Parasitologia (Basel, Switzerland)最新文献_第8页

The Diagnosis, Treatment, Surveillance and Control of Cystic Echinococcosis in the Province of Rio Negro: The “One-Health” Model 黑鬼省囊性包虫病的诊断、治疗和监测与控制:“一个健康”模式

Parasitologia (Basel, Switzerland) Pub Date : 2021-09-23 DOI: 10.3390/parasitologia1040019

G. Mujica, L. Uchiumi, D. Araya, J. C. Salvitti, J. Labanchi, M. Sobrino, E. Herrero, Oscar Panomarenko, P. Blanco, G. Talmón, Hebe Tissot, Claudia Grizmado, M. Arezo, M. Seleiman, C. Mercapide, E. Larrieu

{"title":"The Diagnosis, Treatment, Surveillance and Control of Cystic Echinococcosis in the Province of Rio Negro: The “One-Health” Model","authors":"G. Mujica, L. Uchiumi, D. Araya, J. C. Salvitti, J. Labanchi, M. Sobrino, E. Herrero, Oscar Panomarenko, P. Blanco, G. Talmón, Hebe Tissot, Claudia Grizmado, M. Arezo, M. Seleiman, C. Mercapide, E. Larrieu","doi":"10.3390/parasitologia1040019","DOIUrl":"https://doi.org/10.3390/parasitologia1040019","url":null,"abstract":"Cystic Echinococcosis (CE) is an endemo-epidemic disease in the Rio Negro Province, República Argentina. Due to the number of cases, the length of hospital stays after surgery and its associated mortality, it is a serious public health problem that generates high costs for the health system. Oriented towards its control, primary prevention activities have been carried out since 1980, based on the deworming of dogs and the vaccination of lambs; secondary prevention has consisted in the actively search for cases through serological or ultrasonographic screening; and tertiary prevention has been based on timely treatment, either by surgery or by medical treatment with albendazole. All these prevention activities have been carried out under the concept and strategies of the “One Health” model, through both inter-institutional and interdisciplinary work, as well as with the support, commitment and critical participation of the community. As a result, an important drop has been observed in the prevalence of CE in humans and in its lethality (0.5% in 1997–2020, no deaths in the last two years); moreover, an important decrease has been observed in costs to the health system, due to the reduction of hospitalizations and the number of surgeries.","PeriodicalId":74398,"journal":{"name":"Parasitologia (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42798255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Recent Advances in the Control of Helminths of Domestic Animals by Helminthophagous Fungi 食虫真菌防治家畜寄生虫的研究进展

Parasitologia (Basel, Switzerland) Pub Date : 2021-09-07 DOI: 10.3390/parasitologia1030018

J. V. Araújo, F. R. Braga, P. Mendoza-de-Gives, A. Paz-Silva, V. Vilela

{"title":"Recent Advances in the Control of Helminths of Domestic Animals by Helminthophagous Fungi","authors":"J. V. Araújo, F. R. Braga, P. Mendoza-de-Gives, A. Paz-Silva, V. Vilela","doi":"10.3390/parasitologia1030018","DOIUrl":"https://doi.org/10.3390/parasitologia1030018","url":null,"abstract":"This review describes the advances acquired and proven in the use of helminthophagous fungi in the control of gastrointestinal helminth parasites in domestic animals. Old and well-known premises about parasitic epidemiology and the factors that can interfere with the best performance of biological control are mentioned. Some of the most promising fungi are Duddingtonia flagrans from the predatory fungi group and Pochonia chamydosporia and Mucor circinelloides from the ovicidal fungi group. These fungi produce resistance spores called chlamidospores. Bioverm® and BioWorma®, based on the fungus D. flagrans, are available as commercial. Biotechnological products such as nanoparticles and obtaining primary and secondary metabolites have already been obtained from these fungi. Because they have different mechanisms of action, ovicidal and predatory fungi, when used together, can present a complementary and synergistic action in the biological control of helminths. Therefore, future research in the search for new formulations, the association of fungi from different groups, extraction of new molecules, and nanoparticles of these fungi in the control of helminths in various domestic animals are desired.","PeriodicalId":74398,"journal":{"name":"Parasitologia (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45006813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Micro-Epidemiological Investigation of Echinococcus multilocularis in Wild Hosts from an Endemic Area of Southwestern Hungary 匈牙利西南部某地方病流行区野生宿主多房棘球蚴的微观流行病学调查

