Statistical atlases and computational models of the heart. STACOM (Workshop)最新文献

Statistical shape analysis of the tricuspid valve in hypoplastic left heart sydrome. 发育不全左心综合征三尖瓣的统计形状分析。

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-09-01 Epub Date: 2022-01-01 DOI: 10.1007/978-3-030-93722-5_15

Jared Vicory, Christian Herz, David Allemang, Hannah H Nam, Alana Cianciulli, Chad Vigil, Ye Han, Andras Lasso, Matthew A Jolley, Beatriz Paniagua

{"title":"Statistical shape analysis of the tricuspid valve in hypoplastic left heart sydrome.","authors":"Jared Vicory, Christian Herz, David Allemang, Hannah H Nam, Alana Cianciulli, Chad Vigil, Ye Han, Andras Lasso, Matthew A Jolley, Beatriz Paniagua","doi":"10.1007/978-3-030-93722-5_15","DOIUrl":"10.1007/978-3-030-93722-5_15","url":null,"abstract":"Hypoplastic left heart syndrome (HLHS) is a congenital heart disease characterized by incomplete development of the left heart. Children with HLHS undergo a series of operations which result in the tricuspid valve (TV) becoming the only functional atrioventricular valve. Some of those patients develop tricuspid regurgitation which is associated with heart failure and death and necessitates further surgical intervention. Repair of the regurgitant TV, and understanding the connections between structure and function of this valve remains extremely challenging. Adult cardiac populations have used 3D echocardiography (3DE) combined with computational modeling to better understand cardiac conditions affecting the TV. However, these structure-function analyses rely on simplistic point-based techniques that do not capture the leaflet surface in detail, nor do they allow robust comparison of shapes across groups. We propose using statistical shape modeling and analysis of the TV using Spherical Harmonic Representation Point Distribution Models (SPHARM-PDM) in order to generate a reproducible representation, which in turn enables high dimensional low sample size statistical analysis techniques such as principal component analysis and distance weighted discrimination. Our initial results suggest that visualization of the differences in regurgitant vs. non-regurgitant valves can precisely locate populational structural differences as well as how an individual regurgitant valve differs from the mean shape of functional valves. We believe that these results will support the creation of modern image-based modeling tools, and ultimately increase the understanding of the relationship between valve structure and function needed to inform and improve surgical planning in HLHS.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"13131 ","pages":"132-140"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788948/pdf/nihms-1759249.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39866544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Statistical Shape Modeling of Biventricular Anatomy with Shared Boundaries 具有共享边界的双心室解剖统计形状建模

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-09-01 DOI: 10.48550/arXiv.2209.02706

Krithika S. Iyer, A. Morris, B. Zenger, Karthik Karnath, Benjamin A Orkild, O. Korshak, Shireen Elhabian

{"title":"Statistical Shape Modeling of Biventricular Anatomy with Shared Boundaries","authors":"Krithika S. Iyer, A. Morris, B. Zenger, Karthik Karnath, Benjamin A Orkild, O. Korshak, Shireen Elhabian","doi":"10.48550/arXiv.2209.02706","DOIUrl":"https://doi.org/10.48550/arXiv.2209.02706","url":null,"abstract":"Statistical shape modeling (SSM) is a valuable and powerful tool to generate a detailed representation of complex anatomy that enables quantitative analysis and the comparison of shapes and their variations. SSM applies mathematics, statistics, and computing to parse the shape into a quantitative representation (such as correspondence points or landmarks) that will help answer various questions about the anatomical variations across the population. Complex anatomical structures have many diverse parts with varying interactions or intricate architecture. For example, the heart is a four-chambered anatomy with several shared boundaries between chambers. Coordinated and efficient contraction of the chambers of the heart is necessary to adequately perfuse end organs throughout the body. Subtle shape changes within these shared boundaries of the heart can indicate potential pathological changes that lead to uncoordinated contraction and poor end-organ perfusion. Early detection and robust quantification could provide insight into ideal treatment techniques and intervention timing. However, existing SSM approaches fall short of explicitly modeling the statistics of shared boundaries. In this paper, we present a general and flexible data-driven approach for building statistical shape models of multi-organ anatomies with shared boundaries that captures morphological and alignment changes of individual anatomies and their shared boundary surfaces throughout the population. We demonstrate the effectiveness of the proposed methods using a biventricular heart dataset by developing shape models that consistently parameterize the cardiac biventricular structure and the interventricular septum (shared boundary surface) across the population data.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"52 1","pages":"302-316"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73727083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Spatiotemporal Cardiac Statistical Shape Modeling: A Data-Driven Approach 时空心脏统计形状建模:数据驱动的方法

