Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress最新文献_第6页

1. The Case Of The Vanishing Marginals 1. 边际消失的案例

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-12-31 DOI: 10.12987/9780300161816-005

引用次数: 0

6. Back To The Vanishing Marginals: Some Loose Ends 6. 回到消失的边缘:一些未解决的问题

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-12-31 DOI: 10.12987/9780300161816-010

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3. The Vanishing Marginals: Who Done It? 3.消失的边缘:谁干的?

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-12-31 DOI: 10.12987/9780300161816-007

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7. Some Circumstantial Evidence Surrounding The Rise Of The Washington Establishment 7. 围绕华盛顿建制派崛起的一些间接证据

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-12-31 DOI: 10.12987/9780300161816-011

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11. Confusions And Clarifications 11. 混淆和澄清

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-12-31 DOI: 10.12987/9780300161816-016

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13. Looking Back and Looking Ahead 13. 回顾与展望

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-12-31 DOI: 10.12987/9780300161816-018

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State Estimation Under Correlated Partial Measurement Losses: Implications for Weight Control Interventions. 相关部分测量损失下的状态估计：体重控制干预的意义

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-07-01 Epub Date: 2017-10-18 DOI: 10.1016/j.ifacol.2017.08.2347

Penghong Guo, Daniel E Rivera, Jennifer S Savage, Danielle S Downs

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引用次数: 0

Nonlinear Model Predictive Control For Circadian Entrainment Using Small-Molecule Pharmaceuticals. 利用小分子药物进行昼夜节律调节的非线性模型预测控制

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-07-01 Epub Date: 2017-10-18 DOI: 10.1016/j.ifacol.2017.08.1596

John H Abel, Ankush Chakrabarty, Francis J Doyle

{"title":"Nonlinear Model Predictive Control For Circadian Entrainment Using Small-Molecule Pharmaceuticals.","authors":"John H Abel, Ankush Chakrabarty, Francis J Doyle","doi":"10.1016/j.ifacol.2017.08.1596","DOIUrl":"10.1016/j.ifacol.2017.08.1596","url":null,"abstract":"Recent in vitro studies have identified small-molecule pharmaceuticals effecting dose-dependent changes in the mammalian circadian clock, providing a novel avenue for control. Most studies employ light for clock control, however, pharmaceuticals are advantageous for clock manipulation through reduced invasiveness. In this paper, we employ a mechanistic model to predict the phase dynamics of the mammalian circadian oscillator under the effect of the pharmaceutical under investigation. These predictions are used to inform a constrained model predictive controller (MPC) to compute appropriate dosing for clock re-entrainment. Constraints in the formulation of the MPC problem arise from variation in the phase response curves (PRCs) describing drug effects, and are in many cases non-intuitive owing to the nonlinearity of oscillator phase response effects. We demonstrate through in-silico experiments that it is imperative to tune the MPC parameters based on the drug-specific PRC for optimal phase manipulation.","PeriodicalId":74547,"journal":{"name":"Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress","volume":"50 1","pages":"9864-9870"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034286/pdf/nihms-1688215.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25581608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

System Identification Algorithm for Non-Uniformly Sampled Data. 非均匀采样数据的系统识别算法

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2017-07-01 DOI: 10.1016/j.ifacol.2017.08.1460

Korkut Bekiroglu, Constantino Lagoa, Stephanie T Lanza, Mario Sznaier

引用次数: 0

The Business of America Is Lobbying 美国的商业是游说

Proceedings of the IFAC World Congress. International Federation of Automatic Control. World Congress Pub Date : 2015-05-01 DOI: 10.1093/ACPROF:OSO/9780190215514.003.0010

Lee Drutman

引用次数: 132