{"title":"Velocity-weighting to prevent controller-induced hypoglycemia in MPC of an artificial pancreas to treat T1DM.","authors":"Ravi Gondhalekar, Eyal Dassau, Francis J Doyle","doi":"10.1109/ACC.2015.7170967","DOIUrl":"https://doi.org/10.1109/ACC.2015.7170967","url":null,"abstract":"<p><p>The design of a Model Predictive Control (MPC) strategy for the closed-loop operation of an Artificial Pancreas (AP) to treat type 1 diabetes mellitus is considered. The contribution of this paper is to propose a velocity-weighting mechanism, within an MPC problem's cost function, that facilitates penalizing predicted hyperglycemic blood-glucose excursions based on the predicted blood-glucose levels' rates of change. The method provides the control designer some freedom for independently shaping the AP's <i>uphill</i> versus <i>downhill</i> responses to hyperglycemic excursions; of particular emphasis in this paper is the downhill response. The proposal aims to tackle the dangerous issue of controller-induced hypoglycemia following large hyperglycemic excursions, e.g., after meals, that results in part due to the large delays of subcutaneous glucose sensing and subcutaneous insulin infusion - the case considered here. The efficacy of the proposed approach is demonstrated using the University of Virginia/Padova metabolic simulator with both unannounced and announced meal scenarios.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2015 ","pages":"1635-1640"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ACC.2015.7170967","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34975380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Florian Straußberger, M. Schwab, Tristan Braun, J. Reuter
{"title":"Position estimation in electro-magnetic actuators using a modified discrete time class A/B model reference approach","authors":"Florian Straußberger, M. Schwab, Tristan Braun, J. Reuter","doi":"10.1109/ACC.2014.6858841","DOIUrl":"https://doi.org/10.1109/ACC.2014.6858841","url":null,"abstract":"In this paper, the use of a discrete time model reference adaptive approach is proposed for estimating the armature position of electro-magnetic actuators. It is assumed that current and voltage measurements are available, only. It is shown that by identification of the parameters of the electrical subsystem, a unique and accurate estimate for the armature position can be obtained. To this end two discrete time MRAS methods are combined in order to take advantage of complementary properties. It is shown in practical experiments that with this approach robust and fast estimation of the electrical parameters is achieved and the position estimation can thus be solved in real world environments.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"117 1","pages":"3686-3691"},"PeriodicalIF":0.0,"publicationDate":"2014-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73155304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Greetings from the AACC President","authors":"T. Samad","doi":"10.1109/ACC.2014.6858566","DOIUrl":"https://doi.org/10.1109/ACC.2014.6858566","url":null,"abstract":"all participants to the 2014 American Control Conference. It’s been over three decades since the first ACC was held (in Arlington, Virginia, 1982) and since then the annual conference has become an established, selective international event covering all aspects of research and development in control systems. ACCs now attract around 1,300 participants representing academia (including graduate students), industry, and government organizations. Only a slim majority of the attendees are from the United States. The centerpiece of the conference is the technical program, and this year’s ACC will feature about 1,000 presentations on developments in diverse areas of control, theoretical as well as applied. Also on offer are pre-conference workshops, special and “micro” sessions on technical and other topics, exhibits and recruitment opportunities, and the AACC Awards Ceremony. The action spills over into the hallways and break areas too, where professional connections and friendships are made and renewed, collaboration prospects broached and firmed up, and much “catching up” undertaken. It’s hard to do any of these things well within the e-cocoons in which we seem to spend so much of our work (and personal) lives you’ll be glad you came!","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"1 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2014-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88875483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Greetings and thanks from the general chair","authors":"D. Tilbury","doi":"10.1109/ACC.2014.6858578","DOIUrl":"https://doi.org/10.1109/ACC.2014.6858578","url":null,"abstract":"The planning for an ACC takes several years. When I was invited to organize a “West Coast” ACC, I almost immediately chose Portland. The 2005 ACC here was memorable, and Portland is well-known as a friendly and attractive city. It has a great downtown, with short walkable blocks, lots of shopping (no sales tax), and great restaurants – from the food courts to the high end with everything in between! The river invites walking or biking, and the views of the mountain (on sunny days) can’t be beat.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"3 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2014-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77315461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Technical program overview","authors":"G. Balas","doi":"10.1109/ACC.2014.6858572","DOIUrl":"https://doi.org/10.1109/ACC.2014.6858572","url":null,"abstract":"Welcome to Portland! On behalf of the Operating Committee of the 2014 American Control Conference, I am delighted to welcome you to the conference!","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"37 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2014-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90591480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MPC Design for Rapid Pump-Attenuation and Expedited Hyperglycemia Response to Treat T1DM with an Artificial Pancreas.","authors":"Ravi Gondhalekar, Eyal Dassau, Francis J Doyle","doi":"10.1109/ACC.2014.6859247","DOIUrl":"10.1109/ACC.2014.6859247","url":null,"abstract":"<p><p>The design of a Model Predictive Control (MPC) strategy for the closed-loop operation of an Artificial Pancreas (AP) for treating Type 1 Diabetes Mellitus (T1DM) is considered in this paper. The contribution of this paper is to propose two changes to the usual structure of the MPC problems typically considered for control of an AP. The first proposed change is to replace the symmetric, quadratic input cost function with an asymmetric, quadratic function, allowing negative control inputs to be penalized less than positive ones. This facilitates rapid pump-suspensions in response to predicted hypoglycemia, while simultaneously permitting the design of a conservative response to hyperglycemia. The second proposed change is to penalize the velocity of the predicted glucose level, where this velocity penalty is based on a cost function that is again asymmetric, but additionally state-dependent. This facilitates the accelerated response to acute, persistent hyperglycemic events, e.g., as induced by unannounced meals. The novel functionality is demonstrated by numerical examples, and the efficacy of the proposed MPC strategy verified using the University of Padova/Virginia metabolic simulator.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2014 ","pages":"4224-4230"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ACC.2014.6859247","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34975378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuwen Dong, Sunil Deshpande, Daniel E Rivera, Danielle S Downs, Jennifer S Savage
