World journal of clinical pediatrics最新文献

{"title":"Various aspects of hearing loss in newborns: A narrative review.","authors":"Raid M Al-Ani","doi":"10.5409/wjcp.v12.i3.86","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i3.86","url":null,"abstract":"<p><p>Hearing loss is considered the most common birth defect. The estimated prevalence of moderate and severe hearing loss in a normal newborn is 0.1%-0.3%, while the prevalence is 2%-4% in newborns admitted to the newborn intensive care unit. Neonatal hearing loss can be congenital (syndromic or non-syndromic) or acquired such as ototoxicity. In addition, the types of hearing loss can be conductive, sensorineural, or mixed. Hearing is vital for the acquisition of language and learning. Therefore, early detection and prompt treatment are of utmost importance in preventing the unwanted sequel of hearing loss. The hearing screening program is mandatory in many nations, especially for high-risk newborns. An automated auditory brainstem response test is used as a screening tool in newborns admitted to the newborn intensive care unit. Moreover, genetic testing and screening for cytomegalovirus in newborns are essential in identifying the cause of hearing loss, particularly, mild and delayed onset types of hearing loss. We aimed to update the knowledge on the various aspects of hearing loss in newborns with regard to the epidemiology, risk factors, causes, screening program, investigations, and different modalities of treatment.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 3","pages":"86-96"},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e9/c8/WJCP-12-86.PMC10278076.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9709206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>IFIH1</i> and <i>DDX58</i> gene variants in pediatric rheumatic diseases.","authors":"Rinat Raupov,&nbsp;Evgeny Suspitsin,&nbsp;Konstantin Belozerov,&nbsp;Tatiana Gabrusskaya,&nbsp;Mikhail Kostik","doi":"10.5409/wjcp.v12.i3.107","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i3.107","url":null,"abstract":"<p><strong>Background: </strong>The <i>IFIH1</i> gene codes the MDA5 protein and the <i>DDX58</i> gene codes the RIG-I receptor. Both proteins are parts of the interferon (IFN) I signaling pathway and are responsible for antiviral defense and innate immune response. IFIH1 and DDX58 polymorphisms are associated with a spectrum of autoimmune diseases. Rare gain-of-function IFIH1 mutations have been found in Singleton-Merten and Aicardi-Goutières syndrome, while DDX58 mutation can cause atypical Singleton-Merten syndrome.</p><p><strong>Aim: </strong>To characterize children with pediatric rheumatic diseases (PRD) carrying <i>DDX58</i> or <i>IFIH1</i> variants.</p><p><strong>Methods: </strong>Clinical exome sequencing was performed on 92 children with different PRD. <i>IFIH1</i> and <i>DDX58</i> variants have been detected in 14 children. IFN-I score has been analyzed and the clinical characteristics of patients have been studied.</p><p><strong>Results: </strong>A total of seven patients with systemic lupus erythematosus (SLE) (<i>n</i> = 2), myelodysplastic syndrome with SLE features at the onset of the disease (<i>n</i> = 1), mixed connective tissue disease (MCTD) (<i>n</i> = 1), undifferentiated systemic autoinflammatory disease (uSAID) (<i>n</i> = 3) have 5 different variants of the <i>DDX58</i> gene. A common non-pathogenic variant p.D580E has been found in five children. A rare variant of uncertain significance (VUS) p.N354S was found in one patient with uSAID, a rare likely non-pathogenic variant p.E37K in one patient with uSAID, and a rare likely pathogenic variant p.Cys864fs in a patient with SLE. Elevated IFN-I score was detected in 6 of 7 patients with <i>DDX58</i> variants. Seven patients had six different <i>IFIH1</i> variants. They were presented with uSAID (<i>n</i> = 2), juvenile dermatomyositis (JDM) (<i>n</i> = 1), SLE-like disease (<i>n</i> = 1), Periodic fever with aphthous stomatitis, pharyngitis, and adenitis syndrome (<i>n</i> = 1), and systemic onset juvenile idiopathic arthritis (<i>n</i> = 1). Three patients have VUS p.E627X, one patient has benign variant p.I923V. Rare VUS p.R595H was detected in the JDM patient. Another rare VUS p.L679Ifs*2 and previously not reported variant p.V599Ffs*5 were detected in the patient with uSAID. One patient with uSAID has rare VUS p.T520A. All patients had elevated IFN-I scores.</p><p><strong>Conclusion: </strong>Rare compound-heterozygous IFIH1 variant (p.L679Ifs*2 and p.V599Ffs*5), heterozygous IFIH1 variant (p.T520A) and heterozygous DDX58 variant (p.Cys864fs) are probably disease causative for uSAID and SLE. The majority of patients with different <i>DDX58</i> and <i>IFI1</i> variants had hyperactivation of the IFN I signaling pathway.