Sarah Matthews, Gary Peck, R. Reifer, M. Hyde, Burkhard Jansen, M. Skelsey
{"title":"Visual Assessment and Dermoscopy Enhanced by Non-invasive Genomic Testing","authors":"Sarah Matthews, Gary Peck, R. Reifer, M. Hyde, Burkhard Jansen, M. Skelsey","doi":"10.25251/skin.7.supp.171","DOIUrl":"https://doi.org/10.25251/skin.7.supp.171","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45778489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of Cutaneous Lesions in a Case of Blue Rubber Bleb Nevus Syndrome","authors":"S. Seck, Taylor A. Bullock, S. Khetarpal","doi":"10.25251/skin.7.2.16","DOIUrl":"https://doi.org/10.25251/skin.7.2.16","url":null,"abstract":"Blue rubber bleb nevus syndrome (BRBNS), sometimes called Bean syndrome, is a rare sporadic congenital vascular disorder characterized by multiple venous malformations in various organ systems, most commonly the skin and gastrointestinal tract. The presence of characteristic skin lesions is often the first suggestion of this diagnosis, though chronic anemia and intestinal bleeding are also commonly present. We report a case of a patient with painful lesions on the plantar surfaces of the feet and a new cutaneous growth on the left labia majora. The plantar lesions were treated with Nd:YAG laser and the lesion on the labia majora was removed with a shave biopsy.","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43213342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sunscreen Knowledge and Sun Protective Behaviors among Medical Students at a Southern US Institution","authors":"M. Olivet, Lauren C. S. Kole","doi":"10.25251/skin.7.2.3","DOIUrl":"https://doi.org/10.25251/skin.7.2.3","url":null,"abstract":"Literature has demonstrated that medical students have discrepancies in their knowledge and their execution of best practices concerning sun protection. Additionally, despite knowing the harms of tanning, medical students acknowledge that they desire tan skin. A survey was sent to medical students at a Southeastern institution to determine their knowledge of sun safety and their personal practices. The survey was distributed through institutional emails and student messaging applications. Current medical students at the home institution were eligible to complete the survey. The survey was designed with guidelines from the American Academy of Dermatology in mind. Chi-square analysis was performed by SPSS Version 28.0.1.1 (14). The majority of medical students are knowledgeable of best sun protective practices, though many students do not carry out these practices. For example, 88% of students know to reapply sunscreen every 2 hours; however, only 28% always reapply at the correct interval. Several demographic differences were present between self-reported race and gender groups in the knowledge, behaviors, and tanning questions. Medical students are knowledgeable of best practices for preventing sun damage; however, their personal behaviors can deviate and societal pressure for some students to have “tanned” skin is challenging to overcome.","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42506151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Migden, C. Schmults, N. Khushalani, A. Guminski, A. Chang, K. Lewis, G. Ansstas, S. Bowyer, B. Hughes, D. Schadendorf, B. Modi, L. Dunn, L. Flatz, A. Hauschild, Suk-Young Yoo, J. Booth, F. Seebach, I. Lowy, M. Fury, D. Rischin
{"title":"Phase 2 study of cemiplimab in patients with advanced cutaneous squamous cell carcinoma (CSCC): Final analysis from EMPOWER-CSCC-1 Groups 1, 2, and 3","authors":"M. Migden, C. Schmults, N. Khushalani, A. Guminski, A. Chang, K. Lewis, G. Ansstas, S. Bowyer, B. Hughes, D. Schadendorf, B. Modi, L. Dunn, L. Flatz, A. Hauschild, Suk-Young Yoo, J. Booth, F. Seebach, I. Lowy, M. Fury, D. Rischin","doi":"10.25251/skin.7.supp.176","DOIUrl":"https://doi.org/10.25251/skin.7.supp.176","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43771793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel Christensen, Colleen Powers, Chelsea S. Mockbee, R. Brodell
