons. 6-OH-DA and DSP4 act preferentially on NA neurons, in particular on the locus coeruleus system, whereas 5,7-HT acts on 5-HT neurons. The neurotoxin treatment leads to pronounced denervations of distant nerve terminal projections while innervation areas close to the cell bodies become hyperinnervated. The total number of monoamine nerve terminals developed in the CNS after the neurotoxin treatment is approximately unchanged. A surgical lesion of NA and 5-HT axons in the neonatal stage causes similar changes compared to a neonatal neurotoxin treatment. The postsynaptic monoamine receptors appear to develop independently of the presynaptic nerve terminals, although the transmitter availability at the receptors is able to regulate the number of receptors (up and down regulation). The transmitter turnover is increased in terminals spared by the neurotoxin in denervated areas, while decreased in hyperinnervated regions. The alterations in receptor density and transmitter turnover may represent compensatory mechanisms. Substance P has a counteracting effect while morphine has a potentiating effect on the 6-OH-DA-induced NA denervation and hyperinnervation, indicating that the functional state of the neuron may modulate the final outcome of a neonatal 6-OH-DA treatment. The results indicate that the altered development of central monoamine neurons following a neonatal monoamine neurotoxin treatment or axotomy is mainly related to a 'pruning effect', i.e. the prevention of the development of one axonal branch leads to a proliferative growth response in intact branches.","PeriodicalId":75588,"journal":{"name":"Bibliotheca anatomica","volume":" 23","pages":"76-92"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17352773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Locus coeruleus - cerebellum: interaction during development. 蓝斑-小脑:发育过程中的相互作用。

Bibliotheca anatomica Pub Date : 1982-01-01

J Sievers, H P Klemm

{"title":"Locus coeruleus - cerebellum: interaction during development.","authors":"J Sievers, H P Klemm","doi":"","DOIUrl":"","url":null,"abstract":"The presentation describes a combined morphological and biochemical analysis of the developmental interaction between the locus coeruleus (LC) and the cerebellum of rats, which receives an afferent innervation from the LC. The LC neurons are among the first CNS neurons to arise during ontogeny. They establish axonal connections to their target areas while migrating into their nuclear area, where they collect around E17. Their perikaryal development proceeds through the well-known stages of neuronal differentiation, Nissl body formation as a sign of synaptic connectivity appearing for the first time on E18. However, changes in the LC-perikarya are taking place in early postnatal stages. Perikaryal volume increases to reach a transitory maximum of 150% of the adult value on P15. Ultrastructurally, a dissolution of Nissl bodies and an increase in the number of polyribosomes are seen during this developmental period, reminiscent of perikaryal changes during the axon reaction. Later, the organization of ribonucleoproteins into Nissl bodies is re-established. NA axons are demonstrable in the cerebellar anlage for the first time on E17. They increase rapidly in number and organization during cerebellar development as shown by catecholamines histofluorescence. Quantitative measurements of cerebellar high-affinity uptake for NA show that a peak of NA innervation is reached on P10, which amounts to about 250% of the adult value. This hyper-innervation is transitory and declines to adult values on P20. The period of cerebellar NA hyperinnervation corresponds to the perikaryal changes in volume and ultrastructure of LC neurons. The phenomenon of transitory hyperinnervation of a target area is discussed with respect to the establishment of axonal connections during normal development and in regeneration.","PeriodicalId":75588,"journal":{"name":"Bibliotheca anatomica","volume":" 23","pages":"56-75"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17353614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Growth and regeneration of axons in the nervous system. 神经系统轴突的生长和再生。

Bibliotheca anatomica Pub Date : 1982-01-01

引用次数: 0

Immunohistochemical demonstration of human and murine pregnancy-associated serum proteins in maternal and placental tissue. 母体和胎盘组织中人类和小鼠妊娠相关血清蛋白的免疫组织化学证明。

Bibliotheca anatomica Pub Date : 1982-01-01

J Chemnitz, J Hau, P Svendsen, J Folkersen, J G Westergaard, B C Christensen

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Nicotinic ACh receptor blockade and spontaneous nerve cell death in various brain regions. 烟碱乙酰胆碱受体阻断与脑各区域自发性神经细胞死亡。

Bibliotheca anatomica Pub Date : 1982-01-01

K Zilles, C M Becker, A Schleicher

引用次数: 0