Parasitologia (Basel, Switzerland) Pub Date : 2021-09-01 DOI: 10.3390/parasitologia1030017

T. Halász, G. Nagy, I. Nagy, Á. Csivincsik

引用次数: 2

Interactions between Parasitic Infections and Reproductive Efficiency in Horses 马寄生虫感染与繁殖效率的相互作用

Parasitologia (Basel, Switzerland) Pub Date : 2021-08-13 DOI: 10.3390/parasitologia1030016

P. Tyrnenopoulou, Petros T. Boufis, G. Fthenakis, E. Papadopoulos

引用次数: 4

Surveillance of Host-Seeking Ticks in the Flint Hills Region (USA) and Associations with Environmental Determinants 美国Flint Hills地区寻找宿主蜱的监测及其与环境决定因素的关系

Parasitologia (Basel, Switzerland) Pub Date : 2021-08-07 DOI: 10.3390/parasitologia1030015

M. Spare, G. Boorgula, D. Thomson, J. Bai, D. Goodin, G. Anderson, R. W. Stich, Ali Hroobi, Savannah Wilson, Alex Staggs, Ashley A. Bowers, Alexandra Hamm, J. Tatman, R. Raghavan

{"title":"Surveillance of Host-Seeking Ticks in the Flint Hills Region (USA) and Associations with Environmental Determinants","authors":"M. Spare, G. Boorgula, D. Thomson, J. Bai, D. Goodin, G. Anderson, R. W. Stich, Ali Hroobi, Savannah Wilson, Alex Staggs, Ashley A. Bowers, Alexandra Hamm, J. Tatman, R. Raghavan","doi":"10.3390/parasitologia1030015","DOIUrl":"https://doi.org/10.3390/parasitologia1030015","url":null,"abstract":"Diversity and phenology of host-seeking ticks were studied in the Flint Hills region of the USA, which is a prominent region for raising beef cattle. Between a two-year period from 2015–2017, ticks were collected using the dragging method from 9 distant locations, 6 of which were studied seasonally and 3 continuously throughout the study period. Of the 10,055 ticks collected, 76.5% were the Lonestar tick (Amblyomma americanum), 14% were American dog tick (Dermacentor variabilis), and 9.1% were Gulf Coast tick (A. maculatum). The blacklegged tick, Ixodes scapularis were also found, albeit in low numbers. The host-seeking activity of all three predominant tick species peaked once during the late spring, summer months in the region. The phenology of all ticks was positively associated with accumulated temperature and photoperiod. Additionally, the Normalized Vegetation Difference Index (NDVI) was associated with A. americanum, and saturation deficit and relative humidity were negatively associated with D. variabilis and A. maculatum tick phenology, respectively. This finding is useful to predict the times during a year in which cattle are at higher risk for exposure to these ticks and associated pathogens.","PeriodicalId":74398,"journal":{"name":"Parasitologia (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45604861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Field Evaluation of Preventive Efficacy of Monthly Multimodal Prophylactic Treatment (Milbactor® and Vectra® 3D) against Dirofilaria spp. in Dogs 每月多模式预防治疗（Milbactor®和Vectra®3D）对狗的Dirofilaria spp.预防效果的现场评估

Parasitologia (Basel, Switzerland) Pub Date : 2021-07-30 DOI: 10.3390/parasitologia1030014

Younes Laidoudi, H. Medkour, D. Tahir, H. Dahmana, J. Marié, M. Varloud, O. Mediannikov, B. Davoust

