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Acta radiologica: oncology, radiation, physics, biology最新文献

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Treatment of carcinoma of base of tongue with radiation therapy and 5-fluorouracil. Potential for optimization with 18F-FU. 放射治疗联合5-氟尿嘧啶治疗舌底癌。18F-FU的优化潜力。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128211
A L Wiley, G Ramirez, R O Johnson, J H Brandenburg, L M Lieberman, T C Lo, H Vermund
{"title":"Treatment of carcinoma of base of tongue with radiation therapy and 5-fluorouracil. Potential for optimization with 18F-FU.","authors":"A L Wiley,&nbsp;G Ramirez,&nbsp;R O Johnson,&nbsp;J H Brandenburg,&nbsp;L M Lieberman,&nbsp;T C Lo,&nbsp;H Vermund","doi":"10.3109/02841867909128211","DOIUrl":"https://doi.org/10.3109/02841867909128211","url":null,"abstract":"<p><p>The treatment of advanced base of tongue carcinoma with concurrent radiation therapy and 5-fluorouracil versus radiation therapy alone is compared. Although the results are inconclusive, it is noteworthy that all the 5-year survivors were patients given combined treatment. Important questions regarding optimization of time-dose relationships with combined therapy were generated. Accordingly, 18F-5 fluorouracil was synthesized in an attempt to answer some of these questions.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 3","pages":"235-43"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11337861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Basal cell carcinoma treated with MTDQ and irradiation. MTDQ联合放射治疗基底细胞癌。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128195
Z Pollák, J Fodor, V Erdélyi, O Bihari, S Eckhardt
{"title":"Basal cell carcinoma treated with MTDQ and irradiation.","authors":"Z Pollák,&nbsp;J Fodor,&nbsp;V Erdélyi,&nbsp;O Bihari,&nbsp;S Eckhardt","doi":"10.3109/02841867909128195","DOIUrl":"https://doi.org/10.3109/02841867909128195","url":null,"abstract":"<p><p>Patients with basal cell carcinoma of the skin were treated with combined MTDQ (6,6'-methylene-bis-(2,2,4-trimethyl-1,2-dihydroquinoline)) administration and irradiation. Significantly better results were obtained with a skin exposure of 2 000 R combined with MTDQ than with the same dose alone. The results were comparable to those obtained with an exposure of 4 000 R. MTDQ administration induced decrease of tissular malonaldehyde concentration and suggested the peroxide-decomposing action of the radiation sensitizer.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 2","pages":"97-102"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128195","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11700164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Radiation sensitivity change of hemopoietic cells induced by hydroxyurea. 羟基脲诱导造血细胞辐射敏感性的变化。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128200
Y Maruyama, C Magura, J Feola
{"title":"Radiation sensitivity change of hemopoietic cells induced by hydroxyurea.","authors":"Y Maruyama,&nbsp;C Magura,&nbsp;J Feola","doi":"10.3109/02841867909128200","DOIUrl":"https://doi.org/10.3109/02841867909128200","url":null,"abstract":"<p><p>Hemopoietic tissues of mice contain cells capable of proliferation and differentiation to form endogenous spleen colonies (Endo-CFU-S) in irradiated animals. Hydroxyurea (HU) given before irradiation of C57BL mice for endogenous CFU assay increased the number of surviving CFU-S twofold. Either HU or HSATT given after the initial stimulus abolished this rise. In vivo and in vitro 'suicide' assays of spleen cells indicated that cells were stimulated by the HU or the initial stimulus to enter into DNA synthesis shortly after stimulation. The resting CFU cell population appeared to be positioned close to DNA-S phase and responded to the stimulus by entry into S phase. Whole body irradiation at intervals after HU revealed a changing radiation sensitivity of the endogenous CFU-S consistent with drug-induced progression with decreased radiation sensitivity of the S phase cohort of cells.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 2","pages":"136-44"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128200","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11262926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Vascular structure of experimental tumours. Appearances in scanning electron microscope. 实验性肿瘤的血管结构。扫描电镜外观。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128223
J Egawa, K Ishioka, T Ogata
{"title":"Vascular structure of experimental tumours. Appearances in scanning electron microscope.","authors":"J Egawa,&nbsp;K Ishioka,&nbsp;T Ogata","doi":"10.3109/02841867909128223","DOIUrl":"https://doi.org/10.3109/02841867909128223","url":null,"abstract":"<p><p>The vascular structure of experimental tumours was investigated by a resin cast technique. Six characteristic types of capillaries were found: club-like, wave-like, tortuous,sinusoid-like, disorderly running and tapering. The vascular structure was correlated to the tumour growth.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 4","pages":"367-75"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128223","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Nephroblastoma. Results and complications of treatment. 肾胚细胞瘤。治疗结果及并发症。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128230
H Schultz, B Jacobsen, K B Jensen, A Sell
{"title":"Nephroblastoma. Results and complications of treatment.","authors":"H Schultz,&nbsp;B Jacobsen,&nbsp;K B Jensen,&nbsp;A Sell","doi":"10.3109/02841867909128230","DOIUrl":"https://doi.org/10.3109/02841867909128230","url":null,"abstract":"<p><p>Treatment results in 31 patients with nephroblastoma are reported. Survival seemed superior in patients who received Actinomycin-D in addition to surgery and postoperative irradiation. Twelve long-term surviving children were evaluated for side-effects of the treatment. Although inhibition of growth and other abnormalities occurred in most survivors, little permanent disability and dysfunction appears to have resulted from the treatment.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 5","pages":"449-59"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128230","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11445798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Early effects in kidney enzyme activities after irradiation. 辐照后肾酶活性的早期影响。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128208