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 3","pages":"107-114"},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/62/9b/WJCP-12-107.PMC10278078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9709212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging role of computed tomography coronary angiography in evaluation of children with Kawasaki disease.","authors":"Manphool Singhal,&nbsp;Rakesh Kumar Pilania,&nbsp;Pankaj Gupta,&nbsp;Nameirakpam Johnson,&nbsp;Surjit Singh","doi":"10.5409/wjcp.v12.i3.97","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i3.97","url":null,"abstract":"<p><p>Coronary artery abnormalities are the most important complications in children with Kawasaki disease (KD). Two-dimensional transthoracic echocardiography currently is the standard of care for initial evaluation and follow-up of children with KD. However, it has inherent limitations with regard to evaluation of mid and distal coronary arteries and, left circumflex artery and the poor acoustic window in older children often makes evaluation difficult in this age group. Catheter angiography (CA) is invasive, has high radiation exposure and fails to demonstrate abnormalities beyond lumen. The limitations of echocardiography and CA necessitate the use of an imaging modality that overcomes these problems. In recent years advances in computed tomography technology have enabled explicit evaluation of coronary arteries along their entire course including major branches with optimal and acceptable radiation exposure in children. Computed tomography coronary angiography (CTCA) can be performed during acute as well as convalescent phases of KD. It is likely that CTCA may soon be considered the reference standard imaging modality for evaluation of coronary arteries in children with KD.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 3","pages":"97-106"},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/d8/WJCP-12-97.PMC10278081.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10086648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatric disorders and caregiver burden in children with transfusion dependent β-thalassaemia and their caregivers.","authors":"Samiksha Sahu,&nbsp;Amit Agrawal,&nbsp;Jyotsna Shrivastava,&nbsp;Sudhir Tonk","doi":"10.5409/wjcp.v12.i3.125","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i3.125","url":null,"abstract":"<p><strong>Background: </strong>Children with thalassemia need care from the first years of life owing to the physical and psychological effects of their disorder. Thalassemia is a concern not only for the children's physical health but also the mental health of themselves and their caregivers.</p><p><strong>Aim: </strong>To screen the psychosocial problems and assessment of psychiatric morbidities among thalassaemic children and their caretakers, along with an assessment of caregiver burden in them.</p><p><strong>Methods: </strong>In this observational cross-sectional study, children with transfusion-dependent thalassemia, were included and were assessed for psychiatric morbidity and global functioning. Their parents were assessed for psychiatric morbidity and the caregiver burden they faced. All the parents completed two different questionnaires to assess their knowledge about the psycho-social functioning [using Pediatric Symptom Checklist-35 (PSC-35)] of their children and the level of the burden faced by them by Caregiver Burden Scale (CBS).</p><p><strong>Results: </strong>A total of 46 children (28 boys and 18 girls) with transfusion-dependent thalassemia with a mean age of 8.83 ± 2.70 years and 46 parents (12 fathers and 34 mothers) were included in this study. More than 32 children had some psychosocial problems on screening by PSC-35. On assessment by CBS moderate caregiver burden was perceived in domains of general strain, isolation, disappointment, emotional involvement, and environment. A total of 65.3% of children and 62.7% of parents were diagnosed with psychiatric problems.</p><p><strong>Conclusion: </strong>Thalassemia affects not only the persons with the disorder but also their caregivers in several aspects, including their psychosocial well-being. This study emphasizes the role of a supportive group in the psychological well-being of caregivers, which could be used to prevent the pathological effects of caregiver burden and enhance their psychological well-being through counselling.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 3","pages":"125-132"},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2b/5d/WJCP-12-125.PMC10278083.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9701036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seronegative autoimmune hepatitis in childhood.","authors":"Ali Islek,&nbsp;Gokhan Tumgor","doi":"10.5409/wjcp.v12.i3.77","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i3.77","url":null,"abstract":"<p><p>Comprehensive guidelines on seropositive autoimmune hepatitis have been published for both adults and children, although these guidelines comprise only limited knowledge about seronegative autoimmune hepatitis. Autoimmune hepatitis presents as an acute or chronic progressive disease and poor outcomes are inevitable if left untreated. The absence of autoantibody positivity, hypergammaglobulinemia and lack of comprehensive algorithms makes seronegative autoimmune hepatitis a mysterious disease. In general, seronegative autoimmune hepatitis often presents with acute hepatitis, and its treatment and prognosis similar to seropositive autoimmune hepatitis. The present review focuses on the known characteristics of seronegative autoimmune hepatitis in childhood, and those of which current knowledge is vague.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 3","pages":"77-85"},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/de/3f/WJCP-12-77.PMC10278082.