{"title":"Petaloid Seborrheic Dermatitis: A Variant Described Primarily in Skin of Color","authors":"Rachel Christensen, Colleen Powers, Chelsea S. Mockbee, R. Brodell","doi":"10.25251/skin.7.2.8","DOIUrl":"https://doi.org/10.25251/skin.7.2.8","url":null,"abstract":"Petaloid seborrheic dermatitis is a distinct variant of seborrheic dermatitis most commonly affecting patients with skin of color. It is characterized by arcuate coalescing lesions with fine scale and a raised border that symmetrically expands over the course of weeks in a seborrheic distribution. Two patients with extensive petaloid seborrheic dermatitis of the face are presented who quickly responded to a typical regimen for seborrheic dermatitis. Recognition of petaloid seborrheic dermatitis will prevent misdiagnosis and improper treatment of this common condition.","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46388052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Stein Gold, L. Kircik, E. Tanghetti, H. Baldwin, M. Gold, Z. Draelos, E. Lain, D. Pariser, N. Sadick, R. Pillai, V. Bhatt
{"title":"Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: Randomized Phase 2 and Phase 3 Studies of the First Triple-Combination Drug","authors":"L. Stein Gold, L. Kircik, E. Tanghetti, H. Baldwin, M. Gold, Z. Draelos, E. Lain, D. Pariser, N. Sadick, R. Pillai, V. Bhatt","doi":"10.25251/skin.7.supp.159","DOIUrl":"https://doi.org/10.25251/skin.7.supp.159","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47659609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Stein Gold, A. Pinter, A. Armstrong, L. Iversen, M. Praestegaard, M. Augustin
{"title":"Phase 3 Trial Demonstrating High Efficacy, Favourable Safety, and Convenience of a Novel Calcipotriene and Betamethasone Dipropionate Cream","authors":"L. Stein Gold, A. Pinter, A. Armstrong, L. Iversen, M. Praestegaard, M. Augustin","doi":"10.25251/skin.7.supp.128","DOIUrl":"https://doi.org/10.25251/skin.7.supp.128","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46109755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Singh, Stanislav N Tolkachjov, Aaron S. Farberg
{"title":"Integration of the 40-Gene Expression Profile (40-GEP) for Management and Treatment of High-risk Cutaneous Squamous Cell Carcinoma (cSCC): A Real-world Algorithm","authors":"G. Singh, Stanislav N Tolkachjov, Aaron S. Farberg","doi":"10.25251/skin.7.supp.165","DOIUrl":"https://doi.org/10.25251/skin.7.supp.165","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44728252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Gamal, M. Elshaer, L. Long, Thomas McCormick, B. Elewski, M. Ghannoum
{"title":"Efinaconazole in the Age of Antifungal Resistance","authors":"A. Gamal, M. Elshaer, L. Long, Thomas McCormick, B. Elewski, M. Ghannoum","doi":"10.25251/skin.7.supp.195","DOIUrl":"https://doi.org/10.25251/skin.7.supp.195","url":null,"abstract":"","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44845596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful Treatment of Refractory Hailey-Hailey Disease with Dupilumab: A Case Report","authors":"A. King, Nikita Wong, Geoffrey A Potts","doi":"10.25251/skin.7.2.15","DOIUrl":"https://doi.org/10.25251/skin.7.2.15","url":null,"abstract":"Hailey-Hailey disease (HHD) is an autosomal dominant blistering dermatosis with incomplete penetrance caused by an ATP2C1 gene mutation. Currently, there is no cure for HHD; however therapeutic options aim to minimize the exacerbating factors and manage patients’ symptoms. A 58-year-old male presented with a 10-year history of biopsy-proven HHD. He was seen consistently over the course of nine years with multiple flares a year consisting of pruritic and painful intertriginous plaques with involvement of the chest, upper arms, and back. His disease was recalcitrant to topicals, oral and topical antibiotics, phototherapy, and systemic corticosteroids. He was started on dupilumab and noticed significant improvement. We present a case of HHD recalcitrant to various modalities of treatment. Our description of rapid improvement with dupilumab suggests a role for Th2 signaling in the pathophysiology of HHD. We propose that dupilumab works for HHD due to the significant skin barrier dysfunction, similar to atopic dermatitis, and consider whether inflammation plays an earlier role in the disease. Although used for an off-label purpose, in this case, further studies should assess the clinical response and safety of patients with recalcitrant HHD treated with dupilumab.","PeriodicalId":74803,"journal":{"name":"Skin (Milwood, N.Y.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43291401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}