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-09-01 DOI: 10.48550/arXiv.2209.02736

Jadie Adams, N. Khan, A. Morris, Shireen Elhabian

{"title":"Spatiotemporal Cardiac Statistical Shape Modeling: A Data-Driven Approach","authors":"Jadie Adams, N. Khan, A. Morris, Shireen Elhabian","doi":"10.48550/arXiv.2209.02736","DOIUrl":"https://doi.org/10.48550/arXiv.2209.02736","url":null,"abstract":"Clinical investigations of anatomy's structural changes over time could greatly benefit from population-level quantification of shape, or spatiotemporal statistic shape modeling (SSM). Such a tool enables characterizing patient organ cycles or disease progression in relation to a cohort of interest. Constructing shape models requires establishing a quantitative shape representation (e.g., corresponding landmarks). Particle-based shape modeling (PSM) is a data-driven SSM approach that captures population-level shape variations by optimizing landmark placement. However, it assumes cross-sectional study designs and hence has limited statistical power in representing shape changes over time. Existing methods for modeling spatiotemporal or longitudinal shape changes require predefined shape atlases and pre-built shape models that are typically constructed cross-sectionally. This paper proposes a data-driven approach inspired by the PSM method to learn population-level spatiotemporal shape changes directly from shape data. We introduce a novel SSM optimization scheme that produces landmarks that are in correspondence both across the population (inter-subject) and across time-series (intra-subject). We apply the proposed method to 4D cardiac data from atrial-fibrillation patients and demonstrate its efficacy in representing the dynamic change of the left atrium. Furthermore, we show that our method outperforms an image-based approach for spatiotemporal SSM with respect to a generative time-series model, the Linear Dynamical System (LDS). LDS fit using a spatiotemporal shape model optimized via our approach provides better generalization and specificity, indicating it accurately captures the underlying time-dependency.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"58 1","pages":"143-156"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76043133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Statistical Shape Modeling of Biventricular Anatomy with Shared Boundaries. 具有共享边界的双心室解剖统计形状建模

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-09-01 Epub Date: 2023-01-28 DOI: 10.1007/978-3-031-23443-9_28

Krithika Iyer, Alan Morris, Brian Zenger, Karthik Karanth, Benjamin A Orkild, Oleksandre Korshak, Shireen Elhabian

{"title":"Statistical Shape Modeling of Biventricular Anatomy with Shared Boundaries.","authors":"Krithika Iyer, Alan Morris, Brian Zenger, Karthik Karanth, Benjamin A Orkild, Oleksandre Korshak, Shireen Elhabian","doi":"10.1007/978-3-031-23443-9_28","DOIUrl":"10.1007/978-3-031-23443-9_28","url":null,"abstract":"Statistical shape modeling (SSM) is a valuable and powerful tool to generate a detailed representation of complex anatomy that enables quantitative analysis and the comparison of shapes and their variations. SSM applies mathematics, statistics, and computing to parse the shape into a quantitative representation (such as correspondence points or landmarks) that will help answer various questions about the anatomical variations across the population. Complex anatomical structures have many diverse parts with varying interactions or intricate architecture. For example, the heart is a four-chambered anatomy with several shared boundaries between chambers. Coordinated and efficient contraction of the chambers of the heart is necessary to adequately perfuse end organs throughout the body. Subtle shape changes within these shared boundaries of the heart can indicate potential pathological changes that lead to uncoordinated contraction and poor end-organ perfusion. Early detection and robust quantification could provide insight into ideal treatment techniques and intervention timing. However, existing SSM approaches fall short of explicitly modeling the statistics of shared boundaries. In this paper, we present a general and flexible data-driven approach for building statistical shape models of multi-organ anatomies with shared boundaries that captures morphological and alignment changes of individual anatomies and their shared boundary surfaces throughout the population. We demonstrate the effectiveness of the proposed methods using a biventricular heart dataset by developing shape models that consistently parameterize the cardiac biventricular structure and the interventricular septum (shared boundary surface) across the population data.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"13593 ","pages":"302-316"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10103081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9379519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Atlas-Based Analysis of Biventricular Mechanics in Tetralogy of Fallot. 基于图谱的法洛氏四联症双心室力学分析。