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9701040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with subsequent surgery after septic arthritis of the knee in children.","authors":"Jennifer Marie O'Donnell,&nbsp;Ernest Ekunseitan,&nbsp;Ishaan Swarup","doi":"10.5409/wjcp.v12.i2.38","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i2.38","url":null,"abstract":"<p><strong>Background: </strong>Septic arthritis of the knee in children is a challenging problem. Surgical debridement is an established treatment, but there is a paucity of literature on long-term prognosis.</p><p><strong>Aim: </strong>To determine the rates and factors associated with return to surgery (RTS) and readmission after index surgical debridement for septic arthritis of the knee in children.</p><p><strong>Methods: </strong>This is a retrospective cohort study that utilizes data from the Healthcare Cost and Utilization Project (HCUP). We included patients between ages 0 to 18 years that underwent surgical debridement for septic arthritis of the knee between 2005 and 2017. Demographic data included age, gender, race, hospital type and insurance type. Clinical data including index admission length of stay (LOS) and Charlson Comorbidity Index (CCI) were available from the HCUP database. Descriptive statistics were used to summarize the data and univariate and multivariate analyses were performed.</p><p><strong>Results: </strong>Nine-hundred thirty-two cases of pediatric septic knee were included. This cohort was 62.3% male, with mean age of 9.0 (± 6.1) years. Approximately 46% of patients were white and approximately half had Medicaid insurance. Thirty-six patients (3.6%) required RTS at a minimum of 2 year after index surgery, and 172 patients (18.5%) were readmitted at any point. The mean readmission LOS was 11.6(± 11.3) d. Higher CCI was associated with RTS (<i>P</i> = 0.041). There were no significant associations in age, gender, race, insurance type, or type of hospital to which patients presented. Multivariate analysis showed that both increased CCI (<i>P</i> = 0.008) and shorter LOS (<i>P</i> = 0.019) were predictive of RTS.</p><p><strong>Conclusion: </strong>Septic arthritis of the knee is an important condition in children. The CCI was associated with RTS at a minimum of 2 years after index procedure. No association was found with age, gender, race, insurance type, or hospital type. Shorter LOS and CCI were associated with RTS in multivariate analysis. Overall, risk of subsequent surgery and readmission after pediatric septic knee arthritis is low, and CCI and shorter LOS are predictive of RTS.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 2","pages":"38-44"},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f4/58/WJCP-12-38.PMC10075021.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher rates of autism and attention deficit/hyperactivity disorder in American children: Are food quality issues impacting epigenetic inheritance?","authors":"Renee J Dufault,&nbsp;Raquel A Crider,&nbsp;Richard C Deth,&nbsp;Roseanne Schnoll,&nbsp;Steven G Gilbert,&nbsp;Walter J Lukiw,&nbsp;Amanda L Hitt","doi":"10.5409/wjcp.v12.i2.25","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i2.25","url":null,"abstract":"<p><p>In the United States, schools offer special education services to children who are diagnosed with a learning or neurodevelopmental disorder and have difficulty meeting their learning goals. Pediatricians may play a key role in helping children access special education services. The number of children ages 6-21 in the United States receiving special education services increased 10.4% from 2006 to 2021. Children receiving special education services under the autism category increased 242% during the same period. The demand for special education services for children under the developmental delay and other health impaired categories increased by 184% and 83% respectively. Although student enrollment in American schools has remained stable since 2006, the percentage distribution of children receiving special education services nearly tripled for the autism category and quadrupled for the developmental delay category by 2021. Allowable heavy metal residues remain persistent in the American food supply due to food ingredient manufacturing processes. Numerous clinical trial data indicate heavy metal exposures and poor diet are the primary epigenetic factors responsible for the autism and attention deficit hyperactivity disorder epidemics. Dietary heavy metal exposures, especially inorganic mercury and lead may impact gene behavior across generations. In 2021, the United States Congress found heavy metal residues problematic in the American food supply but took no legislative action. Mandatory health warning labels on select foods may be the only way to reduce dietary heavy metal exposures and improve child learning across generations.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 2","pages":"25-37"},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0e/72/WJCP-12-25.PMC10075020.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaccination coverage in children with juvenile idiopathic arthritis, inflammatory bowel diseases, and healthy peers: Cross-sectional electronic survey data.","authors":"Elizaveta Makarova,&nbsp;Aygul Khabirova,&nbsp;Natalia Volkova,&nbsp;Tatiana Gabrusskaya,&nbsp;Natalia Ulanova,&nbsp;Larisa Sakhno,&nbsp;Maria Revnova,&nbsp;Mikhail Kostik","doi":"10.5409/wjcp.v12.i2.45","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i2.45","url":null,"abstract":"<p><strong>Background: </strong>Patients with immune-mediated diseases, such as juvenile idiopathic arthritis (JIA) and inflammatory bowel disease (IBD) are at increased risk of developing infections, due to disease-related immune dysfunction and applying of immunosuppressive drugs.