{"title":"Field Evaluation of Preventive Efficacy of Monthly Multimodal Prophylactic Treatment (Milbactor® and Vectra® 3D) against Dirofilaria spp. in Dogs","authors":"Younes Laidoudi, H. Medkour, D. Tahir, H. Dahmana, J. Marié, M. Varloud, O. Mediannikov, B. Davoust","doi":"10.3390/parasitologia1030014","DOIUrl":"https://doi.org/10.3390/parasitologia1030014","url":null,"abstract":"Dirofilaria immitis and Dirofilaria repens are mosquito-borne pathogens responsible for dirofilariasis in humans and animals. Their transmission and spread depend on the activity of vectors and the frequency of hosts in a given area. Here, we investigated the efficacy of a monthly multimodal prophylactic (MMP) strategy against canine dirofilariasis on Corsica Island (France). The study was conducted as evidence of an efficacy trial in which eighty dogs were divided into two groups: (i) one test group consisted of 25 dogs under the MMP [per-os administration of 1.5 tablets of milbemycin-oxime-praziquantel (Milbactor®) and a topical line-on application of a 3.6 mL solution of dinotefuran-permethrin-pyriproxyfen (Vectra® 3D)] and (ii) a control group under different real-life prophylactic treatments (RLP) based on the use of ectoparasiticides (different formulations: deltamethrin, fluralaner, fipronil) and/or macrocyclic lactone-based products (milbemycin-oxime/praziquantel, milbemycin-oxime, moxidectin) during the period from June to October 2017. All animals were followed up for one year, with blood collected at day 0, with follow-up at 6 and 12 months. Samples were tested for Dirofilaria spp. by species-specific qPCR. At the end of the study, no new case of Dirofilaria spp. infection was detected in the test group. However, the cumulative incidence of Dirofilaria spp. infection was 16.4% (n = 9; p = 0.027) in the control group. The data illustrate that, in contrast to RLP treatment, which failed to protect at least 16.4% of dogs, the MMP based on the simultaneous administration of milbemycin oxime-praziquantel and dinotefuran-permethrin-pyriproxyfen efficiently protects dogs in a high-risk area from Dirofilaria spp. infection.","PeriodicalId":74398,"journal":{"name":"Parasitologia (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3390/parasitologia1030014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45500931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of a Commercial Disinfectant CLORICAN® on Acanthamoeba spp. and Naegleria fowleri Viability 商用消毒剂CLORICAN®对棘阿米巴和福氏奈格丽氏菌活力的影响

Parasitologia (Basel, Switzerland) Pub Date : 2021-07-13 DOI: 10.3390/PARASITOLOGIA1030013

I. Sifaoui, Aitor Rizo-Liendo, M. Reyes-Batlle, Iñigo Arberas-Jiménez, R. Rodríguez-Expósito, J. Piñero, J. Lorenzo-Morales

引用次数: 1

Molecular Tools for Diagnosis and Surveillance of Soil-Transmitted Helminths in Endemic Areas 用于诊断和监测地方性土壤传播蠕虫的分子工具

Parasitologia (Basel, Switzerland) Pub Date : 2021-07-07 DOI: 10.3390/PARASITOLOGIA1030012

M. Manuel, K. Ramanujam, S. Ajjampur

{"title":"Molecular Tools for Diagnosis and Surveillance of Soil-Transmitted Helminths in Endemic Areas","authors":"M. Manuel, K. Ramanujam, S. Ajjampur","doi":"10.3390/PARASITOLOGIA1030012","DOIUrl":"https://doi.org/10.3390/PARASITOLOGIA1030012","url":null,"abstract":"Soil-transmitted helminths (STH) including the hookworms Necator americanus and Ancylostoma spp., Ascaris lumbricoides, and Trichuris trichiura affect over 1.5 billion people worldwide and are estimated to have caused 1.9 million disability-adjusted life years (DALYs). With the concerted effort in expanding and improving targeted mass drug administration (MDA) programs over the past decade, along with decreasing prevalence, infections in several endemic areas tend to be of low intensity. Conventional microscopy-based methods recommended for the detection of STH in parasitological surveys have been shown to be less sensitive in these low-intensity settings. As communities progress towards STH elimination through MDA and improved sanitation, there is a pressing need for highly sensitive techniques that detect the true prevalence of STH to evaluate the effectiveness of ongoing programs and interventions. Molecular methods that involve analysis of DNA rather than the morphology of the organism are highly sensitive and specific, allowing for both quantitation and species discrimination. The following review discusses different sample collection strategies, pre-processing steps, DNA extraction platforms, and nucleic acid detection methods available for diagnosis and surveillance of STH. We have contrasted the utility of these molecular tools against conventional microscopy-based methods currently used in most endemic settings. While the detection methods are primarily qPCR based, several newer technologies have also become available along with automation and increased throughput, making these molecular tools increasingly cost-effective and potentially amenable for use in low-resource settings.","PeriodicalId":74398,"journal":{"name":"Parasitologia (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3390/PARASITOLOGIA1030012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49622199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Transmission of Soil Transmitted Helminthiasis in the Mifi Health District (West Region, Cameroon): Low Endemicity but Still Prevailing Risk Mifi卫生区（喀麦隆西部地区）土壤传播蠕虫病的传播：地方性较低，但风险仍然普遍

Parasitologia (Basel, Switzerland) Pub Date : 2021-06-24 DOI: 10.3390/parasitologia1030011