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-09-01 Epub Date: 2023-01-28 DOI: 10.1007/978-3-031-23443-9_11

Sachin Govil, Sanjeet Hegde, James C Perry, Jeffrey H Omens, Andrew D McCulloch

{"title":"An Atlas-Based Analysis of Biventricular Mechanics in Tetralogy of Fallot.","authors":"Sachin Govil, Sanjeet Hegde, James C Perry, Jeffrey H Omens, Andrew D McCulloch","doi":"10.1007/978-3-031-23443-9_11","DOIUrl":"10.1007/978-3-031-23443-9_11","url":null,"abstract":"The current study proposes an efficient strategy for exploiting the statistical power of cardiac atlases to investigate whether clinically significant variations in ventricular shape are sufficient to explain corresponding differences in ventricular wall motion directly, or if they are indirect markers of altered myocardial mechanical properties. This study was conducted in a cohort of patients with repaired tetralogy of Fallot (rTOF) that face long-term right ventricular (RV) and/or left ventricular (LV) dysfunction as a consequence of adverse remodeling. Features of biventricular end-diastolic (ED) shape associated with RV apical dilation, LV dilation, RV basal bulging, and LV conicity correlated with components of systolic wall motion (SWM) that contribute most to differences in global systolic function. A finite element analysis of systolic biventricular mechanics was employed to assess the effect of perturbations in these ED shape modes on corresponding components of SWM. Perturbations to ED shape modes and myocardial contractility explained observed variation in SWM to varying degrees. In some cases, shape markers were partial determinants of systolic function and, in other cases, they were indirect markers for altered myocardial mechanical properties. Patients with rTOF may benefit from an atlas-based analysis of biventricular mechanics to improve prognosis and gain mechanistic insight into underlying myocardial pathophysiology.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"13593 ","pages":"112-122"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226763/pdf/nihms-1894267.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9908012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatiotemporal Cardiac Statistical Shape Modeling: A Data-Driven Approach. 时空心脏统计形状建模：数据驱动方法。

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-09-01 Epub Date: 2023-01-28 DOI: 10.1007/978-3-031-23443-9_14

Jadie Adams, Nawazish Khan, Alan Morris, Shireen Elhabian

{"title":"Spatiotemporal Cardiac Statistical Shape Modeling: A Data-Driven Approach.","authors":"Jadie Adams, Nawazish Khan, Alan Morris, Shireen Elhabian","doi":"10.1007/978-3-031-23443-9_14","DOIUrl":"10.1007/978-3-031-23443-9_14","url":null,"abstract":"Clinical investigations of anatomy's structural changes over time could greatly benefit from population-level quantification of shape, or spatiotemporal statistic shape modeling (SSM). Such a tool enables characterizing patient organ cycles or disease progression in relation to a cohort of interest. Constructing shape models requires establishing a quantitative shape representation (e.g., corresponding landmarks). Particle-based shape modeling (PSM) is a data-driven SSM approach that captures population-level shape variations by optimizing landmark placement. However, it assumes cross-sectional study designs and hence has limited statistical power in representing shape changes over time. Existing methods for modeling spatiotemporal or longitudinal shape changes require predefined shape atlases and pre-built shape models that are typically constructed cross-sectionally. This paper proposes a data-driven approach inspired by the PSM method to learn population-level spatiotemporal shape changes directly from shape data. We introduce a novel SSM optimization scheme that produces landmarks that are in correspondence both across the population (inter-subject) and across time-series (intra-subject). We apply the proposed method to 4D cardiac data from atrial-fibrillation patients and demonstrate its efficacy in representing the dynamic change of the left atrium. Furthermore, we show that our method outperforms an image-based approach for spatiotemporal SSM with respect to a generative time-series model, the Linear Dynamical System (LDS). LDS fit using a spatiotemporal shape model optimized via our approach provides better generalization and specificity, indicating it accurately captures the underlying time-dependency.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"13593 ","pages":"143-156"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9367175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-modal Latent-Space Self-alignment for Super-Resolution Cardiac MR Segmentation. 用于超分辨率心脏磁共振成像分割的多模态潜空间自对齐。

