Acta cientifica venezolana最新文献

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Priming rapacuronium: a comparison with rocuronium and mivacurium. 起动雷帕库溴铵:与罗库溴铵和真空的比较。
Acta cientifica venezolana Pub Date : 2003-01-01
David Steinberg
{"title":"Priming rapacuronium: a comparison with rocuronium and mivacurium.","authors":"David Steinberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this study is to present the pharmacodynamics of the priming principle using rapacuronium and a comparison with rocuronium and mivacurium. After induction, 120 patients were randomly allocated to six similar groups. Groups 1 and 2 received rapacuronium 1000 micrograms.Kg-1 as a bolus or primed with 100 micrograms.Kg-1. To groups 3 and 4, rocuronium 400 micrograms.Kg-1 were given as a bolus or primed with 60 micrograms.Kg-1, finally mivacurium 100 micrograms.Kg-1 was used for groups 5 and 6 by bolus or primed with 10 micrograms.Kg-1. Neuromuscular function was monitored by electromyography and it was demonstrated that time to 80% blockade, is significantly shorter after priming: 137 (bolus) vs 101 seconds (priming) for rapacuronium, 160 vs 90 for rocuronium and 196 vs 118 for mivacurium. Onset time was also statistically accelerated by priming: 229 seconds vs 183, 289 vs 203 and 298 vs 252 respectively. No significant change was noticed in maximal blockade and clinical duration due to priming. During early onset, only the mivacurium patients showed a statistical difference in train of four fade between bolus and priming. In conclusion, priming hasten early and maximal effect produced by rapacuronium, rocuronium and mivacurium without any change in maximal blockade and clinical duration. Pre-synaptic effect does not explain consistently the mode of action of priming.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 2","pages":"115-20"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24405525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the modelling bone tissue fracture and healing of the bone tissue. 骨组织的建模、骨折及骨组织的愈合。
Acta cientifica venezolana Pub Date : 2003-01-01
Manuel Doblaré, José Manuel García
{"title":"On the modelling bone tissue fracture and healing of the bone tissue.","authors":"Manuel Doblaré,&nbsp;José Manuel García","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper reviews the available literature on computational modelling in two areas of bone biomechanics: fracture and healing. Bone fracture analysis attempts to predict the failure of musculoskeletal structures by several possible mechanisms under different loading conditions. However, as opposed to structurally inert materials, bone is a living tissue that can repair itself. An exciting new field of research is being developed to better comprehended these mechanisms and the mechanical behaviour of bone tissue. One of the main goals of this work is to demonstrate, after a review of computational models, the main similarities and differences between normal engineering materials and bone tissue from a structural point of view. We also underline the importance of computational simulations in biomechanics due to the difficulty of obtaining experimental or clinical results.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 1","pages":"58-75"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40907730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[On bitumen emulsions in water]. [沥青乳剂在水中]。
Acta cientifica venezolana Pub Date : 2003-01-01
Hercilio Rivas, Xiomara Gutierrez, Felix Silva, Manuel Chirinos
{"title":"[On bitumen emulsions in water].","authors":"Hercilio Rivas,&nbsp;Xiomara Gutierrez,&nbsp;Felix Silva,&nbsp;Manuel Chirinos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The most important factors, controlling the process of emulsification of highly viscous hydrocarbons in water, which are responsible for keeping the stability and other properties of these systems, are discused in this article. The effect of non-ionic surfactants, such as nonil phenol ethoxilated compounds on the interfacial behavior of bitumen/water systems is analyzed. The effect of the natural surfactants in presence or in absence of electrolytes is also analyzed. The procedures followed in order to obtain the optimal conditions of formulation and formation of bitumen in water emulsions, are discussed and the effect of some parameters on the mean droplet diameter and distribution are also considered. It was found that keeping constant mixing speed and time of mixing, the mean droplet diameter decreases as the bitumen concentration increases. Emulsion stability, which can be monitored by following the changes in mean droplet diameters and viscosity as a function of the storage time, is deeply affected by the type and concentration of surfactant.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 3","pages":"216-34"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41008811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hematologic values among Warao indians with tuberculosis from the Orinoco Delta of Venezuela. 委内瑞拉奥里诺科河三角洲瓦劳印第安人肺结核患者的血液学价值。
Acta cientifica venezolana Pub Date : 2003-01-01
Zaida Araujo, Carlos Fernández de Larrea, Diana López, Cecil Fandiño, Merlin Chirinos, Jacinto Convit, Iraida Debora, Jacobus de Waard
