Shanghai chest最新文献_第10页

Thoracoscopic bidirectional S10 segmentectomy: a case report 胸腔镜双向S10节段切除术1例

Shanghai chest Pub Date : 2021-01-01 DOI: 10.21037/shc-21-18

Min Zhang, G. Fu, Xu Chen, M. Ge

引用次数: 0

Lung resection as part of multi-modality treatment for stage IV lung cancer 肺切除术作为IV期肺癌多模式治疗的一部分

Shanghai chest Pub Date : 2021-01-01 DOI: 10.21037/shc-22-8

M. Taylor, G. Whittaker, M. Evison, R. Booton, S. Grant, F. Granato

{"title":"Lung resection as part of multi-modality treatment for stage IV lung cancer","authors":"M. Taylor, G. Whittaker, M. Evison, R. Booton, S. Grant, F. Granato","doi":"10.21037/shc-22-8","DOIUrl":"https://doi.org/10.21037/shc-22-8","url":null,"abstract":"Background: Some observational studies have demonstrated reasonable survival outcomes for selected patients with stage IV lung cancer undergoing lung resection as part of multi-modality treatment. We review our experience of stage IV lung cancer patients undergoing therapeutic lung resection. Methods: A single-centre retrospective review of 19 patients with stage IV lung cancer undergoing therapeutic surgical resection as part of multi-modality treatment between 2012 and 2018 was undertaken. Reported outcomes included adherence to planned treatment regimens, adherence to local policy of treatment sequencing and 1-, 2- and 3-year survival. Results: Three patients with cranial metastases underwent initial radiotherapy to the brain. Of the remaining 16 patients, nine were treated with systemic therapy initially and 77.8% (n=7/9) completed all planned treatment modalities. Seven patients didn’t receive systemic therapy first and only 28.6% (n=2/7) of these patients completed all planned treatment modalities. Observed 1-, 2- and 3-year survival rates were 73.7% (n=14), 52.6% (n=10) and 47.4% (n=9), respectively. Conclusions: Multi-modality treatment in selected patients with stage IV lung cancer can be considered in selected patients with good mid-term results. A policy of systemic therapy first to ensure disease stability prior to local treatments may improve adherence to planned treatment strategy.","PeriodicalId":74794,"journal":{"name":"Shanghai chest","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44080833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iatrogenic oesophageal perforation 医源性食管穿孔

Shanghai chest Pub Date : 2021-01-01 DOI: 10.21037/SHC-21-10

S. Rozwadowski, E. Internullo

引用次数: 1

Complications of mediastinoscopy 纵隔镜检查并发症

Shanghai chest Pub Date : 2021-01-01 DOI: 10.21037/shc-21-20

L. Socci, S. Sionis, A. Sharkey

{"title":"Complications of mediastinoscopy","authors":"L. Socci, S. Sionis, A. Sharkey","doi":"10.21037/shc-21-20","DOIUrl":"https://doi.org/10.21037/shc-21-20","url":null,"abstract":": The most common mediastinoscopy technique is the video-assisted cervical mediastinoscopy (VAMLA) which is the modern version of the original mediastinoscopy described by Carlens in 1959. The extended-VAMLA and the trans-cervical extended mediastinal lymphadenectomy (TEMLA) techniques permit to biopsy a wider number of lymphonodal stations but they do carry out a high operative risk and are not widespread utilised. The most common perioperative complications in relation to a mediastinoscopy described in literature have been divided in 6 categories: (I) bleeding; (II) left laryngeal nerve palsy; (III) infection; (IV) pneumothorax; (V) tracheal perforation; (VI) oesophageal perforation. Of those, the first three categories are generally considered the most common ones. Of each category we describe tips to try to avoid the complication and the most common surgical management of the complication as presented in literature. In two categories as well, we present a patient’s case from our unit experience including related imaging. The mediastinoscopy is nowadays a routine procedure for a Thoracic Unit and commonly is managed as a day case procedure. Despite being considered a minor procedure it does need a specific training and carries out specific risks, which can vary from minor to catastrophic. The use of a video system permits a safe training and a safer and procedure. our service to coagulopathy","PeriodicalId":74794,"journal":{"name":"Shanghai chest","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41769452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combining radiation therapy and immunotherapy for lung cancers: a narrative review. 肺癌放射治疗与免疫治疗的联合治疗:综述。

Shanghai chest Pub Date : 2021-01-01 Epub Date: 2021-01-10 DOI: 10.21037/shc-20-66

Chirag Modi, Lyudmyla Berim, Lauren Isserow, Jyoti Malhotra, Malini Patel, John Langenfeld, Joseph Aisner, Doaa Almeldin, Salma K Jabbour

{"title":"Combining radiation therapy and immunotherapy for lung cancers: a narrative review.","authors":"Chirag Modi, Lyudmyla Berim, Lauren Isserow, Jyoti Malhotra, Malini Patel, John Langenfeld, Joseph Aisner, Doaa Almeldin, Salma K Jabbour","doi":"10.21037/shc-20-66","DOIUrl":"https://doi.org/10.21037/shc-20-66","url":null,"abstract":"<p><p>Lung cancer remains the leading cause of cancer morbidity and mortality worldwide among both men and women. While surgical resection remains the standard of care for early stage NSCLC, chemoradiation has been a mainstay of treatment for locally advanced non-small-cell lung cancer (LA-NSCLC) patients for decades. Consolidation immunotherapy has improved survival in this subset of patients after conventional chemoradiation, and has emerged as the new standard. The synergy between immunotherapy and radiation, as well as ongoing research on the effects of radiation on the immune system, allows for the exploration of new avenues in the treatment of LA-NSCLC. In addition to the use of durvalumab as consolidative systemic therapy after concurrent chemoradiotherapy for Stage III NSCLC, other combination regimens have been shown to be effective in various disease stages in preclinical and clinical studies. These regimens include CTLA-4 and PD/PDL-1 checkpoint inhibitors combined with radiation treatment. While these combined regimens have demonstrated efficacy, they are not without toxicity, and require additional evaluation when combined with radiation. In this review, we have summarized the immunostimulatory and immunosuppressive effects of radiation therapy. We also evaluate the current evidence and ongoing research supporting the combination of radiotherapy and immunotherapy across early to LA-NSCLC.</p>","PeriodicalId":74794,"journal":{"name":"Shanghai chest","volume":"5 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bb/46/nihms-1645004.PMC7842553.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25316618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Elective perioperative veno-venous extracorporeal membrane oxygenation for the management of severe tracheal stenosis: a case report 选择性围手术期静脉-静脉体外膜氧合治疗严重气管狭窄1例

Shanghai chest Pub Date : 2021-01-01 DOI: 10.21037/shc-22-4

Christopher G. Lui, Yael Bensoussan, K. O'Dell, Diana H. Yu

引用次数: 0

Successful lung cancer screening more than just scanning persons at risk 成功的癌症筛查不仅仅是扫描有风险的人

Shanghai chest Pub Date : 2021-01-01 DOI: 10.21037/shc-2021-03

W. Voigt, H. Prosch

引用次数: 0

Role of partial pleurectomy and extended pleurectomy/ decortication in mesothelioma: a narrative review 部分胸膜切除和扩展胸膜切除/去皮在间皮瘤中的作用:一个叙述性的回顾

Shanghai chest Pub Date : 2021-01-01 DOI: 10.21037/shc-21-34

F. Petrella, M. Casiraghi, Claudia Bardoni, L. Bramati, A. Cara, L. Spaggiari