{"title":"Hybrid Model Predictive Control for Sequential Decision Policies in Adaptive Behavioral Interventions.","authors":"Yuwen Dong, Sunil Deshpande, Daniel E Rivera, Danielle S Downs, Jennifer S Savage","doi":"10.1109/ACC.2014.6859462","DOIUrl":"https://doi.org/10.1109/ACC.2014.6859462","url":null,"abstract":"<p><p>Control engineering offers a systematic and efficient method to optimize the effectiveness of individually tailored treatment and prevention policies known as adaptive or \"just-in-time\" behavioral interventions. The nature of these interventions requires assigning dosages at categorical levels, which has been addressed in prior work using Mixed Logical Dynamical (MLD)-based hybrid model predictive control (HMPC) schemes. However, certain requirements of adaptive behavioral interventions that involve sequential decision making have not been comprehensively explored in the literature. This paper presents an extension of the traditional MLD framework for HMPC by representing the requirements of sequential decision policies as mixed-integer linear constraints. This is accomplished with user-specified dosage sequence tables, manipulation of one input at a time, and a switching time strategy for assigning dosages at time intervals less frequent than the measurement sampling interval. A model developed for a gestational weight gain (GWG) intervention is used to illustrate the generation of these sequential decision policies and their effectiveness for implementing adaptive behavioral interventions involving multiple components.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2014 ","pages":"4198-4203"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ACC.2014.6859462","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33015670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kevin P Timms, Daniel E Rivera, Megan E Piper, Linda M Collins
{"title":"A Hybrid Model Predictive Control Strategy for Optimizing a Smoking Cessation Intervention.","authors":"Kevin P Timms, Daniel E Rivera, Megan E Piper, Linda M Collins","doi":"10.1109/ACC.2014.6859466","DOIUrl":"https://doi.org/10.1109/ACC.2014.6859466","url":null,"abstract":"<p><p>The chronic, relapsing nature of tobacco use represents a major challenge in smoking cessation treatment. Recently, novel intervention paradigms have emerged that seek to adjust treatments over time in order to meet a patient's changing needs. This article demonstrates that Hybrid Model Predictive Control (HMPC) offers an appealing framework for designing these optimized, time-varying smoking cessation interventions. HMPC is a particularly appropriate approach as it recognizes that intervention doses must be assigned in predetermined, discrete units while retaining receding-horizon, constraint-handling, and combined feedback and feedforward capabilities. Specifically, an intervention algorithm is developed here in which counseling and two pharmacotherapies are manipulated to reduce daily smoking and craving levels. The potential usefulness of such an intervention is illustrated through simulated treatment of a quit attempt in a hypothetical patient, which highlights that prioritizing reduction in craving over total daily smoking levels significantly reduces craving levels, suppresses relapse, and successfully rejects time-varying disturbances such as stress, all while adhering to several practical operational constraints and resource use considerations.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2014 ","pages":"2389-2394"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ACC.2014.6859466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32819215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Local E-optimality Conditions for Trajectory Design to Estimate Parameters in Nonlinear Systems.","authors":"Andrew D Wilson, Todd D Murphey","doi":"10.1109/ACC.2014.6858649","DOIUrl":"https://doi.org/10.1109/ACC.2014.6858649","url":null,"abstract":"<p><p>This paper develops an optimization method to synthesize trajectories for use in the identification of system parameters. Using widely studied techniques to compute Fisher information based on observations of nonlinear dynamical systems, an infinite-dimensional, projection-based optimization algorithm is formulated to optimize the system trajectory using eigenvalues of the Fisher information matrix as the cost metric. An example of a cart-pendulum simulation demonstrates a significant increase in the Fisher information using the optimized trajectory with decreased parameter variances shown through Monte-Carlo tests and computation of the Cramer-Rao lower bound.</p>","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"2014 ","pages":"443-450"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ACC.2014.6858649","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32771797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Communication through motion in dance with topological constraints","authors":"Kayhan Özcimder","doi":"10.1109/ACC.2014.6859167","DOIUrl":"https://doi.org/10.1109/ACC.2014.6859167","url":null,"abstract":"This paper summarizes work that investigates human interactions in terms of communication through motion in cooperative control. We are interested in multi-agent distributed control models with a shared goal and with the agents being required to accomplish secondary objectives. The study presented here extends the earlier work on the analysis of leader-follower interactions in salsa. The move transitions in salsa are described by simple rules suggested by topological knot theory. The initial and final poses of each move in the dance are represented by link diagrams. The link invariant Alexander Polynomial is calculated for classified link diagrams so that the physical motion primitives in dance are described as polynomial function manipulations. The size of the alphabet for the dance moves given in earlier work is extended by introducing three new moves. The leaders' decision process in a transition system is discussed and it is compared with the prior models which had fewer moves. Complexity metrics are proposed to capture the new alphabet and the proficiency hierarchy in the dance.","PeriodicalId":74510,"journal":{"name":"Proceedings of the ... American Control Conference. American Control Conference","volume":"11 1","pages":"178-183"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80608957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}