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-09-01 Epub Date: 2023-01-28 DOI: 10.1007/978-3-031-23443-9_3

Yu Deng, Yang Wen, Linglong Qian, Esther Puyol Anton, Hao Xu, Kuberan Pushparajah, Zina Ibrahim, Richard Dobson, Alistair Young

{"title":"Multi-modal Latent-Space Self-alignment for Super-Resolution Cardiac MR Segmentation.","authors":"Yu Deng, Yang Wen, Linglong Qian, Esther Puyol Anton, Hao Xu, Kuberan Pushparajah, Zina Ibrahim, Richard Dobson, Alistair Young","doi":"10.1007/978-3-031-23443-9_3","DOIUrl":"10.1007/978-3-031-23443-9_3","url":null,"abstract":"2D cardiac MR cine images provide data with a high signal-to-noise ratio for the segmentation and reconstruction of the heart. These images are frequently used in clinical practice and research. However, the segments have low resolution in the through-plane direction, and standard interpolation methods are unable to improve resolution and precision. We proposed an end-to-end pipeline for producing high-resolution segments from 2D MR images. This pipeline utilised a bilateral optical flow warping method to recover images in the through-plane direction, while a SegResNet automatically generated segments of the left and right ventricles. A multi-modal latent-space self-alignment network was implemented to guarantee that the segments maintain an anatomical prior derived from unpaired 3D high-resolution CT scans. On 3D MR angiograms, the trained pipeline produced high-resolution segments that preserve an anatomical prior derived from patients with various cardiovascular diseases.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"13593 ","pages":"26-35"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10148962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9402119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skeletal model-based analysis of the tricuspid valve in hypoplastic left heart syndrome. 基于骨骼模型的左心发育不全综合征三尖瓣分析。

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-01-01 DOI: 10.1007/978-3-031-23443-9_24

Jared Vicory, Christian Herz, Ye Han, David Allemang, Maura Flynn, Alana Cianciulli, Hannah H Nam, Patricia Sabin, Andras Lasso, Matthew A Jolley, Beatriz Paniagua

{"title":"Skeletal model-based analysis of the tricuspid valve in hypoplastic left heart syndrome.","authors":"Jared Vicory, Christian Herz, Ye Han, David Allemang, Maura Flynn, Alana Cianciulli, Hannah H Nam, Patricia Sabin, Andras Lasso, Matthew A Jolley, Beatriz Paniagua","doi":"10.1007/978-3-031-23443-9_24","DOIUrl":"10.1007/978-3-031-23443-9_24","url":null,"abstract":"Hypoplastic left heart syndrome (HLHS) is a congenital heart disease characterized by incomplete development of the left heart. Children with HLHS undergo a series of operations which result in the tricuspid valve (TV) becoming the only functional atrioventricular valve. Many HLHS patients develop tricuspid regurgitation and right ventricle enlargement which is associated with heart failure and death without surgical intervention on the valve. Understanding the connections between the geometry of the TV and its function remains extremely challenging and hinders TV repair planning. Traditional analysis methods rely on simple anatomical measures which do not capture information about valve geometry in detail. Recently, surface-based shape representations such as SPHARM-PDM have been shown to be useful for tasks such as discriminating between valves with normal or poor function. In this work we propose to use skeletal representations (s-reps), a more feature-rich geometric representation, for modeling the leaflets of the tricuspid valve. We propose an extension to previous s-rep fitting approaches to incorporate application-specific anatomical landmarks and population information to improve correspondence. We use several traditional statistical shape analysis techniques to evaluate the efficiency of this representation: using principal component analysis (PCA) we observe that it takes fewer modes of variation compared to boundary-based approaches to represent 90% of the population variation, while distance-weighted discrimination (DWD) shows that s-reps provide for more significant classification between valves with less regurgitation and those with more. These results show the power of using s-reps for modeling the relationship between structure and function of the tricuspid valve.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"13593 ","pages":"258-268"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949511/pdf/nihms-1869944.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9155638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous Segmentation and Motion Estimation of Left Ventricular Myocardium in 3D Echocardiography Using Multi-task Learning. 基于多任务学习的三维超声心动图左心室心肌同时分割和运动估计。

