{"title":"Infection rates in adult and pediatric inpatients when i.v. sets are changed every 72 hours.","authors":"S L Baker, R J Kuhn, S Berry","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7452,"journal":{"name":"American journal of hospital pharmacy","volume":"51 24","pages":"3076, 3078"},"PeriodicalIF":0.0,"publicationDate":"1994-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18856124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Opportunities for alliances between industry and pharmacy.","authors":"Gerald B. Rosenberg","doi":"10.1093/AJHP/51.24.3061","DOIUrl":"https://doi.org/10.1093/AJHP/51.24.3061","url":null,"abstract":"","PeriodicalId":7452,"journal":{"name":"American journal of hospital pharmacy","volume":"36 1","pages":"3061-5"},"PeriodicalIF":0.0,"publicationDate":"1994-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74695481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Staffing pharmacies to meet the demands of patient-oriented care.","authors":"D K McAllister, D A Rittenback","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7452,"journal":{"name":"American journal of hospital pharmacy","volume":"51 24","pages":"3024-5"},"PeriodicalIF":0.0,"publicationDate":"1994-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18856114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Venlafaxine: a heterocyclic antidepressant.","authors":"V L Ellingrod, P J Perry","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The pharmacology, pharmacokinetics, and clinical efficacy of venlafaxine hydrochloride, a new antidepressant, are described. Venlafaxine inhibits the reuptake of serotonin, norepinephrine, and, to a lesser extent, dopamine. In animal models, it does not significantly inhibit muscarinic, histaminic, or adrenergic receptor activity and does not inhibit monoamine oxidase. Venlafaxine is rapidly absorbed and metabolized in the liver to its active metabolite, O-desmethylvenlafaxine (ODV). Time to peak concentration is one to two hours for the parent compound and four to five hours for ODV. The pharmacokinetics of venlafaxine might be dose-dependent, although pharmacokinetic studies have had conflicting results. The major route of elimination is renal; thus, patients with renal dysfunction may require lower doses. In double-blind, placebo-controlled trials of venlafaxine for maintenance therapy, venlafaxine has shown effective antidepressant activity in severely ill patients with major depression. Antidepressant effectiveness may be apparent within two weeks; this finding needs to be replicated. The dosage is 75-375 mg/day administered in two or three divided doses. The strength of the antidepressant response may be correlated with increasing dosage. Nausea is the most commonly reported adverse drug reaction (ADR). Others include somnolence, dizziness, dry mouth, and sweating. All ADRs have commonly occurred at the beginning of therapy and decreased with time. Overall, venlafaxine is well tolerated. Venlafaxine is as effective as other available antidepressants. It may cause fewer anticholinergic, antihistaminic, and antiadrenergic ADRs and may have a quicker onset of therapeutic action than existing antidepressants.</p>","PeriodicalId":7452,"journal":{"name":"American journal of hospital pharmacy","volume":"51 24","pages":"3033-46"},"PeriodicalIF":0.0,"publicationDate":"1994-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18856117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subtleties of managing acetaminophen poisoning.","authors":"S. R. Rose","doi":"10.1093/AJHP/51.24.3065","DOIUrl":"https://doi.org/10.1093/AJHP/51.24.3065","url":null,"abstract":"","PeriodicalId":7452,"journal":{"name":"American journal of hospital pharmacy","volume":"40 1","pages":"3065-8"},"PeriodicalIF":0.0,"publicationDate":"1994-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80159424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving care and reducing costs in the ICU.","authors":"M F Ivey","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7452,"journal":{"name":"American journal of hospital pharmacy","volume":"51 24","pages":"3029"},"PeriodicalIF":0.0,"publicationDate":"1994-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18856116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stability of paclitaxel in 5% dextrose injection or 0.9% sodium chloride injection at 4, 22, or 32 degrees C.","authors":"Q Xu, L A Trissel, J F Martinez","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7452,"journal":{"name":"American journal of hospital pharmacy","volume":"51 24","pages":"3058-60"},"PeriodicalIF":0.0,"publicationDate":"1994-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18856121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}