{"title":"Hematologic values among Warao indians with tuberculosis from the Orinoco Delta of Venezuela.","authors":"Zaida Araujo,&nbsp;Carlos Fernández de Larrea,&nbsp;Diana López,&nbsp;Cecil Fandiño,&nbsp;Merlin Chirinos,&nbsp;Jacinto Convit,&nbsp;Iraida Debora,&nbsp;Jacobus de Waard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tuberculosis (TB) is a public health problem in Venezuelan indian communities. This study describes differences in hematological parameters in TB patients from two populations, Warao indians (WP) and creoles (CP). Control groups included Warao adults (WC) and children (WCh) as well as creole adults (CC). The results showed that the WP and WCh had significantly lower hemoglobin (Hb) levels than the WC and CC groups. Warao patients and two Warao control groups had significantly lower concentrations of median corpuscular Hb (MCHC) than the CP and CC groups. Regarding leucocyte indices, we observed a significant increament in the monocytes percentage in WP, WC and WCh, compared to CP and CC. In contrast, the neutrophils percentage was significantly reduced in all the Warao groups compared with the creole groups. Both WP and CP patient groups had higher platelet counts than those of the WC and CC groups. In relation to the body mass index (BMI), used as nutritional status indicator in Warao indians, we observed that the highest BMI was obtained in the adolescent group; with a continuous decreased with age. In conclusion, both WP and WCh presented decreased levels of Hb with erythrocytic hypochromia. Similar to the WCh, indian adults, even in the absence of the disease, presented a formula of white blood cells characterized by monocytosis, high percentage of lymphocytes and low percentage of neutrophils.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 4","pages":"247-53"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41008814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pollination and pollinators in the vegetation of the coastal plain of Paraguaná, Falcón State, Venezuela]. [委内瑞拉Falcón巴拉圭沿海平原植被的授粉和传粉媒介]。
Acta cientifica venezolana Pub Date : 2003-01-01
Luis José Lemus-Jiménez, Nelson Ramírez
{"title":"[Pollination and pollinators in the vegetation of the coastal plain of Paraguaná, Falcón State, Venezuela].","authors":"Luis José Lemus-Jiménez,&nbsp;Nelson Ramírez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pollination systems and plant-pollinator dynamics were studied for 51 plant species according to life form, vegetation type, and flowering phenology in the Paraguaná peninsula, Venezuela. A total of 43 species of floral visitors were recorded from which only 33 (76.7%) were effective pollinators and ten only visitors. Pollinator fauna consisted only of insects. Six pollinating agent classes were identified in the area of study. Pollinating bees were the most important class (35.1%), followed by butterflies (24.3%) and flies (13.5%). This trend was similar for the psamophilous and mangrove vegetation, but pollinating wasps were the third in importance in the littoral vegetation. Temporal distribution of pollinating agent classes showed a peak during the flowering peak, and during the lowest level of rainfall in the locality. Pollination systems were mostly polyphilous (62.7%) followed by monophilous (27.4%), and oligophilous species (7.8%). This trend was found to be similar for the different vegetation types and life forms. In a similar way, pollinator agents were mainly polytropic (60.4%), followed by monotropic (24.6%) and oligotropic species (14.8%). Plant species/pollinator species ratio was close to one for all vegetation types in the Paraguaná peninsula. Besides, the average number of pollinator species per plant species was 2.2, and the average number of plant species pollinated per insect species was 2.7. Plant species/pollinator species ratio and the average values of pollinator and plant species indicate a diffuse and symmetric relation between pollinator and plant species. These results are discussed in the context of the dynamics of pollination.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 2","pages":"97-114"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24405524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Establisment of a genetic transformation method of coffee (Coffea arabica cv. Catimor) and incorporation of bar gene for ammonium glufosinate resistance]. 咖啡(Coffea arabica cv.)遗传转化方法的建立。[Catimor]和bar基因的掺入对草铵膦抗性的影响。
Acta cientifica venezolana Pub Date : 2003-01-01
Rafael Fernández Da Silva
{"title":"[Establisment of a genetic transformation method of coffee (Coffea arabica cv. Catimor) and incorporation of bar gene for ammonium glufosinate resistance].","authors":"Rafael Fernández Da Silva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to establish a successful method of genetic transformation in Coffea arabica cv. Catimor, different conditions of generation and electroporation were evaluated on different plant tissues. Cell suspension system was improved using one hormone only (BA), obtaining high yields of primary and secondary somatic embryo production. For selection of viable and potentially transformed cells, MTT (1%) method and ammonium glufosinate concentration (1 mg/L in leaf, callus and embryos; and 5 mg/L in cells) were established. Different conditions were evaluated to electroporate different explants (embryogenic callus, vitroplants leaves, globular and torpedo embryos). The highest gus gene expression percentage by explant were found on enzymatic treated tissues at 375 V/cm in callus, and at 625 V/cm in leaves and embryos. Torpedo embryos cultured on liquid medium were the only type of tissue that could regenerate into plants, where secondary somatic embryos were obtained. Those embryos were positive to the gus gene histochemical test and to the gus and bar genes amplification on a PCR reaction.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 4","pages":"284-7"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40931500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[An approach to the cardiovascular technology through the interdisciplinarity: a Latin American necessity]. [通过跨学科研究心血管技术的方法:拉丁美洲的必要性]。
Acta cientifica venezolana Pub Date : 2003-01-01
John Bustamante