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2022-01-01 Epub Date: 2022-01-14 DOI: 10.1007/978-3-030-93722-5_14

Kevinminh Ta, Shawn S Ahn, John C Stendahl, Jonathan Langdon, Albert J Sinusas, James S Duncan

{"title":"Simultaneous Segmentation and Motion Estimation of Left Ventricular Myocardium in 3D Echocardiography Using Multi-task Learning.","authors":"Kevinminh Ta, Shawn S Ahn, John C Stendahl, Jonathan Langdon, Albert J Sinusas, James S Duncan","doi":"10.1007/978-3-030-93722-5_14","DOIUrl":"https://doi.org/10.1007/978-3-030-93722-5_14","url":null,"abstract":"Motion estimation and segmentation are both critical steps in identifying and assessing myocardial dysfunction, but are traditionally treated as unique tasks and solved as separate steps. However, many motion estimation techniques rely on accurate segmentations. It has been demonstrated in the computer vision and medical image analysis literature that both these tasks may be mutually beneficial when solved simultaneously. In this work, we propose a multi-task learning network that can concurrently predict volumetric segmentations of the left ventricle and estimate motion between 3D echocardiographic image pairs. The model exploits complementary latent features between the two tasks using a shared feature encoder with task-specific decoding branches. Anatomically inspired constraints are incorporated to enforce realistic motion patterns. We evaluate our proposed model on an in vivo 3D echocardiographic canine dataset. Results suggest that coupling these two tasks in a learning framework performs favorably when compared against single task learning and other alternative methods.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":" ","pages":"123-131"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221412/pdf/nihms-1816353.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40403664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Persistent Homology-Based Topological Loss Function for Multi-class CNN Segmentation of Cardiac MRI. 基于持续同源的拓扑损失函数在心脏MRI多类CNN分割中的应用。

Statistical atlases and computational models of the heart. STACOM (Workshop) Pub Date : 2020-01-01 Epub Date: 2021-01-29 DOI: 10.1007/978-3-030-68107-4_1

Nick Byrne, James R Clough, Giovanni Montana, Andrew P King

{"title":"A Persistent Homology-Based Topological Loss Function for Multi-class CNN Segmentation of Cardiac MRI.","authors":"Nick Byrne, James R Clough, Giovanni Montana, Andrew P King","doi":"10.1007/978-3-030-68107-4_1","DOIUrl":"https://doi.org/10.1007/978-3-030-68107-4_1","url":null,"abstract":"With respect to spatial overlap, CNN-based segmentation of short axis cardiovascular magnetic resonance (CMR) images has achieved a level of performance consistent with inter observer variation. However, conventional training procedures frequently depend on pixel-wise loss functions, limiting optimisation with respect to extended or global features. As a result, inferred segmentations can lack spatial coherence, including spurious connected components or holes. Such results are implausible, violating the anticipated topology of image segments, which is frequently known a priori. Addressing this challenge, published work has employed persistent homology, constructing topological loss functions for the evaluation of image segments against an explicit prior. Building a richer description of segmentation topology by considering all possible labels and label pairs, we extend these losses to the task of multi-class segmentation. These topological priors allow us to resolve all topological errors in a subset of 150 examples from the ACDC short axis CMR training data set, without sacrificing overlap performance.","PeriodicalId":74866,"journal":{"name":"Statistical atlases and computational models of the heart. STACOM (Workshop)","volume":"2020 ","pages":"3-13"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610940/pdf/EMS124653.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39080292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20