</p><p><strong>Aim: </strong>To evaluate vaccine coverage in patients with IBD and JIA, and compare it with healthy children.</p><p><strong>Methods: </strong>In the cross-sectional study we included the data from a questionnaire survey of 190 Legal representatives of children with JIA (<i>n</i> = 81), IBD (<i>n</i> = 51), and healthy children (HC, <i>n</i> = 58). An electronic online questionnaire was created for the survey.</p><p><strong>Results: </strong>There were female predominance in JIA patients and younger onset age. Parents of JIA had higher education levels. Employment level and family status were similar in the three studied groups. Patients with JIA and IBD had lower vaccine coverage, without parental rejection of vaccinations in IBD, compare to JIA and healthy controls. The main reason for incomplete vaccination was medical conditions in IBD and JIA. IBD patients had a lower rate of normal vaccine-associated reactions compared to JIA and HC. The encouraging role of physicians for vaccinations was the lowest in JIA patients. IBD patients had more possibilities to check antibodies before immune-suppressive therapy and had more supplementary vaccinations compared to JIA and HC.</p><p><strong>Conclusion: </strong>JIA and IBD patients had lower vaccine coverage compared to HC. Physicians' encouragement of vaccination and the impossibility of discus about future vaccinations and their outcomes seemed the main factors for patients with immune-mediated diseases, influencing vaccine coverage. Further investigations are required to understand the reasons for incomplete vaccinations and improve vaccine coverage in both groups, especially in rheumatic disease patients. The approaches that stimulate vaccination in healthy children are not always optimal in children with immune-mediated diseases. It is necessary to provide personalized vaccine-encouraging strategies for parents of chronically ill children with the following validation of these technics.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 2","pages":"45-56"},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/c2/WJCP-12-45.PMC10075019.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Play therapy in children with autism: Its role, implications, and limitations.","authors":"Reem Elbeltagi,&nbsp;Mohammed Al-Beltagi,&nbsp;Nermin Kamal Saeed,&nbsp;Rawan Alhawamdeh","doi":"10.5409/wjcp.v12.i1.1","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i1.1","url":null,"abstract":"<p><p>Play is a pleasurable physical or mental activity that enhances the child's skills involving negotiation abilities, problem-solving, manual dexterity, sharing, decision-making, and working in a group. Play affects all the brain's areas, structures, and functions. Children with autism have adaptive behavior, adaptive response, and social interaction limitations. This review explores the different applications of play therapy in helping children with autism disorder. Play is usually significantly impaired in children with autism. Play therapy is mainly intended to help children to honor their unique mental abilities and developmental levels. The main aim of play therapy is to prevent or solve psychosocial difficulties and achieve optimal child-healthy growth and development. Play therapy helps children with autism to engage in play activities of their interest and choice to express themselves in the most comfortable ways. It changes their way of self-expression from unwanted behaviors to more non-injurious expressive behavior using toys or activities of their choice as their words. Play therapy also helps those children to experience feeling out various interaction styles. Every child with autism is unique and responds differently. Therefore, different types of intervention, like play therapy, could fit the differences in children with autism. Proper evaluation of the child is mandatory to evaluate which type fits the child more than the others. This narrative review revised the different types of play therapy that could fit children with autism in an evidence-based way. Despite weak evidence, play therapy still has potential benefits for patients and their families.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 1","pages":"1-22"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dd/30/WJCP-12-1.PMC9850869.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10636155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adipocytokine profile in children with Kawasaki disease.","authors":"Beuy Joob,&nbsp;Viroj Wiwanitkit","doi":"10.5409/wjcp.v12.i1.23","DOIUrl":"https://doi.org/10.5409/wjcp.v12.i1.23","url":null,"abstract":"<p><p>This letter to editor discusses on the publication on adipocytokine profile in children with Kawasaki disease. Concerns on confounding factors are raised and discussed.</p>","PeriodicalId":75338,"journal":{"name":"World journal of clinical pediatrics","volume":"12 1","pages":"23-24"},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/ba/WJCP-12-23.PMC9850870.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10636154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}