F Franciolini, A Becciolini, A Rossi, V Giaché, M Balzi, A Nardino
{"title":"Early effects in kidney enzyme activities after irradiation.","authors":"F Franciolini,&nbsp;A Becciolini,&nbsp;A Rossi,&nbsp;V Giaché,&nbsp;M Balzi,&nbsp;A Nardino","doi":"10.3109/02841867909128208","DOIUrl":"https://doi.org/10.3109/02841867909128208","url":null,"abstract":"<p><p>Brush border enzymes of proximal tubules, lysosomal activities and protein content of rat kidney were analysed after whole-body irradiation using two different experimental schedules. Maltase, alkaline phosphatase and beta-glucuronidase activities increased moderately during the first days after irradiation, whereas LAP, cathespsin D activities and protein content were not modified. No evident morphologic alterations were observed.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 3","pages":"209-17"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128208","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11600391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Tamoxifen treatment of advanced breast carcinoma. 他莫昔芬治疗晚期乳腺癌。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128207
K Roesdahl
{"title":"Tamoxifen treatment of advanced breast carcinoma.","authors":"K Roesdahl","doi":"10.3109/02841867909128207","DOIUrl":"https://doi.org/10.3109/02841867909128207","url":null,"abstract":"<p><p>Sixty postmenopausal patients with microscopically confirmed, progressive mammary carcinoma and local recurrence alone or in combination with distant metastases or with distant metastases only, not previously treated with cytostatics, were given tamoxifen (Nolvadex), 10 mg 3 times daily. The response rate in 37 evaluable patients was 48 per cent, with a median duration of the response of 26+ weeks. The effectiveness of the drug increased significantly with an increasing interval between primary treatment and the appearance of the first recurrence. No serious side effects occurred.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 3","pages":"203-8"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11312942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of irradiation on the feto-placental tissues. 辐照对胎胎盘组织的影响。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128199
T Iversen, K Talle, F Langmark
{"title":"Effect of irradiation on the feto-placental tissues.","authors":"T Iversen,&nbsp;K Talle,&nbsp;F Langmark","doi":"10.3109/02841867909128199","DOIUrl":"https://doi.org/10.3109/02841867909128199","url":null,"abstract":"<p><p>Seven pregnant patients with genital carcinoma were treated with high voltage irradiation in combination with operation. Five patients aborted spontaneously after a dose of 30 to 34 Gy. Two were operated within 2 weeks after completed irradiation. Angiography, microscopy and hormone analyses indicate that damage of the fetal central nervous system and not placental insufficiency is responsible for the intrauterine fetal death.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 2","pages":"129-35"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128199","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11335314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Combination chemotherapy in advanced postmenopausal mammary carcinoma. A comparison between VAC and VACM therapy. 晚期绝经后乳腺癌的联合化疗。VAC与VACM治疗的比较。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128228
W Mattsson, A Arwidi, F von Eyben, C E Lindholm
{"title":"Combination chemotherapy in advanced postmenopausal mammary carcinoma. A comparison between VAC and VACM therapy.","authors":"W Mattsson,&nbsp;A Arwidi,&nbsp;F von Eyben,&nbsp;C E Lindholm","doi":"10.3109/02841867909128228","DOIUrl":"https://doi.org/10.3109/02841867909128228","url":null,"abstract":"<p><p>A randomized trial comparing Vincristine, Adriamycin, Cyclophosphamide (VAC) with or without Methotrexate with citrovorum factor rescue (VACM) was performed in 64 patients with metastatic postmenopausal mammary carcinoma. Previous treatment of metastases, dominant site of metastases and performance condition were similar in the patients. No significant difference was found in the response rates (complete remission + partial remission; VAC 21/31, VACM 25/33), in the duration of the remissions or in the survivals. The duration of remission in CR was significantly longer than in PR. No serious side effects were observed. The VAC regimen is preferable, particularly with respect to the costs and the simple procedure of administration.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 5","pages":"431-44"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128228","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11600527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Clinico-pathologic correlation in non-Hodgkin's lymphoma. I. Retrospective analysis using the Lukes and Collins classification. 非霍奇金淋巴瘤的临床病理相关性。1 .采用Lukes和Collins分类进行回顾性分析。
Acta radiologica: oncology, radiation, physics, biology Pub Date : 1979-01-01 DOI: 10.3109/02841867909128205
P Lenner, E Lundgren, L Damber
{"title":"Clinico-pathologic correlation in non-Hodgkin's lymphoma. I. Retrospective analysis using the Lukes and Collins classification.","authors":"P Lenner,&nbsp;E Lundgren,&nbsp;L Damber","doi":"10.3109/02841867909128205","DOIUrl":"https://doi.org/10.3109/02841867909128205","url":null,"abstract":"<p><p>A retrospective review of 302 patients with non-Hodgkin's lymphoma is presented. The tumors were classified according to a modified Lukes and Collins scheme. Clinico-pathologic correlation was analysed for the subtypes. Certain distinct features were found with respect to age, sex, clinical stage and sites of involvement at admission. Prognostically, two major groups were found with significantly differing survival curves. The pathologic and clinical significance of the modified Lukes and Collins classification is discussed.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 3","pages":"177-91"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128205","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11729167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
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