Laurentine Sumo, Esther Nadine Otiobo Atibita, E. Mache, T. Gangué, H. Nana-Djeunga

{"title":"Transmission of Soil Transmitted Helminthiasis in the Mifi Health District (West Region, Cameroon): Low Endemicity but Still Prevailing Risk","authors":"Laurentine Sumo, Esther Nadine Otiobo Atibita, E. Mache, T. Gangué, H. Nana-Djeunga","doi":"10.3390/parasitologia1030011","DOIUrl":"https://doi.org/10.3390/parasitologia1030011","url":null,"abstract":"The control of soil-transmitted helminthiasis (STH) in Cameroon is focused on large-scale deworming through annual mass drug administration (MDA) of albendazole or mebendazole to at-risk groups, principally pre-school and school-age children. After a decade of intervention, prevalence and intensity of infection have been significantly lowered, encouraging the paradigm shift from control to elimination. However, STH eggs are extremely resistant to environmental stressors and may survive for years in soils. It therefore appeared important to assess whether the risk of transmission was still prevailing, especially in a context where transmission of soil-transmitted helminths in the human population had almost been interrupted. A retrospective and a prospective cross-sectional surveys were conducted in five Health Areas of the Mifi Health District (West Region, Cameroon) to: (i) assess the trends in infestation rates over three-years (2018–2020) using health facility registers, and (ii) investigate, in 2020, the contamination rates of the environment by dissemination stages of soil-transmitted helminths using the sucrose centrifugal flotation method. The overall soil-transmitted helminth infestation rate was 4.9% (95% CI: 4.3–5.6), significantly lower than the overall soil contamination rate (12.0%; 95% CI: 8.2–17.2). These results are supportive of the low endemicity level of STHs in the Mifi Health District, but environmental pollution by dissemination stages of the parasites outlines that the risk of transmission is still persistent. It therefore appears compulsory to account for the environment when considering policy/recommendations for transmission interruption and stopping MDA, as it is in the case with vector-borne diseases.","PeriodicalId":74398,"journal":{"name":"Parasitologia (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3390/parasitologia1030011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43919058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Environmental Correlates of Prevalence of an Intraerythrocytic Apicomplexan Infecting Caribbean Damselfish 红细胞内ApiComplex感染加勒比大豆鱼患病率的环境相关性

Parasitologia (Basel, Switzerland) Pub Date : 2021-05-02 DOI: 10.3390/PARASITOLOGIA1020009

Akacia K. Halliday-Isaac, Jennilee B. Robinson, E. Cruz‐Rivera, A. Campbell, P. Sikkel

{"title":"Environmental Correlates of Prevalence of an Intraerythrocytic Apicomplexan Infecting Caribbean Damselfish","authors":"Akacia K. Halliday-Isaac, Jennilee B. Robinson, E. Cruz‐Rivera, A. Campbell, P. Sikkel","doi":"10.3390/PARASITOLOGIA1020009","DOIUrl":"https://doi.org/10.3390/PARASITOLOGIA1020009","url":null,"abstract":"Parasites are an integral part of coral reef ecosystems due to their influences on population dynamics, biodiversity, community structure, and food web connectivity. The Phylum Apicomplexa contains ubiquitous animal associates including the causative agents of globally important human diseases such as malaria and cryptosporidiosis. Despite their ubiquity, little is known about the biology, ecology, or distribution of these microorganisms in natural animal populations. In the US Virgin Islands, the dusky damselfish (Stegastes adustus) had a high but variable incidence of a Haemohormidium-like blood apicomplexan among 30 sites sampled. Microscopic analyses of blood smears allowed us to group these fish as infected, having low intensity infections, or uninfected. Regression analyses detected no significant differences in the condition indices (expressed as length–mass ratio). However, infection was clearly associated with potentially extremely high leukocyte counts among infected S. adustus that were not seen in uninfected fish. These results suggested the potential for some impact on the host. Linear mixed effects models indicated that S. adustus population density and meridional flow velocity were the main predictors of apicomplexan prevalence, with presence of other Stegastes species, population distance from watershed, zonal flow velocity, the complexity of the surrounding habitat, and season not showing any significant relationship with fish infection.","PeriodicalId":74398,"journal":{"name":"Parasitologia (Basel, Switzerland)","volume":"1 1","pages":"69-82"},"PeriodicalIF":0.0,"publicationDate":"2021-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3390/PARASITOLOGIA1020009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42337942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3