{"title":"[An approach to the cardiovascular technology through the interdisciplinarity: a Latin American necessity].","authors":"John Bustamante","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The progresses obtained in the cardiovascular medicine during the last years come to transform the content and the practice of the profession. These advances are consequence of the contribution of basic disciplines like the physics, the chemistry and sciences of the information. Thanks to those disciplines, which establish narrow bonds to each other, appear in the language the transdisciplinary sciences like the biophysics and the biochemistry, an approach between biological and the inorganic thing; as well as the interdisciplinary techniques of the biomedical engineering, whose work move in the medical surroundings using tools of engineering, like the bioinstrumentation, the biomechanics, the bioelectronic and the biomaterials. With these set of tools, it has been possible to extend the diagnoses methods as well as the therapeutic ones in the cardiovascular area, improving substantially the quality of life of the patients. As a result of it, the doctor-engineer encounter becomes transcendent, increasing the dialogue between both disciplines; in what must take part professionals of wide diversity of areas: cardiologists, cardiovascular surgeons, mechanical engineers, electronics engineers, industrial systems engineers, physicists, designers, among others; contributing each one in its field of the knowledge, but coming together towards a same axis of action.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 1","pages":"12-7"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40828805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[50 years old of the Luis Roche Foundation]. [路易斯罗氏基金会成立50年]。
Acta cientifica venezolana Pub Date : 2003-01-01
Abraham Levy-Benshimol
{"title":"[50 years old of the Luis Roche Foundation].","authors":"Abraham Levy-Benshimol","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 2","pages":"85-6"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24405522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New late-intensification schedules for cancer treatments. 癌症治疗的新晚期强化计划。
Acta cientifica venezolana Pub Date : 2003-01-01
Jorge A González, Harold P de Vladar, Morella Rebolledo
{"title":"New late-intensification schedules for cancer treatments.","authors":"Jorge A González,&nbsp;Harold P de Vladar,&nbsp;Morella Rebolledo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The nonlinear Gompertz equation that describes the evolutions of tumors under different treatments was investigated. It was shown that late logarithmic intensification asymptotically reduces the tumor cell population to zero. Using the same total amount of therapy, the schedule following a logarithmic function produces a larger reduction of tumor cell population than the schedule using a therapy with constant intensity. On the other hand, a logarithmic intensification should be more tolerable by the patients than a faster temporal growth therapy. We have shown that during the treatment the dose intensity should not be decreased at any time while the therapy is applied, because this will allow the tumor to relapse. The therapy intensity should be continuously increased as possible. We have solved an optimization problem for several late intensification treatments by the constraints of the total dose and the maximum individual (or daily) dose. Based on our results, we have designed new chemotherapy and radiotherapy treatments.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 4","pages":"263-73"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40931498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Biovolume of some centric diatoms from the northeastern continental shelf of Venezuela]. [委内瑞拉东北大陆架一些中心硅藻的生物量]。
Acta cientifica venezolana Pub Date : 2003-01-01
Balbina M Lugo-Vizcaino, José R Díaz-Ramos, Isaac G Sánchez-Suárez
{"title":"[Biovolume of some centric diatoms from the northeastern continental shelf of Venezuela].","authors":"Balbina M Lugo-Vizcaino,&nbsp;José R Díaz-Ramos,&nbsp;Isaac G Sánchez-Suárez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Biovolume variation of twelve centric diatom species from eight natural habitats of the northeastem continental shelf of Venezuela were analyzed. Also, the morphometric variable that exerts the greatest influence on the biovolume was determined. Samples were collected with a net (mesh 36 microns), or with a Niskin bottle (5 l) and fixed with neutralized formaldehyde (4%). Water temperature and salinity were measured. The species studied were: Detonula sp., Skeletonema costatum, Lauderia annulata, Pseudoguinardia recta, Cerataulina pelagica, Helicotheca tamesis, Rhizosolenia styliformis, Proboscia alata, Guinardia flaccida, G. striata, Dactyliosolen fragilissimus y Leptocylindrus danicus. Forty individuals of each species from each locality were isolated and measured with a Leitz Wetzlar binocular microscope with an ocular micrometer, magnified 400X. A one-way ANOVA showed the existence of highly significant differences (p < 0.001) in the biovolume of the species regarded with its locality. These differences could be due to: (a) temporal differences in sample collection: (b) the existence of populations in different phases of their vital cycles; (c) genetic differences; (d) and differences in the physical-chemical environment at each locality. The diameter was the morphometric variable exhibiting the largest positive correlation (r > or = 0.77, p < 0.001) with biovolume for all species, except for H. tamesis. In the latter, the apical axis (or side) exhibited the best correlation with biovolume (r = 0.94, p < 0.001). The high correlation between the diameter and/or the apical axis with the biovolumen suggests that the latter could be predicted from these morphometric variables with great reliability in these species.</p>","PeriodicalId":75378,"journal":{"name":"Acta cientifica venezolana","volume":"54 2","pages":"88-96"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24405523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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